Secondary structure and disorder prediction

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Sequence		M	A	T	L	L	Q	L	H	F	A	F	N	G	P	F	G	D	A	M	A	E	Q	L	K	P	L	A	E	S	I	N	Q	E	P	G	F	L	W	K	V	W	T	E	S	E	K	N	H	E	A	G	G	I	Y	L	F	T	D	E	K
Secondary structure
SS confidence
Disorder		?	?	?																																								?		?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.
Sequence		S	A	L	A	Y	L	E	K	H	T	A	R	L	K	N	L	G	V	E	E	V	V	A	K	V	F	D	V	N	E	P	L	S	Q	I	N	Q	A	K	L	A
Secondary structure
SS confidence
Disorder															?	?	?		?													?	?			?	?	?	?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 2hiq chain A domain 1 Region: 2 - 97 Aligned: 96 Modelled: 96 Confidence: 100.0% Identity: 100% Fold: Ferredoxin-like Superfamily: Dimeric alpha+beta barrel Family: Hypothetical protein YdhR Phyre2 PDB 1wd6 chain B Region: 2 - 97 Aligned: 96 Modelled: 96 Confidence: 100.0% Identity: 99% PDB header:structural genomics, unknown function Chain: B: PDB Molecule:protein ydhr; PDBTitle: crystal structure of jw1657 from escherichia coli Phyre2 PDB 3hx9 chain B Region: 2 - 91 Aligned: 90 Modelled: 90 Confidence: 97.0% Identity: 12% PDB header:oxidoreductase Chain: B: PDB Molecule:protein rv3592; PDBTitle: structure of heme-degrader, mhud (rv3592), from2 mycobacterium tuberculosis with two hemes bound in its3 active site Phyre2 PDB 1y0h chain A Region: 1 - 93 Aligned: 93 Modelled: 93 Confidence: 96.4% Identity: 16% Fold: Ferredoxin-like Superfamily: Dimeric alpha+beta barrel Family: PA3566-like Phyre2 PDB 3fgv chain B Region: 1 - 88 Aligned: 88 Modelled: 87 Confidence: 95.1% Identity: 15% PDB header:oxidoreductase Chain: B: PDB Molecule:uncharacterized protein with ferredoxin-like fold; PDBTitle: crystal structure of a putative antibiotic biosynthesis monooxygenase2 (spo2313) from silicibacter pomeroyi dss-3 at 1.30 a resolution Phyre2 PDB 2omo chain C Region: 2 - 91 Aligned: 90 Modelled: 89 Confidence: 95.1% Identity: 16% PDB header:oxidoreductase Chain: C: PDB Molecule:duf176; PDBTitle: putative antibiotic biosynthesis monooxygenase from nitrosomonas2 europaea Phyre2 PDB 2gff chain B Region: 17 - 93 Aligned: 77 Modelled: 77 Confidence: 95.1% Identity: 19% PDB header:sugar binding protein Chain: B: PDB Molecule:lsrg protein; PDBTitle: crystal structure of yersinia pestis lsrg Phyre2 PDB 3bm7 chain A Region: 17 - 90 Aligned: 74 Modelled: 74 Confidence: 94.4% Identity: 18% PDB header:oxidoreductase Chain: A: PDB Molecule:protein of unknown function with ferredoxin-like fold; PDBTitle: crystal structure of a putative antibiotic biosynthesis monooxygenase2 (cc_2132) from caulobacter crescentus cb15 at 1.35 a resolution Phyre2 PDB 3e8o chain B Region: 4 - 94 Aligned: 91 Modelled: 91 Confidence: 94.3% Identity: 14% PDB header:oxidoreductase Chain: B: PDB Molecule:uncharacterized protein with erredoxin-like fold; PDBTitle: crystal structure of a putative antibiotic biosynthesis monooxygenase2 (dr_2100) from deinococcus radiodurans at 1.40 a resolution Phyre2 PDB 3kng chain A Region: 2 - 90 Aligned: 88 Modelled: 89 Confidence: 93.7% Identity: 15% PDB header:oxidoreductase Chain: A: PDB Molecule:snoab; PDBTitle: crystal structure of snoab, a cofactor-independent oxygenase2 from streptomyces nogalater, determined to 1.9 resolution Phyre2 PDB 2omo chain A domain 1 Region: 2 - 91 Aligned: 90 Modelled: 89 Confidence: 92.7% Identity: 16% Fold: Ferredoxin-like Superfamily: Dimeric alpha+beta barrel Family: PA3566-like Phyre2 PDB 1iuj chain A Region: 3 - 89 Aligned: 87 Modelled: 87 Confidence: 92.5% Identity: 16% Fold: Ferredoxin-like Superfamily: Dimeric alpha+beta barrel Family: PG130-like Phyre2 PDB 3fj2 chain A Region: 3 - 69 Aligned: 67 Modelled: 67 Confidence: 89.9% Identity: 6% PDB header:unknown function Chain: A: PDB Molecule:monooxygenase-like protein; PDBTitle: crystal structure of a monooxygenase-like protein (lin2316) from2 listeria innocua at 1.85 a resolution Phyre2 PDB 2pd1 chain A domain 1 Region: 2 - 91 Aligned: 89 Modelled: 90 Confidence: 87.4% Identity: 17% Fold: Ferredoxin-like Superfamily: Dimeric alpha+beta barrel Family: PA3566-like Phyre2 PDB 3bn7 chain A Region: 7 - 87 Aligned: 81 Modelled: 81 Confidence: 86.3% Identity: 10% PDB header:unknown function Chain: A: PDB Molecule:ferredoxin-like protein; PDBTitle: crystal structure of a dimeric ferredoxin-like protein (cc_2267) from2 caulobacter crescentus cb15 at 1.64 a resolution Phyre2 PDB 1x7v chain A Region: 2 - 90 Aligned: 88 Modelled: 89 Confidence: 85.0% Identity: 14% Fold: Ferredoxin-like Superfamily: Dimeric alpha+beta barrel Family: PA3566-like Phyre2 PDB 2bbe chain A Region: 1 - 87 Aligned: 87 Modelled: 87 Confidence: 84.4% Identity: 15% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:hypothetical protein so0527; PDBTitle: crystal structure of protein so0527 from shewanella oneidensis Phyre2 PDB 2zdp chain A domain 1 Region: 3 - 68 Aligned: 65 Modelled: 66 Confidence: 84.3% Identity: 14% Fold: Ferredoxin-like Superfamily: Dimeric alpha+beta barrel Family: PG130-like Phyre2 PDB 2ril chain A Region: 2 - 90 Aligned: 86 Modelled: 89 Confidence: 72.7% Identity: 15% PDB header:oxidoreductase Chain: A: PDB Molecule:antibiotic biosynthesis monooxygenase; PDBTitle: crystal structure of a putative monooxygenase (yp_001095275.1) from2 shewanella loihica pv-4 at 1.26 a resolution Phyre2 PDB 2fb0 chain A Region: 5 - 86 Aligned: 82 Modelled: 82 Confidence: 71.1% Identity: 16% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:conserved hypothetical protein; PDBTitle: crystal structure of conserved protein of unknown function from2 bacteroides thetaiotaomicron vpi-5482 at 2.10 a resolution, possible3 oxidoreductase Phyre2 1 d2hiqa1 2 c1wd6B_ 3 c3hx9B_ 4 d1y0ha_ 5 c3fgvB_ 6 c2omoC_ 7 c2gffB_ 8 c3bm7A_ 9 c3e8oB_ 10 c3kngA_ 11 d2omoa1 12 d1iuja_ 13 c3fj2A_ 14 d2pd1a1 15 c3bn7A_ 16 d1x7va_ 17 c2bbeA_ 18 d2zdpa1 19 c2rilA_ 20 c2fb0A_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 d2hiqa1 100.0 100 Fold:Ferredoxin-like Superfamily:Dimeric alpha+beta barrel Family:Hypothetical protein YdhR 2 c1wd6B_ 100.0 99 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:protein ydhr; PDBTitle: crystal structure of jw1657 from escherichia coli 3 c3hx9B_ 97.0 12 PDB header:oxidoreductase Chain: B: PDB Molecule:protein rv3592; PDBTitle: structure of heme-degrader, mhud (rv3592), from2 mycobacterium tuberculosis with two hemes bound in its3 active site 4 d1y0ha_ 96.4 16 Fold:Ferredoxin-like Superfamily:Dimeric alpha+beta barrel Family:PA3566-like 5 c3fgvB_ 95.1 15 PDB header:oxidoreductase Chain: B: PDB Molecule:uncharacterized protein with ferredoxin-like fold; PDBTitle: crystal structure of a putative antibiotic biosynthesis monooxygenase2 (spo2313) from silicibacter pomeroyi dss-3 at 1.30 a resolution 6 c2omoC_ 95.1 16 PDB header:oxidoreductase Chain: C: PDB Molecule:duf176; PDBTitle: putative antibiotic biosynthesis monooxygenase from nitrosomonas2 europaea 7 c2gffB_ 95.1 19 PDB header:sugar binding protein Chain: B: PDB Molecule:lsrg protein; PDBTitle: crystal structure of yersinia pestis lsrg 8 c3bm7A_ 94.4 18 PDB header:oxidoreductase Chain: A: PDB Molecule:protein of unknown function with ferredoxin-like fold; PDBTitle: crystal structure of a putative antibiotic biosynthesis monooxygenase2 (cc_2132) from caulobacter crescentus cb15 at 1.35 a resolution 9 c3e8oB_ 94.3 14 PDB header:oxidoreductase Chain: B: PDB Molecule:uncharacterized protein with erredoxin-like fold; PDBTitle: crystal structure of a putative antibiotic biosynthesis monooxygenase2 (dr_2100) from deinococcus radiodurans at 1.40 a resolution 10 c3kngA_ 93.7 15 PDB header:oxidoreductase Chain: A: PDB Molecule:snoab; PDBTitle: crystal structure of snoab, a cofactor-independent oxygenase2 from streptomyces nogalater, determined to 1.9 resolution 11 d2omoa1 92.7 16 Fold:Ferredoxin-like Superfamily:Dimeric alpha+beta barrel Family:PA3566-like 12 d1iuja_ 92.5 16 Fold:Ferredoxin-like Superfamily:Dimeric alpha+beta barrel Family:PG130-like 13 c3fj2A_ 89.9 6 PDB header:unknown function Chain: A: PDB Molecule:monooxygenase-like protein; PDBTitle: crystal structure of a monooxygenase-like protein (lin2316) from2 listeria innocua at 1.85 a resolution 14 d2pd1a1 87.4 17 Fold:Ferredoxin-like Superfamily:Dimeric alpha+beta barrel Family:PA3566-like 15 c3bn7A_ 86.3 10 PDB header:unknown function Chain: A: PDB Molecule:ferredoxin-like protein; PDBTitle: crystal structure of a dimeric ferredoxin-like protein (cc_2267) from2 caulobacter crescentus cb15 at 1.64 a resolution 16 d1x7va_ 85.0 14 Fold:Ferredoxin-like Superfamily:Dimeric alpha+beta barrel Family:PA3566-like 17 c2bbeA_ 84.4 15 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:hypothetical protein so0527; PDBTitle: crystal structure of protein so0527 from shewanella oneidensis 18 d2zdpa1 84.3 14 Fold:Ferredoxin-like Superfamily:Dimeric alpha+beta barrel Family:PG130-like 19 c2rilA_ 72.7 15 PDB header:oxidoreductase Chain: A: PDB Molecule:antibiotic biosynthesis monooxygenase; PDBTitle: crystal structure of a putative monooxygenase (yp_001095275.1) from2 shewanella loihica pv-4 at 1.26 a resolution 20 c2fb0A_ 71.1 16 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:conserved hypothetical protein; PDBTitle: crystal structure of conserved protein of unknown function from2 bacteroides thetaiotaomicron vpi-5482 at 2.10 a resolution, possible3 oxidoreductase 21 d1xbwa_ not modelled 69.0 15 Fold:Ferredoxin-like Superfamily:Dimeric alpha+beta barrel Family:PG130-like 22 d1lq9a_ not modelled 68.2 17 Fold:Ferredoxin-like Superfamily:Dimeric alpha+beta barrel Family:Actinorhodin biosynthesis monooxygenase ActVa-Orf6 23 c2qycA_ not modelled 66.1 17 PDB header:unknown function Chain: A: PDB Molecule:ferredoxin-like protein; PDBTitle: crystal structure of a dimeric ferredoxin-like protein (bb1511) from2 bordetella bronchiseptica rb50 at 1.90 a resolution 24 c3f44A_ not modelled 63.4 13 PDB header:oxidoreductase Chain: A: PDB Molecule:putative monooxygenase; PDBTitle: crystal structure of putative monooxygenase (yp_193413.1) from2 lactobacillus acidophilus ncfm at 1.55 a resolution 25 d1xrsb2 not modelled 63.1 27 Fold:Dodecin subunit-like Superfamily:D-lysine 5,6-aminomutase beta subunit KamE, N-terminal domain Family:D-lysine 5,6-aminomutase beta subunit KamE, N-terminal domain 26 d1q8ba_ not modelled 62.6 19 Fold:Ferredoxin-like Superfamily:Dimeric alpha+beta barrel Family:Hypothetical protein YjcS 27 c3kkfA_ not modelled 59.0 20 PDB header:oxidoreductase Chain: A: PDB Molecule:putative antibiotic biosynthesis monooxygenase; PDBTitle: crystal structure of putative antibiotic biosynthesis2 monooxygenase (np_810307.1) from bacteriodes3 thetaiotaomicron vpi-5482 at 1.30 a resolution 28 c3gz7B_ not modelled 55.5 5 PDB header:biosynthetic protein Chain: B: PDB Molecule:putative antibiotic biosynthesis monooxygenase; PDBTitle: crystal structure of putative antibiotic biosynthesis2 monooxygenase (np_888398.1) from bordetella bronchiseptica3 at 2.15 a resolution 29 c3mcsB_ not modelled 53.1 16 PDB header:oxidoreductase Chain: B: PDB Molecule:putative monooxygenase; PDBTitle: crystal structure of putative monooxygenase (fn1347) from2 fusobacterium nucleatum subsp. nucleatum atcc 25586 at 2.55 a3 resolution 30 d1tuva_ not modelled 43.4 11 Fold:Ferredoxin-like Superfamily:Dimeric alpha+beta barrel Family:PA3566-like 31 c3bdeA_ not modelled 42.4 11 PDB header:unknown function Chain: A: PDB Molecule:mll5499 protein; PDBTitle: crystal structure of a dabb family protein with a ferredoxin-like fold2 (mll5499) from mesorhizobium loti maff303099 at 1.79 a resolution 32 c2jyaA_ not modelled 41.3 21 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein atu1810; PDBTitle: nmr solution structure of protein atu1810 from agrobacterium2 tumefaciens. northeast structural genomics consortium target atr23,3 ontario centre for structural proteomics target atc1776 33 d1tr0a_ not modelled 29.8 14 Fold:Ferredoxin-like Superfamily:Dimeric alpha+beta barrel Family:Plant stress-induced protein 34 d1q4ra_ not modelled 25.7 16 Fold:Ferredoxin-like Superfamily:Dimeric alpha+beta barrel Family:Plant stress-induced protein 35 d1tz0a_ not modelled 24.9 11 Fold:Ferredoxin-like Superfamily:Dimeric alpha+beta barrel Family:PG130-like 36 d1rjja_ not modelled 21.9 17 Fold:Ferredoxin-like Superfamily:Dimeric alpha+beta barrel Family:Plant stress-induced protein 37 c3bb5B_ not modelled 21.9 17 PDB header:unknown function Chain: B: PDB Molecule:stress responsive alpha-beta protein; PDBTitle: crystal structure of a dimeric ferredoxin-like protein of unknown2 function (jann_3925) from jannaschia sp. ccs1 at 2.30 a resolution 38 c3hfkB_ not modelled 20.0 18 PDB header:isomerase Chain: B: PDB Molecule:4-methylmuconolactone methylisomerase; PDBTitle: crystal structure of 4-methylmuconolactone methylisomerase2 (h52a) in complex with 4-methylmuconolactone 39 c1qysA_ not modelled 19.5 12 PDB header:de novo protein Chain: A: PDB Molecule:top7; PDBTitle: crystal structure of top7: a computationally designed2 protein with a novel fold 40 d1tvna1 not modelled 19.3 9 Fold:TIM beta/alpha-barrel Superfamily:(Trans)glycosidases Family:beta-glycanases 41 d2fzia1 not modelled 18.7 14 Fold:Dihydrofolate reductase-like Superfamily:Dihydrofolate reductase-like Family:Dihydrofolate reductases 42 c3bguA_ not modelled 18.0 13 PDB header:unknown function Chain: A: PDB Molecule:ferredoxin-like protein of unknown function; PDBTitle: crystal structure of a dimeric ferredoxin-like protein of unknown2 function (tfu_0763) from thermobifida fusca yx at 1.50 a resolution 43 c3a24A_ not modelled 17.6 19 PDB header:hydrolase Chain: A: PDB Molecule:alpha-galactosidase; PDBTitle: crystal structure of bt1871 retaining glycosidase 44 c2jvfA_ not modelled 16.9 16 PDB header:de novo protein Chain: A: PDB Molecule:de novo protein m7; PDBTitle: solution structure of m7, a computationally-designed2 artificial protein 45 d2ftsa2 not modelled 16.3 33 Fold:MoeA N-terminal region -like Superfamily:MoeA N-terminal region -like Family:MoeA N-terminal region -like 46 d1iyjb2 not modelled 15.8 24 Fold:BRCA2 tower domain Superfamily:BRCA2 tower domain Family:BRCA2 tower domain 47 c3h2zA_ not modelled 14.8 26 PDB header:oxidoreductase Chain: A: PDB Molecule:mannitol-1-phosphate 5-dehydrogenase; PDBTitle: the crystal structure of mannitol-1-phosphate dehydrogenase from2 shigella flexneri 48 d1mlia_ not modelled 11.6 11 Fold:Ferredoxin-like Superfamily:Dimeric alpha+beta barrel Family:Muconalactone isomerase, MLI 49 c3fmbA_ not modelled 11.0 11 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:dimeric protein of unknown function and ferredoxin-like PDBTitle: crystal structure of dimeric protein of unknown function and2 ferredoxin-like fold (yp_212648.1) from bacteroides fragilis nctc3 9343 at 1.85 a resolution 50 c3bsuF_ not modelled 10.2 38 PDB header:hydrolase/rna/dna Chain: F: PDB Molecule:ribonuclease h1; PDBTitle: hybrid-binding domain of human rnase h1 in complex with 12-2 mer rna/dna 51 d1tp6a_ not modelled 10.2 25 Fold:Cystatin-like Superfamily:NTF2-like Family:PA1314-like 52 d1lj8a3 not modelled 9.8 15 Fold:6-phosphogluconate dehydrogenase C-terminal domain-like Superfamily:6-phosphogluconate dehydrogenase C-terminal domain-like Family:Mannitol 2-dehydrogenase 53 c2khdA_ not modelled 8.6 15 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:uncharacterized protein vc_a0919; PDBTitle: solution nmr structure of vc_a0919 from vibrio cholerae.2 northeast structural genomics consortium target vcr52 54 d2nn6g2 not modelled 8.6 20 Fold:Barrel-sandwich hybrid Superfamily:Ribosomal L27 protein-like Family:ECR1 N-terminal domain-like 55 c2hq3A_ not modelled 8.1 13 PDB header:metal transport Chain: A: PDB Molecule:nosl protein; PDBTitle: solution nmr structure of the apo-nosl protein from2 achromobacter cycloclastes 56 c2zq0B_ not modelled 7.9 9 PDB header:hydrolase Chain: B: PDB Molecule:alpha-glucosidase (alpha-glucosidase susb); PDBTitle: crystal structure of susb complexed with acarbose 57 c2wb1J_ not modelled 7.6 14 PDB header:transcription Chain: J: PDB Molecule:dna-directed rna polymerase rpo13 subunit; PDBTitle: the complete structure of the archaeal 13-subunit dna-2 directed rna polymerase 58 d1mjea2 not modelled 7.4 16 Fold:BRCA2 tower domain Superfamily:BRCA2 tower domain Family:BRCA2 tower domain 59 c2waqQ_ not modelled 7.3 14 PDB header:transcription Chain: Q: PDB Molecule:dna-directed rna polymerase rpo13 subunit; PDBTitle: the complete structure of the archaeal 13-subunit dna-2 directed rna polymerase 60 c2z0rA_ not modelled 7.0 33 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:putative uncharacterized protein ttha0547; PDBTitle: crystal structure of hypothetical protein ttha0547 61 c2wb1Q_ not modelled 6.9 15 PDB header:transcription Chain: Q: PDB Molecule:dna-directed rna polymerase rpo13 subunit; PDBTitle: the complete structure of the archaeal 13-subunit dna-2 directed rna polymerase 62 d1qhka_ not modelled 6.6 27 Fold:MbtH/L9 domain-like Superfamily:L9 N-domain-like Family:N-terminal domain of RNase HI 63 d1s6la2 not modelled 6.6 27 Fold:NosL/MerB-like Superfamily:NosL/MerB-like Family:MerB-like 64 c3hkzY_ not modelled 6.5 9 PDB header:transferase Chain: Y: PDB Molecule:dna-directed rna polymerase subunit 13; PDBTitle: the x-ray crystal structure of rna polymerase from archaea 65 d1mwqa_ not modelled 6.3 13 Fold:Ferredoxin-like Superfamily:Dimeric alpha+beta barrel Family:YciI-like 66 c2gjhA_ not modelled 6.1 14 PDB header:de novo protein Chain: A: PDB Molecule:designed protein; PDBTitle: nmr structure of cfr (c-terminal fragment of2 computationally designed novel-topology protein top7) 67 d2hpua1 not modelled 5.9 13 Fold:NosL/MerB-like Superfamily:NosL/MerB-like Family:NosL-like

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0