|   |
2 | . | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | |
. | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 |
Predicted Secondary structure |   |
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
| . |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
T | I | K | N | V | I | C | D | I | D | G | V | L | M | H | D | N | V | A | V | P | G | A | A | E | F | L | H | G | I | M | D | K | G | L | P | L | V | L | L | T | N | Y | P | S | Q | T | G | Q | D | L | A | N | R | F | A | T | A | G | V | . |
D | V | P | D | S | V | F | Y | T | S | A | M | A | T | A | D | F | L | R |
Query Conservation |   |
  |
|
|   |
|
|
|
|   |
|
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|
|   |
|   |
|
|
|
|
|
|
|   |   |   |   |   |   |
|   |   |
|   |   |
|
|   |   |
|   |   |   |
|   |   |   |   |   |   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
K | Y | K | C | I | F | F | D | A | F | G | V | L | K | T | Y | N | G | L | L | P | G | I | E | N | T | F | D | Y | L | K | A | Q | G | Q | D | Y | Y | I | V | T | N | D | A | S | R | S | P | E | Q | L | A | D | S | Y | H | K | L | G | L | F | S | I | T | A | D | K | I | I | S | S | G | X | I | T | K | E | Y | I | D |
Template Known Secondary structure |   |
G |
| S |  |  |  |  |
|
| B | T | T | T |  |  | T | T |  |  |
| T | T |  |  |  |  |  |  |  |  |  |  |  | T |
|  |  |  |  |  |  |
|
|
| S | S |
|  |  |  |  |  |  |  |  |  |  | T | T |
| T | T |
|
| G | G | G |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |
|  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
12 | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . |
  |
  |   |
81 | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | |
Predicted Secondary structure |   |
 |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
| . |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
Query Sequence |   |
R | Q | E | G | K | K | A | Y | V | V | G | E | G | A | L | I | H | E | L | Y | K | A | G | F | T | I | T | D | V | N | P | D | F | V | I | V | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
G | E | T | R | S | Y | N | W | D | M | M | H | K | A | A | Y | F | V | A | N | G | A | R | F | I | A | T | N | P | D | . |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
L | K | V | D | G | G | I | V | A | Y | L | G | T | A | N | S | A | N | Y | L | V | S | D | G | I | K | X | L | P | V | S | A | I | D | D | S | N | I | G | E | V | N | A | L | V | L | L | D | D | E | G | F | N | W | F | H | D | L | N | K | T | V | N | L | L | R | K | R | T | I | P | A | I | V | A | N | T | D | N | T |
Template Known Secondary structure |   |
 |  |
|
| S |  |  |  |  |  |  | S |
|  |  |  |  |  | T | T |
| B | T | T |  |  |  |  |  | G | G | G |
|
| T | T | T | G | G | G |  |  |  |  |  |  |
|
| S | S | S | S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
| S |  |
Template Predicted Secondary structure |   |
 |
|
|
|
|
|  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
92 | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . |
  |
  |   |
|
|
147 | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | |
|
|
|
. | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 |
Predicted Secondary structure |   |
. | . |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  | . | . | . | . |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
Query SS confidence |   |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
. |
. |
T | H | G | R | G | F | Y | P | A | C | G | A | L | C | A | G | I | E | K | I | S | G | R | K | P | F | Y | V | G | K | P | S | P | W | . |
. |
. |
. |
I | I | R | A | A | L | N | K | M | Q | A | H | S | E | E | T | V | I | V | G | D | N | L | R | T | D | I | L | A | G | F | Q | A | G | L | E | T | I | L | V |
Query Conservation |   |
. | . |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|   |   |   |   |
|
|   |   |
|   |   |
|
|   |   |   |
|   |
|
Alig confidence |   |
. | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |
|
|   |   |
|
|   |
|   |
|
|
|   |   |   |
|
|
|   |   |
|   |   |
|
|   |   |   |
|   |
|
Template Sequence |   |
Y | P | L | T | K | T | D | V | A | I | A | I | G | G | V | A | T | X | I | E | S | I | L | G | R | R | F | I | R | F | G | K | P | D | S | Q | X | F | X | F | A | Y | D | X | L | R | Q | K | X | E | I | S | K | R | E | I | L | X | V | G | D | T | L | H | T | D | I | L | G | G | N | K | F | G | L | D | T | A | L | V |
Template Known Secondary structure |   |
 |  | S | S | S | S |
|  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |
| S |
|  |  |  |  | S | T | T | S | S |  |  |  |  |  |  |  |  |  |  |  |  |  | S |
|
|
| G | G | G |  |  |  |  |  | S |
| T | T | T |  |  |  |  |  |  |  | T | T |
|  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
172 | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . |
  |
  |   |
221 | . | . | . | . | . | . | . | . | 230 | . | . | |
|
|
|
. | . | . | . | . | . | . | 240 | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|  |  |  |  |  |  | . | . | . | . |
|
|
|
|
|
|  |  |  |
|
|  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
L | S | G | V | S | S | L | D | D | I | D | S | . |
. |
. |
. |
M | P | F | R | P | S | W | I | Y | P | S | V |
Query Conservation |   |
  |   |
|   |   |   |   |   |   |   |   |   | . | . | . | . |   |   |   |   |
|
|   |
|
|   |
|
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|   |   |
|   |
Template Sequence |   |
L | T | G | N | T | R | I | D | D | A | E | T | K | I | K | S | T | G | I | V | P | T | H | I | C | E | S | A |
Template Known Secondary structure |   |
S | S | S | S | S |
| T | T | T |  |  |  |  |  |  |  |  |
|
|
|
| S |  |  |  | S |
| S |
Template Predicted Secondary structure |   |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |
|
|  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
252 | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . |
  |