|   |
2 | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . |
Predicted Secondary structure |   |
|
|  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
K | N | S | K | A | I | L | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Q | V | P | G | T | M | K | I | I | S | A | E | I | P | V | P | K | E | D | E | V | L | I | K | V | E | Y | V | G | I | C | G | S | D | V | H | G | F | E | S | G | P | F | I | P | P | K | D | P | N | Q | E | I | G | L | G | H |
Query Conservation |   |
|   |   |   |
|
|   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |
|   |   |
|   |   |   |   |   |
|   |
|   |   |   |   |   |
|
|
|
|
|
|   |
|   |   |
|
|   |   |
|   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |
|   |
Alig confidence |   |
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |
|
|   |
|   |
|   |   |   |
|
|
|
|
|
|   |
|   |
|
|   |   |   |
|   |   |   |   |   |
| . | . | . |   |   |   |   |   |   |   |   |
|   |
|   |
|
|
Template Sequence |   |
S | E | X | K | A | L | L | L | V | G | D | G | Y | T | K | T | P | S | G | S | A | L | E | A | X | E | P | Y | L | E | Q | G | R | I | A | V | P | A | P | G | P | S | Q | V | L | I | K | V | N | L | A | S | I | N | P | S | D | V | A | F | I | K | G | . |
. |
. |
Q | Y | G | Q | P | R | V | K | G | R | P | A | G | F |
Template Known Secondary structure |   |
S |  |  |  |  |  |  |  |
| S |
| B | S |
| S | S |
|
|
| S |
|
|
|
| S | T | T | T |  |  |  |  |  |  |  |
|
|
|
|
| T | T |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  | T | T | . | . | . |
| S | S | S |
| B |
| T | T | S | B |
|
| S |
Template Predicted Secondary structure |   |
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|  |  |  |  |  |  |  |
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
8 | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | |
|
|
. | . | . | . | . | . | . | . | . | 80 | . | . | . | . |
  |
  |   |
66 | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . |
Predicted Secondary structure |   |
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|  |  |  |
|  |  |
|
|
|
|
|
|  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
E | C | A | G | T | V | V | A | V | G | S | R | V | R | K | F | K | P | G | D | R | V | N | I | E | P | G | V | P | C | G | H | C | R | Y | C | L | E | G | K | Y | N | I | C | P | D | V | D | F | M | A | T | Q | P | N | Y | R | G | A | L | T | H | Y | L | C | H | P | E | S | F | T | Y | K | L | P | D | N | M | D | T |
Query Conservation |   |
|   |   |
|   |
|   |   |
|
|   |   |
|   |   |   |   |
|
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |   |
|   |
|
|   |
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
E | G | V | G | T | I | V | A | G | G | D | E | P | Y | A | K | S | L | V | G | K | R | V | A | F | A | T | G | L | S | N | W | G | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
S | W | A | E | Y | A | V | A | E | A | A | A | C | I | P | L | L | D | T | V | R | D |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |
| S | S |  |  |  |  |  |  | T | T |
|  |  |  |  |  |
| T | T | S | S |
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | S | S | B | S |  |  |  |  |  | G | G | G |  |  |  |
|
| T | T | S |
|  |
Template Predicted Secondary structure |   |
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |
|
|
|  |  |  |  |  |  |  |
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
85 | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . |
  |
  |   |
146 | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | |
. | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |
|
|  |  |  |  |  |  |  |  |  | . |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
M | E | G | A | L | V | E | P | A | A | V | G | M | H | A | . |
A | M | L | A | D | V | K | P | G | K | K | I | I | I | L | G | A | G | C | I | G | L | M | T | L | Q | A | C | K | C | L | G | A | T | E | I | A | V | V | D | V | L | E | K | R | L | A | M | A | E | Q | L | G | A | T | V | V | I | N | G | A | K | E | D |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
E | D | G | A | A | X | I | V | N | P | L | T | A | I | A | X | F | D | I | V | K | Q | E | G | E | K | A | F | V | X | T | A | G | A | S | Q | L | C | K | L | I | I | G | L | A | K | E | E | G | F | R | P | I | V | T | V | R | R | D | E | Q | I | A | L | L | K | D | I | G | A | A | H | V | L | N | E | K | A | P | D |
Template Known Secondary structure |   |
 |  |  | T | T | S | S |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
| S |  |  |  |  | S | S | T | T | S |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
|  |  |  |  |  |  | S |
| G | G | G |  |  |  |  |  |  |  | T |
| S |  |  |  |  | T | T | S | T | T |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |
|
|
|
|  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . |
  |
  |   |
225 | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | |
|
|
. | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | |
|
|
|
|
|
|
Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  | . | . | . |  |  |  |  |
|
|  |  |  |  |  |  |  |
|
|  | . | . | . | . | . | . | . |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
Query Sequence |   |
T | I | A | R | C | Q | Q | F | T | E | D | M | G | A | D | I | V | F | E | T | A | G | S | A | V | T | V | K | Q | A | P | Y | L | V | M | R | G | G | K | I | M | I | V | G | T | V | P | G | D | S | A | I | N | F | . |
. |
. |
L | K | I | N | R | E | V | T | I | Q | T | V | F | R | Y | A | . |
. |
. |
. |
. |
. |
. |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
F | E | A | T | L | R | E | V | X | K | A | E | Q | P | R | I | F | L | D | A | V | T | G | P | L | A | . |
S | A | I | F | N | A | X | P | K | R | A | R | W | I | I | Y | G | R | L | D | P | D | A | T | V | I | R | E | P | G | Q | L | I | F | Q | H | K | H | I | E | G | F | W | L | S | E | W | X | R | Q | F | K | E |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  | S | S |
|  |  |  |  | . |  |  |  |  |  |  | S |
| T | T |
|  |  |  |  |
|
|
| S |
|
| S |
|
|
|
| S |
| T |  |  |  |  |  | S |
|
|  |  |  |  |
|
|  |  |  |  |  |  |  | T |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |
|
|
|  |  |  |  | . |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|
|  |  |  |
|
|  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | |
. | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . |
  |
  |   |
|
|
|
295 | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . |
Predicted Secondary structure |   |
. | . | . |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
Query SS confidence |   |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
. |
. |
. |
N | R | Y | P | V | T | I | E | A | I | S | S | G | R | F | D | V | K | S | M | V | T | H | I | Y | D | Y | R | D | V | Q | Q | A | F | E | E | S | V | N | N | K | R | D | I | I | K | G | V | I | K |
Query Conservation |   |
. | . | . |   |   |
|   |   |   |   |   |
|   |   |   |
|   |
|   |   |   |   |   |
|   |   |   |   |   |
|   |   |   |   |   |
|   |   |   |
|   |   |
|
|   |   |   |
|
|
|
|
|   |
Alig confidence |   |
. | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |
|
|   |   |
|   |
|   |   | . | . | . |
|   |   |   |   |   |
|   |   |   |   |
|
|   | . |   |   |   |   |   |   |   |   | . |
|
|
|
|
|   |
Template Sequence |   |
R | R | G | P | A | I | L | E | A | Q | K | R | F | S | D | G | R | W | S | T | . |
. |
. |
V | T | A | V | V | P | L | A | E | A | I | A | W | V | . |
P | A | E | L | T | K | P | N | . |
G | K | V | F | I | R |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  | T | S | S |
|
|
| . | . | . |
|
|  |  |  |  |  |  |  |  |  |  |  |  | . |  |  |  |  | T | S | S | S | . | S |
|  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
| . | . | . |
|  |  |  |  |  |  |  |  |  |  |  |  |  | . |  |  |  |  |
|
|
|
| . |
|  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
299 | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | |
|
|
. | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | |
. | . | . | . | . | . | . | 340 | |
. | . | . | . | . | . |
  |