Job Description P39305 Confidence 96.13% Date Thu Jan 5 11:59:09 GMT 2012 Rank 52 Aligned Residues 231 % Identity 12% Template c2cw6B_ PDB info PDB header:lyase Chain: B: PDB Molecule:hydroxymethylglutaryl-coa lyase, mitochondrial; PDBTitle: crystal structure of human hmg-coa lyase: insights into2 catalysis and the molecular basis for3 hydroxymethylglutaric aciduria Resolution 2.10 Å

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		2	.	.	.	.	.	.	.	10	.						.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.				.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.
Predicted Secondary structure												.	.	.	.	.																					.	.	.																												.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query SS confidence												.	.	.	.	.																					.	.	.																												.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Sequence		L	S	K	Q	I	P	L	G	I	Y	.	.	.	.	.	E	K	A	L	P	A	G	E	C	W	L	E	R	L	Q	L	A	K	T	L	.	.	.	G	F	D	F	V	E	M	S	V	D	E	T	D	D	R	L	S	R	L	N	W	S	R	E	Q	R	L	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Conservation												.	.	.	.	.																					.	.	.																												.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Alig confidence												.	.	.	.	.																					.	.	.																												.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation
Template Sequence		L	P	K	R	V	K	I	V	E	V	G	P	R	D	G	L	Q	N	E	K	N	I	V	S	T	P	V	K	I	K	L	I	D	M	L	S	E	A	G	L	S	V	I	E	T	T	S	F	V	S	P	K	W	V	P	Q	M	G	D	H	T	E	V	L	K	G	I	Q	K	F	P	G	I	N	Y	P	V	L	T	P
Template Known Secondary structure				S	B							T	T	T					T		S	S																	T	T		S										T	T	T		G	G	G	T	T								S				T	T		B
Template Predicted Secondary structure
Template SS confidence
		29	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.
				59	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.								.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.
Predicted Secondary structure		.	.																																						.	.	.	.	.	.	.
Query SS confidence		.	.																																						.	.	.	.	.	.	.
Query Sequence		.	.	A	L	V	N	A	I	V	E	T	G	V	R	V	P	S	M	C	L	S	A	H	R	R	F	P	L	G	S	E	D	D	A	V	R	A	Q	G	.	.	.	.	.	.	.	L	E	I	M	R	K	A	I	Q	F	A	Q	D	V	G	I	R	V	I	Q	L	A	G	Y	D	V	Y	Y	Q	E	A	N	N	E
Query Conservation		.	.																																						.	.	.	.	.	.	.
Alig confidence		.	.																						.	.	.	.	.	.	.	.									.	.	.	.	.	.	.
Template Conservation																									.	.	.	.	.	.	.	.
Template Sequence		N	L	K	G	F	E	A	A	V	A	A	G	A	K	E	V	V	I	F	G	A	A	S	.	.	.	.	.	.	.	.	E	L	F	T	K	K	N	I	N	C	S	I	E	E	S	F	Q	R	F	D	A	I	L	K	A	A	Q	S	A	N	I	S	V	R	G	Y	V	S	C	A	L	G	C	P	Y	E	G	K	I
Template Known Secondary structure		S										T	T		S								S		.	.	.	.	.	.	.	.								T	S	S		T	T	T															T	T									S	T	T		B	T	T	T	B	S
Template Predicted Secondary structure																									.	.	.	.	.	.	.	.
Template SS confidence
		109	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.									.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
		130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		T	R	R	R	F	R	D	G	L	K	E	S	V	E	M	A	S	R	A	Q	V	T	L	A	M	E	I	M	D	Y	P	L	M	S	S	I	S	K	A	L	G	Y	A	H	Y	L	N	N	P	W	F	Q	L	Y	P	D	I	G	N	L	S	A	W	D	N	D	V	Q	M	E	L	Q	A	G	I	G	H	I	V	A
Query Conservation
Alig confidence				.	.	.	.																		.
Template Conservation				.	.	.	.																		.
Template Sequence		S	P	.	.	.	.	A	K	V	A	E	V	T	K	K	F	Y	S	M	G	C	Y	E	.	I	S	L	G	D	T	I	G	V	G	T	P	G	I	M	K	D	M	L	S	A	V	M	Q	E	V	P	L	A	A	L	A	V	H	C	H	D	T	Y	G	Q	A	L	A	N	T	L	M	A	L	Q	M	G	V	S	V
Template Known Secondary structure				.	.	.	.													T	T		S		.						T	T																			S		G	G	G						B		T	T	S												T	T
Template Predicted Secondary structure				.	.	.	.																		.
Template SS confidence
		181	.					.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.		200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.
		210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		V	H	V	K	D	T	K	P	G	V	F	K	N	V	P	F	G	E	G	V	V	D	F	E	R	C	F	E	T	L	K	Q	S	G	Y	C
Query Conservation
Alig confidence
Template Conservation
Template Sequence		V	D	S	S	V	A	G	L	G	G	C	P	Y	A	Q	G	A	S	G	N	L	A	T	E	D	L	V	Y	M	L	E	G	L	G	I	H
Template Known Secondary structure					B	T	T	S					T	T	S	S	S				B		B											T	T		B
Template Predicted Secondary structure
Template SS confidence
		256	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.

No model constructed - rank, confidence too low

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Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions