Job Description P37679 Confidence 81.73% Date Thu Jan 5 11:56:53 GMT 2012 Rank 155 Aligned Residues 230 % Identity 9% Template c2cw6B_ PDB info PDB header:lyase Chain: B: PDB Molecule:hydroxymethylglutaryl-coa lyase, mitochondrial; PDBTitle: crystal structure of human hmg-coa lyase: insights into2 catalysis and the molecular basis for3 hydroxymethylglutaric aciduria Resolution 2.10 Å

Show / Hide SS confidence

Show / Hide Conservation and Alignment quality

		21	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60																		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.
Predicted Secondary structure																																										.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query SS confidence																																										.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Sequence		E	R	L	V	L	A	K	S	C	G	F	D	F	V	E	M	S	V	D	E	T	D	E	R	L	S	R	L	D	W	S	A	A	Q	R	T	S	L	V	A	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	A	M	I	E	T	G	V	G	I	P	S	M	C	L	S	A	H	R	R	F	P	F	G
Query Conservation																																										.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Alig confidence																																										.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																		.	.	.	.	.	.
Template Conservation																																																																												.	.	.	.	.	.
Template Sequence		K	L	I	D	M	L	S	E	A	G	L	S	V	I	E	T	T	S	F	V	S	P	K	W	V	P	Q	M	G	D	H	T	E	V	L	K	G	I	Q	K	F	P	G	I	N	Y	P	V	L	T	P	N	L	K	G	F	E	A	A	V	A	A	G	A	K	E	V	V	I	F	G	A	A	S	.	.	.	.	.	.
Template Known Secondary structure										T	T		S										T	T	T		G	G	G	T	T								S				T	T		B							S										T	T		S								S		.	.	.	.	.	.
Template Predicted Secondary structure																																																																												.	.	.	.	.	.
Template SS confidence
		58	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.
		84	.	.	.	.	.	90	.	.	.								.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.
Predicted Secondary structure												.	.	.	.	.	.	.
Query SS confidence												.	.	.	.	.	.	.
Query Sequence		S	R	D	E	A	V	R	E	R	A	.	.	.	.	.	.	.	R	E	I	M	S	K	A	I	R	L	A	R	D	L	G	I	R	T	I	Q	L	A	G	Y	D	V	Y	Y	E	D	H	D	E	G	T	R	Q	R	F	A	E	G	L	A	W	A	V	E	Q	A	A	A	S	Q	V	M	L	A	V	E	I	M	D
Query Conservation												.	.	.	.	.	.	.
Alig confidence		.	.									.	.	.	.	.	.	.																																																					.	.	.	.	.
Template Conservation		.	.																																																																				.	.	.	.	.
Template Sequence		.	.	E	L	F	T	K	K	N	I	N	C	S	I	E	E	S	F	Q	R	F	D	A	I	L	K	A	A	Q	S	A	N	I	S	V	R	G	Y	V	S	C	A	L	G	C	P	Y	E	G	K	I	S	P	A	K	V	A	E	V	T	K	K	F	Y	S	M	G	C	Y	.	.	.	.	.	E	I	S	L	G	D
Template Known Secondary structure		.	.								T	S	S		T	T	T															T	T									S	T	T		B	T	T	T	B	S																T	T		S	.	.	.	.	.
Template Predicted Secondary structure		.	.																																																																				.	.	.	.	.
Template SS confidence
				132	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.						.	200	.	.	.	.
		157	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		T	A	F	M	N	S	I	S	K	W	K	K	W	D	E	M	L	A	S	P	W	F	T	V	Y	P	D	V	G	N	L	S	A	W	G	N	D	V	P	A	E	L	K	L	G	I	D	R	I	A	A	I	H	L	K	D	T	Q	P	V	T	G	Q	S	P	G	Q	F	R	D	V	P	F	G	E	G	C	V	D	F
Query Conservation
Alig confidence																																																																					.	.	.	.	.	.
Template Conservation																																																																					.	.	.	.	.	.
Template Sequence		T	I	G	V	G	T	P	G	I	M	K	D	M	L	S	A	V	M	Q	E	V	P	L	A	A	L	A	V	H	C	H	D	T	Y	G	Q	A	L	A	N	T	L	M	A	L	Q	M	G	V	S	V	V	D	S	S	V	A	G	L	G	G	C	P	Y	A	Q	G	.	.	.	.	.	.	A	S	G	N	L	A	T
Template Known Secondary structure		T	T																			S		G	G	G						B		T	T	S												T	T							B	T	T	S					T	T	S	S	S	.	.	.	.	.	.				B		B
Template Predicted Secondary structure																																																																					.	.	.	.	.	.
Template SS confidence
		205	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.							.	.	.	.	.	.	.
		237	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280
Predicted Secondary structure
Query SS confidence
Query Sequence		V	G	I	F	K	T	L	H	K	L	N	Y	R	G	S	F	L	I	E	M	W	T	E	K	A	K	E	P	V	L	E	I	I	Q	A	R	R	W	I	E	A	R	M	Q
Query Conservation
Alig confidence																		.	.	.	.	.	.	.	.	.	.	.
Template Conservation																		.	.	.	.	.	.	.	.	.	.	.
Template Sequence		E	D	L	V	Y	M	L	E	G	L	G	I	H	T	G	V	.	.	.	.	.	.	.	.	.	.	.	N	L	Q	K	L	L	E	A	G	N	F	I	C	Q	A	L	N
Template Known Secondary structure											T	T		B				.	.	.	.	.	.	.	.	.	.	.																	T
Template Predicted Secondary structure																		.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
		279	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.												.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.

No model constructed - rank, confidence too low

---

Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions