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Job DescriptionP75823
Confidence99.95%DateThu Jan 5 12:14:38 GMT 2012
Rank146Aligned Residues324
% Identity9%Templatec3e9kA_
PDB info PDB header:hydrolaseChain: A: PDB Molecule:kynureninase; PDBTitle: crystal structure of homo sapiens kynureninase-3-hydroxyhippuric acid2 inhibitor complex
Resolution1.70 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


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Query Sequence  MIDLRSDTVTRPSRAMLEAMMAAPV. . . . . . . . . . GDDVYGDDPTVNALQDYAAELSGK. . EAAIFLPTGTQANLVALLS
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Template Sequence  AIYFLGNSLGLQPKMVKTYLEEELDKWAKIAAYGHEVGKRPWITGDESIVGLMKDIVGANEKEIALMNALTVNLHLLMLS
Template Known Secondary structure 

BTTTS

B
TTGGGGGTSSSS
GGGTTGGGT

GGG
S
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   68.70.........80.........90.........100.........110.........120.........130.........140.......
 
   6970.. .......80.........90... ......100.........110.........120.........130.........
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Query Sequence  HCER. . . GEEYIVGQAAHNYLFEAGGAA. . . . . . VLGSIQPQPIDAAADGTLPLDKVAMKIKPDDIHFARTKLLSLENTH
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Template Sequence  FFKPTPKRYKILLEAKAFPSDHYAIESQLQLHGLNIEESMRMIKPREGEETLRIEDILEVIEKEGDS. IAVILFSGVHFY
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SSS
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TT
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GGG.SB
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   148.150.........160.........170.........180.........190.........200.........210.... .....220......
 
   140.........150.........160.........170.........180.........190.........200.........210.......
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Query Sequence  NGKVLPREYLKEAWEFTRERNLALHVDGARIFNAVVAYGCELKEITQYCDSFTICLSKGLGTPVGSLLVGNRDYIKRA. .
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Template Sequence  TGQHFN. . . IPAITKAGQAKGCYVGFDLAHAV. . . GNVELYLHDWGVDFACWCSYKYLNAGAGGIAGAFIHEKHAHTIKP
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BB

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TTTT...TTS


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SSSTT


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GGGTTTS

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   227..230.. .......240.........250..... ....260.........270.........280.........290.........300
 
   218.220.........230.........240.........250.........260...... ...
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Query Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . IRWRKMTGGGMRQSGILAAAGIYALKNNVARLQEDHDNAAWMAEQLREA. . GAD
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Template Sequence  ALVGWFGHELSTRFKMDNKLQLIPGVCGFRISNPPILLVCSLHASLEIFKQATMKALRKKSVLLTGYLEYLIKHNYGVVN
Template Known Secondary structure  SS

GGGB
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   301........310.........320.........330.........340.........350.........360.........370.........380
 
   270.... .....280.........290.........300. ........310. ........320.........330..
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Query Sequence  VMRQD. . . . . TNMLFVRVGEENAAALGEYMKARNVLI. . NASPIVRLVT. HLDVSREQLAEVAAHWRAFLA
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Template Sequence  IITPSHVEERGCQLTITFSV. PNKDVFQELEKRGVVCDKRNPNGIRVAPVPLYNSFHDVYKFTNLLTSILD
Template Known Secondary structure 
S
SSGGGB
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TTT
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   390.........400......... 410.........420.........430.........440.........450.........
 
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No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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