Job Description P77488 Confidence 100.00% Date Thu Jan 5 12:29:48 GMT 2012 Rank 11 Aligned Residues 575 % Identity 21% Template c1tkcA_ PDB info PDB header:transferase Chain: A: PDB Molecule:transketolase; PDBTitle: specificity of coenzyme binding in thiamin diphosphate2 dependent enzymes: crystal structures of yeast3 transketolase in complex with analogs of thiamin4 diphosphate Resolution 2.70 Å

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		27	.	.	30	.	.		.	.	.	.	.	.	.	40	.	.	.	.	.		.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.									.	70	.	.	.	.	.	.	.	.	.	80	.	.				.	.	.	.	.	.	.	90	.
Predicted Secondary structure								.														.																								.	.	.	.	.	.	.	.															.	.	.										.	.
Query SS confidence								.														.																								.	.	.	.	.	.	.	.															.	.	.										.	.
Query Sequence		S	L	P	K	L	C	.	D	E	L	R	R	Y	L	L	D	S	V	S	R	.	S	S	G	H	F	A	S	G	L	G	T	V	E	L	T	V	A	L	H	Y	V	Y	N	.	.	.	.	.	.	.	.	T	P	F	D	Q	L	I	W	D	V	G	H	Q	A	.	.	.	Y	P	H	K	I	L	T	G	R	.	.
Query Conservation								.														.																								.	.	.	.	.	.	.	.															.	.	.										.	.
Alig confidence								.														.																								.	.	.	.	.	.	.	.															.	.	.										.	.
Template Conservation
Template Sequence		D	I	D	K	L	A	V	S	T	I	R	I	L	A	V	D	T	V	S	K	A	N	S	G	H	P	G	A	P	L	G	M	A	P	A	A	H	V	L	W	S	Q	M	R	M	N	P	T	N	P	D	W	I	N	R	D	R	F	V	L	S	N	G	H	A	V	A	L	L	Y	S	M	L	H	L	T	G	Y	D	L
Template Known Secondary structure																							T		S																		T					T	T		T	T		T	T							S	S	G	G	G											T	T	S	S
Template Predicted Secondary structure
Template SS confidence
		6	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.
			92	.	.	.	.	.	.	.	100	.	.	.		.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.											.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.
Predicted Secondary structure		.													.																																								.	.	.	.	.	.	.	.	.	.
Query SS confidence		.													.																																								.	.	.	.	.	.	.	.	.	.
Query Sequence		.	R	D	K	I	G	T	I	R	Q	K	G	G	.	L	H	P	F	P	W	R	G	E	S	E	Y	D	V	L	S	V	G	H	S	S	T	S	I	S	A	G	I	G	I	A	V	A	A	E	K	E	G	K	.	.	.	.	.	.	.	.	.	.	N	R	R	T	V	C	V	I	G	D	G	A	I	T	A	G	M
Query Conservation		.													.																																								.	.	.	.	.	.	.	.	.	.
Alig confidence		.													.									.																															.	.	.	.	.	.	.	.	.	.
Template Conservation																								.
Template Sequence		S	I	E	D	L	K	Q	F	R	Q	L	G	S	R	T	P	G	H	P	E	F	E	.	L	P	G	V	E	V	T	T	G	P	L	G	Q	G	I	S	N	A	V	G	M	A	M	A	Q	A	N	L	A	A	T	Y	N	K	P	G	F	T	L	S	D	N	Y	T	Y	V	F	L	G	D	G	C	L	Q	E	G	I
Template Known Secondary structure								T	T	T	S	T	T		S			S	S			T	T	.	S	T	T			S				S	T	T																						B	T	T	B																		S
Template Predicted Secondary structure																								.
Template SS confidence
		86	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.		.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.
		160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.		.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.		.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.			.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.
Predicted Secondary structure																			.																			.																		.	.
Query SS confidence																			.																			.																		.	.
Query Sequence		A	F	E	A	M	N	H	A	G	D	I	R	P	D	M	L	V	.	I	L	N	D	N	E	M	S	I	S	E	N	V	G	A	L	N	N	.	H	L	A	Q	L	L	S	G	K	L	Y	S	S	L	R	E	G	.	.	G	K	K	V	F	S	G	V	P	P	I	K	E	L	L	K	R	T	E	E	H	I	K	G
Query Conservation																			.																			.																		.	.
Alig confidence																			.																			.																		.	.															.	.	.
Template Conservation																																																																								.	.	.
Template Sequence		S	S	E	A	S	S	L	A	G	H	L	K	L	G	N	L	I	A	I	Y	D	D	N	K	I	T	I	D	G	A	T	S	I	S	F	D	E	D	V	A	K	R	Y	E	A	Y	G	W	E	V	L	Y	V	E	N	G	N	E	D	L	A	G	I	A	K	A	I	A	Q	A	.	.	.	K	L	S	K	D	K	P
Template Known Secondary structure												T	T		T	T									S	B		S	S	S	B							S										T							T	T	T	T	T													.	.	.	T	T		T	T	S
Template Predicted Secondary structure																																																																								.	.	.
Template SS confidence
		165	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.				.	.	.	.	.	240	.
		236	.	.	.	240	.	.	.	.	.	.	.	.	.								250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.													.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.
Predicted Secondary structure																.	.	.	.	.	.	.																		.	.	.	.	.	.	.	.	.	.	.	.
Query SS confidence																.	.	.	.	.	.	.																		.	.	.	.	.	.	.	.	.	.	.	.
Query Sequence		M	V	V	P	G	T	L	F	E	E	L	G	F	N	.	.	.	.	.	.	.	Y	I	G	P	V	D	G	H	D	V	L	G	L	I	T	T	L	.	.	.	.	.	.	.	.	.	.	.	.	K	N	M	R	D	L	K	G	P	Q	F	L	H	I	M	T	K	K	G	R	G	Y	E	P	A	E	K	D	P	I
Query Conservation																.	.	.	.	.	.	.																		.	.	.	.	.	.	.	.	.	.	.	.
Alig confidence																.	.	.	.	.	.	.																		.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation
Template Sequence		T	L	I	K	M	T	T	T	I	G	Y	G	S	L	H	A	G	S	H	S	V	H	G	A	P	L	K	A	D	D	V	K	Q	L	K	S	K	F	G	F	N	P	D	K	S	F	V	V	P	Q	E	V	Y	D	H	Y	Q	K	T	I	L	K	P	G	V	E	A	N	N	K	W	N	K	L	F	S	E	Y	Q	K
Template Known Secondary structure										T	T	T	T	S	T	T	T	T	S	G	G	G	G	S	S															T	S		T	T			S														T
Template Predicted Secondary structure
Template SS confidence
		242	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.
		297	.	.	300	.													.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.												.	.
Predicted Secondary structure							.	.	.	.	.	.	.	.	.	.	.	.																																																			.	.	.	.	.	.	.	.	.	.	.
Query SS confidence							.	.	.	.	.	.	.	.	.	.	.	.																																																			.	.	.	.	.	.	.	.	.	.	.
Query Sequence		T	F	H	A	V	.	.	.	.	.	.	.	.	.	.	.	.	P	K	F	D	P	S	S	G	C	L	P	K	S	S	G	G	L	P	S	Y	S	K	I	F	G	D	W	L	C	E	T	A	A	K	D	N	K	L	M	A	I	T	P	A	M	R	E	G	S	G	.	.	.	.	.	.	.	.	.	.	.	M	V
Query Conservation							.	.	.	.	.	.	.	.	.	.	.	.																																																			.	.	.	.	.	.	.	.	.	.	.
Alig confidence							.	.	.	.	.	.	.	.	.	.	.	.																																																			.	.	.	.	.	.	.	.	.	.	.
Template Conservation
Template Sequence		K	F	P	E	L	G	A	E	L	A	R	R	L	S	G	Q	L	P	A	N	W	E	S	K	L	P	T	Y	T	A	K	D	S	A	V	A	T	R	K	L	S	E	T	V	L	E	D	V	Y	N	Q	L	P	E	L	I	G	G	S	A	D	L	T	P	S	N	L	T	R	W	K	E	A	L	D	F	Q	P	P	S
Template Known Secondary structure			S													T				T	T	G	G	G	G	S					T	T	S																		T	T		T	T						S	S						T				T	T			B	B			G	G
Template Predicted Secondary structure
Template SS confidence
		322	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.
		354	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.			.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.		.	.	.	.	.	.	430
Predicted Secondary structure																																	.	.																																								.
Query SS confidence																																	.	.																																								.
Query Sequence		E	F	S	R	K	F	P	D	R	Y	F	D	V	A	I	A	E	Q	H	A	V	T	F	A	A	G	L	A	I	G	G	.	.	Y	K	P	I	V	A	I	Y	S	T	F	L	Q	R	A	Y	D	Q	V	L	H	D	V	A	I	Q	K	L	P	V	L	F	A	I	D	R	A	G	I	.	V	G	A	D	G	Q	T
Query Conservation																																	.	.																																								.
Alig confidence																																	.	.																			.																					.
Template Conservation																																																					.
Template Sequence		S	G	S	G	N	Y	S	G	R	Y	I	R	Y	G	I	R	E	H	A	M	G	A	I	M	N	G	I	S	A	F	G	A	N	Y	K	P	Y	G	G	T	F	L	N	F	V	S	Y	A	A	G	A	.	V	R	L	S	A	L	S	G	H	P	V	I	W	V	A	T	H	D	S	I	G	V	G	E	D	G	P	T
Template Known Secondary structure		G	S	S		B	T	T								S																	T	T																			.								T											S	G	G	G		T	T		T	T
Template Predicted Secondary structure																																																					.
Template SS confidence
		402	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.		.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480
		431	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500		.	.	.	.	.	.	.	.	.
Predicted Secondary structure																																																																								.
Query SS confidence																																																																								.
Query Sequence		H	Q	G	A	F	D	L	S	Y	L	R	C	I	P	E	M	V	I	M	T	P	S	D	E	N	E	C	R	Q	M	L	Y	T	G	Y	H	Y	N	D	G	P	S	A	V	R	Y	P	R	G	N	A	V	G	V	E	L	T	P	L	E	K	L	P	I	G	K	G	I	V	K	.	R	R	G	E	K	L	A	I	L
Query Conservation																																																																								.
Alig confidence																																																																								.
Template Conservation
Template Sequence		H	Q	P	I	E	T	L	A	H	F	R	S	L	P	N	I	Q	V	W	R	P	A	D	G	N	E	V	S	A	A	Y	K	N	S	L	E	S	K	H	T	P	S	I	I	A	L	S	R	Q	N	L	P	Q	L	E	G	S	S	I	E	S	A	S	K	G	G	Y	V	L	Q	D	V	A	N	P	D	I	I	L	V
Template Known Secondary structure		S	S		S	S						T	T	S	T	T								S															S	S									S	S						T	T							T	T	S								S	S		S
Template Predicted Secondary structure
Template SS confidence
		481	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540	.	.	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.	.	560
		510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.						.	.	.	.	530	.	.	.	.	.	.	.	.	.	540	.	.	.				.	.	.	.	.	.	550	.	.	.	.	.	.	.	.	.	560	.	.	.	.	.	.	.	.	.	570	.	.	.	.	.	.	.	.	.	580	.
Predicted Secondary structure																		.	.	.	.	.																			.	.	.
Query SS confidence																		.	.	.	.	.																			.	.	.
Query Sequence		N	F	G	T	L	M	P	E	A	A	K	V	A	E	S	L	.	.	.	.	.	N	A	T	L	V	D	M	R	F	V	K	P	L	D	E	A	L	I	.	.	.	L	E	M	A	A	S	H	E	A	L	V	T	V	E	E	N	A	I	M	G	G	A	G	S	G	V	N	E	V	L	M	A	H	R	K	P	V	P
Query Conservation																		.	.	.	.	.																			.	.	.
Alig confidence																		.	.	.	.	.																			.	.	.																						.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation																																																																	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		A	T	G	S	E	V	S	L	S	V	E	A	A	K	T	L	A	A	K	N	I	K	A	R	V	V	S	L	P	D	F	F	T	F	D	K	Q	P	L	E	Y	R	L	S	V	L	P	D	N	V	P	I	M	S	V	E	V	L	A	T	T	C	W	.	.	.	.	.	.	.	.	.	.	.	.	.	G	K	Y	A
Template Known Secondary structure				T																T	T									S							T	S									S		S	S	S							S	S		G	G	G	G	.	.	.	.	.	.	.	.	.	.	.	.	.	G	G	T
Template Predicted Secondary structure																																																																	.	.	.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
		561	.	.	.	.	.	.	.	.	570	.	.	.	.	.	.	.	.	.	580	.	.	.	.	.	.	.	.	.	590	.	.	.	.	.	.	.	.	.	600	.	.	.	.	.	.	.	.	.	610	.	.	.	.	.	.	.	.	.	620	.	.	.														.	.	.	.
		582	.	.	.	.	.	.	.	590	.	.	.	.	.	.	.	.	.	600	.	.	.	.	.	.	.	.	.	610	.	.	.	.	.	.	.	.	.	620
Predicted Secondary structure
Query SS confidence
Query Sequence		V	L	N	I	G	L	P	D	F	F	I	P	Q	G	T	Q	E	E	M	R	A	E	L	G	L	D	A	A	G	M	E	A	K	I	K	A	W	L	A
Query Conservation
Alig confidence								.
Template Conservation								.
Template Sequence		H	Q	S	F	G	I	.	D	R	F	G	A	S	G	K	A	P	E	V	F	K	F	F	G	F	T	P	E	G	V	A	E	R	A	Q	K	T	I	A
Template Known Secondary structure		S						.		S					S										T		S
Template Predicted Secondary structure								.
Template SS confidence
		628	.	630	.	.	.		.	.	.	.	.	.	640	.	.	.	.	.	.	.	.	.	650	.	.	.	.	.	.	.	.	.	660	.	.	.	.	.