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Job DescriptionP27302
Confidence100.00%DateThu Jan 5 11:43:48 GMT 2012
Rank10Aligned Residues599
% Identity27%Templatec3mosA_
PDB info PDB header:transferaseChain: A: PDB Molecule:transketolase; PDBTitle: the structure of human transketolase
Resolution1.75 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   1........10.........20.........30.........40.........50.........60.........70.........80
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Query Sequence  MSSRKELANAIRALSMDAVQKAKSGHPGAPMGMADIAEVLWRDFLKHNPQNPSWADRDRFVLSNGHGSMLIYSLLHLTGY
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Template Conservation     
   
  

            

 
  

      

           
    


 
 
 

     

     
 
Template Sequence  LQALKDTANRLRISSIQATTAAGSGHPTSCCSAAEIMAVLFFHTMRYKSQDPRNPHNDRFVLSKGHAAPILYAVWAEAGF
Template Known Secondary structure  T
S
TTTT
B

TT
TT
TTS
SSGGGTTS
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   12.......20.........30.........40.........50.........60.........70.........80.........90.
 
   81........90.........100.........110.........120.........130.........140.........150.........160
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Query Sequence  DLPMEELKNFRQLHSKTPGHPEVGYTAGVETTTGPLGQGIANAVGMAIAEKTLAAQFNRPGHDIVDHYTYAFMGDGCMME
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Template Conservation  .     
         
 
 
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Template Sequence  . LAEAELLNLRKISSDLDGHPVP. KQAFTDVATGSLGQGLGAACGMAYTGKYFDKA. . . . . . . . . SYRVYCLLGDGELSE
Template Known Secondary structure  .S
GGGGGGTT
TT
S

SS

T.TSTT
SS


STT
TS

.........S

TGGGGS
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   92.......100.........110... ......120.........130.........140..... ....150.........160
 
   161........170.........180.........190.........200 .........210.........220.........230.........
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Query Sequence  GISHEVCSLAGTLKLGKLIAFYDDNGISIDGHVEGWFTDD. TAMRFEAYGWHVIRDIDGHDAASIKRAVEEARAVTDKPS
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Template Conservation 
   


  
    
  

 
 
 
   
                    
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Template Sequence  GSVWEAMAFASIYKLDNLVAILDINRLGQSDPAPLQHQMDIYQKRCEAFGWHAI. IVDGHSVEELCKAFGQAK. . . HQPT
Template Known Secondary structure  TT
TT
SB
SSSB
TTTT
TT
.TT
S

...SS
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   161........170.........180.........190.........200.........210.... .....220.........230.. ....
 
   240.........250.........260.........270.........280.........290.........300.........310.........
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Query Sequence  LLMCKTIIGFGSPNKAGTHDSHGAPLGDAEIALTREQLGWKYAPFEIPSEIYAQWDAKEAGQAKESAWNEKFAAYAKAYP
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Template Conservation   
   
 

 
    
     
              
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Template Sequence  AIIAKTFKGRGITGVEDKESWHGKPLPKNMAEQIIQEIYSQIQ. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Template Known Secondary structure 

TTTTSTTTTT
SS
TT



T

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   237..240.........250.........260.........270.........
 
   320.........330.........340.........350.........360.........370.........380.........390.........
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Query Sequence  QEAAEFTRRMKGEMPSDFDAKAKEFIAKLQANPAKIASRKASQNAIEAFGPLLPEFLGGSADLAPSNLTLWSGSKAINED
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Template Sequence  SKKKILATPPQEDAPSVDIANIRMPSLPSYKVGDKIATRKAYGQALAKLGHASDRIIALDGDTKNST. . . . . FSEIFKKE
Template Known Secondary structure 






B










S



SS




TT
B


TTSS
.....S
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   280.........290.........300.........310.........320.........330.........340...... ...350....
 
   400.........410.........420.........430.........440.........450.........460.........470.........
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Query Sequence  AAGNYIHYGVREFGMTAIANGISLHGGFLPYTSTFLMFVEYARNAVRMAALMKQRQVMVYTHDSIGLGEDGPTHQPVEQV
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Template Sequence  HPDRFIECYIAEQNMVSIAVGCATRNRTVPFCSTFAAFFTRAFDQIRMAAISESNINLCGSHCGVSIGEDGPSQMALEDL
Template Known Secondary structure 
GGG

S
GGG

GGGGGGGTT

SBSGGG
TT
GGG
BSS
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   355....360.........370.........380.........390.........400.........410.........420.........430....
 
   480.........490.........500.........510.........520.........530.........540.........550.........
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Query Sequence  ASLRVTPNMSTWRPCDQVESAVAWKYGVERQDGPTALILSRQNLAQQERTEEQLANIARGGYVLKDCAGQPELIFIATGS
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Template Conservation    
  

 
 
  
 
  
    
  
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Template Sequence  AMFRSVPTSTVFYPSDGVATEKAVELAANT. KGICFIRTSRPENAIIYNNNEDFQ. . VGQAKVVLKS. KDDQVTVIGAGV
Template Known Secondary structure  TSTT


ST
.
S

SS

B

S
TT



..TT



.SS

T
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   435....440.........450.........460.... .....470.........480........ .490........ .500.........510
 
   560.........570.........580.........590.........600. ..... ...610.........620....... ..630...
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Query Sequence  EVELAVAAYEKLTAEGVKARVVSMPSTDAFDKQDAAYRESVL. PKAVT. ARVAVEAGIADYWYKYVGLNG. . . . AIVGMT
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Template Conservation   
  

 

  
   

   

    
 


   
          

 


    

 
  
   
           
  
Template Sequence  TLHEALAAAELLKKEKINIRVLDPFTIKPLDRKLILDSARATKGRILTVEDHYYEGGIGEAVSSAVVGEPGITVTHLAVN
Template Known Secondary structure  TTT

SS

TTTSTTSTT
TT

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   511........520.........530.........540.........550.........560.........570.........580.........590
 
   634.....640.........650.........660
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Query Sequence  TFGESAPAELLFEEFGFTVDNVVAKAK
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Template Conservation   
  

    
    

  
 
   

Template Sequence  RVPRSGKPAELLKMFGIDRDAIAQAVR
Template Known Secondary structure  S



S
TT
ST
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   591........600.........610.......
 
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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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