|   |
2 | . | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . |
Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | T | I | K | D | V | A | R | L | A | G | V | S | V | A | T | V | S | R | V | I | N | N | S | P | K | A | S | E | A | S | R | L | A | V | H | S | A | M | E | S | L | S | Y | H | P | N | A | N | A | R | A | L | A | Q | Q | T | T | E | T | V | G | L | V | V | G | D | V | S | D | P | F | F | G | A | M | V | K | A | V |
Query Conservation |   |
  |
|
|   |
|
|
|   |   |
|
|
|
|   |   |
|
|
|
|
|
|
|   |   |   |   |
|
|   |   |
|
|   |
|
|   |   |   |
|   |   |
|
|
|   |
|
|   |   |
|   |   |
|   |   |   |   |   |   |   |
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|
|
|   |
|
|
|   |   |   |
|
|
|   |   |
|
|
|
|
|
|
|   |   |   |   |
|
|   |   |
|
|   |
|
|   |   |   |
|   |   |
|
|
|   |
|   | . | . | . | . | . |
|   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
G | T | L | A | S | I | A | A | K | L | G | I | S | R | T | T | V | S | N | A | Y | N | R | P | E | Q | L | S | A | E | L | R | Q | R | I | L | D | T | A | E | D | M | G | Y | A | G | A | . |
. |
. |
. |
. |
I | G | V | L | L | T | E | D | L | T | Y | A | F | E | . |
. |
. |
D | M | A | S | V | D | F | L | A | G | V |
Template Known Secondary structure |   |
T |  |  |  |  |  |  |  |  |  | T | S |
|  |  |  |  |  |  |  |  |  |
| G | G | G | S |
|  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
|
|  | . | . | . | . | . |  |  |  |  |  | S | S |
| T | T |  |  |  |  | . | . | . | S |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
| . | . | . | . | . |
|  |  |
|
|
|
|
|  |  |  |  |  |
| . | . | . |
|
|  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | |
|
|
|
|
. | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | |
|
|
. | . | . | . | . | . | . | . | . | 80 | . |
  |
  |   |
82 | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
E | Q | V | A | Y | H | T | G | N | F | L | L | I | G | N | G | Y | H | N | E | Q | K | E | R | Q | A | I | E | Q | L | I | R | H | R | C | A | A | L | V | V | H | A | K | M | I | P | D | A | D | L | A | S | L | M | K | Q | M | P | G | M | V | L | I | N | R | I | L | P | G | F | E | N | R | C | I | A | L | D | D | R |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |
Template Sequence |   |
A | Q | A | A | G | D | T | Q | L | T | L | I | . |
P | A | S | P | A | S | S | V | D | H | V | S | A | Q | Q | L | V | N | N | A | A | V | D | G | V | V | I | Y | S | V | A | K | G | D | P | H | I | D | A | I | R | A | R | G | L | P | A | V | I | A | D | Q | P | A | R | E | E | G | M | P | F | I | A | P | N | N | R |
Template Known Secondary structure |   |
 |  |  | S | S | S |
|  |  |  |  |  | . |  |
|
|
|
| T | T |
|
|  |  |  |  |  |  |  |  |  | T |
|
|
| S |
|  |  |  |  | S |
|
| T | T |
|  |  |  |  |  |  |  |  |  | T |
|
|  |  |  |  | S | S |
|
| S |
| T | T |
|
|  |  |  |  |
|  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|  |  |  | . |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
96 | . | . | . | 100 | . | . | . | . | . | . | . | |
. | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . |
  |
  |   |
162 | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | |
. | . | . | . | . | . | . | . | 220 | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
| . |  |  |  |  |  |
|
|
|
|
|  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
Y | G | A | W | L | A | T | R | H | L | I | Q | Q | G | H | T | R | I | G | Y | L | C | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
S | N | H | S | I | S | D | A | E | D | R | L | Q | G | Y | Y | D | A | L | A | E | S | G | I | A | A | N | D | . |
R | L | V | T | F | G | E | P | D | E | S | G |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   | . |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
K | A | I | A | P | A | A | Q | A | L | I | D | A | G | H | R | K | I | G | I | L | S | I | R | L | D | R | A | N | N | D | G | E | V | T | R | E | R | L | E | N | A | Q | Y | Q | V | Q | R | D | R | V | R | G | A | M | E | V | F | I | E | A | G | I | D | P | G | T | V | P | I | M | E | C | W | I | N | N | R | Q | H |
Template Known Secondary structure |   |
 |  | T |  |  |  |  |  |  |  |  |  | T | T |
|
| S |  |  |  |  |  |  |
|
| S | S | S |
|
|
|  |  |
|
|  |  |  |  |  | T |
|
|
| T | T |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
|
| G | G | G | S |
|  |  |  |  | S | S |
|
|  |  |  |
Template Predicted Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
175 | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . |
  |
  |   |
224 | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
G | E | Q | A | M | T | E | L | L | G | R | G | R | N | F | T | A | V | A | C | Y | N | D | S | M | A | A | G | A | M | G | V | L | N | D | N | G | I | D | V | P | G | E | I | S | L | I | G | F | D | D | V | L | V | S | R | Y | V | R | P | R | L | T | T | V | R | Y | P | I | V | T | M | A | T | Q | A | A | E | L | A |
Query Conservation |   |
  |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|   |   |   |   |   |   |
|
|   |
|
|   |
|
|
|   |
|   |   |   |   |   |   |   |   |   |
|   |
|
|
|
|   |   |   |   |   |   |   |
|   |   |
|
|   |   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |
|
|   |   |   |   |
|   |   |
|   |   |   |   |   |   |
|   |   |   |
|   |   |
|
|   |
|
|   |
|
|
|   |
|   |   |   |   |   |   |   | . | . |
|   |
|
|
|
|   |   |   |   |   |   |   |
|   |   |
|
|   |   |
|
Template Sequence |   |
N | F | E | V | A | K | E | L | L | E | T | H | P | D | L | T | A | V | L | C | T | V | D | A | L | A | F | G | V | L | E | Y | L | K | S | V | G | K | S | A | P | A | D | L | S | L | T | G | F | D | G | T | H | M | A | L | A | . |
. |
R | D | L | T | T | V | I | Q | P | N | K | L | K | G | F | K | A | G | E | T | L |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |
| T | T |
|
|  |  |  |  | S | S |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
| T | T | T | T |
|  |  |  |  |  |  |
|
|  |  |  |  |  | . | . | T | T |
|
|  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|  |  |  |  |  |
| . | . |
|
|
|
|  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
255 | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | |
|
. | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . |
  |
  |   |
304 | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 |
Predicted Secondary structure |   |
 |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
L | A | L | A | D | N | R | P | L | P | E | I | T | N | V | F | S | P | T | L | V | R | R | H | S | V | S |
Query Conservation |   |
  |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|
|   |
|   |
|
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |
|   |   |   |   |   |   |   | . |   |   |   |
|   |   |   |
|   |   |
|   |
|
|   |
Template Sequence |   |
L | K | M | I | D | K | E | Y | V | E | P | . |
E | V | E | L | E | T | S | F | H | P | G | S | T | V | A |
Template Known Secondary structure |   |
 |  |  |  | T | T |
|
|
|
| S | . |  |  |  |  |
|
|  |  |  |
|
| S |
|
|
|
Template Predicted Secondary structure |   |
 |  |  |  |
|
|
|
|
|
|
| . |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
333 | . | . | . | . | . | . | 340 | . | . | . | |
. | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . |
  |