|   |
3 | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
. | . | . | . | 30 | . | . | . | . | . | . | |
. | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
Predicted Secondary structure |   |
 |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  | . |  |
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Query Sequence |   |
N | I | W | W | Q | T | K | G | Q | G | N | V | H | L | V | L | L | H | G | W | G | L | N | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
A | E | V | W | R | C | I | D | E | E | L | . |
S | S | H | F | T | L | H | L | V | D | L | P | G | F | G | R | S | R | G | F | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Query Conservation |   |
  |
|   |
|   |   |   |
|   |
|   |
|   |
|
|
|
|
|
|   |   |   |   | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |
| . |   |   |   |   |   |
|
|   |   |
|   |   |
|   |
|   |
|   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Conservation |   |
  |
|   |   |
|   |   |   |   |   |   |
|   |
|
|   |   |   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|
|
|
|   |   |
|   |
|
|   |
|   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
V | I | V | L | P | K | G | A | K | N | A | P | I | V | L | T | R | T | P | Y | D | A | S | G | R | T | E | R | L | A | S | P | H | X | K | D | L | L | S | A | G | D | D | V | F | V | E | G | G | Y | I | R | V | F | Q | D | V | R | G | K | Y | G | S | E | G | D | Y | V | X | T | R | P | L | R | G | P | L | N | P | S |
Template Known Secondary structure |   |
 |  |  |  |  | T | T |
|
| S |  |  |  |  |  |  |  |  | S | S |
|  |  |  |  | T |
| S | S |
|
| S |
|  |  |  |  | S |
| G | G | G |  |  |  |  |  | T | T |
|  |  |  |  |  |  |
| T | T | S | T | T |
|
| S |
|
|
| T | T |
|
|
| S | B | T | T | B |
| S |
Template Predicted Secondary structure |   |
 |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |
|
|
|
|
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
63 | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . |
  |
  |   |
|
|
|
|
|
|
57 | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 |
Predicted Secondary structure |   |
. | . | . | . | . | . |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
. |
. |
. |
. |
. |
. |
G | A | L | S | L | A | D | M | A | E | A | V | L | Q | Q | A | P | D | K | A | I | W | L | G | W | S | L | G | G | L | V | A | S | Q | I | A | L | T | H | P | E | R | V | Q | A | L | V | T | V | A | S | S | P | C | F | S | A | R | D | E | W | P | G | I | K | P | D | V | L | A | G | F | Q | Q |
Query Conservation |   |
. | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
. | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |
|   |   |
|   |   |
|   |
|   |
|   |   |   |
|   |   |
|
|   |
|
|
|
|
|   |
|   |
|
|
|
|   |   |   |   |   |   |
|   |   |   |   |
|   |
|
|
|
|
|
|   |   |   |   |   |
|   |
|   |   |   |   |   |   |   |
|
|   |   |   |   |   |   |   |   |   |
Template Sequence |   |
E | V | D | H | A | T | D | A | W | D | T | I | D | W | L | V | K | N | V | S | E | S | N | G | K | V | G | X | I | G | S | S | Y | E | G | F | T | V | V | X | A | L | T | N | P | H | P | A | L | K | V | A | V | P | E | S | P | X | I | D | G | W | X | G | D | D | W | F | N | Y | G | A | F | R | Q | V | N | F | D | Y |
Template Known Secondary structure |   |
S |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| T | T |  |  |  |  |  |  |  |  |  |  | T |  |  |  |  |  |  |  |  |  |  | T | S |
|
| T | T |  |  |  |  |  |  |  | S |
|
|
|
| T | T | T | T | S | S | S |  |  | T | T |  |  | B | G | G | G |  |  |  |
Template Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
143 | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . |
  |
  |   |
131 | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | |
|
|
|
|
|
|
|
. | . | . | . | . | . | . | . | . | 200 | . | . |
Predicted Secondary structure |   |
 |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
Q | L | S | D | D | F | Q | R | T | V | E | R | F | L | A | L | Q | T | M | G | T | E | T | A | R | Q | D | A | R | A | L | K | K | T | V | L | A | L | P | M | P | E | V | D | V | L | N | G | G | L | E | I | L | K | T | V | D | L | R | Q | . |
. |
. |
. |
. |
. |
. |
. |
P | L | Q | N | V | S | M | P | F | L | R | L |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |
|   |
|   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|   |
|   |
|
Template Sequence |   |
F | T | G | Q | L | S | K | R | G | K | G | A | G | I | A | R | Q | G | H | D | D | Y | S | N | F | L | Q | A | G | S | A | G | D | F | A | K | A | A | G | L | E | Q | L | P | W | W | H | K | L | T | E | H | A | A | Y | D | A | F | W | Q | E | Q | A | L | D | K | V | X | A | R | T | P | L | K | V | P | T | X | W | L |
Template Known Secondary structure |   |
 |  |  |  |  | S | S | S | S |
|
|
|
|
|
|
| S | S | S |
|  |  |  |  |  |  |  |  |
| S |  |  |  |  |  |  |  | T | T | G | G | G | S |  |  |  |  |  |  |  |  | T |
| S | S |
|  |  |  |  | T | T |
|  |  |  |  |  |  | T | S |
|
|
| S |
|  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
223 | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . |
  |
  |   |
203 | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | |
|
|
|
|
. | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | . | 250 | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  | . | . | . | . | . |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |
| . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
Y | G | Y | L | D | G | L | V | P | R | K | V | V | P | M | L | . |
. |
. |
. |
. |
D | K | L | W | P | H | S | E | S | Y | I | F | A | K | A | A | H | A | P | F | I | S | H | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
P | A | E | F | C | H | L | L | V | A | L | K | Q | R |
Query Conservation |   |
  |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|
|   |   |   |   |
|   | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|   |   |   |   |   |   |
|   |   |
|
|   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|   |
Template Sequence |   |
Q | G | L | W | D | Q | E | D | X | W | G | A | I | H | S | Y | A | A | X | E | P | R | D | K | R | N | T | L | N | Y | L | V | X | G | P | W | R | H | S | Q | V | N | Y | D | G | S | A | L | G | A | L | N | F | E | G | D | T | A | R | Q | F | R | H | D | V | L | R | P | F | F | D | Q |
Template Known Secondary structure |   |
 |  | T | T |
| S | S |
| S | S |  |  |  |  |  |  |  |  |  | G | G | G |
| T | T | S | S | S |  |  |  |  |  |  | S |
| S | T | T | G | G | G | S |
|
| S |  |  | T | T |  |  |
| S | S |
|  |  |  |  |  |  |  |  | T |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
303 | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . |
  |