|   |
2 | . | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . |
Predicted Secondary structure |   |
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | I | K | L | I | A | I | D | M | D | G | T | L | L | L | P | D | H | T | I | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
S | P | A | V | K | N | A | I | A | A | A | R | A | R | G | V | N | V | V | L | T | T | G | R | P | Y | A | G | V | H | N | Y | L | K | E |
Query Conservation |   |
  |
|
|   |
|   |   |
|
|
|
|
|
|   |   |   |   |   |   |
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |
|   |   |
|   |   |   |
|   |   |   |   |   |   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . |
Template Conservation |   |
  |
|   |   |
|   |   |
|
|
|
|
|
|
|   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |
|   |   |   |   |   |   |
|   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . |
Template Sequence |   |
K | V | T | A | V | I | F | D | K | T | G | T | L | T | K | G | K | P | E | V | T | D | L | V | P | L | N | G | D | E | R | E | L | L | R | L | A | A | I | A | E | R | R | S | E | H | P | I | A | E | A | I | V | K | K | A | L | E | H | G | I | E | L | G | E | P | E | K | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Template Known Secondary structure |   |
|
|
|  |  |  |  |  | T |  |  |  |  | B |
| S |
|
|  |  |  |  |  |  |  | S | S | S |
|  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
| S |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
|
|
|
|
| S | S | . | . | . | . | . | . | . | . | . | . | . | . |
Template Predicted Secondary structure |   |
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  | . | . | . | . | . | . | . | . | . | . | . | . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
417 | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480 | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
  |
  |   |
57 | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|
|  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
L | H | M | E | Q | P | G | D | Y | C | I | T | Y | N | G | A | L | V | Q | K | A | A | D | G | S | T | V | A | Q | T | A | L | S | Y | D | D | Y | R | F | L | E | K | L | S | R | E | V | G | S | H | F | H | A | L | D | R | T | T | L | Y | T | A | N | R | D | I | S | Y | Y | T | V | H | E | S | F | V | A | T | I | P |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
. | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
Template Conservation |   |
. | . | . | . |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |
|   |   |   |   |   |   |
|   | . | . | . | . | . | . | . | . | . |   |   |   |   |
|   |   |
|
Template Sequence |   |
. |
. |
. |
. |
V | E | V | I | A | G | E | G | V | V | A | D | G | I | L | V | G | N | K | R | L | X | E | D | F | G | V | A | V | S | N | E | V | E | L | A | L | E | K | L | E | R | E | A | K | T | A | V | I | V | A | R | N | G | R | V | E | G | I | . |
. |
. |
. |
. |
. |
. |
. |
. |
I | A | V | S | D | T | L | K |
Template Known Secondary structure |   |
. | . | . | . |  |  |  |  | T | T | T |  |  |  |  | T | T |  |  |  |  |
|  |  |  |  |  |  | T | T |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|  |  |  |  |  |  |  | T | T |  |  |  |  |  | . | . | . | . | . | . | . | . | . |  |  |  |  |
|
| B |
|
Template Predicted Secondary structure |   |
. | . | . | . |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |
|
|  |  |  |  |  | . | . | . | . | . | . | . | . | . |  |  |  |
|
|  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
|
|
|
485 | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . | . | . | . | . | 510 | . | . | . | . | . | . | . | . | . | 520 | . | . | . | . | . | . | . | . | . | 530 | . | . | . | . | . | . | . | . | . | 540 | . | . | . | |
|
|
|
|
|
|
|
|
. | . | . | . | . | . | 550 | . |
  |
  |   |
137 | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |
|
|  |  |  |
|
|
|
|  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
L | V | F | C | E | A | E | K | M | D | P | N | T | Q | F | L | K | V | M | M | I | D | E | P | A | I | L | D | Q | A | I | A | R | I | P | Q | E | V | K | E | K | Y | T | V | L | K | S | A | P | Y | F | L | E | I | L | D | K | R | V | N | K | G | T | G | V | K | S | L | A | D | V | L | G | I | K | P | E | E | I | M |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |
|   |   |
|   |   |   |
|
|   |
|   |
|
|
|
|
|   |   |   |
|
|   |   |
|
|   |   |
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |
|   |   |   |
|   |   |
|   |   |   |
|   |   |
|
| . |   |
|   |   |
|   |
Template Sequence |   |
E | S | A | K | P | A | V | Q | E | L | K | R | X | G | I | K | V | G | X | I | T | G | D | N | W | R | S | A | E | A | I | S | R | E | L | N | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
L | D | L | V | I | A | E | V | L | P | H | Q | K | S | E | E | V | K | K | L | Q | . |
A | K | E | V | V | A |
Template Known Secondary structure |   |
T | T |  |  |  |  |  |  |  |  |  |  | T | T |
|  |  |  |  |  |
| S | S |
|  |  |  |  |  |  |  |  |  |  | T | T | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
| S |  |  |  |
| S |
|
| T | T |  |  |  |  |  |  |  |  |  | T | . | T | T | S |
|  |  |
Template Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  | . |
|
|
|  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
552 | . | . | . | . | . | . | . | 560 | . | . | . | . | . | . | . | . | . | 570 | . | . | . | . | . | . | . | . | . | 580 | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | 590 | . | . | . | . | . | . | . | . | . | 600 | . | . | . | . | . | . | . | . | |
. | 610 | . | . | . | . |
  |
  |   |
217 | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |
|
|  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | I | G | D | Q | E | N | D | I | A | M | I | E | Y | A | G | V | G | V | A | M | D | N | A | I | P | S | V | K | E | V | A | N | F | V | T | K | S | N | L | E | D | G | V | A | F | A | I | E |
Query Conservation |   |
  |   |
|
|
|   |
|
|   |   |
|
|   |   |
|   |   |   |
|
|
|   |
|
|   |   |   |   |
|   |   |
|
|   |
|   |   |   |   |   |   |   |
|
|   |   |   |
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|
|
|
|
|   |
|
|   |   |
|
|   |   |
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . |   |
|
|
|
|   |   |   |   |   |   |   |
|   |   |   |
|   |
Template Sequence |   |
F | V | G | D | G | I | N | D | A | P | A | L | A | Q | A | D | L | G | I | A | V | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
G | D | I | V | L | I | R | D | D | L | R | D | V | V | A | A | I | Q |
Template Known Secondary structure |   |
 |  |  |
| S | S | T | T |  |  |  |  |  |  | S | S |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . |
|
|  |  |  | S | S |
|
| T |  |  |  |  |  |  |  | T |
Template Predicted Secondary structure |   |
 |  |  |
|
|  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
615 | . | . | . | . | 620 | . | . | . | . | . | . | . | . | . | 630 | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
. | . | . | . | 640 | . | . | . | . | . | . | . | . | . | 650 | . | . | . |
  |