Job Description P27302 Confidence 100.00% Date Thu Jan 5 11:43:48 GMT 2012 Rank 8 Aligned Residues 646 % Identity 47% Template c1tkcA_ PDB info PDB header:transferase Chain: A: PDB Molecule:transketolase; PDBTitle: specificity of coenzyme binding in thiamin diphosphate2 dependent enzymes: crystal structures of yeast3 transketolase in complex with analogs of thiamin4 diphosphate Resolution 2.70 Å

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		1	.	.	.	.	.	.	.		.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.
Predicted Secondary structure										.
Query SS confidence										.
Query Sequence		M	S	S	R	K	E	L	A	.	N	A	I	R	A	L	S	M	D	A	V	Q	K	A	K	S	G	H	P	G	A	P	M	G	M	A	D	I	A	E	V	L	W	R	D	F	L	K	H	N	P	Q	N	P	S	W	A	D	R	D	R	F	V	L	S	N	G	H	G	S	M	L	I	Y	S	L	L	H	L	T	G
Query Conservation										.
Alig confidence										.																																				.
Template Conservation																																														.
Template Sequence		F	T	D	I	D	K	L	A	V	S	T	I	R	I	L	A	V	D	T	V	S	K	A	N	S	G	H	P	G	A	P	L	G	M	A	P	A	A	H	V	L	W	S	Q	.	M	R	M	N	P	T	N	P	D	W	I	N	R	D	R	F	V	L	S	N	G	H	A	V	A	L	L	Y	S	M	L	H	L	T	G
Template Known Secondary structure																									T		S																		T	.					T	T		T	T		T	T							S	S	G	G	G											T	T
Template Predicted Secondary structure																																														.
Template SS confidence
		4	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.		.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.
		80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		Y	D	L	P	M	E	E	L	K	N	F	R	Q	L	H	S	K	T	P	G	H	P	E	V	G	Y	T	A	G	V	E	T	T	T	G	P	L	G	Q	G	I	A	N	A	V	G	M	A	I	A	E	K	T	L	A	A	Q	F	N	R	P	G	H	D	I	V	D	H	Y	T	Y	A	F	M	G	D	G	C	M	M
Query Conservation
Alig confidence																										.
Template Conservation																										.
Template Sequence		Y	D	L	S	I	E	D	L	K	Q	F	R	Q	L	G	S	R	T	P	G	H	P	E	F	.	E	L	P	G	V	E	V	T	T	G	P	L	G	Q	G	I	S	N	A	V	G	M	A	M	A	Q	A	N	L	A	A	T	Y	N	K	P	G	F	T	L	S	D	N	Y	T	Y	V	F	L	G	D	G	C	L	Q
Template Known Secondary structure		S	S								T	T	T	S	T	T		S			S	S			T	.	T	S	T	T			S				S	T	T																						B	T	T	B
Template Predicted Secondary structure																										.
Template SS confidence
		83	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.		.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.
		160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.		.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.
Predicted Secondary structure																																																												.
Query SS confidence																																																												.
Query Sequence		E	G	I	S	H	E	V	C	S	L	A	G	T	L	K	L	G	K	L	I	A	F	Y	D	D	N	G	I	S	I	D	G	H	V	E	G	W	F	T	D	D	T	A	M	R	F	E	A	Y	G	W	H	V	I	R	D	I	D	.	G	H	D	A	A	S	I	K	R	A	V	E	E	A	R	A	V	T	D	K	P
Query Conservation																																																												.
Alig confidence																																																												.
Template Conservation
Template Sequence		E	G	I	S	S	E	A	S	S	L	A	G	H	L	K	L	G	N	L	I	A	I	Y	D	D	N	K	I	T	I	D	G	A	T	S	I	S	F	D	E	D	V	A	K	R	Y	E	A	Y	G	W	E	V	L	Y	V	E	N	G	N	E	D	L	A	G	I	A	K	A	I	A	Q	A	K	L	S	K	D	K	P
Template Known Secondary structure		S													T	T		T	T									S	B		S	S	S	B							S										T							T	T	T	T	T													T	T		T	T	S
Template Predicted Secondary structure
Template SS confidence
		162	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.
		239	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.		280	.	.	.	.	.	.	.	.	.	290	.	.	.	.			.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.
Predicted Secondary structure																																											.																.	.
Query SS confidence																																											.																.	.
Query Sequence		S	L	L	M	C	K	T	I	I	G	F	G	S	P	N	K	A	G	T	H	D	S	H	G	A	P	L	G	D	A	E	I	A	L	T	R	E	Q	L	G	W	.	K	Y	A	P	F	E	I	P	S	E	I	Y	A	Q	W	.	.	D	A	K	E	A	G	Q	A	K	E	S	A	W	N	E	K	F	A	A	Y	A
Query Conservation																																											.																.	.
Alig confidence																	.																										.																.	.
Template Conservation																	.
Template Sequence		T	L	I	K	M	T	T	T	I	G	Y	G	S	L	H	.	A	G	S	H	S	V	H	G	A	P	L	K	A	D	D	V	K	Q	L	K	S	K	F	G	F	N	P	D	K	S	F	V	V	P	Q	E	V	Y	D	H	Y	Q	K	T	I	L	K	P	G	V	E	A	N	N	K	W	N	K	L	F	S	E	Y	Q
Template Known Secondary structure										T	T	T	T	S	T	T	.	T	T	S	G	G	G	G	S	S															T	S		T	T			S														T
Template Predicted Secondary structure																	.
Template SS confidence
		242	.	.	.	.	.	.	.	250	.	.	.	.	.	.		.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320
		316	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.							.	.	.
Predicted Secondary structure																																																																									.	.	.	.	.	.
Query SS confidence																																																																									.	.	.	.	.	.
Query Sequence		K	A	Y	P	Q	E	A	A	E	F	T	R	R	M	K	G	E	M	P	S	D	F	D	A	K	A	K	E	F	I	A	K	L	Q	A	N	P	A	K	I	A	S	R	K	A	S	Q	N	A	I	E	A	F	G	P	L	L	P	E	F	L	G	G	S	A	D	L	A	P	S	N	.	.	.	.	.	.	L	T	L
Query Conservation																																																																									.	.	.	.	.	.
Alig confidence																													.	.	.	.																																									.	.	.	.	.	.
Template Conservation																													.	.	.	.
Template Sequence		K	K	F	P	E	L	G	A	E	L	A	R	R	L	S	G	Q	L	P	A	N	W	E	S	K	L	P	.	.	.	.	T	Y	T	A	K	D	S	A	V	A	T	R	K	L	S	E	T	V	L	E	D	V	Y	N	Q	L	P	E	L	I	G	G	S	A	D	L	T	P	S	N	L	T	R	W	K	E	A	L	D
Template Known Secondary structure				S													T				T	T	G	G	G	G	S		.	.	.	.				T	T	S																		T	T		T	T						S	S						T				T	T			B
Template Predicted Secondary structure																													.	.	.	.
Template SS confidence
		321	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.					.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.
		390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.		.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.
Predicted Secondary structure																																							.
Query SS confidence																																							.
Query Sequence		W	S	G	S	K	A	I	N	E	D	A	A	G	N	Y	I	H	Y	G	V	R	E	F	G	M	T	A	I	A	N	G	I	S	L	H	G	G	.	F	L	P	Y	T	S	T	F	L	M	F	V	E	Y	A	R	N	A	V	R	M	A	A	L	M	K	Q	R	Q	V	M	V	Y	T	H	D	S	I	G	L	G	E
Query Conservation																																							.
Alig confidence																																							.
Template Conservation
Template Sequence		F	Q	P	P	S	S	G	S	G	N	Y	S	G	R	Y	I	R	Y	G	I	R	E	H	A	M	G	A	I	M	N	G	I	S	A	F	G	A	N	Y	K	P	Y	G	G	T	F	L	N	F	V	S	Y	A	A	G	A	V	R	L	S	A	L	S	G	H	P	V	I	W	V	A	T	H	D	S	I	G	V	G	E
Template Known Secondary structure		B			G	G	G	S	S		B	T	T								S																	T	T																										T											S	G	G	G		T
Template Predicted Secondary structure
Template SS confidence
		397	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.
		469	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		D	G	P	T	H	Q	P	V	E	Q	V	A	S	L	R	V	T	P	N	M	S	T	W	R	P	C	D	Q	V	E	S	A	V	A	W	K	Y	G	V	E	R	Q	D	G	P	T	A	L	I	L	S	R	Q	N	L	A	Q	Q	E	R	T	E	E	Q	L	A	N	I	A	R	G	G	Y	V	L	K	D	C	A	G
Query Conservation
Alig confidence																																																																.	.														.
Template Conservation																																																																.	.														.
Template Sequence		D	G	P	T	H	Q	P	I	E	T	L	A	H	F	R	S	L	P	N	I	Q	V	W	R	P	A	D	G	N	E	V	S	A	A	Y	K	N	S	L	E	S	K	H	T	P	S	I	I	A	L	S	R	Q	N	L	P	Q	L	E	G	S	S	.	.	I	E	S	A	S	K	G	G	Y	V	L	Q	D	.	V	A
Template Known Secondary structure		T		T	T	S	S		S	S						T	T	S	T	T								S															S	S									S	S						T	T			.	.					T	T	S							.		S
Template Predicted Secondary structure																																																																.	.														.
Template SS confidence
		477	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.			.	540	.	.	.	.	.	.	.	.	.	550	.		.	.
		549	550	.	.	.	.	.	.	.	.	.	560	.	.	.	.	.	.	.	.	.	570	.	.	.	.	.	.	.	.	.	580	.	.	.	.	.	.	.	.	.	590	.	.	.	.	.	.	.	.	.				600	.	.	.	.	.	.	.	.	.	610	.	.	.	.	.	.	.	.	.	620	.	.	.	.	.
Predicted Secondary structure																																																					.	.	.
Query SS confidence																																																					.	.	.
Query Sequence		Q	P	E	L	I	F	I	A	T	G	S	E	V	E	L	A	V	A	A	Y	E	K	L	T	A	E	G	V	K	A	R	V	V	S	M	P	S	T	D	A	F	D	K	Q	D	A	A	Y	R	E	S	.	.	.	V	L	P	K	A	V	T	A	R	V	A	V	E	A	G	I	A	D	Y	W	Y	K	Y	V	G	L
Query Conservation																																																					.	.	.
Alig confidence																																																					.	.	.																		.	.	.	.	.	.	.
Template Conservation																																																																									.	.	.	.	.	.	.
Template Sequence		N	P	D	I	I	L	V	A	T	G	S	E	V	S	L	S	V	E	A	A	K	T	L	A	A	K	N	I	K	A	R	V	V	S	L	P	D	F	F	T	F	D	K	Q	P	L	E	Y	R	L	S	V	L	P	D	N	V	P	I	M	S	V	E	V	L	A	T	T	C	W	G	.	.	.	.	.	.	.	K	Y
Template Known Secondary structure		S		S							T																T	T									S							T	S									S		S	S	S							S	S		G	G	G	G	G	.	.	.	.	.	.	.	G	T
Template Predicted Secondary structure																																																																									.	.	.	.	.	.	.
Template SS confidence
		554	.	.	.	.	.	560	.	.	.	.	.	.	.	.	.	570	.	.	.	.	.	.	.	.	.	580	.	.	.	.	.	.	.	.	.	590	.	.	.	.	.	.	.	.	.	600	.	.	.	.	.	.	.	.	.	610	.	.	.	.	.	.	.	.	.	620	.	.	.	.								.	.
		626	.	.	.	630	.	.	.	.	.	.	.	.	.	640	.	.	.	.	.	.	.	.	.	650	.	.	.	.	.	.	.	.	.	660	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		N	G	A	I	V	G	M	T	T	F	G	E	S	A	P	A	E	L	L	F	E	E	F	G	F	T	V	D	N	V	V	A	K	A	K	E	L	L
Query Conservation
Alig confidence
Template Conservation
Template Sequence		A	H	Q	S	F	G	I	D	R	F	G	A	S	G	K	A	P	E	V	F	K	F	F	G	F	T	P	E	G	V	A	E	R	A	Q	K	T	I
Template Known Secondary structure			S							S					S										T		S
Template Predicted Secondary structure
Template SS confidence
		627	.	.	630	.	.	.	.	.	.	.	.	.	640	.	.	.	.	.	.	.	.	.	650	.	.	.	.	.	.	.	.	.	660	.	.	.	.