|   |
2 | . | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | |
. | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | |
|
. | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
| . |
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  | . | . |
|
|
|
|  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
T | R | P | I | Q | A | S | L | D | L | Q | A | L | K | Q | N | L | S | I | V | R | Q | A | A | T | . |
H | A | R | V | W | S | V | V | K | A | N | A | Y | G | H | G | I | E | R | I | W | S | A | I | . |
. |
G | A | T | D | G | F | A | L | L | N | L | E | E | A | I | T | L | R | E | R | G | W | K | G | P | I | L | M |
Query Conservation |   |
  |
|
|
|   |
|
|
|
|
|   |
|
|   |   |
|   |   |   |
|   |   |   |   |   | . |   |   |   |
|   |   |
|
|
|
|
|
|
|
|
|
|   |   |   |
|   |   |   |
| . | . |   |
|   |   |   |
|   |
|
|   |   |   |
|
|   |   |
|
|   |   |
|   |   |   |   |
|
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|
|   |   |
|   |
|
|
|   |
|
|   |   |
|
|   |   |
|   |   |   |   |   |   |   |   |   |
|   |
|
|
|
|
|
|
|
|
|
|
|   |   |   |
|
|   |   |
|   |   |   |
|   |   |   |   |   |
|
|   |   |   |
|
|   |   |
|
|   |   |
|   |   |   |   |
|
|   |
Template Sequence |   |
H | R | P | T | R | L | H | I | D | T | Q | A | I | T | E | N | V | Q | K | E | C | Q | R | L | P | E | G | T | A | L | F | A | V | V | K | A | N | G | Y | G | H | G | A | V | E | S | A | K | A | A | K | K | G | G | A | T | G | F | C | V | A | L | L | D | E | A | I | E | L | R | E | A | G | V | Q | D | P | I | L | I |
Template Known Secondary structure |   |
T | S | S |
|  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  | T | T | S |
| T | T |
|  |  |  |  |  |
|  |  |  |  |  |  | T |
|  |  |  |  |  |  |  |  |  | T | T | T |
|
|  |  |  |  | S | S |  |  |  |  |  |  |  |  |  | T | T |
|
| S |
|  |  |  |
Template Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
6 | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . |
  |
  |   |
79 | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | |
|
|
. | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | |
. | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . |
Predicted Secondary structure |   |
 |
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  | . | . | . |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
| . |
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
L | E | G | F | F | H | A | Q | D | L | E | I | Y | D | Q | H | R | L | T | T | C | V | H | S | N | W | Q | L | K | A | L | Q | N | A | . |
. |
. |
R | L | K | A | P | L | D | I | Y | L | K | V | N | S | G | M | N | R | L | G | F | . |
Q | P | D | R | V | L | T | V | W | Q | Q | L | R | A | M | A | N | V | G | E | M |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|   |   |   |
|   |   |
|   |   |   | . | . | . |   |   |   |   |   |   |   |
|   |
|   |
|
|
|
|
|   |
|   |
|   | . |   |   |   |
|   |   |   |   |   |   |   |
|   |   |   |   |   |
|   |
|   |
Alig confidence |   |
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
| . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |
|   |
|
|
|
|
|
|
|   |
|   |
|   |   |   |   |   |
|   |   |   |   |   |   |   |
|   |   |   |   |   |
|   |
|   |
Template Sequence |   |
L | . |
S | V | V | D | L | A | Y | V | P | L | L | I | Q | Y | D | L | S | V | T | V | A | T | Q | E | W | L | E | A | A | L | Q | Q | L | T | P | E | S | N | T | P | L | R | V | H | L | K | V | D | T | G | M | G | R | I | G | F | L | T | P | E | E | T | K | Q | A | V | R | F | V | Q | S | H | K | E | F | L | W | E |
Template Known Secondary structure |   |
| . | S |
|
|
| G | G | G |  |  |  |  |  |  | T | T |
|  |  |  |  |
|
|  |  |  |  |  |  |  |  | T | T | S |
| T | T |
| S | S |
|  |  |  |  |  |  | B |
| S | S | S |
| S | S | S | B |
|
|  |  |  |  |  |  |  |  |  |  |  |  | T |
| T | T |  |  |  |  |
Template Predicted Secondary structure |   |
 | . |
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
86 | |
. | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . |
  |
  |   |
155 | . | . | . | . | 160 | . | . | . | . | . | . | . | |
|
. | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | |
|
|
. | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |
|
|
|
|
|
|
|
|
|
| . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
| . | . | . |
|
|  |  |  |  |
|
|  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
T | L | M | S | H | F | A | E | A | E | H | P | D | . |
. |
G | I | S | G | A | M | A | R | I | E | Q | A | A | E | G | L | E | . |
. |
. |
C | R | R | S | L | S | N | S | A | A | T | L | W | H | P | E | A | H | F | D | W | V | R | P | G | I | I | L | Y | G | A | S | P | S | G | Q | W | R | D | I | A | N | T | G | L |
Query Conservation |   |
|
|   |
|
|
|
|   |
|
|   |   |   | . | . |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |
|   | . | . | . |   |   |   |
|
|   |
|
|   |   |   |
|   |   |   |   |   |   |   |
|   |
|
|   |
|   |   |
|
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
Template Conservation |   |
|
|   |
|
|
|
|   |
|
|   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |
|   |   |
|
|   |   |   |
|   |   |
|   |   |   |   |
|   |
|
|   |
|
|   |
|
|
|   |   |
|   |   |   | . |   |   |   |   |   |   |   |
|
Template Sequence |   |
G | I | F | T | H | F | S | T | A | D | E | I | D | T | S | Y | F | E | K | Q | A | G | R | F | K | A | V | L | A | V | L | E | E | L | P | R | Y | V | H | V | S | N | S | A | T | A | L | W | H | P | D | V | P | G | N | M | I | R | Y | G | V | A | M | Y | G | L | N | P | S | G | N | . |
K | L | A | P | S | Y | A | L |
Template Known Secondary structure |   |
 |  |  |
|
|
| S | S | T | T | S | S |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
| S | S |
|
| S |  |  |  |  |  |
|  |  |  |  |  |  |
|
| S | S |
|
| S |  |  |  |  |
| G | G | G | G | T |
|
| T | T | T | T | . | S | S |
|
| S | S |
|
|
Template Predicted Secondary structure |   |
 |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
165 | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | |
. | . | . | . | 240 | . | . | . |
  |
  |   |
230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |
|
|
|
|  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
R | P | V | M | T | L | S | S | E | I | I | G | V | Q | T | L | K | A | G | E | R | V | G | Y | G | G | R | Y | T | A | R | D | E | Q | R | I | G | I | V | A | A | G | Y | A | D | G | Y | P | R | H | A | P | T | G | T | P | V | L | V | D | G | V | R | T | M | T | V | G | T | V | S | M | D | M | L | A | V | D | L | T |
Query Conservation |   |
  |
|
|   |   |
|   |
|   |
|   |   |
|   |   |
|   |   |
|   |   |
|
|
|
|   |   |   |   |   |   |   |   |   |   |
|
|   |
|   |
|
|
|
|
|
|   |   |
|   |   |   |   |   |   |   |
|   |
|   |
|   |   |   |
|
|
|
|   |
|   |
|
|   |   |   |
|
|
|
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|
|
|   |   |
|   |
|   |
|
|   |
|   |   |   |   |   |
|   |   |
|
|
|
|   |   |   |   |   |   |   |   |   |   |
|
|   |
|   |
|
|
|
|
|
|   |   |
|   |   |   |   |   | . |   |
|
|
|   |
|   |   |   |
|
|
|
|   |
|   |
|
|   |   |   |
|
|
|
|
Template Sequence |   |
K | P | A | L | R | L | T | S | E | L | I | H | V | K | R | L | A | A | G | E | G | I | G | Y | G | E | T | Y | V | T | E | A | E | E | W | I | G | T | V | P | I | G | Y | A | D | G | W | L | R | H | L | Q | G | F | . |
T | V | L | V | N | G | K | R | C | E | I | V | G | R | V | C | M | D | Q | C | M | I | R | L | A |
Template Known Secondary structure |   |
|
|
|  |  |  |  |  |  |
| S |
|  |  |  |  |
| T | T |
|  |  | S | G | G | G |
|  |  |
| S | S | S |  |  |  |  |  |  | S |
|
| T | T | T | T |
|
| G | G | G | T | T |
| . |  |  |  |  | T | T |  |  |  |  |  |  | S |
|
|
| S | S |
|  |  |  |  |  | S |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |
|
|
|
|  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|  |  |
|
|
|
|
|
|
|
|
|
| . |  |  |  |  |
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
244 | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | |
. | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . |
  |
  |   |
310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | |
|
|
|
. | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
| . | . | . | . |
|
|  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
P | C | P | Q | A | G | I | G | T | P | V | E | L | W | G | K | E | . |
. |
. |
. |
I | K | I | D | D | V | A | A | A | A | G | T | V | G | Y | E | L | M | C | A | L | A | L | R | V | P | V | V | T |
Query Conservation |   |
  |   |   |   |
|   |   |
|
|   |
|   |
|   |
|   |   | . | . | . | . |   |   |   |   |   |   |
|   |   |   |   |
|
|   |   |
|   |   |   |   |
|   |   |
|
|   |
|   |   |
Alig confidence |   |
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  | . | . |   |   |   |   |
|
|   |
|   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|
|   |
|
|
|
|   |   |   |   |   |
|
|   |
|   |
|
Template Sequence |   |
E | . |
. |
E | V | P | V | G | P | V | V | T | L | V | G | K | D | G | N | E | E | N | T | L | Q | M | V | A | E | K | L | E | T | I | H | Y | E | V | A | C | T | F | S | Q | R | I | P | R | E | Y |
Template Known Secondary structure |   |
S | . | . |
|
|
| S |
|
|  |  |  |  |  |  |  |  | T | T |  |  |  |
|  |  |  |  |  |  |  |  | T | S |
|  |  |  |  |  |  |  | S |
| T | T | S |
|  |  |  |
Template Predicted Secondary structure |   |
| . | . |
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
323 | |
|
. | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 |
  |