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Job DescriptionP0AFG8
Confidence99.32%DateThu Jan 5 11:26:11 GMT 2012
Rank53Aligned Residues482
% Identity13%Templatec2jgdA_
PDB info PDB header:oxidoreductaseChain: A: PDB Molecule:2-oxoglutarate dehydrogenase e1 component; PDBTitle: e. coli 2-oxoglutarate dehydrogenase (e1o)
Resolution2.6 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   195....200.........210.........220......... 230..... ....240.........250... ......260.........
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Query Sequence  MGLGPIGAIYQAKFLKYLEHRGLKDTSKQTVYAFL. . GDGEMD. EPESKGAITIATREKLDN. . LVFVINCNLQRLDGPV
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Template Sequence  LEIVSPVVIGSVRARLDRLD. . . . EPSSNKVLPITIHGDAAVTGQGVVQETLNMSKARGYEVGGTVRIVINNQYCTD. . .
Template Known Secondary structure  TT
TTSS....S

GGG
TTTSTTT

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GGG...
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   323......330.........340.. .......350.........360.........370.........380.........390.....
 
   270.........280.........290.........300.........310.........320.........330.........340.........
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Query Sequence  TGNGKIINELEGIFEGAGWNVIKVMWGSRWDELLRKDTSGKLIQLMNETVDGDYQTFKSKDGAYVREHFFGKYPETAALV
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Template Sequence  . . . . . . . . . . . . IGKMVQAPIFHV. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Template Known Secondary structure  ............GGGTTT

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   411........420..
 
   350.........360.........370.........380. ........390....... ..400.........410
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Query Sequence  ADWTDEQIWALNRGGHDPKKIYAAFKKAQETK. . . GKATVILAHTIKGYGM. . . . . . . . . . . . . . . . GDAAEGKNIAHQV
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Template Sequence  . . . . . . . . . . . . . NADDPEAVAFVTRLALDFRNTFKRDVFIDLVCYRRHQPLMYQKIKKHPTPRKIYADKLEQE. . . . . .
Template Known Secondary structure  .............TT










TTTS

TT......
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   423......430.........440.........450.........460.........470.........480...
 
   411........420.........430.........440.........450.........460.........470.........480.......
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Query Sequence  KKMNMDGVRHIRDRFNVPVSDADIEKLPYITFPEGSEEHTYLHAQRQKLHGYLPSRQPNFTEKLELPSLQDFGALLE. . .
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Template Sequence  KVATLEDATEMVNLY. . . . . . . . . . . . . . . . . . . . . . . RDALDAGDCVVAEWRPMNMHSFTWSPYLNHEWDEEYPNKVEM
Template Known Secondary structure  TSS
.......................TS


TT


GGG
TTGGGSS

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   495....500......... 510.........520.........530.........540.........550.
 
   488.490.........500.........510.........520.......
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Query Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . EQSKEISTTIAFVRALNVMLKNKSIKDRLVPIIADEARTF. . . . . .
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Template Sequence  KRLQELAKRISTVPEAVEMQSRVAKIYGDRQAMAAGEKLFDWGGAENLAYATLVDE. . . GIPVRLSGEDSGRGTFFHRHA
Template Known Secondary structure  TT


TTS


TTSS
B
TT...T

TTTTT
TTS



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   552.......560.........570.........580.........590.........600....... ..610.........620........
 
   528.530.........540.........550.........560.........570.........580.........590.........600..
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Query Sequence  . . . . . GMEGLFRQIGIYSPNGQQYTPQDREQVAYYKEDEKGQILQEGINELGAGCSWLAAATSYSTNNLPMIPFYIYYSM
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Template Sequence  VIHNQSNGSTYTPLQHIHNGQGAF. . . . . . . . . . . . . . . . . RVWDSVLSEEAVLAFEYGYATA. . . EPRTLTIWEAQFGD
Template Known Secondary structure  S
SSSS

GGG
S
TT


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TTS
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   629630.........640.........650.. .......660.........670.... .....680........
 
   603.... ..610......... 620.........630.........640... ......650.........660.........670.....
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Query Sequence  FGFQR. . . IGDLCWAAGDQQ. . ARGFLIGGTSGRTTLNGEGLQHED. . GHSHIQSLTIPNCISYDPAYAYEVAVIMHDGL
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Template Sequence  FANGAQVVIDQFISSGEQKWGRMCGLVMLLPH. . . GYEGQGPEHSSARLERYLQLCAEQNMQVCVPSTPAQVYHMLRRQA
Template Known Secondary structure  GGGGGTTTT






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SSS
TTSS


T

TT




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   689690.........700.........710.........720 .........730.........740.........750.........760.....
 
   676...680.........690.........700.........710.........720........ .730.........740.........750...
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Query Sequence  ERMYGEKQENVYYYITTLNENYHMPAMPEGAEEGIRKGIYKLETIEGSKGKVQ. . LLGSGSILRHVREAAEILAKDYGVG
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Template Sequence  LRGMRR. . . . PLVVMSPKSLLRHPLAVSSLEELANGTFLPAIGEIDELDPKGVKRVVMCSGKVYYDL. LEQRRKNN. QHD
Template Known Secondary structure  SS


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SGGGG
TT

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S


S


GGG


TT.TT.

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   766...770. ........780.........790.........800.........810.........820........ .830...... ...
 
   754.....760.........770.........780.........790.........800.........810....... ..820.........830..
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Query Sequence  SDVYSVTSFTELARDGQDCERWNMLHPLETPRVPYIAQVMNDAPAVASTDYMKLFAEQVRTYVP. ADDYRVLGTDGFGRS
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Template Sequence  VAIVRIEQLYPFPHKAMQEV. . . LQQFAHVKDFVWCQEEPLNQ. . . . . . GAWYCSQHHFREVIPFGASLRYAGRPASASP
Template Known Secondary structure 
S

...GGGTT

TTS......TTTTS
TT



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   840.........850......... 860.........870......... 880.........890.........900.........910
 
   833.
Predicted Secondary structure 

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Query Sequence  DS
Query Conservation   
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Template Conservation 
 
Template Sequence  AV
Template Known Secondary structure  S
Template Predicted Secondary structure 

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   911.
 
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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
© Structural Bioinformatics Group, Imperial College, London
Lawrence Kelley, Benjamin Jefferys 
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