|   |
199 | 200 | . | . | . | . | . | . | . | . | . | 210 | . | |
|
|
|
|
|
|
. | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |
|
|
|
| . | . | . | . | . | . | . |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
E | A | E | Q | Y | I | A | R | V | F | N | A | D | . |
. |
. |
. |
. |
. |
. |
R | S | Y | M | V | T | N | G | T | S | T | A | N | K | I | V | G | M | Y | S | A | P | A | G | S | T | I | L | I | D | R | N | C | H | K | S | L | T | H | L | M | M | M | S | D | V | T | P | I | Y | F | R | P | T | R | N | A | Y | G | I |
Query Conservation |   |
|
|
|   |
|
|
|   |   |
|
|
|   | . | . | . | . | . | . | . |   |
|   |
|
|
|
|
|
|
|   |
|
|   |
|   |
|   |
|   |   |   |   |
|
|   |
|
|
|   |
|
|
|
|
|
|
|   |   |
|
|   |
|
|
|
|   |
|
|
|
|   |
|   |   |   |   |   |
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|
|   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |
|   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |
|
|   |
|
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
E | F | L | A | A | I | A | H | W | F | S | T | Q | H | Y | T | A | I | D | S | Q | T | V | V | Y | G | P | S | V | I | Y | M | V | S | E | L | I | R | Q | W | S | E | T | G | E | G | V | V | I | H | T | P | A | Y | D | A | F | Y | K | A | I | E | G | N | Q | R | T | V | M | P | V | A | L | E | K | Q | A | D | G | W |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  | S |
|
|
|
|
| G | G | G |  |  |  |  | S |
|  |  |  |  |  |  |  |  |  |  |  | S | S |
| T | T |
|  |  |  |  |  |  | S |
|
|  |  |  |  |  |  |  |  |  | T | T |
|  |  |  |  |  |  |
|  |  |
| S | S | S |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
68 | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . |
  |
  |   |
272 | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | |
|
|
|
. | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | |
|
. | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
| . | . | . | . |
|
|
|  |  |  |  |  |  |  |  |
|
|
|
| . | . |  |  |  |  |
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
L | G | G | I | P | Q | S | E | F | Q | H | A | T | I | A | K | R | V | K | E | T | P | N | A | T | W | P | V | H | A | V | I | T | N | S | T | Y | D | G | L | . |
. |
. |
. |
L | Y | N | T | D | F | I | K | K | T | L | D | V | K | S | . |
. |
I | H | F | D | S | A | W | V | P | Y | T | N | F | S | P | I | Y | E | G |
Query Conservation |   |
  |
|   |
|   |   |   |   |
|   |   |   |   |
|   |   |
|
|   |   |   |
|   |
|   |   |
|   |   |   |
|
|
|
|
|
|
|   |
|
| . | . | . | . |   |   |
|
|   |   |
|   |
|   |   |
|   |   |   | . | . |
|
|
|
|
|
|
|
|
|
|   |   |
|
|
|   |   |   |   |
Alig confidence |   |
| . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
Template Conservation |   |
  | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |
|
|   |
|   |   |   |   |   |   |   | . | . | . | . | . |   |   |   |
Template Sequence |   |
F | . |
. |
. |
. |
. |
. |
. |
C | D | M | G | K | L | E | A | V | L | A | K | P | E | C | . |
. |
. |
. |
K | I | M | L | L | C | S | P | Q | N | P | T | G | K | V | W | T | C | D | E | L | E | I | M | A | D | L | C | E | R | H | G | V | R | V | I | S | D | E | I | H | M | D | M | V | . |
. |
. |
. |
. |
W | G | E |
Template Known Secondary structure |   |
 | . | . | . | . | . | . | . |
|
|  |  |  |  |  |  |  |  | T | S | T | T |  | . | . | . | . |  |  |  |  |  |  | S | S |
| T | T | T |
|
|
|
|
| T | T |  |  |  |  |  |  |  |  |  |  |  | T | T |
|  |  |  |  |  |
| T | T | T | T |
| B | . | . | . | . | . |
| S | S |
Template Predicted Secondary structure |   |
| . | . | . | . | . | . | . |
|
|  |  |  |  |  |  |  |
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
148 | |
|
|
|
|
|
|
. | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | |
|
|
|
. | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | |
|
|
|
|
. | 210 | . |
  |
  |   |
346 | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | |
|
. | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|
| . | . |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
K | C | G | M | S | G | G | R | V | E | G | K | V | I | Y | E | T | Q | S | T | H | K | L | . |
. |
L | A | A | F | S | Q | A | S | M | I | H | V | K | G | D | V | N | E | E | T | F | N | E | A | Y | M | M | H | T | T | T | S | P | H | Y | G | I | V | A | S | T | E | T | A | A | A | M | M | K | G | N | A | G | K | R |
Query Conservation |   |
  |   |   |
|
|   |   |
|
|   |   |
|
|
|   |
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|   |
|   |
|
|
|   |   |   |
|   |   |   |   |   |   |   |
|
|   |   |   |
|
|
|
|
|
|
|   |
|
|
|
|
|
|   |
|
|   |   |
|   |   |
|   |
|   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|   |   |   |   |   |
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   | . |   |   |   |
Template Sequence |   |
Q | P | H | I | P | W | S | N | V | A | R | G | D | W | A | L | L | T | S | G | S | K | S | F | N | I | P | A | L | T | G | A | Y | G | I | I | E | N | S | S | S | R | D | A | Y | L | S | A | L | K | G | R | D | G | L | S | S | P | S | V | L | A | L | T | A | H | I | A | A | Y | Q | Q | G | A | P | W | . |
L | D | A |
Template Known Secondary structure |   |
S |
|
|
|
| G | G | G | T |
|
| S | S |  |  |  |  |  |
| S |  |  |  |  | T |
| G | G | G |
|
|  |  |  |  |  |
| S |  |  |  |  |  |  |  |  |  |  |  |  | T | T | S |
|
|
| S |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|  |  |  | . |  |  |  |
Template Predicted Secondary structure |   |
|
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |
|  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  | . |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
212 | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | |
. | . | 290 |
  |
  |   |
424 | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480 | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
L | I | N | G | S | I | E | R | A | I | K | F | R | K | E | I | K | R | L | R | T | E | S | D | G | W | F | F | D | V | W | Q | P | D | H | I | D | T | T | E | C | W | P | L | R | S | D | S | T | W | H | G | F | K | N | I | D | N | E | H | M | Y | L | D | P | I | K | V | T | L | L | T | P | G | M | E | K | D | G | T |
Query Conservation |   |
|   |   |   |   |
|   |   |
|   |   |
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|
|
|   |
|
|   |
|   |   |   |   |   |
|   |   |
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |
Template Sequence |   |
L | R | I | Y | L | K | D | N | L | T | Y | I | A | D | K | M | N | A | A | F | P | E | L | N | W | Q | I | P | Q | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
S | T | Y | L | A | W | L | D | L | R | P | L | N | I | D | D | N |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| S | S |
|
|
|
|
|
| S | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | B |
| S |  |  |  |  |  |
| G | G | G |
|
|
|  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
291 | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . |
  |
  |   |
504 | . | . | . | . | . | 510 | . | . | . | . | . | . | . | . | . | 520 | . | . | . | . | . | . | . | . | . | 530 | . | . | . | |
|
|
|
. | . | . | . | . | . | 540 | . | . | . | . | . | . | . | . | . | 550 | . | . | . | . | . | . | . | . | . | 560 |
Predicted Secondary structure |   |
 |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
|
|
|
|  |  | . | . | . | . |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
M | S | D | F | G | I | P | A | S | I | V | A | K | Y | L | D | E | H | G | I | V | V | E | K | T | G | P | Y | N | L | . |
. |
. |
. |
L | F | L | F | S | I | G | I | D | K | T | K | A | L | S | L | L | R | A | L | T | D | F | K | R | A | F |
Query Conservation |   |
  |   |   |   |
|
|   |
|   |   |
|   |   |
|
|   |   |   |
|
|   |   |
|   |   |   |   |   |   |
| . | . | . | . |
|   |
|   |
|
|
|   |
|   |   |   |   |   |   |
|   |   |
|
|   |   |
|   |   |   |   |
Alig confidence |   |
| . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  | . | . | . | . | . | . | . | . |   |   |   |   |
|   |   |   |   |
|
|   |
|   |
|
|   |   |
|   |   |   |   |   |   |   |
|
|
|
|   |   |   |   |   |   |   |
|   |   |
|
|   |   |
|   |   |
|
|   |   |   |
Template Sequence |   |
A | . |
. |
. |
. |
. |
. |
. |
. |
L | Q | K | A | L | I | E | Q | E | K | V | A | I | M | P | G | Y | T | Y | G | E | E | G | R | G | F | V | R | L | N | A | G | C | P | R | S | K | L | E | K | G | V | A | G | L | I | N | A | I | R | A | V |
Template Known Secondary structure |   |
 | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  | T | T |
|  |  |
|  |  | G | G | G | G |
| G | G | G | T | T |  |  |  |  |  |
|
| S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |
|  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
337 | |
|
|
|
|
|
|
|
. | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . |
  |