|   |
4 | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | |
|
. | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | |
. | . | . | . | . | . | 80 |
Predicted Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  | . | . |
|
|
|
|  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |
|
|
|
| . |
|  |  |  |  |  |
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
Query Sequence |   |
P | I | Q | A | S | L | D | L | Q | A | L | K | Q | N | L | S | I | V | R | Q | A | A | T | H | A | R | V | W | S | V | V | K | A | N | A | Y | G | H | G | I | E | R | I | W | S | A | I | . |
. |
G | A | T | D | G | F | A | L | L | N | L | E | E | A | I | T | L | R | E | R | G | W | K | . |
G | P | I | L | M | L | E |
Query Conservation |   |
|
|   |
|
|
|
|
|   |
|
|   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |
|   |   |
|
|
|
|
|
|
|
|
|
|   |   |   |
|   |   |   |
| . | . |   |
|   |   |   |
|   |
|
|   |   |   |
|
|   |   |
|
|   |   |
|   |   | . |   |   |
|
|   |   |   |
Alig confidence |   |
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
| . | . |
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
Template Conservation |   |
|   |
|
| . |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |   |   |
|
|
|
|
|
|   | . | . | . | . |   |   |   |
|
|   |   |
|   |   |   |
|   | . |
|   |
|
|   |
|   |   |
|
|   |   |
|   |   |   |
|   |   |   |   |   |
|
|   |   |
|
Template Sequence |   |
A | F | F | V | . |
G | D | L | G | K | I | V | K | K | H | S | Q | W | Q | T | V | V | A | Q | I | K | P | F | Y | T | V | K | C | N | S | . |
. |
. |
. |
T | P | A | V | L | E | I | L | A | A | L | G | T | . |
G | F | A | C | S | S | K | N | E | M | A | L | V | Q | E | L | G | V | S | P | E | N | I | I | F | T | S |
Template Known Secondary structure |   |
|  |  |  | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| T | T |  |  |  |  |  |  | G | G | G |
|
| . | . | . | . |
|  |  |  |  |  |  |  |  |  |  | T |
| . |  |  |  |  | S | S |  |  |  |  |  |  |  |  |  | T | T |
|
| G | G | G |  |  |  |
|
|
Template Predicted Secondary structure |   |
 |  |  |  | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |
|
| . | . | . | . |
|  |  |  |  |  |  |  |  |  |
|
|
| . |
|  |  |  |
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
39 | 40 | . | . | |
. | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | |
|
|
|
. | . | . | . | . | . | . | 80 | . | . | . | . | . | |
. | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . |
  |
  |   |
81 | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | |
. | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
| . |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
G | F | F | H | A | Q | D | L | E | I | Y | D | Q | H | R | L | . |
T | T | C | V | H | S | N | W | Q | L | K | A | L | Q | N | A | R | L | K | A | P | L | D | I | Y | L | K | V | N | S | G | M | N | R | L | G | F | Q | P | D | R | V | L | T | V | W | Q | Q | L | R | A | M | A | N | V | G | E | M | T | L | M | S | H |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . |   |   |   |
|
|
|   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |
|   |
|
|
|
|
|   |
|   |
|   |   |   |   |
|   |   |   |   |   |   |   |
|   |   |   |   |   |
|   |
|   |
|
|   |
|
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |
|   |   |   |   |
|   |   |
|
|   |   |
|
|   |   |
|   |   |
|
|   |   |
|
|   |   |
|   |   |   |   |
|   |   | . | . |   |
|   |
|
|
|   |   |   |   |
|
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   | . |   |   |
|   |
|   |
|
|
|   |
|
Template Sequence |   |
P | C | K | Q | V | S | Q | I | K | Y | A | A | K | V | G | V | N | I | M | T | C | D | N | E | I | E | L | K | K | I | A | R | N | H | P | N | A | . |
. |
K | V | L | L | H | I | A | T | E | D | M | K | F | G | T | T | L | K | N | C | R | H | L | L | E | C | A | K | E | . |
L | D | V | Q | I | I | G | V | K | F | H |
Template Known Secondary structure |   |
S | S |
|
|  |  |  |  |  |  |  |  |  |  | T |
|
|  |  |  |  |
| S |  |  |  |  |  |  |  |  |  |  |
| T | T |
| . | . |  |  |  |  |  | B |
|
|
|
|
|
|
|
| B |
|  |  |  |  |  |  |  |  |  |  |  |  |  | . |  | T |
|  |  |  |  |  |  |
|
|
Template Predicted Secondary structure |   |
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
| . | . |
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  | . |
|
|
|  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
113 | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | |
|
150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | |
. | 180 | . | . | . | . | . | . | . | . | . |
  |
  |   |
160 | . | . | . | . | |
. | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | |
|
|
. | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | 210 | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
| . |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . |  |  |
|
|
|
|  |  |  |  |
|
|  |  |  |  |
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
Query Sequence |   |
F | A | E | A | E | . |
H | P | D | G | I | S | G | A | M | A | R | I | E | Q | A | A | . |
. |
. |
E | G | L | E | C | R | R | S | L | S | N | S | A | A | T | L | W | H | P | E | A | H | F | D | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
W | V | R | P | G | I | I | L | Y |
Query Conservation |   |
|
|   |
|
| . |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   | . | . | . |   |   |
|   |   |   |   |
|
|   |
|
|   |   |   |
|   |   |   |   |   |   |   |
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |
|
|   |
|   |   |
|
|
Alig confidence |   |
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |
|   |   |   |   |   |   |   |
|   |   |   |   |   |
|
|
|
|
|
|   |   |   |   |   |   |   |   |
|   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|
|
|   |
|
|
Template Sequence |   |
V | S | S | A | C | K | E | Y | Q | V | Y | V | H | A | L | S | D | A | R | C | V | F | D | M | A | G | E | F | G | F | T | M | N | M | L | D | I | G | G | G | F | T | G | T | E | I | Q | L | E | E | V | N | H | V | I | S | P | L | L | D | I | Y | F | P | E | G | S | G | I | Q | I | I | S | E | P | G | S | Y | Y | V |
Template Known Secondary structure |   |
|
| T | T |
|
|
| T | T |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
|
|
|  |  |  |
|
| S |
|
|
| S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | S |
| T | T | S |
|
|  |  |  |  |
|
| S |  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |
|
|
|  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
198 | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . |
  |
  |   |
214 | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |
|
|
|
|  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
G | A | S | P | S | G | Q | W | R | D | I | A | N | T | G | L | R | P | V | M | T | L | S | S | E | I | I | G | V | Q | T | L | K | A | G | E | R | V | G | Y | G | G | R | Y | T | A | R | D | E | Q | R | I | G | I | V | A | A | G | Y | A | D | G | Y | P | R | H | A | P | T | G | T | P | V | L | V | D | G | V | R | T |
Query Conservation |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|   |   |
|   |
|   |
|   |   |
|   |   |
|   |   |
|   |   |
|
|
|
|   |   |   |   |   |   |   |   |   |   |
|
|   |
|   |
|
|
|
|
|
|   |   |
|   |   |   |   |   |   |   |
|   |
|   |
|   |   |   |
Alig confidence |   |
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |
|
|   |
|
|
|   |
|   |   |   |
|   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
S | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
S | A | F | T | L | A | V | N | I | I | A | K | K | V | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
V | A | F | V | Y | Y | M | N | D | G | V | Y | G | S | F | A | S | K | L | S | T | I | P | E | V | H | K | K | P | L | F | T | S |
Template Known Secondary structure |   |
T | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | T | T |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|  |  |  |  |  | S |
|
| T | T | T | T | T | G | G | G | G |
|
|
|
|  |  |
|
|
|
|  |  |  |  |
Template Predicted Secondary structure |   |
 | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
278 | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . |
  |
  |   |
294 | . | . | . | . | . | 300 | . | |
|
. | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . |
Predicted Secondary structure |   |
 |  |  |
|
|
|
|
| . | . |
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
M | T | V | G | T | V | S | M | . |
. |
D | M | L | A | V | D | L | T | P | C | P | Q | A | G | I | G | T | P | V | E | L |
Query Conservation |   |
|
|
|
|   |
|   |
| . | . |
|   |   |   |
|
|
|
|   |   |   |   |
|   |   |
|
|   |
|   |
|
Alig confidence |   |
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|   |
|   |   |
|   |   |   |
|   |
|   |   |   |   |   | . |
|
|   |
|   |   |
|
|   |
|   |
|
Template Sequence |   |
S | L | W | G | P | S | C | D | E | L | D | Q | I | V | E | S | C | L | . |
L | P | E | L | N | V | G | D | W | L | I | F |
Template Known Secondary structure |   |
 |  |  |
| T | T |
| S | T | T |
|  |  |  |  |  |  |  | . |  |  |
|
|
| T | T |
|  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  | . |
|
|
|
|
|
|
|
|  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
352 | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | |
370 | . | . | . | . | . | . | . | . | . | 380 | . |
  |