|   |
193 | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | |
|
|
|
|
|
|
|
. | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . |
Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . |
|
|
|
|
|  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
H | S | G | P | H | K | E | A | E | Q | Y | I | A | R | V | F | N | A | D | R | S | Y | M | V | T | N | G | T | S | T | A | N | K | I | V | G | M | Y | S | . |
. |
. |
. |
. |
. |
. |
. |
A | P | A | G | S | T | I | L | I | D | R | N | C | H | K | S | L | T | H | L | M | M | M | S | D | V | T | P | I | Y | F | R | P |
Query Conservation |   |
|   |
|   |
|   |
|
|
|   |
|
|
|   |   |
|
|
|   |   |
|   |
|
|
|
|
|
|
|   |
|
|   |
|   |
|   |
|   | . | . | . | . | . | . | . | . |   |   |   |
|
|   |
|
|
|   |
|
|
|
|
|
|
|   |   |
|
|   |
|
|
|
|   |
|
|
|
|   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |
|   |   |   |   |   |   |   |   |
|
| . |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
Y | N | E | N | I | A | A | A | A | K | N | L | A | K | A | S | A | L | E | R | V | F | F | T | N | S | G | . |
T | E | S | I | E | G | A | X | K | T | A | R | K | Y | A | F | N | K | G | V | K | G | G | Q | F | I | A | F | K | H | S | F | H | G | R | T | L | G | A | L | S | L | T | A | N | E | K | Y | Q | K | P | F |
Template Known Secondary structure |   |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
| S |  |  |  |  |  | S | S |  | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
| T | T |
|  |  |  |  |  | T | T |
|
|
|
| S | S |  |  |  |  | T | T |
|
|
|  |  |  |  | G | G | G |
Template Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|  | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
76 | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | |
. | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . |
  |
  |   |
265 | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | |
|
|
. | . | . | . | . | 320 | . | . | |
|
. | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
| . | . | . |  |  |  |  |  |  |  |  | . | . |
|
|
|
|  |  |  |  |
|
|
|  |  |  |
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
T | R | N | A | Y | G | I | L | G | G | I | P | Q | S | E | F | Q | H | A | T | I | A | K | R | V | K | E | T | P | N | A | T | W | P | V | H | A | V | I | T | N | S | T | Y | D | G | L | L | Y | N | . |
. |
. |
T | D | F | I | K | K | T | L | . |
. |
D | V | K | S | I | H | F | D | S | A | W | V | P | Y | T | N | F |
Query Conservation |   |
  |   |   |   |   |
|   |   |
|   |
|   |   |   |   |
|   |   |   |   |
|   |   |
|
|   |   |   |
|   |
|   |   |
|   |   |   |
|
|
|
|
|
|
|   |
|
|   |   |
| . | . | . |
|   |   |
|   |
|   |   | . | . |
|   |   |   |
|
|
|
|
|
|
|
|
|
|   |   |
|
Alig confidence |   |
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   | . | . | . | . | . | . |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |
|   |   |
|   |   |
|   |   |   |   |
|   |   |
|
|   |
|
|   |   |   |
|   |   |   |   |
Template Sequence |   |
K | P | L | I | S | G | V | K | . |
. |
. |
. |
. |
. |
F | A | K | Y | N | D | I | S | S | V | E | K | L | V | N | E | K | T | C | A | I | I | L | E | S | V | Q | G | E | G | G | I | N | P | A | N | K | D | F | Y | K | A | L | R | K | L | C | D | E | K | D | I | L | L | I | A | D | E | I | Q | C | G | X | G | R | S |
Template Known Secondary structure |   |
| S |
|
| S |
|  |  | . | . | . | . | . | . |  |  |
| T | T |
|  |  |  |  |  | T | T |
|
| T | T |  |  |  |  |  |  |  | S |  |  |
| T | T | S |
|  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
|  |  |  |  |  |
| T | T | T | T | T | T | T | T |
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|  | . | . | . | . | . | . |  |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
155 | . | . | . | . | 160 | . | . | |
|
|
|
|
|
. | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . |
  |
  |   |
340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
S | P | I | Y | E | G | K | C | G | M | S | G | G | R | V | E | G | K | V | I | Y | E | T | Q | S | T | H | K | L | L | A | A | F | S | Q | A | S | M | I | H | V | K | G | D | V | N | E | E | T | F | N | E | A | Y | M | M | H | T | T | T | S | P | H | Y | G | I | V | A | S | T | E | T | A | A | A | M | M | K | G | N |
Query Conservation |   |
|
|   |   |   |   |   |   |   |
|
|   |   |
|
|   |   |
|
|
|   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |
|   |
|
|
|   |   |   |
|   |   |   |   |   |   |   |
|
|   |   |   |
|
|
|
|
|
|
|   |
|
|
|
|
|
|   |
|
|   |   |
|   |   |
|
Alig confidence |   |
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |   | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |
|   |   | . | . |
|   |
|
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   | . |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |
|
|   |   |
|   |   |   |   |   |   |   |   |
Template Sequence |   |
G | K | F | . |
. |
. |
. |
. |
. |
F | A | Y | E | H | A | Q | I | L | P | D | I | X | . |
. |
T | S | A | K | A | L | G | C | G | L | S | V | G | A | F | V | I | N | Q | K | V | . |
A | S | N | S | L | E | A | G | D | H | G | S | T | Y | G | G | N | P | L | V | C | A | G | V | N | A | V | F | E | I | F | K | E | E |
Template Known Secondary structure |   |
S | S | S | . | . | . | . | . | . | S | G | G | G | G | G | T |
|
|
| S |  |  | . | . |  |  |
| G | G | G | T | T | T | S |
|
|  |  |  |  |  |
|  |  |  | . |  |  |  |  | S |
| T | T |
|
| S | S |
| B | S |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
Template Predicted Secondary structure |   |
|
|
| . | . | . | . | . | . |
|  |  |  |  |  |
|
|
|
|  |  |  | . | . |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |
|  |  |  | . |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
229 | 230 | . | |
|
|
|
|
|
. | . | . | . | . | . | . | . | 240 | . | . | . | . | |
|
. | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | |
. | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . |
  |
  |   |
420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480 | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | G | K | R | L | I | N | G | S | I | E | R | A | I | K | F | R | K | E | I | K | R | L | R | T | E | S | D | G | W | F | F | D | V | W | Q | P | D | H | I | D | T | T | E | C | W | P | L | R | S | D | S | T | W | H | G | F | K | N | I | D | N | E | H | M | Y | L | D | P | I | K | V | T | L | L | T | P | G | M | E |
Query Conservation |   |
  |
|   |   |
|   |   |   |   |
|   |   |
|   |   |
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|
|
|   |
|
|   |
|   |   |   |   |   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |
|
Template Sequence |   |
K | I | L | E | N | V | N | K | L | T | P | Y | L | E | Q | S | L | D | E | L | I | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
N | E | F | D | F | C | K | K | R | K | G | L | G |
Template Known Secondary structure |   |
T |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |
| T | T |  |  |  |  |  |  |  | T |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |
|
|
|
|  |  |
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | . | . | 330 | . | . | . |
  |
  |   |
500 | |
. | . | . | . | . | . | . | . | . | 510 | . | . | . | . | . | . | . | . | . | 520 | . | . | . | . | . | . | . | . | . | 530 | . | . | . | . | . | . | . | . | . | 540 | . | . | . | . | . | . | . | . | . | 550 | . | . | . | . | . | . | . | . | . | 560 |
Predicted Secondary structure |   |
| . |
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
K | . |
D | G | T | M | S | D | F | G | I | P | A | S | I | V | A | K | Y | L | D | E | H | G | I | V | V | E | K | T | G | P | Y | N | L | L | F | L | F | S | I | G | I | D | K | T | K | A | L | S | L | L | R | A | L | T | D | F | K | R | A | F |
Query Conservation |   |
  | . |   |
|   |   |   |   |   |
|
|   |
|   |   |
|   |   |
|
|   |   |   |
|
|   |   |
|   |   |   |   |   |   |
|
|   |
|   |
|
|
|   |
|   |   |   |   |   |   |
|   |   |
|
|   |   |
|   |   |   |   |
Alig confidence |   |
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|
|   |
|   |   |   |
|   |   |   |
|
|   |   |   |   |   |   |   |
|   |
|   |
|
|   |   |   |   |   |
|   |   |   |
|   |   |   |
Template Sequence |   |
F | X | Q | G | L | S | L | D | K | S | V | K | V | A | K | V | I | Q | K | C | Q | E | N | A | L | L | L | I | S | C | G | E | N | D | L | R | F | L | P | P | L | I | L | Q | K | E | H | I | D | E | X | S | E | K | L | R | K | A | L | K | S | F |
Template Known Secondary structure |   |
T |  |  |  |  |  |  |
| T | T | S |
|  |  |  |  |  |  |  |  |  |  | T | T |  |  |
|  |  |  | T | T | T |  |  |  |  |
|
|
| T | T |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
|
Template Predicted Secondary structure |   |
|  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
334 | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . |
  |