|   |
20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | |
|
|
|
. | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |
|
|
|  |  |  |  |  |  |  | . | . | . | . |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
M | T | V | A | A | S | V | Q | A | K | T | L | V | Y | C | S | E | G | S | P | E | G | F | N | P | Q | L | F | T | S | G | T | T | Y | D | A | S | S | . |
. |
. |
. |
V | P | L | Y | N | R | L | V | E | F | K | I | G | T | T | E | V | I | P | G | L | A | E | K | W | E | V | S | E | D | G | K | T | Y | T | F | H | L |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |
|
|   |
|   |   |   |   |   |
|   |   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . |   |   |
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|   |   |   |   |   |
|   |
|
|   |   |   |
|
|   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |
|
|
|
|   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
| . |   |   |   |   |   |   |
|   |
|
|   |   |
|   |   |
|   |
|   |   |
|   |
|
|   |
|
Template Sequence |   |
Q | N | P | D | K | A | I | K | G | G | N | L | K | V | A | Y | Q | S | D | S | P | X | K | A | Q | W | L | S | G | L | S | N | D | A | T | F | A | T | X | S | G | P | G | G | G | Q | D | G | L | F | F | T | D | . |
S | G | F | K | F | I | K | G | G | A | A | D | V | A | L | D | K | E | S | K | T | A | T | I | T | L |
Template Known Secondary structure |   |
|
| S | S |
|
|
| S | S |
|  |  |  |  |  |  |  |
| S | S |
|
|
|
|
|
| S | T | T | T |
|
|
|  |  |  |  |  |  | T | G | G | G | T | T | T | T | B |
|
|  |  |
| . | T | T | S | B |  |  | S |
| S | S |  |  |  |  |  |  | T | T | T | T |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |
| . |
|
|
|
|  |  |  |
|  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
24 | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | |
. | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . |
  |
  |   |
96 | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | |
|
|
|
. | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | |
|
|
. | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
| . | . | . |
|  |  |  |  |  |  |
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
Query Sequence |   |
R | K | G | V | K | W | H | D | N | K | E | F | K | P | T | R | E | L | N | A | D | D | V | V | F | S | F | D | R | Q | K | N | A | Q | N | P | Y | H | K | V | S | G | G | S | Y | E | Y | F | E | . |
. |
. |
. |
G | M | G | L | P | E | L | I | S | E | V | K | K | V | D | D | . |
. |
. |
N | T | V | Q | F | V | L | T |
Query Conservation |   |
|   |   |   |   |
|
|
|
|   |   |   |   |   |   |   |
|
|
|
|   |
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . |   |   |   |   |   |   |   |
|   |   |
|   |   |   |
|   | . | . | . |   |
|
|   |
|   |
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |
|
|   |
|
|
|
|   | . | . | . | . | . | . |
|
|
|
|   |
|
|   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |
|
|   |   |   |   |   |
|
|   |
|   |
|   |
Template Sequence |   |
R | K | D | L | K | W | S | D | G | S | . |
. |
. |
. |
. |
. |
E | V | T | A | K | D | Y | E | F | T | Y | E | T | I | A | N | P | A | Y | G | S | D | R | W | T | D | S | L | A | N | I | V | G | L | S | D | Y | H | T | G | K | A | K | T | I | S | G | I | T | F | P | D | G | E | N | G | K | V | I | K | V | Q | F | K |
Template Known Secondary structure |   |
| T | T |
| B |
| T | T | S |
| . | . | . | . | . | . | B |
|
|  |  |  |  |  |  |  |  |  |  |  |  |
| G | G | G |
|
| S |
|
|
| G | G | G | G | G | B | T | T |  |  |  |  |  | T | T | S |
| S | S |
| T | T |  |  |
| T | T |
| T | T | S | S |  |  |  |  |  | B | S |
Template Predicted Secondary structure |   |
|
|
|
|  |  |
|
|
|
| . | . | . | . | . | . |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
103 | . | . | . | . | . | . | 110 | . | . | |
|
|
|
|
|
. | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . |
  |
  |   |
169 | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | |
. | . | . | . | . | . | 190 | . | . | . | . | . | . | . | |
|
. | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |  |  |
|
|
| . |
|
|
|
|  |  |  |  |  |  |
|
|
|
| . | . |
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
R | P | E | A | P | F | L | A | D | L | A | M | D | F | A | . |
S | I | L | S | K | E | Y | A | D | A | M | M | K | A | . |
. |
G | T | P | E | K | L | D | L | N | P | I | G | T | G | P | F | Q | L | Q | Q | Y | Q | K | D | S | R | I | R | Y | K | A | F | D | G | Y | W | G | T | K | P | Q | I | D | T | L | V | F | S |
Query Conservation |   |
  |
|   |   |   |   |   |   |   |
|
|   |   |   |   | . |   |
|   |   |   |   |   |   |   |   |   |   |   |   | . | . |   |   |   |   |   |   |   |   |   |   |
|
|
|
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |
|   |   |   |   |   |   |
|   |   |
|   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|
|
|   |
|   |   |   |   |   |   |   |   |
|   |
|   |
|
|   |   |
|   |   |   |   |
|   |   |
|   |
|   |   |   |
Template Sequence |   |
E | X | K | P | G | X | T | Q | S | G | N | G | Y | F | L | E | T | V | A | P | Y | Q | Y | L | K | D | V | A | P | K | D | L | A | S | S | P | K | T | T | T | K | P | L | V | T | G | P | F | K | P | E | N | V | V | A | G | E | S | I | K | Y | V | P | N | P | Y | Y | W | G | E | K | P | K | L | N | S | I | T | Y | E |
Template Known Secondary structure |   |
S |
|
| G | G | G | G | B | T | T |
| S | S | S |
|
| B |
|
|
|  |  |  |  | T | T | S |
| G | G | G | T | T | T | S | G | G | G | T | T | S |
|
|
|
| S | S |  |  |  |  |  |  |  | T | T | T |  |  |  |  |  |  |
| T | T |
| S | S |
|
|
| S |
| S |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |
|
|
|
|
|  |  |  |
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
177 | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . |
  |
  |   |
246 | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
300 | . | . | . | . | . | . | . | . | . | 310 | . | . |
Predicted Secondary structure |   |
 |  |
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |
| . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
I | T | P | D | A | S | V | R | Y | A | K | L | Q | K | N | E | C | Q | V | M | P | Y | P | N | P | A | D | I | A | R | M | K | Q | D | K | S | I | N | L | M | E | M | P | G | L | N | V | G | Y | L | S | Y | N | V | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Q | K | K | P | L | D | D | V | K | V | R | Q | A |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|   | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |
|   |   |
|
|   |
|
Alig confidence |   |
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   | . |   |   |   |   |   |
|
|   |   |
|   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |
|   |   |
|
|
|
|
Template Sequence |   |
V | V | S | T | . |
A | K | S | V | A | A | L | S | S | S | K | Y | D | I | I | N | G | X | V | S | S | Q | Y | K | Q | V | K | N | L | K | G | Y | K | V | L | G | Q | Q | A | X | Y | I | S | L | X | Y | Y | N | L | G | H | Y | D | A | K | N | S | I | N | V | Q | D | R | K | T | P | L | Q | D | Q | N | V | R | Q | A |
Template Known Secondary structure |   |
 |  |
|  | . |  |  |  |  |  |  |  |  | T | T |
|
| S |  |  |  |
|
|
| G | G | G |  |  |  |  |  | T |
| T | T |  |  |  |  |  |  |  |
| S |  |  |  |  |  |  |  |
|
|
|  |  |  | T | T | T | T |  |  |  |
|
|
|
|
| G | G | G | S |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |
|  | . |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
257 | . | . | 260 | |
. | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . |
  |
  |   |
313 | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | |
|
. | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | |
|
|
|
|
|
|
|
. | . | . | . | . | 380 | . | . |
Predicted Secondary structure |   |
 |  |  |
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . |
|  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
Query Sequence |   |
L | T | Y | A | V | N | K | D | A | I | I | K | A | V | Y | Q | G | A | G | V | S | A | K | N | L | I | P | P | T | M | W | G | Y | N | D | D | V | Q | D | . |
. |
Y | T | Y | D | P | E | K | A | K | A | L | L | K | E | A | G | L | E | K | G | F | S | I | . |
. |
. |
. |
. |
. |
. |
. |
D | L | W | A | M | P | V | Q |
Query Conservation |   |
|   |   |
|
|
|
|   |   |
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . |   |   |   |
|   |   |   |
|   |   |
|
|   |   |
|
|   |   |   |
|   |   |   | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |   |
|
|
|
|   |   |
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |
|
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |
|   |   |   |   |
Template Sequence |   |
I | G | Y | A | R | N | V | A | E | V | D | N | K | F | S | N | G | L | S | T | P | A | N | S | L | I | P | P | I | F | K | Q | F | T | S | S | S | V | K | G | Y | E | K | Q | D | L | D | K | A | N | K | L | L | D | E | D | G | W | K | L | N | K | S | T | G | Y | R | E | K | D | G | K | E | L | S | L | V | Y | A | A |
Template Known Secondary structure |   |
 |  |  |  |
|
|  |  |  |  |  |  |  |  | T | T | T | S |  |  |  |
| S | S | S | S |
| T | T | S | T | T | S |
|
| T | T |
|
|
| S | S | S |
|
|  |  |  |  |  |  |  |  |  | T | T | T |
|  |  |
| S | S | S | S | S |  |  |  | T | T |  |  |
|  |  |  |  |  |
|
Template Predicted Secondary structure |   |
 |  |  |  |
|
|  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
336 | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . |
  |
  |   |
383 | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | |
|
|
|
|
|
|
. | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  | . | . | . | . | . | . | . |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
R | P | Y | N | P | N | A | R | R | M | A | E | M | I | Q | A | D | W | A | K | V | G | V | Q | A | K | I | V | T | Y | E | W | G | E | Y | L | K | R | A | . |
. |
. |
. |
. |
. |
. |
K | D | G | E | H | Q | T | V | M | M | G | W | T | G | D | N | G | D | P | D | N | F | F | A | T | L | F | S | C | A | A | S | E | Q |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |
|   |   |   |
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |
|   |   |   |
|
|   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . |   |   |   |   |   |
Template Sequence |   |
R | V | G | D | A | N | A | E | T | I | A | Q | N | Y | I | Q | Q | W | K | K | I | G | V | K | V | S | L | Y | N | G | K | L | X | E | F | N | S | W | V | D | H | X | T | T | P | P | G | A | N | D | W | D | I | T | D | G | S | W | S | L | A | S | E | P | S | Q | Q | D | L | . |
. |
. |
. |
. |
. |
F | S | A | A | A |
Template Known Secondary structure |   |
B | S |
| S | T | T |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|  |  |  |  | G | G | G | S |
| B |
|  |  |  |  |  |  |  |  |  | S | T | T |
|
| S | S |
| S |  |  |  |  |  |  |  |
|
| S | S |
|
|
|  |  |  | . | . | . | . | . | . |  | S | T | T |
|
Template Predicted Secondary structure |   |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  | . | . | . | . | . | . |  |
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
416 | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480 | . | . | . | . | |
|
|
|
|
|
. | . | . | . | . |
  |
  |   |
456 | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | |
|
. | . | . | 480 | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . | . | . | . | . | 510 | . | . | . | . | . | . | . | . | . | 520 | . | . | . | . | . | . | . | . | . | 530 | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  | . | . |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|  |  |  |  |  |  |
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |
|  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
G | S | N | Y | S | K | W | C | Y | K | P | F | E | D | L | I | Q | P | A | R | A | . |
. |
T | D | D | H | N | K | R | V | E | L | Y | K | Q | A | Q | V | V | M | H | D | Q | A | P | A | L | I | I | A | H | S | T | V | F | E | P | V | R | K | E | V | K | G | Y | V | V | D | P | L | G | K | H | H | F | E | N | V | S |
Query Conservation |   |
  |   |
|   |   |   |   |   |   |   |   |   |
|   |
|
|   |   |   |   |   | . | . |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |
|   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |   |
|   |   |   |   |   |   |   |   |
|   |
Template Sequence |   |
P | Y | N | F | G | H | F | N | D | S | E | I | T | K | D | L | N | D | I | D | S | A | K | S | E | N | P | T | Y | R | K | A | A | F | V | K | Y | Q | E | D | X | N | K | K | A | Y | V | I | P | T | N | F | X | L | N | Y | T | P | V | N | K | R | V | V | G | X | T | L | D | Y | G | A | X | N | T | W | S | E | I | G |
Template Known Secondary structure |   |
T | T |
| T | T |
|
|
|
|  |  |  |  |  |  |  |  |  |  | T | S | G | G | G | G | S |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| S |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |  |  | S |
| B |
|
| T | T |
| S |
|  |  |  |  |
|  |
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |
|
|
|
|
|
|
|  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . | . | . | . | . | 510 | . | . | . | . | . | . | . | . | . | 520 | . | . | . | . | . | . | . | . | . | 530 | . | . | . | . | . | . | . | . | . | 540 | . | . | . | . | . | . | . | . | . | 550 | . | . | . | . | . | . | . | . | . | 560 | . | . | . | . | . | . | . | . | . |
  |
  |   |
534 | . |
Predicted Secondary structure |   |
 |
|
Query SS confidence |   |
|
|
Query Sequence |   |
I | E |
Query Conservation |   |
  |   |
Alig confidence |   |
|
|
Template Conservation |   |
|   |
Template Sequence |   |
V | S |
Template Known Secondary structure |   |
 | S |
Template Predicted Secondary structure |   |
 |  |
Template SS confidence |   |
|
|
  |   |
570 | . |
  |