Job Description P76440 Confidence 100.00% Date Thu Jan 5 12:23:00 GMT 2012 Rank 1 Aligned Residues 405 % Identity 33% Template c1gthD_ PDB info PDB header:oxidoreductase Chain: D: PDB Molecule:dihydropyrimidine dehydrogenase; PDBTitle: dihydropyrimidine dehydrogenase (dpd) from pig, ternary2 complex with nadph and 5-iodouracil Resolution 2.25 Å

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		4	.	.	.	.	.	10	.	.	.		.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.
Predicted Secondary structure												.
Query SS confidence												.
Query Sequence		Q	N	Y	L	D	E	L	T	P	A	.	F	T	S	L	L	A	I	K	E	A	S	R	C	L	L	C	H	D	A	P	C	S	Q	A	C	P	A	Q	T	D	P	G	K	F	I	R	S	I	Y	F	R	N	F	K	G	A	A	E	T	I	R	E	N	N	A	L	G	A	V	C	A	R	V	C	P	T	E	K	L
Query Conservation												.
Alig confidence												.
Template Conservation
Template Sequence		E	N	N	F	D	D	I	K	H	T	T	L	G	E	R	G	A	L	R	E	A	M	R	C	L	K	C	A	D	A	P	C	Q	K	S	C	P	T	H	L	D	I	K	S	F	I	T	S	I	S	N	K	N	Y	Y	G	A	A	K	M	I	F	S	D	N	P	L	G	L	T	C	G	M	V	C	P	T	S	D	L
Template Known Secondary structure		T	T							T	T																		T	T						T	S	T	T													T	T														T	T										G	G	G	S
Template Predicted Secondary structure
Template SS confidence
		56	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.
		83	.	.	.	.	.	.	90	.	.	.	.		.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.										.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.		150	.
Predicted Secondary structure														.																								.	.	.	.	.	.	.	.	.																																	.
Query SS confidence														.																								.	.	.	.	.	.	.	.	.																																	.
Query Sequence		C	Q	S	G	C	T	R	A	G	V	D	A	.	P	I	D	I	G	R	L	Q	R	F	V	T	D	F	E	Q	Q	T	G	M	E	I	Y	.	.	.	.	.	.	.	.	.	Q	P	G	T	K	T	L	G	K	V	A	I	I	G	A	G	P	A	G	L	Q	A	S	V	T	L	T	N	Q	G	Y	D	.	V	T
Query Conservation														.																								.	.	.	.	.	.	.	.	.																																	.
Alig confidence														.																								.	.	.	.	.	.	.	.	.																																	.
Template Conservation
Template Sequence		C	V	G	G	C	N	L	Y	A	T	E	E	G	S	I	N	I	G	G	L	Q	Q	F	A	S	E	V	F	K	A	M	N	I	P	Q	I	R	N	P	C	L	P	S	Q	E	K	M	P	E	A	Y	S	A	K	I	A	L	L	G	A	G	P	A	S	I	S	C	A	S	F	L	A	R	L	G	Y	S	D	I	T
Template Known Secondary structure		G	G	G	G		G	G	G	G	S	T	T																				T				B			T	T	S			G	G	G	S		G	G	G	G									S														T
Template Predicted Secondary structure
Template SS confidence
		136	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.
		152	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.		200	.	.	.	.	.	.	.	.	.		210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.
Predicted Secondary structure																																																		.											.
Query SS confidence																																																		.											.
Query Sequence		I	Y	E	K	E	A	H	P	G	G	W	L	R	N	G	I	P	Q	F	R	L	P	Q	S	V	L	D	A	E	I	A	R	I	E	K	M	G	V	T	I	K	C	N	N	E	V	G	N	.	T	L	T	L	E	Q	L	K	A	E	.	N	R	A	V	L	V	T	V	G	L	S	S	G	S	G	L	P	L	F	E
Query Conservation																																																		.											.
Alig confidence																																																		.											.
Template Conservation
Template Sequence		I	F	E	K	Q	E	Y	V	G	G	L	S	T	S	E	I	P	Q	F	R	L	P	Y	D	V	V	N	F	E	I	E	L	M	K	D	L	G	V	K	I	I	C	G	K	S	L	S	E	N	E	I	T	L	N	T	L	K	E	E	G	Y	K	A	A	F	I	G	I	G	L	P	E	P	K	T	D	D	I	F	Q
Template Known Secondary structure					S	S	S	S		S	T					T	S		T	T	T	S														T	T	T						S			B	S	T	T	S	B								T	T																	G	G	G	T
Template Predicted Secondary structure
Template SS confidence
		216	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.
						230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250										.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.
Predicted Secondary structure		.	.	.	.																						.	.	.	.	.	.	.	.	.
Query SS confidence		.	.	.	.																						.	.	.	.	.	.	.	.	.
Query Sequence		.	.	.	.	H	S	D	V	E	I	A	V	D	F	L	Q	R	A	R	Q	A	Q	G	D	I	.	.	.	.	.	.	.	.	.	S	I	P	Q	S	A	L	I	I	G	G	G	D	V	A	M	D	V	A	S	T	L	K	V	L	G	C	Q	A	V	T	C	V	A	R	E	E	L	D	E	F	P	A	S	E	K
Query Conservation		.	.	.	.																						.	.	.	.	.	.	.	.	.
Alig confidence		.	.	.	.																						.	.	.	.	.	.	.	.	.
Template Conservation
Template Sequence		G	L	T	Q	D	Q	G	F	Y	T	S	K	D	F	L	P	L	V	A	K	S	S	K	A	G	M	C	A	C	H	S	P	L	P	S	I	R	G	A	V	I	V	L	G	A	G	D	T	A	F	D	C	A	T	S	A	L	R	C	G	A	R	R	V	F	L	V	F	R	K	G	F	V	N	I	R	A	V	P	E
Template Known Secondary structure		T			T	T	T	T																	T	T	T		S	S									S								S													T	T		S							S	S		G	G	G			S
Template Predicted Secondary structure
Template SS confidence
		296	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.
		297	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.																330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.							.
Predicted Secondary structure																																			.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																										.	.	.	.	.	.
Query SS confidence																																			.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																										.	.	.	.	.	.
Query Sequence		E	F	T	S	A	R	E	L	G	V	S	I	I	D	G	F	T	P	V	A	V	E	G	N	K	V	T	F	K	H	V	R	L	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	S	G	E	L	T	M	A	A	D	K	I	I	L	A	V	G	Q	H	A	R	L	D	A	F	A	.	.	.	.	.	.	E
Query Conservation																																			.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																										.	.	.	.	.	.
Alig confidence																																			.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																										.	.	.	.	.	.
Template Conservation
Template Sequence		E	V	E	L	A	K	E	E	K	C	E	F	L	P	F	L	S	P	R	K	V	I	V	K	G	G	R	I	V	A	V	Q	F	V	R	T	E	Q	D	E	T	G	K	W	N	E	D	E	D	Q	I	V	H	L	K	A	D	V	V	I	S	A	F	G	S	V	L	R	D	P	K	V	K	E	A	L	S	P	I	K
Template Known Secondary structure									T	T						S										S	S	S													S	S	S															S																		T	T	T	T	S
Template Predicted Secondary structure
Template SS confidence
		376	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.
		356	.	.	.	360	.	.	.	.	.		.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.
Predicted Secondary structure												.
Query SS confidence												.
Query Sequence		L	E	P	Q	R	N	T	I	K	T	.	Q	N	Y	Q	T	R	D	P	Q	V	F	A	A	G	D	I	V	E	G	D	K	T	V	V	Y	A	V	K	T	G	K	E	A	A	E	A	I	H	H	Y	L	E	G
Query Conservation												.
Alig confidence												.
Template Conservation
Template Sequence		F	N	R	W	D	L	P	E	V	D	P	E	T	M	Q	T	S	E	P	W	V	F	A	G	G	D	I	V	G	M	A	N	T	T	V	E	S	V	N	D	G	K	Q	A	S	W	Y	I	H	K	Y	I	Q	A
Template Known Secondary structure		B		T	T	S	S	B				T	T	T		B		S	S	T	T					G	G	G	G	T				S
Template Predicted Secondary structure
Template SS confidence
		456	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.