|   |
1 | . | . | . | . | . | . | . | . | 10 | . | . | |
|
|
|
. | . | . | . | . | . | . | 20 | . | . | . | |
. | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | |
. | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | |
|
|
70 | . |
Predicted Secondary structure |   |
|  |  |
|
|
|
|
|
|
|
|
| . | . | . | . |
|  |  |  |  |  |  |  |  |  |  | . |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
| . |
|
|
|  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  | . | . | . |  |
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
Query Sequence |   |
M | I | D | L | R | S | D | T | V | T | R | P | . |
. |
. |
. |
S | R | A | M | L | E | A | M | M | A | A | . |
P | V | G | D | D | V | Y | G | D | D | P | T | V | N | A | L | Q | D | Y | A | A | E | L | S | . |
G | K | E | A | A | I | F | L | P | T | G | T | Q | A | N | L | V | A | L | L | S | H | . |
. |
. |
C | E |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |
|   |
| . | . | . | . |   |
|   |   |   |   |
|   |   |   |
| . |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |
|   |   |   |
|
|   |   |   | . |
|   |
|   |   |   |   |   |   |
|
|
|   |
|   |   |   |
|
|   |
|   | . | . | . |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
Template Conservation |   |
  |
|
|   |   |   |   |   |   |   |   |   |
|
|
|   |   |
|   |
|   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|   |   |
|   |   |   |   |   |   |   |   |   |
|   |
|   |   |
|
|
|
|
|   |   |   |
|
|
|   |
|   |   |   |   |
|
Template Sequence |   |
Y | L | D | Y | V | M | S | W | G | P | L | I | L | G | H | A | H | P | K | V | L | A | R | V | R | E | T | L | E | R | G | L | T | F | G | A | P | S | P | L | E | V | A | L | A | K | K | V | K | R | A | Y | P | F | V | D | L | V | R | F | V | N | S | G | T | E | A | T | M | S | A | L | R | L | A | R | G | Y | T | G |
Template Known Secondary structure |   |
 |  |  | S | S | G | G | G | T | T |
| T | T |
| B | T |
|  |  |  |  |  |  |  |  |  |  |  |  | T |
| S |
|
| S | S |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
| T | T |
|
|  |  |  |  |  | S | S |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
Template Predicted Secondary structure |   |
 |  |  |
|
|  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
54 | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . |
  |
  |   |
72 | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | |
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 |
Predicted Secondary structure |   |
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . |
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
R | G | E | E | Y | I | V | G | Q | A | A | H | N | Y | L | F | E | A | G | G | A | A | V | L | G | S | I | Q | P | Q | P | I | D | A | A | A | D | G | T | L | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
P | L | D | K | V | A | M | K | I | K | P | D | D | I | H | F | A | R | T | K | L | L | S | L | E | N | T | H | N |
Query Conservation |   |
  |
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |   |
|
|   |   |   |   |   |
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |
|   |   |   |   |   |   | . |   |
|
|
|
|
|
|
|
|   |   |   |   |
Template Sequence |   |
R | P | Y | I | V | K | F | R | G | N | Y | H | G | H | A | D | G | L | L | V | E | A | G | S | G | A | L | T | L | G | V | P | S | S | A | G | V | P | E | E | Y | A | K | L | T | L | V | L | E | Y | N | D | P | E | G | L | R | E | V | L | K | R | R | G | E | E | . |
I | A | A | I | I | F | E | P | V | V | G | N | A |
Template Known Secondary structure |   |
|
|  |  |  |  |  | T | T |
|
|
|
|
|
| G | G | G | S |  |  |
|
| S | S | S |
|
| B |
|  |  | S | S | T | T |
|
|  |  |  |  | T | T |  |  |  |  |
| T | T |
|  |  |  |  |  |  |  |  |  |  |  | G | G | G | . |  |  |  |  |  |  |
| S | S | B |
| T | T |
Template Predicted Secondary structure |   |
|
|  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
| . |  |  |  |  |  |  |
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
134 | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | |
200 | . | . | . | . | . | . | . | . | . | 210 | . | . |
  |
  |   |
141 | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 |
Predicted Secondary structure |   |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
G | K | V | L | P | R | E | Y | L | K | E | A | W | E | F | T | R | E | R | N | L | A | L | H | V | D | G | A | R | I | F | N | A | V | V | A | Y | G | C | E | L | K | E | I | T | Q | Y | C | D | S | F | T | I | C | L | S | K | G | L | G | T | P | V | G | S | L | L | V | G | N | R | D | Y | I | K | R | A | I | R | W |
Query Conservation |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|   |
|
|
|   |
|
|   | . |
|   |
|   |   |   |   |   |   |   |   |
|
|   |
|
|
|   |   |   |
|
|   |
|   |   |
|   | . |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
G | V | L | V | P | T | E | D | F | L | K | A | L | H | E | A | K | A | Y | G | V | L | L | I | A | D | E | V | M | T | G | F | . |
R | L | A | F | G | G | A | T | E | L | L | G | L | K | P | D | L | V | T | L | G | K | I | L | G | G | G | L | . |
P | A | A | A | Y | A | G | R | R | E | I | M | E | K | V | A | P | L |
Template Known Secondary structure |   |
S |
| B |
|
|
|  |  |  |  |  |  |  |  |  | G | G | G | G | T |
|  |  |  |  |  |
| T | T | T | T | T | . | T | S | S | T | T |  |  |  |  |  |  | T |
|
|
| S |  |  |  |  |
| G | G | G | G | T | T | S | . | S |
|  |  |  |  |  |
|  |  |  |  | T | T | B | T | T | T |
Template Predicted Secondary structure |   |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|
|
| . |
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
| . |
|  |  |  |  |  |  |
|  |  |  |  |  |  |  |  |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
213 | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | |
. | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | |
. | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 |
  |
  |   |
221 | . | . | . | . | . | . | . | |
|
|
|
. | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | |
|
|
|
|
. | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | |
|
|
|
|
Predicted Secondary structure |   |
|
|
|
|
|
|
|
| . | . | . | . |
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . |
|
|
|  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
| . | . | . | . | . |
Query SS confidence |   |
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
Query Sequence |   |
R | K | M | T | G | G | G | M | . |
. |
. |
. |
R | Q | S | G | I | L | A | A | A | G | I | Y | A | L | K | N | N | V | A | R | L | Q | E | D | H | D | N | A | A | W | M | A | E | Q | L | R | E | . |
. |
. |
. |
. |
A | G | A | D | V | M | R | Q | D | T | N | M | L | F | V | R | V | G | E | E | N | . |
. |
. |
. |
. |
Query Conservation |   |
  |   |   |   |   |   |   |   | . | . | . | . |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   | . | . | . | . | . |
Alig confidence |   |
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
Template Conservation |   |
  |   |   |   |   |   |   |
|   |   |   |   |
|   |   |   |
|
|
|   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |
|
|
|   |
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
G | P | V | Y | Q | A | G | T | L | S | G | N | P | L | A | M | A | A | G | L | A | T | L | E | L | L | E | E | N | P | G | Y | Y | A | Y | L | E | D | L | G | A | R | L | E | A | G | L | K | E | V | L | K | E | K | G | L | P | H | T | V | N | R | V | G | S | M | I | T | V | F | F | T | E | G | P | V | V | T | F | Q |
Template Known Secondary structure |   |
S | S | B |
|
|
|
| T | T |
| S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| T |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
|
|  |  |  |  |  | T | T |  |  |  |  |  | S | S | S | S |
|
|
| S |  |  |
Template Predicted Secondary structure |   |
|
|  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
291 | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 |
  |
  |   |
|
|
|
|
|
|
|
|
|
287 | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . |
Predicted Secondary structure |   |
. | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
A | A | A | L | G | E | Y | M | K | A | R | N | V | L | I | N | A | S | P | I | V | R | L | V | T | H | L | D | V | S | R | E | Q | L | A | E | V | A | A | H | W | R | A | F | L |
Query Conservation |   |
. | . | . | . | . | . | . | . | . |   |   |   |
|   |   |   |
|   |   |   |
|
|   |
|   |   |   |   |   |
|
|   |   |   |   |   |   |   |
|   |
|
|
|   |   |   |   |   |
|   |   |   |   |
|
Alig confidence |   |
. | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|
|   |   |   |
|   |   |   |   |
|   |   |   |   |   |   |   |
|   |   |   |
|
|   |   |   |   |   |
|   |   |
|
|
Template Sequence |   |
D | A | R | R | T | D | T | E | L | F | K | R | F | F | H | G | L | L | D | R | G | I | Y | W | P | P | S | N | F | E | A | A | F | L | S | V | A | H | R | E | E | D | V | E | K | T | L | E | A | L | R | K | A | L |
Template Known Secondary structure |   |
 |  | T | T | S |
|  |  |  |  |  |  |  |  |  |  |  |  | T | T | T |  |  |
|
| S | S | S | S | S |
|  |  |
|
| T | T |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
Template Predicted Secondary structure |   |
 |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
371 | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . |
  |