|   |
8 | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |
|
|
|
|  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | V | L | P | E | L | L | T | A | L | D | C | A | P | Q | V | L | L | S | A | P | T | G | A | G | K | S | T | W | L | P | L | Q | L | L | A | H | P | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
G | I | N | G | K | I | I | L | L | E | P | R | R | L | A | A | R | N | V | A | Q |
Query Conservation |   |
  |   |   |   |   |
|   |   |
|
|   |   |   |   |   |
|
|
|   |
|
|
|
|
|
|
|
|
|   |
|
|
|   |
|
|   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |
|
|
|
|
|
|   |
|
|
|   |
|
|   |
|   |
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |
|   |   |
|
|   |   |
|
|   |
|   |   |
|
|
|   |
|
|
|
|
|
|
|
|
|   |   |   |
|
|
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
P | V | Q | K | H | A | I | P | I | I | K | E | K | R | D | L | M | A | C | A | Q | T | G | S | G | K | T | A | A | F | L | L | P | I | L | S | Q | I | Y | S | D | G | P | G | E | A | L | R | A | M | K | E | N | G | R | Y | G | R | R | K | Q | Y | P | I | S | L | V | L | A | P | T | R | E | L | A | V | Q | I | Y | E |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  | T | T |
|
|  |  |  |  |
|
| T | T | S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |
| B | T | T | B | S |
| S | B |
|
| S |  |  |  |  |
| S | S |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
205 | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . |
  |
  |   |
67 | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | |
|
|
|
|
. | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | |
. | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 |
Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|
|  |  |  |  | . | . | . | . | . |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|  |  |  |  |  |  |  |  |
|
|
| . |
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |
|
|
|
|  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
R | L | A | E | L | L | N | E | K | P | G | D | T | V | . |
. |
. |
. |
. |
G | Y | R | M | R | A | Q | N | C | V | G | P | N | T | R | L | E | V | V | T | E | G | V | L | T | R | M | I | Q | R | D | P | . |
E | L | S | G | V | G | L | V | I | L | D | E | F | H | E | R | S | L | Q | A | D | L | A | L | A | L | L | L |
Query Conservation |   |
|
|
|   |   |
|
|   |   |
|
|   |   |
| . | . | . | . | . |
|
|   |
|
|   |
|   |   |   |
|   |   |
|   |
|   |
|   |
|   |
|   |
|
|   |   |
|   |   |
|   | . |   |
|   |   |   |   |   |
|
|
|
|
|   |
|
|
|   |   |   |   |
|
|   |
|
|
|
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
E | A | R | K | F | S | Y | R | S | R | V | R | P | C | V | V | Y | G | G | A | D | I | G | Q | Q | I | R | D | L | E | R | G | C | H | L | L | V | A | T | P | G | R | L | V | D | M | M | E | R | G | K | I | G | L | D | F | C | K | Y | L | V | L | D | E | A | D | . |
. |
R | M | L | D | M | G | F | E | P | Q | I | R |
Template Known Secondary structure |   |
 |  |  |  |  |  | T | T | S | S |
|
|  |  |  |  |
| S | S | S |
|  |  |  |  |  |  |  |  | T | T |
|
| S |  |  |  |  |
|  |  |  |  |  |  |  |  |  | T | T | S | B |
|
| T | T |
|
|  |  |  |  | S | S |  |  | . | . |  |  |  |  | T | T |
|  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  | . | . |  |  |  |
|
|
|
|  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
285 | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | |
|
. | . | . | . | . | . | . | . | . | 360 | . | . |
  |
  |   |
141 | . | . | . | . | . | . | |
|
|
|
. | . | 150 | . | . | . | . | . | . | . | . | . | |
|
160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |
|
| . | . | . | . |
|
|
|  |  |  |  |  |  |
|
|
| . | . |
|  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
D | V | Q | Q | G | L | R | . |
. |
. |
. |
D | D | L | K | L | L | I | M | S | A | T | L | . |
. |
D | N | D | R | L | Q | Q | M | L | P | E | A | P | V | V | I | S | E | G | R | S | F | P | V | E | R | R | Y | L | P | L | P | A | H | Q | R | F | D | D | A | V | A | V | A | T | A | E | M | L | R | Q | E | S | G | S |
Query Conservation |   |
  |   |   |   |   |   |
| . | . | . | . |   |
|
|
|
|
|
|
|
|
|
|
| . | . |
|   |   |   |
|
|   |   |
|   |   |   |   |
|
|   |
|   |
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |
|   |
Alig confidence |   |
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . |   |   |   |   |   |
Template Sequence |   |
R | I | V | E | Q | D | T | M | P | P | K | G | V | R | H | T | M | M | F | S | A | T | F | P | K | E | I | Q | M | L | A | R | D | F | L | D | E | Y | I | F | L | A | V | G | T | S | E | N | I | T | Q | K | V | V | W | V | E | E | S | D | K | R | S | F | L | L | D | L | L | N | A | T | . |
. |
. |
G | K | D | S | L |
Template Known Secondary structure |   |
 |  |  | T | S | S | S |
|
|
| B | T | T | B |  |  |  |  |  |  | S |
|
|
|  |  |  |  |  |  |  |  |  |  |
| S | S |
|  |  |  |  |  |
|
|
| S | S |  |  |  |  |  |  |  |
|
| G | G | G |  |  |  |  |  |  |  |  |  |  | T |
| . | . | . |
| T | T |
|  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
| . | . | . |
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
363 | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | |
|
|
. | . | . | . | . |
  |
  |   |
215 | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
L | L | L | F | L | P | G | V | G | E | I | Q | R | V | Q | E | Q | L | A | S | R | I | G | S | D | V | L | L | C | P | L | Y | G | A | L | S | L | N | D | Q | R | K | A | I | L | P | A | P | Q | G | M | R | K | V | V | L | A | T | N | I | A | E | T | S | L | T | I | E | G | I | R | L | V | V | D | C | A | Q | E | R |
Query Conservation |   |
|
|
|
|
|
|
|   |   |
|
|   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |
|   |   |
|
|
|   |
|
|   |   |
|
|   |   |   |
|   |   |   |   |   |
|   |   |
|
|
|
|
|
|
|
|
|
|   |
|
|
|
|
|   |
|   |   |
|
|
|   |
|
|   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|   |
|   |   |
|   |   |
|
|
|
|
|   |
|   |   |
|
|   |   |   |   | . | . |
Template Sequence |   |
T | L | V | F | V | E | T | K | K | G | A | D | S | L | E | D | F | L | Y | H | E | . |
. |
. |
G | Y | A | C | T | S | I | H | G | D | R | S | Q | R | D | R | E | E | A | L | H | Q | F | R | S | G | K | S | P | I | L | V | A | T | A | V | A | A | R | G | L | D | I | S | N | V | K | H | V | I | N | F | D | L | . |
. |
Template Known Secondary structure |   |
 |  |  |  |
| S | S |  |  |  |  |  |  |  |  |  |  |  |  |  | T | . | . | . | T |
|
|  |  |  |  |
| T | T | S |
|  |  |  |  |  |  |  |  |  |  |  |  |  | T | S | S |
|  |  |  |  |
|  |  |  |  | T | T | S |
|
|
|
|  |  |  |  |  |  | S | S |
| . | . |
Template Predicted Secondary structure |   |
 |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
| . | . | . |
|
|  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
| . | . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
444 | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | |
|
|
. | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480 | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . | . | . | . | . | 510 | . | . | . | . | . | . | . | . | |
|
  |
  |   |
295 | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |
|
|
|  |  |  |  |  |  |
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
V | A | R | F | D | P | R | T | G | L | T | R | L | I | T | Q | R | V | S | Q | A | S | M | T | Q | R | A | G | R | A | G | R | L | E | P | G | I | S | L | H | L | I | A | K | E | Q | A | E | R | A |
Query Conservation |   |
  |   |   |   |
|   |   |   |
|   |   |   |
|   |   |   |   |
|
|   |
|
|
|   |
|
|   |
|
|
|
|
|   |   |   |
|   |   |
|
|
|   |
|   |   |   |   |   |   |
|
Alig confidence |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|   |
|   |   |   |   |
|
|
|   |
|
|   |
|
| . |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
P | S | D | I | E | E | Y | V | H | R | I | G | R | T | G | R | . |
N | L | G | L | A | T | S | F | F | N | E | R | N | I | N | I | T |
Template Known Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
| S | S |  |  |  |  |  |  |  |  | T | T | B |
|
| . |
|
|  |  |  |  |  |  |  |
| G | G | G | G | G | G |  |
Template Predicted Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
| . |
|
|
|  |  |  |  |  |  |
|  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
519 | 520 | . | . | . | . | . | . | . | . | . | 530 | . | . | . | . | |
. | . | . | . | . | 540 | . | . | . | . | . | . | . | . | . | 550 | . |
  |