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Job DescriptionP0AFG8
Confidence100.00%DateThu Jan 5 11:26:11 GMT 2012
Rank12Aligned Residues597
% Identity22%Templatec3mosA_
PDB info PDB header:transferaseChain: A: PDB Molecule:transketolase; PDBTitle: the structure of human transketolase
Resolution1.75 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   80.........90.........100.........110.........120....... ..130.........140.........150.....
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Query Sequence  RRIRSAIRWNAIMTVLRASKKDLELGGHMASFQSSATIYDVCFNHFFR. . . . ARNEQDGGDLVYFQGHISPGVYARAFLE
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Template Sequence  KDTANRLRISSIQATTAAG. . . . . . SGHPTSCCSAAEIMAVLFFHTMRYKSQDPRNPHNDRFVLSKGHAAPILYAVWAEA
Template Known Secondary structure  T......
S
TTTT
B

TT
TT
TTS
SSGGGT
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   16...20.........30.... .....40.........50.........60.........70.........80.........
 
   156...160.........170.........180.........190.........200.........210.........220.........230.....
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Query Sequence  GRLTQEQLDNFRQEVHGNGLSSYPHPKLMPEFWQFPTVSMGLGPIGAIYQAKFLKYLEHRGLKDTSKQTVYAFLGDGEMD
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Template Sequence  GFLAEAELLNLRKI. . SSDLDGHPVPKQ. . AFTDVATGSLGQGLGAACGMAYTGKY. . . . . . FDKASYRVYCLLGDGELS
Template Known Secondary structure  TSS
GGGGGGTT
T..T
S

SS

TTS..TT
SS


STT
......TS

S

TGGGG
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   90.........100... ......110..... ....120.........130.........140. ........150.........
 
   236...240.........250.........260.........270.........280.........290.........300.........310.....
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Query Sequence  EPESKGAITIATREKLDNLVFVINCNLQRLDGPVTGNGKIINELEGIFEGAGWNVIKVMWGSRWDELLRKDTSGKLIQLM
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Template Sequence  EGSVWEAMAFASIYKLDNLVAILDINRLGQSDPAP. LQHQMDIYQKRCEAFGWHAIIV. . . . . . . . . . . . . . . . . . . . . .
Template Known Secondary structure  STT
TT
SB
SSSB
T.TTT
TT
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   160.........170.........180.........190.... .....200.........210......
 
   316...320.........330.........340.........350.........360.........370.........380.........390.....
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Query Sequence  NETVDGDYQTFKSKDGAYVREHFFGKYPETAALVADWTDEQIWALNRGGHDPKKIYAAFKKAQETKGKATVILAHTIKGY
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Template Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . DGHSVEELCKAFGQAK. . . HQPTAIIAKTFKGR
Template Known Secondary structure  ...............................................TT
S

...SS


TTT
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   217..220.........230.. .......240......
 
   396...400.........410.........420.........430.........440.........450.........460.........470.....
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Query Sequence  GMGDAAEGKNIAHQVKKMNMDGVRHIRDRFNVPVSDADIEKLPYITFPEGSEEHTYLHAQRQKLHGYLPSRQPNFTEKLE
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Template Sequence  GITGVE. . DKESWHGKPLPKNMAEQIIQEI. . . . . . . . . . . . . . . . . . . . . . . . . . . YSQIQSKKKILATPPQEDAPSVD
Template Known Secondary structure  TSTTTT..T
SS
TT



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   247..250.. .......260.........270.... .....280.........290.......
 
   476...480.........490.........500.........510.........520.........530.........540.........550.....
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Query Sequence  LPSLQDFGALLEEQSKEISTTIAFVRALNVMLKNKSIKDRLVPIIADEARTFGMEGLFRQIGIYSPNGQQYTPQDREQVA
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Template Sequence  IANIRMPSLPSYKVGDKIATRKAYGQALAKL. . . GHASDRIIALDGDTKNSTFSEIF. . . . . . . . . . . . . . . . . . . . . . .
Template Known Secondary structure 
S



SS




TT
B

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TTSS
S.......................
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   298.300.........310.........320........ .330.........340.........350.
 
   556...560.........570.........580.........590.........600.........610.........620.........630.....
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Query Sequence  YYKEDEKGQILQEGINELGAGCSWLAAATSYSTNNLPMIPFYIYYSMFGFQRIGDLCWAAGDQQARGFLIGGTSGRTTLN
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Template Sequence  . . KKEHPDRFIECYIAEQNMVSIAVGCATR. . . . . NRTVPFCSTFAAFFTRAFDQIRMAA. . ISESNINLCGSHCGVSIG
Template Known Secondary structure  ..
GGG

S
GG.....G

GGGGGGG..TT

SBSGGG
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   352.......360.........370......... 380.........390.........400.... .....410.........420..
 
   636...640.........650.........660.........670.........680.........690.........700.........710.....
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Query Sequence  GEGLQHEDGHSHIQSLTIPNCISYDPAYAYEVAVIMHDGLERMYGEKQENVYYYITTLNENYHMPAMPEGAEEGIRKGIY
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Template Conservation   

 


   
   
  

 
 
  
 
  
    
  
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Template Sequence  EDGPSQMALEDLAMFRSVPTSTVFYPSDGVATEKAVELAAN. . . . . TKGICFIRTSRPENA. . . . IIYNNNEDFQVGQAK
Template Known Secondary structure  TT
GGG
BSSTSTT


ST.....

S

SS

B....

S
TT



TT

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   423......430.........440.........450.........460... ......470........ .480.........490...
 
   716...720.........730.........740.........750.........760.........770.........780.........790.....
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Query Sequence  KLETIEGSKGKVQLLGSGSILRHVREAAEILAKDYGVGSDVYSVTSFTELARDGQDCERWNMLHPLETPRVPYIAQVMND
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Template Sequence  VVLKSKD. . DQVTVIGAGVTLHEALAAAELLKKE. KINIRVLDPFTIKPLDRK. . . . . . . . LILDSARATKGRILTVEDH
Template Known Secondary structure 

SS..

TTT.T

SS

........TTT
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   494.....500 .........510.........520..... ....530.........540... ......550.........560..
 
   796...800.........810.........820.........830.........840.........850...
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Query Sequence  APAVASTDYMKLFAEQVRTYVPADDYRVLGTDGFGRSDSRENLRHHFEVDASYVVVAA
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Template Sequence  YYEGGI. . . GEAVSSAVVGEP. GITVTHLAVNRVPRSGKPAELLKMFGIDRDAIAQAV
Template Known Secondary structure  STTS...TT
T.T

S



S
TT
S
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   563..... .570.........580 .........590.........600.........610......
 
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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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