|   |
19 | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | |
|
|
|
. | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | |
|
|
|
|
. | 80 | . | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|  | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
W | P | E | R | L | V | L | A | K | S | C | G | F | D | F | V | E | M | S | V | D | E | T | D | E | R | L | S | R | L | D | W | S | A | . |
. |
. |
. |
A | Q | R | T | S | L | V | A | A | M | I | E | T | G | V | G | I | P | S | M | C | L | S | A | H | R | . |
. |
. |
. |
. |
R | F | P | F | G | S | R | D | E | A | V |
Query Conservation |   |
  |   |   |   |   |   |   |
|   |   |   |
|
|   |   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|   |   |   |   |   |   |   |   |   | . | . | . | . | . |   |   |   |   |   |   |   |
|   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |
|
|
|   |
|   |
|
|
|   |   |   |   |   |
|
|
|   |
|   |   |
|   |
|   |
|   |   |
|   |   |   |
|
|   |   |   |   |   |   |
|   |   |   |   |   |   |
|
|
|
|
|
|
|   |
|   |
|
|
|   |   |
|
|
|   |   |
|
|
|
|
|
|
|   |   |
|
Template Sequence |   |
V | E | A | A | F | E | F | F | D | K | I | N | A | P | Y | F | C | F | H | D | R | D | I | A | P | E | G | D | T | L | R | E | T | N | K | N | L | D | T | I | V | A | M | I | K | D | Y | L | K | T | S | K | T | K | V | L | W | G | T | A | N | L | F | S | N | P | R | F | V | H | G | A | S | T | S | C | N | A | D | V |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  | T |
| S |  |  |  |  |  |  |  |  |  | S |
|
|
| S | S |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
| S |
|  |  |  |  |  |  |
|
|
| S | S | S | G | G | G | T | T |
| S | T | T |
| S |
|  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |
|
|
|
|
|
|
|
|
|  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
82 | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . |
  |
  |   |
90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | |
|
|
|
. | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | |
|
|
|
|
|
|
. | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  | . | . | . | . | . | . | . |  |  |
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
Query Sequence |   |
R | E | R | A | R | E | I | M | S | K | A | I | R | L | A | R | D | L | G | I | R | T | I | Q | L | A | G | Y | D | V | Y | Y | E | D | H | . |
. |
. |
. |
D | E | G | T | R | Q | R | F | A | E | G | L | A | W | A | V | E | Q | A | A | A | S | Q | V | M | L | A | V | . |
. |
. |
. |
. |
. |
. |
E | I | M | D | T | A |
Query Conservation |   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |
|
|   |   |   |
|   |   |   |   |
|   |   |   |   |   |   |   | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|   |   |   |
|
|   |
|   |
| . | . | . | . | . | . | . |
|   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
|
|
|
|
|
|
Template Conservation |   |
|
|   |
|   |   |
|
|
|
|
|
|
|
|
|   |
|
|
|
|
|
|   |
|   |
|
|
|
|
|
|
|
|   |   |
|
|
|
|   |   |   |
|   |
|   |
|
|   |
|   |   |   |
|   |
|
|   |   |
|
|
|   |   |   |   |
|
|
|
|
|
|
|   |
|
|   |
|
|
|
Template Sequence |   |
F | A | Y | S | A | A | Q | V | K | K | A | L | E | I | T | K | E | L | G | G | E | N | Y | V | F | W | G | G | R | E | G | Y | E | T | L | L | N | T | D | M | E | F | E | L | D | N | F | A | R | F | L | H | M | A | V | D | Y | A | K | E | I | G | F | E | G | Q | F | L | I | E | P | K | P | K | E | P | T | K | H | Q |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
| S |  |  |  |  |
|
| T | T | S |  |  | S |
| G | G | G |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
| S |  |  |  |  |
|
|
| S |
| S | S | S | S |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
162 | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . |
  |
  |   |
159 | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | |
. | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | |
|
. | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
| . | . |
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
F | M | N | S | I | S | K | W | K | K | W | D | E | M | L | A | S | P | W | . |
F | T | V | Y | P | D | V | G | N | L | S | A | W | G | N | D | V | P | A | E | L | K | L | G | . |
. |
I | D | R | I | A | A | I | H | L | K | D | T | Q | P | V | T | G | Q | S | P | G | Q | F | R | D | V | P | F | G | E | G | C | V | D |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |   |   |   | . |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . |   |   |   |
|   |   |
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|   |
|
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|
|
|
|
|
|
|   |
|
|
|
|   |   |   |
|
|   |   |   |
|
|
|
|
|
|   |
|
|
|
|
|
|
|
|
|
|   |
|
|
|
|   |
|   |   |   |
|   |
|
|
|
|
|   |
|   |
|
|   |
|   |
|
|
|
|
|
| . | . | . |
|
|   |   |   |   |   |   |
|
Template Sequence |   |
Y | D | F | D | V | A | N | V | L | A | F | L | R | K | Y | D | L | D | K | Y | F | K | V | N | I | E | A | N | H | A | T | L | A | F | H | D | F | Q | H | E | L | R | Y | A | R | I | N | G | V | L | G | S | I | D | A | N | T | G | D | M | L | L | G | W | D | T | D | Q | . |
. |
. |
F | P | T | D | I | R | M | T | T |
Template Known Secondary structure |   |
S | S |
| S |  |  |  |  |  |  |  |  |  |  | T | T |
| T | T | T |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
|  |  |  |  |  |  |  |  |  |  | T | T |
|  |  |  |  |  |
|
| B |
|
| T | T | S |
| S |
|
|
| B | . | . | . |
|
|
|
|  |  |  |  |  |
Template Predicted Secondary structure |   |
 |
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  | . | . | . |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
242 | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | |
|
|
310 | . | . | . | . | . | . | . | . |
  |
  |   |
236 | . | . | . | 240 | . | . | . | . | . | . | . | . | . | |
250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | |
|
|
|
|
. | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |
|
|
|
| . |
|
|  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
F | V | G | I | F | K | T | L | H | K | L | N | Y | R | . |
G | S | F | L | I | E | M | W | T | E | K | A | K | E | P | V | L | E | . |
. |
. |
. |
. |
I | I | Q | A | R | R | W | I | E | A | R | M | Q | E | A | G | F | I |
Query Conservation |   |
  |   |   |
|   |   |   |
|   |   |   |
|
|   | . |
|   |
|   |
|
|   |   |   |   |   |   |   |
|   |   |   |   | . | . | . | . | . |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |
|   |   |
Alig confidence |   |
|
| . |
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   | . |
|   |   |
|
|   |   |
|
|   |   |   |
|
|   |
|
|
|
|
|
|
|
|   |
|   |
|   |
|
|
|
|   |   |
|
|   |   |
|
|   |   |
|   |
|
|   |   |
|   |   |   |   |
Template Sequence |   |
L | A | . |
M | Y | E | V | I | K | M | G | G | F | D | K | G | G | L | N | F | D | A | K | V | R | R | A | S | F | E | P | E | D | L | F | L | G | H | I | A | G | M | D | A | F | A | K | G | F | K | V | A | Y | K | L | V |
Template Known Secondary structure |   |
 |  | . |  |  |  |  |  |  | T | T | S |
| S | S |
|
|  |  |  |
|
|
|
|
| T | T |
|
| S | T |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  | . |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
319 | 320 | |
. | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . |
  |