Job Description P00893 Confidence 100.00% Date Thu Jan 5 10:57:03 GMT 2012 Rank 20 Aligned Residues 519 % Identity 19% Template c2w93A_ PDB info PDB header:lyase Chain: A: PDB Molecule:pyruvate decarboxylase isozyme 1; PDBTitle: crystal structure of the saccharomyces cerevisiae pyruvate2 decarboxylase variant e477q in complex with the surrogate3 pyruvamide Resolution 1.60 Å

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		2	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.
Predicted Secondary structure
Query SS confidence
Query Sequence		E	M	L	S	G	A	E	M	V	V	R	S	L	I	D	Q	G	V	K	Q	V	F	G	Y	P	G	G	A	V	L	D	I	Y	D	A	L	H	T	V	G	G	I	D	H	V	L	V	R	H	E	Q	A	A	V	H	M	A	D	G	L	A	R	A	T	G	E	V	G	V	V	L	V	T	S	G	P	G	A	T	N
Query Conservation
Alig confidence																																																																					.
Template Conservation																																																																					.
Template Sequence		S	E	I	T	L	G	K	Y	L	F	E	R	L	K	Q	V	N	V	N	T	V	F	G	L	P	G	D	F	N	L	S	L	L	D	K	I	Y	E	V	E	G	M	R	W	A	G	N	A	N	E	L	N	A	A	Y	A	A	D	G	Y	A	R	I	K	G	M	S	.	C	I	I	T	T	F	G	V	G	E	L	S
Template Known Secondary structure																	T	T										G	G	G						G	G	G	G	S	T	T							S																	S			.						T	T
Template Predicted Secondary structure																																																																					.
Template SS confidence
		2	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.		.	70	.	.	.	.	.	.	.	.	.	80
		82	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.									.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.
Predicted Secondary structure																																				.	.	.	.	.	.	.	.
Query SS confidence																																				.	.	.	.	.	.	.	.
Query Sequence		A	I	T	G	I	A	T	A	Y	M	D	S	I	P	L	V	V	L	S	G	Q	V	A	T	S	L	I	G	Y	D	A	F	Q	E	.	.	.	.	.	.	.	.	C	D	M	V	G	I	S	R	P	V	V	K	H	S	F	L	V	K	Q	T	E	D	I	P	Q	V	L	K	K	A	F	W	L	A	A	S	G	R
Query Conservation																																				.	.	.	.	.	.	.	.
Alig confidence																																				.	.	.	.	.	.	.	.
Template Conservation
Template Sequence		A	L	N	G	I	A	G	S	Y	A	E	H	V	G	V	L	H	V	V	G	V	P	S	I	S	S	Q	A	K	Q	L	L	L	H	H	T	L	G	N	G	D	F	T	V	F	H	R	M	S	A	N	I	S	E	T	T	A	M	I	T	D	I	A	T	A	P	A	E	I	D	R	C	I	R	T	T	Y	V	T	Q
Template Known Secondary structure												T	T																	T	T				T	T	S		S	S	S		S	S								T	T		S								T	T	T																T
Template Predicted Secondary structure
Template SS confidence
		81	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160
		154	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		P	G	P	V	V	V	D	L	P	K	D	I	L	N	P	A	N	K	L	P	Y	V	W	P	E	S	V	S	M	R	S	Y	N	P	T	T	T	G	H	K	G	Q	I	K	R	A	L	Q	T	L	V	A	A	K	K	P	V	V	Y	V	G	G	G	A	I	T	A	G	C	H	Q	Q	L	K	E	T	V	E	A	L
Query Conservation
Alig confidence		.																								.
Template Conservation		.																								.
Template Sequence		.	R	P	V	Y	L	G	L	P	A	N	L	V	D	L	N	V	P	A	K	L	L	Q	T	.	P	I	D	M	S	L	K	P	N	D	A	E	S	E	K	E	V	I	D	T	I	L	A	L	V	K	D	A	K	N	P	V	I	L	A	D	A	C	C	S	R	H	D	V	K	A	E	T	K	K	L	I	D	L	T
Template Known Secondary structure		.	S								T	T	G	G	G	S				G	G	G	G	G	S	.					S																								S	S												T	T
Template Predicted Secondary structure		.																								.
Template SS confidence
			161	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.		.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.
		234	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.		.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.
Predicted Secondary structure																											.
Query SS confidence																											.
Query Sequence		N	L	P	V	V	C	S	L	M	G	L	G	A	F	P	A	T	H	R	Q	A	L	G	M	L	.	G	M	H	G	T	Y	E	A	N	M	T	M	H	N	A	D	V	I	F	A	V	G	V	R	F	D	D	R	T	T	N	N	L	A	K	Y	C	P	N	A	T	V	L	H	I	D	I	D	P	T	S	I	S	K
Query Conservation																											.
Alig confidence																											.																											.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation																																																						.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		Q	F	P	A	F	V	T	P	M	G	K	G	S	I	D	E	Q	H	P	R	Y	G	G	V	Y	V	G	T	L	S	K	P	E	V	K	E	A	V	E	S	A	D	L	I	L	S	V	G	A	L	T	K	.	.	.	.	.	.	.	.	.	.	.	.	.	.	N	I	V	E	F	H	S	D	H	M	K	I	R	N
Template Known Secondary structure									T	T	T	T	T	S	S		T	T	S	T	T							G	G	G	S										T		S						S					.	.	.	.	.	.	.	.	.	.	.	.	.	.							S	S					T	T
Template Predicted Secondary structure																																																						.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
		239	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290															.	.	.	.	.	.	.	.	.	300	.	.	.	.
		313	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		T	V	T	A	D	I	P	I	V	G	D	A	R	Q	V	L	E	Q	M	L	E	L	L	S	Q	E	S	A	H	Q	P	L	D	E	I	R	D	W	W	Q	Q	I	E	Q	W	R	A	R	Q	C	L	K	Y	D	T	H	S	E	K	I	K	P	Q	A	V	I	E	T	L	W	R	L	T	K	G	D	A	Y	V	T
Query Conservation
Alig confidence																																		.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation																																		.	.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		A	T	F	P	G	V	Q	M	K	F	V	L	Q	K	L	L	T	N	I	A	D	A	A	K	G	Y	K	P	V	A	V	P	.	.	.	.	.	.	.	.	.	.	.	.	.	A	R	T	P	A	N	A	A	V	P	A	S	T	P	L	K	Q	E	W	M	W	N	Q	L	G	N	F	L	Q	E	G	D	V	V	I
Template Known Secondary structure						T																		T	T	T								.	.	.	.	.	.	.	.	.	.	.	.	.											T	T		B										G	G	G	T			T	T
Template Predicted Secondary structure																																		.	.	.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
		319	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350														.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.
		393	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.					.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.
Predicted Secondary structure																																													.	.	.	.
Query SS confidence																																													.	.	.	.
Query Sequence		S	D	V	G	Q	H	Q	M	F	A	A	L	Y	Y	P	F	D	K	P	R	R	W	I	N	S	G	G	L	G	T	M	G	F	G	L	P	A	A	L	G	V	K	M	.	.	.	.	A	L	P	E	E	T	V	V	C	V	T	G	D	G	S	I	Q	M	N	I	Q	E	L	S	T	A	L	Q	Y	E	L	P	V
Query Conservation																																													.	.	.	.
Alig confidence																.																													.	.	.	.
Template Conservation																.
Template Sequence		A	E	T	G	T	S	A	F	G	I	N	Q	T	T	.	F	P	N	N	T	Y	G	I	S	Q	V	L	W	G	S	I	G	F	T	T	G	A	T	L	G	A	A	F	A	A	E	E	I	D	P	K	K	R	V	I	L	F	I	G	D	G	S	L	Q	L	T	V	Q	E	I	S	T	M	I	R	W	G	L	K	P
Template Known Secondary structure				T	T						G	G	G	S		.			S	S							T	T	T			T	T																		T	T																T	T								T	T
Template Predicted Secondary structure																.
Template SS confidence
		386	.	.	.	390	.	.	.	.	.	.	.	.	.		400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.
		469	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.				.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540	.	.	.	.	.
Predicted Secondary structure																																																		.	.	.
Query SS confidence																																																		.	.	.
Query Sequence		L	V	V	N	L	N	N	R	Y	L	G	M	V	K	Q	W	Q	D	M	I	Y	S	G	R	H	S	Q	S	Y	M	Q	S	L	P	D	F	V	R	L	A	E	A	Y	G	H	V	G	I	.	.	.	Q	I	S	H	P	H	E	L	E	S	K	L	S	E	A	L	E	Q	V	R	N	N	R	L	V	F	V	D	V
Query Conservation																																																		.	.	.
Alig confidence																			.	.	.	.	.																											.	.	.																			.
Template Conservation																			.	.	.	.	.																																																.
Template Sequence		Y	L	F	V	L	N	N	D	G	Y	T	I	Q	K	L	I	H	.	.	.	.	.	G	P	K	A	Q	Y	N	E	I	Q	G	W	D	H	L	S	L	L	P	T	F	G	A	K	D	Y	E	T	H	R	V	A	T	T	G	E	W	D	K	L	T	Q	D	K	S	F	N	.	D	N	S	K	I	R	M	I	E	V
Template Known Secondary structure								S	S	S						T	T	S	.	.	.	.	.		T	T		G	G	G							G	G	G					T	T		S	S								B									T		T	T	T	T	.	S			S
Template Predicted Secondary structure																			.	.	.	.	.																																																.
Template SS confidence
		465	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.						.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.		.	530	.	.	.	.	.	.	.	.
		546	.	.	.	550	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		T	V	D	G	S	E	H	V	Y	P	M	Q
Query Conservation
Alig confidence
Template Conservation
Template Sequence		M	L	P	V	F	D	A	P	Q	N	L	V
Template Known Secondary structure					T	T
Template Predicted Secondary structure
Template SS confidence
		539	540	.	.	.	.	.	.	.	.	.	550