|   |
1 | . | . | . | . | . | . | . | . | 10 | . | . | . | . | |
. | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | |
|
|
|
. | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . |
Predicted Secondary structure |   |
|  |  |
|
|
|
|
|
|
|
|
|
|  | . |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
| . | . | . | . |
|
|  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
M | I | D | L | R | S | D | T | V | T | R | P | S | R | . |
A | M | L | E | A | M | M | A | A | P | V | G | D | D | V | Y | G | D | D | P | T | V | N | A | L | Q | D | Y | A | A | E | L | S | G | . |
. |
. |
. |
K | E | A | A | I | F | L | P | T | G | T | Q | A | N | L | V | A | L | L | S | H | C | E | R | G | E | E |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |
|   |
|   |
| . |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |
|   |   |   |
|
|   |   |   |
| . | . | . | . |   |
|   |   |   |   |   |   |
|
|
|   |
|   |   |   |
|
|   |
|   |   |   |   |
|   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|
|   |   |   |   |
|   |   |   |   |   |   |
|   |   |
|   |   |
|   |   |   |
|   |   | . | . | . | . | . |
|   |   |   |
|
|   |
|
|
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |
|   |   |
|   |
|   |   |   |
|
|   |   |   |   |   |   |
|   |   |   |
|
|   |
Template Sequence |   |
I | I | H | X | E | V | G | Q | P | G | T | G | A | P | R | G | A | V | E | A | L | A | K | S | L | E | . |
. |
. |
. |
. |
G | L | P | A | L | R | Q | R | I | A | R | L | Y | G | E | W | Y | G | V | D | L | D | P | G | R | V | V | I | T | P | G | S | S | G | G | F | L | L | A | F | T | A | L | F | D | S | G | D | R |
Template Known Secondary structure |   |
|  |  |
|
|
| S | S |
| S | S |
| S |
|  |  |  |  |  |  |  |  |  |  |  |
| . | . | . | . | . |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
| G | G | G |  |  |  |  | S | S |  |  |  |  |  |  |  |  |  |  |  |  |
|
| T | T |
|  |
Template Predicted Secondary structure |   |
 |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
| . | . | . | . | . |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
33 | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | |
|
|
|
|
. | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . |
  |
  |   |
76 | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
Y | I | V | G | Q | A | A | H | N | Y | L | F | E | A | G | G | A | A | V | L | G | S | I | Q | P | Q | P | I | D | A | A | A | D | G | T | L | P | L | D | K | V | A | M | K | I | K | P | D | D | I | H | F | A | R | T | K | L | L | S | L | E | N | T | H | N | G | K | V | L | P | R | E | Y | L | K | E | A | W | E | F |
Query Conservation |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|
|
|   |   |
|   |
|   |   |   | . | . | . |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . |   |   |   |
|   |   |   |   |
|   |
|
|
|
|   |   |   |   |   |   |   |
|   |   |
|   |   |   |
Template Sequence |   |
V | G | I | G | A | P | G | Y | P | S | Y | . |
. |
. |
R | Q | I | L | R | A | L | G | L | V | P | V | D | L | P | T | A | P | E | N | R | L | Q | P | V | P | A | D | F | A | G | L | D | . |
. |
. |
. |
. |
L | A | G | L | X | V | A | S | P | A | N | P | T | G | T | X | L | D | H | A | A | X | G | A | L | I | E | A |
Template Known Secondary structure |   |
 |  |  |  |  | S |
|
|  |  |  | . | . | . |  |  |  |  |  |  | T | T |
|  |  |  |  |  |  |
|
| G | G | G | T | T | S |
|
|  |  |  |  | T | T | S |
| . | . | . | . | . |
| S |  |  |  |  |  | S | S |
| T | T | T |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |
|
|
|
|  |  |  | . | . | . |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
118 | . | 120 | . | . | . | . | . | . | . | . | |
|
|
. | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | |
|
|
|
|
. | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . |
  |
  |   |
156 | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | |
. | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . |
Predicted Secondary structure |   |
 |  |
|
|
|
|  |  |  |  |  |  |
|
|  |  |
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
T | R | E | R | N | L | A | L | H | V | D | G | A | R | I | F | N | A | V | V | A | Y | G | C | E | L | K | E | . |
I | T | Q | Y | C | D | S | F | T | I | C | L | S | K | G | L | G | T | P | V | G | S | L | L | V | G | N | R | D | Y | I | K | R | A | I | R | W | R | K | M | T | G | G | G | M | R | Q | S | G | I | L |
Query Conservation |   |
  |   |   |   |   |   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |   |   |   |   |   |
|
|   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |
|
|   |   |   |   |   |
|   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
Template Sequence |   |
A | Q | A | Q | G | A | S | F | I | S | D | E | I | Y | H | G | I | E | Y | E | A | K | A | V | T | A | L | E | L | T | D | E | C | Y | V | I | N | S | F | S | K | Y | F | S | X | T | G | W | R | V | G | W | X | V | V | P | E | D | Q | V | R | V | V | E | R | I | A | Q | N | X | F | I | C | A | P | H | A | S | Q | V |
Template Known Secondary structure |   |
 |  |  | T | T |
|  |  |  |  |  |
| T | T | T | T |
| B | S | S | S |
|
|
|
| G | G | G | T |
| S | S | S |  |  |  |  |  | S | S | S | T | T |
|
| T | T | S |
|
|  |  |  |  |
|
| G | G | G |  |  |  |  |  |  |  |  |  |  | T | T |
|
|
|
|  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |
|
|
|  |  |  |
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . |
  |
  |   |
235 | . | . | . | . | 240 | . | |
. | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | |
|
. | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | |
|
. | . | . | . | . | . | 290 | . | . | . | . | . | . | . | |
. | . | 300 | . | . | . | . | |
|
|
|
Predicted Secondary structure |   |
 |  |  |  |  |  |  | . |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
| . | . |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
| . | . |
|
|
|  |  |  |  |  |  |  |  |  |  |
| . |
|
|  |  |  |
|
| . | . | . | . |
Query SS confidence |   |
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
| . |
. |
. |
. |
Query Sequence |   |
A | A | A | G | I | Y | A | . |
L | K | N | N | V | A | R | L | Q | E | D | H | D | N | A | A | W | M | A | E | Q | L | R | E | A | G | A | . |
. |
D | V | M | R | Q | D | T | N | M | L | F | V | R | V | G | . |
. |
E | E | N | A | A | A | L | G | E | Y | M | K | A | R | . |
N | V | L | I | N | A | S | . |
. |
. |
. |
Query Conservation |   |
|   |   |   |   |   |   | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   | . | . |   |   |   |   |   |   |
|   |   |   |
|   |   |   | . |
|
|   |
|   |   |   | . | . | . | . |
Alig confidence |   |
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
| . | . | . | . |
Template Conservation |   |
  |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |
|
|   |
|   |
|
|   |   |
|   |
Template Sequence |   |
A | A | L | A | A | L | D | C | D | A | E | L | Q | A | N | L | D | V | Y | K | A | N | R | K | L | X | L | E | R | L | P | K | A | G | F | T | R | I | A | P | P | D | G | A | F | Y | V | Y | A | D | V | S | D | L | T | D | D | S | R | A | F | A | A | E | I | L | E | K | A | G | V | A | V | T | P | G | L | D | F | D |
Template Known Secondary structure |   |
 |  |  |  |  | T | T |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
|
|
| B |
|
|
|
| B | T | T |  |  |  |  |  |
| T | T | T |
| S |
|  |  |  |  |  |  |  |  |  |  |  |  |
|  |  |
|  |  | G | G | G | T |
|
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |
|  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . |
  |
  |   |
|
|
|
|
|
305 | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . |
Predicted Secondary structure |   |
. | . | . | . | . |
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
. |
. |
. |
. |
. |
P | I | V | R | L | V | T | H | L | D | V | S | R | E | Q | L | A | E | V | A | A | H | W | R | A | F | L |
Query Conservation |   |
. | . | . | . | . |   |   |
|
|   |   |   |   |   |   |   |
|   |
|
|
|   |   |   |   |   |
|   |   |   |   |
|
Alig confidence |   |
. | . | . | . | . |
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |
|
|
|
|   |   | . | . |   |   |   |
|   |
|   |   |
|
|   |
|
|   |   |
|   |
Template Sequence |   |
P | E | R | G | A | G | T | L | R | F | S | Y | A | . |
. |
R | A | T | A | D | I | E | E | G | L | D | R | L | E | A | F | X |
Template Known Secondary structure |   |
T | T | T | G | G | G |  |  |  |  |  |
|
| . | . | S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|
|
|
|  |  |  |  |  |  |
| . | . |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
350 | . | . | . | . | . | . | . | . | . | 360 | . | . | |
|
. | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . |
  |