|   |
58 | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | |
|
|
. | . | . | . | . | . | . | 130 | . | . | . | . |
Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
T | T | E | T | V | G | L | V | V | G | D | V | S | D | P | F | F | G | A | M | V | K | A | V | E | Q | V | A | Y | H | T | G | N | F | L | L | I | G | N | G | Y | H | N | E | Q | K | E | R | Q | A | I | E | Q | L | I | R | H | R | C | A | A | L | V | V | H | . |
. |
. |
A | K | M | I | P | D | A | D | L | A | S | L |
Query Conservation |   |
  |   |   |   |
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |   |   |
|
|
|
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|   |   |   |   |
|   |   |   |
|   |   |   |   |
|   |   |   |   |   |
|   |   |   |
|   |   |   |
|   |   |
|
|   |   |   |
|
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
K | E | V | K | I | G | M | A | I | D | D | L | R | L | E | R | W | Q | K | D | R | D | I | F | V | K | K | A | E | S | L | G | A | K | V | F | V | Q | S | A | N | G | N | E | E | T | Q | M | S | Q | I | E | N | M | I | N | R | G | V | D | V | L | V | I | I | P | Y | N | G | Q | V | L | S | N | V | V | K | E | A | K |
Template Known Secondary structure |   |
|
|
|  |  |  |  |  |  | S |
| S |
| S |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|  |  |  |  |  |  |
| S | S |
|  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
| S |  |  |  |  |
|
| S | S | T | T | S |
|  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
1 | . | . | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 |
  |
  |   |
135 | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | |
. | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . |
Predicted Secondary structure |   |
 |  |
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
M | K | Q | M | P | G | M | V | L | I | N | R | I | L | P | G | F | E | N | R | C | I | A | L | D | D | R | Y | G | A | W | L | A | T | R | H | L | I | Q | Q | G | H | T | R | I | G | Y | . |
L | C | S | N | H | S | I | S | D | A | E | D | R | L | Q | G | Y | Y | D | A | L | A | E | S | G | I | A | A | N | D | R | L |
Query Conservation |   |
  |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   | . |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
Q | E | G | I | K | V | L | A | Y | D | R | M | I | N | D | A | D | I | D | F | Y | I | S | F | D | N | E | K | V | G | E | L | Q | A | K | A | L | V | D | I | V | P | Q | G | N | Y | F | L | M | G | G | S | P | V | D | N | N | A | K | L | F | R | A | G | Q | M | K | V | L | K | P | Y | V | D | S | G | K | I | K | V |
Template Known Secondary structure |   |
 | T | T |
|  |  |  |  |  | S | S |
|
|
| S | S |
|
| S |  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| S | S |  |  |  |  |  |  |  |
|
| T | T |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | S |  |  |  |
Template Predicted Secondary structure |   |
 |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
81 | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 |
  |
  |   |
|
|
|
|
214 | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | |
|
. | 280 | . | . | . | . | |
. | . |
Predicted Secondary structure |   |
. | . | . | . |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|  |  |  |  | . | . |  |  |
|
|
|
| . |
|  |
Query SS confidence |   |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
| . |
|
|
Query Sequence |   |
. |
. |
. |
. |
V | T | F | G | E | P | D | E | S | G | G | E | Q | A | M | T | E | L | L | G | R | G | R | N | F | T | A | V | A | C | Y | N | D | S | M | A | A | G | A | M | G | V | L | N | D | N | G | I | D | V | P | G | E | I | S | L | I | G | F | D | D | V | L | V | S | . |
. |
R | Y | V | R | P | R | . |
L | T |
Query Conservation |   |
. | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|   |   |   |   |   |   |
|
|   |
|
|   |
|
|
|   |
|   |   |   |   |   | . | . |   |   |   |   |
|   | . |
|
|
Alig confidence |   |
. | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
| . |
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |
|
|   |   |   |   |
|   |   |
|   |
|   |   |   |
|
|   |   |   |
|   | . | . |   |   |   |
|   |
|   |
|   |
|   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |
Template Sequence |   |
V | G | D | Q | W | V | D | G | W | L | P | E | N | A | L | K | I | M | E | N | A | L | T | A | N | N | N | K | I | D | A | V | V | A | S | N | D | A | T | A | G | G | A | I | Q | A | L | S | A | Q | G | L | . |
. |
S | G | K | V | A | I | S | G | Q | D | A | D | L | A | G | I | K | R | I | A | A | G | T | Q | T | M |
Template Known Secondary structure |   |
 |  |  |  |  |
| G | G | G |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | T |
|
|
|  |  |  |  | S | S |  |  |  |  |  |  |  |  |  |  |  |  | T | T | T |
| . | . | T | T | T | S |  |  |
|
|
| S |
|
|  |  |  |  |  |  |  |  |  | T | S | S |
|  |
Template Predicted Secondary structure |   |
 |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
| . | . |
|
|
|
|  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
161 | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | |
|
. | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . |
  |
  |   |
287 | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
T | V | R | Y | P | I | V | T | M | A | T | Q | A | A | E | L | A | L | A | L | A | D | N | R | P | L | P | E | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
I | T | N | V | F | S | P | T | L | V | R | R | H | S | V |
Query Conservation |   |
|
|   |   |   |   |   |   |   |
|   |   |
|
|   |   |
|   |   |   |
|   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |
|   |   |   |
|
|   |
|   |
|
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|
|   |
|   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|
|
|
Template Sequence |   |
T | V | Y | K | P | I | T | L | L | A | N | T | A | A | E | I | A | V | E | L | G | N | G | Q | E | P | K | A | D | T | T | L | N | N | G | L | K | D | V | P | S | R | L | L | T | P | I | D | V | N | K | N | N | I |
Template Known Secondary structure |   |
 |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
|
|
|
| S |  |  |  |  |
| S | S | S |  |  |  |  |  |  |  |
|
|  |  |  |  | T | T | T | T |
Template Predicted Secondary structure |   |
 |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |
|
|
|
|
|
|
|
|  |  |  |
|
|
|  |  |  |
|  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
239 | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . |
  |