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Job DescriptionP0AFG8
Confidence100.00%DateThu Jan 5 11:26:11 GMT 2012
Rank8Aligned Residues657
% Identity22%Templatec1tkcA_
PDB info PDB header:transferaseChain: A: PDB Molecule:transketolase; PDBTitle: specificity of coenzyme binding in thiamin diphosphate2 dependent enzymes: crystal structures of yeast3 transketolase in complex with analogs of thiamin4 diphosphate
Resolution2.70 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   77..80.........90.........100.........110.........120.........130.... .....140.........150...
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Query Sequence  ELERRIRSAIRWNAIMTVLRASKKDLELGGHMASFQSSATIYDVCFNHFFRARNEQDG. . . GDLVYFQGHISPGVYARAF
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Template Sequence  DIDKLAVSTIRILAVDTVSKAN. . . . . . SGHPGAPLGMAPAAHVLWSQMRMNPTNPDWINRDRFVLSNGHAVALLYSMLH
Template Known Secondary structure  T......
S

T



TT
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TT

SSGGG
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   6...10.........20....... ..30.........40.........50.........60.........70.........
 
   154... ..160.........170.........180.........190.........200.........210........ .220.........
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Query Sequence  LEGR. LTQEQLDNFRQEVHGNGLSSYPHPKLMPEFWQFPTVSMGLGPIGAIYQAKFLKYLEHRGLK. . . DTSKQTVYAFL
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Template Sequence  LTGYDLSIEDLKQFRQL. . GSRTPGHPEFEL. . PGVEVTTGPLGQGISNAVGMAMAQANLAATYNKPGFTLSDNYTYVFL
Template Known Secondary structure  TTSS

TTTST..T
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TTS..TT

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STT
BTTB





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   80.........90...... ...100........ .110.........120.........130.........140.........150.....
 
   230.........240.........250.........260.........270.........280.........290.........300.........
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Query Sequence  GDGEMDEPESKGAITIATREKLDNLVFVINCNLQRLDGPVTGNGKIINELEGIFEGAGWNVIKVMWGSRWDELLRKDTSG
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Template Sequence  GDGCLQEGISSEASSLAGHLKLGNLIAIYDDNKITIDGATSISFD. . EDVAKRYEAYGWEVLYVENG. . . . . . . . . . . . .
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STT
TT
SB
SSSB

..S
T
TTT.............
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   156...160.........170.........180.........190.........200 .........210.........220
 
   310.........320.........330.........340.........350.........360.........370.........380.........
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Query Sequence  KLIQLMNETVDGDYQTFKSKDGAYVREHFFGKYPETAALVADWTDEQIWALNRGGHDPKKIYAAFKKAQETKGKATVILA
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Template Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . NEDLAGIAKAIAQAKLSKDKPTLIKM
Template Known Secondary structure  ......................................................TT
TT
TTS
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   221........230.........240......
 
   390.........400.........410.........420....... ..430.........440..... ....450.........460...
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Query Sequence  HTIKGYGMGDAAEGKNIAHQVKKMNMDGVRHIRDRFNV. PVSDADIEKLPYITFPEG. . . . . SEEHTYLHAQRQKLHGYL
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Template Sequence  TTTIGYGSLHAG. . . SHSVHGAPLKADDVKQLKSKFGFNPDKSFVVPQEVYDHYQKTILKPGVEANNKWNKLFSEYQKKF
Template Known Secondary structure 

TTTTSTTTT...SGGGGSS


TS
TT

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TS
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   247..250........ .260.........270.........280.........290.........300.........310.........320...
 
   464.....470.........480.........490 .........500.........510.........520.........530.........540
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Query Sequence  PSRQPNFTEKLELPSLQDFGALLEEQS. . . KEISTTIAFVRALNVMLKNKSIKDRLVPIIADEARTFGMEGLFRQIGIYS
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Template Sequence  PELGAELARRLSGQLPANWESKLPTYTAKDSAVATRKLSETVLEDV. . . YNQLPELIGGSADLTPSNLT. . . . . . . . . . .
Template Known Secondary structure  T


TTGGGGS



TTS

...TT
TTSS
T
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   324.....330.........340.........350.........360......... 370.........380.........
 
   541........550.........560.........570.........580.........590.........600.........610.........620
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Query Sequence  PNGQQYTPQDREQVAYYKEDEKGQILQEGINELGAGCSWLAAATSYSTNNLPMIPFYIYYSMFGFQRIGDLCWAAGDQQA
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Template Sequence  . . . RWKEALDFQPPSSGSGNYSGRYIRYGIREHAMGAIMNGISA. . . . FGANYKPYGGTFLNFVSYAAGAVRLSA. . LSG
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TT

BB

GGGSS
BTT



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   390.........400.........410.........420.........430 .........440.........450....... ..460
 
   621........630.........640.........650.........660.........670.........680.........690.........700
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Query Sequence  RGFLIGGTSGRTTLNGEGLQHEDGHSHIQSLTIPNCISYDPAYAYEVAVIMHDGLERMYGEKQENVYYYITTLNENYHMP
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Template Sequence  HPVIWVATHDSIGVGEDGPTHQPIETLAHFRSLPNIQVWRPADGNEVSAAYKNSLESKHTP. . . . SIIALSRQNLP. . . .
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SGGG
TT
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   461........470.........480.........490.........500.........510.........520. ........530..
 
   701........710.........720.........730.........740.........750.........760.........770.........780
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Query Sequence  AMPEGAEEGIRKGIYKLETIEGSKGKVQLLGSGSILRHVREAAEILAKDYGVGSDVYSVTSFTELARDGQDCERWNMLHP
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Template Sequence  QLEGSSIESASKGGYVLQDVAN. . PDIILVATGSEVSLSVEAAKTLAAK. NIKARVVSLPDFFTFDKQPLEYRLSVLP. .
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TT

TTS


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TT.T


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   533......540.........550.... .....560.........570......... 580.........590.........600.......
 
   781........790.........800.........810.........820.........830.........840.........850.........
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Query Sequence  LETPRVPYIAQVMNDAPAVASTDYMKLFAEQVRTYVPADDYRVLGTDGFGRSDSRENLRHHFEVDASYVVVAALGELAK.
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Template Sequence  . . . . . . . . . . . . . DNVPIMSVEVLATTCWGKY. . . . . . . AHQSFGIDRFGASGKAPEVFKFFGFTPEGVAERAQKTIAFY
Template Known Secondary structure  .............SSS
SS
GGGGGGT.......
S

S



S
T
S
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   608.610.........620...... ...630.........640.........650.........660.......
 
   860.........870.
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Query Sequence  RGEIDKKVVADA
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Template Conservation 
           
Template Sequence  KGDKLISPLKKA
Template Known Secondary structure  TT




TT


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   668.670.........
 
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Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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