|   |
19 | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | |
|
. | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
| . | . |
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Query Sequence |   |
P | F | T | E | E | K | Y | A | T | L | G | R | V | L | R | M | K | . |
. |
P | G | T | R | I | L | D | L | G | S | G | S | G | E | M | L | C | T | W | A | R | D | H | G | I | T | G | T | G | I | D | M | S | S | L | F | T | A | Q | A | K | R | R | A | E | E | L | G | V | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |
|   |   |   |   |   |
|   | . | . |
|
|   |
|
|
|
|
|
|
|
|   |
|   |   |   |   |   |
|
|   |   |   |   |   |   |
|   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . |
Template Conservation |   |
|   |
|
|   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|
|
|
|   |
|
|
|
|
|   |   |
|   |   | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|   |
|
|   |   |   |   |   |   |   |   |
|
|   |
|
|   |   |
|
|
|
|   |
|
Template Sequence |   |
P | V | L | E | Q | C | V | R | E | L | L | R | A | N | L | P | N | I | N | K | C | I | K | V | A | D | L | G | C | A | S | G | P | N | T | L | L | T | V | R | D | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
I | V | Q | S | I | D | K | V | G | Q | L | E | R | P | T | I | Q | I | F | L | N | D | L | F | P | N |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  | S |
|
| T | T | T | T | T |  |  |  |  |  |  |  | T |
|
| S | S |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |
|
| T | T | S |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
34 | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 |
  |
  |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
85 | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Predicted Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Query SS confidence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Query Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
S | E | R | V | H | F | I | H | N | D | A | A | G | Y | V | A | N | E | K | C | D | V | A | A | C | V | G | A | T | W | I | A | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Query Conservation |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Alig confidence |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Conservation |   |
|
|
|
|
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|
|
|
|
|
|   |
|
|
|
|   |   |
|
|
|   |   |   |
|
|   |
|
|
|
|
|
|
|
|
|   |   |
|   |
|   |   |   |   |   |
|   |
|   |
|   |   |   |
Template Sequence |   |
D | F | N | S | V | F | K | L | L | P | S | F | Y | R | K | L | E | K | E | N | G | R | K | I | G | S | C | L | I | G | A | M | P | G | S | F | Y | S | R | L | F | P | E | E | S | M | H | F | L | H | S | C | Y | C | L | Q | W | L | S | Q | V | P | S | G | L | V | T | E | L | I | G | T | N | K | G | S | I | Y | S | S |
Template Known Secondary structure |   |
|  |  |  |  |  |  | T |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
| T | T | S |  |  |  |  |  |
|
| S |
| T | T | S |
|
| S |
| T | T |
|  |  |  |  |  |  |  | S |
| T | T | B |
| S | S | S |
| G | G | G | T | T |
|
|
| T | T | S | T | T |
| S | S |
|
|
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
106 | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . |
  |
  |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
117 | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | 160 | . |
Predicted Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
Query SS confidence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
Query Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
G | G | F | A | G | A | E | E | L | L | A | Q | S | L | K | P | G | G | I | M | L | I | G | E | P | Y | W | R | Q | L | P | A | T | E | E | I | A | Q | A | C | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
G | V | S | S | T |
Query Conservation |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |
|   |   |   |   |
|   |   |   |   |
|   |
|
|
|
|
|   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |
Alig confidence |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
Template Conservation |   |
  |   |
|   |   |   |
|   |   |
|
|   |   |
|
|   |   |
|   |   |   |
|
|   |   |
|
|   |
|
|
|   |
|
|   |
|
|
|   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |
|
|   |
|
|
|   |
|
|
|
|   |
|
|
|   |
|
|
|
|
|
|
Template Sequence |   |
K | A | S | R | L | P | V | Q | K | A | Y | L | D | Q | F | T | K | D | F | T | T | F | L | R | I | H | S | E | E | L | F | S | H | G | R | M | L | L | T | C | I | C | K | G | V | E | L | D | A | R | N | A | I | D | L | L | E | M | A | I | N | D | L | V | V | E | G | H | L | E | E | E | K | L | D | S | F | N | L | P |
Template Known Secondary structure |   |
T | T | S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
| T | T |
| B |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | S | S |
| S | S | T | T | T | T |
|
|
| S |
Template Predicted Secondary structure |   |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
187 | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . |
  |
  |   |
162 | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | |
. | 180 | . | . | . | . | . | |
|
|
|
. | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | |
|
|
|
. | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . |
Predicted Secondary structure |   |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
| . |
|  |  |  |  |  |  | . | . | . | . |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
S | D | F | L | T | L | P | G | L | V | G | A | F | D | D | L | G | . |
Y | D | V | V | E | M | V | . |
. |
. |
. |
L | A | D | Q | E | G | W | D | R | Y | E | A | A | K | W | L | T | M | R | R | W | . |
. |
. |
. |
L | E | A | N | P | D | D | D | F | A | A | E | V | R | A | E | L | N | I | A | P | K | R | Y | V | T |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
| . |   |   |   |   |   |   |   | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|   |
|
|   |
|
|
|   |   |   |
|   |   |   |
|
|
|   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|   |   |   |
|   |   |   |
|
|   |   |
|   |   |
|   |   |
|
|
|   |   |
|   |
|   |
|
|   |
|   |   |   |   |
|   |   |   |   |   |
Template Sequence |   |
V | Y | I | P | S | A | E | E | V | K | C | I | V | E | E | E | G | S | F | E | I | L | Y | L | E | T | F | K | V | L | Y | D | A | G | F | S | H | I | K | A | E | Y | V | A | S | S | V | R | A | V | Y | E | P | I | L | A | S | H | F | G | E | A | I | I | P | D | I | F | H | R | F | A | K | H | A | A | K | V | L | P |
Template Known Secondary structure |   |
B |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
| S |  |  |  |  |  |  |  |  |  |  |  |  | T | T | T | T |
|
|
| T |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| T | T | S |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | G | G |
Template Predicted Secondary structure |   |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
267 | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . |
  |
  |   |
233 | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |
|
|
|
|
|  |  |  |  |  |  |  |  |
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
Y | A | R | E | C | F | G | W | G | V | F | A | L | I | A | R |
Query Conservation |   |
  |   |
|   |   |   |   |   |   |   |   |   |
|   |   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |
|
|   |
|
|
Template Sequence |   |
L | G | K | G | F | Y | N | N | L | I | I | S | L | A | K | K |
Template Known Secondary structure |   |
G | T |
| B |  |  |  |  |  |  |  |  |  |  |  |
|
Template Predicted Secondary structure |   |
 |
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
351 | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . |
  |