|   |
15 | . | . | . | . | 20 | . | . | . | . | |
|
|
|
|
. | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
Predicted Secondary structure |   |
|  |  |  |  |  |
|
|
|
| . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |
|  |  |  |  |
|
|
|
|
|  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Query Sequence |   |
A | R | V | V | F | P | D | A | L | D | . |
. |
. |
. |
. |
Q | R | V | L | K | A | A | Q | Y | L | H | Q | Q | G | L | A | T | P | I | L | V | A | N | P | F | E | L | R | Q | F | A | L | S | H | G | V | A | M | D | G | L | Q | V | I | D | P | H | G | N | L | A | M | R | E | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Query Conservation |   |
|
|
|
|   |   |
|
|   |
| . | . | . | . | . |   |   |
|
|   |
|
|   |   |
|   |   |
|
|   |
|   |   |
|
|
|
|   |   |   |   |
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|
|
|   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . |
Alig confidence |   |
|
|
|
|
|
|
| . |
|
| . | . | . | . | . |
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . |
Template Conservation |   |
  |
|
|
|
|
|   | . |
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|   |   |   |   |   |   |   |   |
|
|
|
|
|   |   |   |
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |
Template Sequence |   |
L | R | F | A | L | T | P | . |
G | E | P | A | G | I | G | P | D | L | C | . |
. |
L | L | L | A | R | S | A | Q | P | H | P | L | I | A | I | A | S | R | T | L | L | Q | E | R | A | G | Q | L | G | L | A | I | D | L | K | D | V | S | P | A | A | W | P | E | R | P | A | K | A | G | Q | L | Y | V | W | D | T | P | L |
Template Known Secondary structure |   |
|
|  |  |  |  |
| . |
| S | T | T | S | S |  |  |  |  |  | . | . |  |  | G | G | G | S |
|
| S | S |
|  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  | T |
|
|
|  |  |  |  |
| B | T | T | B |
|
|
| S |
|
|
| T | T |  |  |  |  |  |  |
|
|
|
Template Predicted Secondary structure |   |
|  |  |  |  |  |
| . |
|
|
|
|
|
|
|  |  |  |  | . | . |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
1003 | . | . | . | . | . | . | |
1010 | . | . | . | . | . | . | . | . | . | 1020 | |
|
. | . | . | . | . | . | . | . | . | 1030 | . | . | . | . | . | . | . | . | . | 1040 | . | . | . | . | . | . | . | . | . | 1050 | . | . | . | . | . | . | . | . | . | 1060 | . | . | . | . | . | . | . | . | . | 1070 | . | . | . | . | . | . | . | . | . |
  |
  |   |
|
|
|
|
|
|
|
79 | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | |
|
|
|
|
|
|
. | . | . | 140 | . | . | . | . |
Predicted Secondary structure |   |
. | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . | . |  |  |
|
|
|
|
|
|
Query SS confidence |   |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
Query Sequence |   |
. |
. |
. |
. |
. |
. |
. |
E | F | A | H | R | W | L | A | R | A | G | E | K | T | P | P | D | A | L | E | K | L | T | D | P | L | M | F | A | A | A | M | V | S | A | G | K | A | D | V | C | I | A | G | N | L | S | S | T | A | N | V | L | R | A | G | L | R | . |
. |
. |
. |
. |
. |
. |
I | I | G | L | Q | P | G | C |
Query Conservation |   |
. | . | . | . | . | . | . |   |   |   |   |   |   |   |   |
|   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|   |   |
|   |
|
|   |
|
|
|
|   |   |   |   |
|   |   |   |
|   |
|
|
|   | . | . | . | . | . | . | . |   |
|
|   |   |   |
|   |
Alig confidence |   |
. | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |
|   |
|
|   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . |   |   |
|
|   |   |
|   |   |
|   |   |   |
|   |
|
|
|   |
|
| . | . |
|
|   |
|
|
|   |
|   |   |
|
|   |   |   |   |
|
|
|
|   |
|   |   |
|   |
|   |
Template Sequence |   |
A | A | P | V | R | P | G | Q | L | D | R | A | N | A | A | Y | V | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
L | E | T | L | T | R | A | G | Q | G | C | L | D | G | H | F | A | G | X | I | T | . |
. |
A | P | V | H | K | G | V | I | N | E | A | G | I | P | F | S | G | H | T | E | F | L | A | D | L | T | H | T |
Template Known Secondary structure |   |
S | S |
|
| B | T | T | B |
|
| G | G | G |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  | T | S |
| S |  |  |  |  | . | . |
|
|
|
|  |  |  |  |  |  | T | T |
|
|
| S |
|  |  |  |  |  |  |  |  | T | T |
|
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  | . | . |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
1080 | . | . | . | . | . | . | . | . | . | 1090 | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
. | . | . | 1100 | . | . | . | . | . | . | . | . | . | 1110 | . | . | . | . | . | . | . | |
|
. | . | 1120 | . | . | . | . | . | . | . | . | . | 1130 | . | . | . | . | . | . | . | . | . | 1140 | . | . | . | . | . |
  |
  |   |
145 | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | |
|
|
. | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | |
. | . | . | . | . | . | . | . | 200 | . | . | . | . | |
|
|
|
. | . | . | . | . | 210 | . | . | . | . | . | . |
Predicted Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  | . | . | . |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . |  |
|
|
|
|
|
|  |  |  |  |  |
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
K | T | L | S | S | I | F | L | M | L | P | Q | Y | S | G | P | A | L | G | . |
. |
. |
F | A | D | C | S | V | V | P | Q | P | T | A | A | Q | L | A | D | I | A | L | A | S | A | E | T | W | R | A | . |
I | T | G | E | E | P | R | V | A | M | L | S | F | . |
. |
. |
. |
S | S | N | G | S | A | R | H | P | C | V | A |
Query Conservation |   |
  |   |   |
|   |
|   |
|   |   |   |   |   |   |   |   |   |   |   | . | . | . |   |
|
|   |
|
|
|
|   |
|   |   |
|   |
|   |   |
|
|   |   |
|   |   |   |
|   |   | . |
|   |   |   |   |
|
|
|
|
|
|
|   | . | . | . | . |
|   |   |
|
|   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |
|   |   |   |   | . | . |   |   |
|   |   |   |   |   |
|   |
|
|   |
|   |   |
|   |   |   |
|
|   |
|   |
|   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |
|
|   |   |
|
|
|
|
|
|   |
|
|
|
|
|
|
|
|
|   |   |
|   |
|
|   |   |
Template Sequence |   |
A | Q | V | V | X | X | L | A | T | . |
. |
R | G | L | R | V | A | L | A | T | T | H | L | P | L | R | E | V | A | D | A | I | S | D | E | R | L | T | R | V | A | R | I | L | H | A | D | L | R | D | K | F | G | I | A | H | P | R | I | L | V | C | G | L | N | P | H | A | G | E | G | G | H | L | G | R | E | E | I | E |
Template Known Secondary structure |   |
S |
|
|  |  |  |  |  |  | . | . | T | T |  |  |  |  |  | S | S |
| S | S |
|  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | S |
|
| S | S |
|  |  |  |  |  |
| S | S | G | G | G | G | G | G | G | T | S |
| S |  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|
|  |  |  |
|
| . | . |
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
1146 | . | . | . | 1150 | . | . | . | . | |
|
. | . | . | . | . | 1160 | . | . | . | . | . | . | . | . | . | 1170 | . | . | . | . | . | . | . | . | . | 1180 | . | . | . | . | . | . | . | . | . | 1190 | . | . | . | . | . | . | . | . | . | 1200 | . | . | . | . | . | . | . | . | . | 1210 | . | . | . | . | . | . | . | . | . | 1220 | . | . | . |
  |
  |   |
217 | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
N | V | Q | Q | A | T | E | I | V | R | E | R | A | P | K | L | V | V | D | G | E | L | Q | F | D | A | A | F | V | P | E | V | A | A | Q | K | A | P | A | S | P | L | Q | G | K | A | N | V | M | V | F | P | S | L | E | A | G | N | I | G | Y | K | I | A | Q | R | L | G | G | Y | R | A | V | G | P | L | I | Q | G | L |
Query Conservation |   |
  |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |
|
|
|   |   |   |   |
|   |
|   |   |   |   |   |
|   |   |
|   |   |   |
|   |
|   |
|   |
|
|
|
|
|   |
|   |
|   |
|
|
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|   |
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
Template Conservation |   |
|
|   |
|
|   |   |   |
|   |   |   | . | . |
|
|   |   |   |
|
|   |   |
|
|   |   |
|   |   |   |   | . | . | . | . | . | . | . | . | . | . |   |   |   |   |
|   |   |
|
|
|
|
|
|
|
|   |
|   |   |
|   |
|   |
|   |   |   |
|
| . | . | . | . |   |
|   |
|
|
Template Sequence |   |
V | I | E | P | C | L | E | R | L | R | G | E | . |
. |
G | L | D | L | I | G | P | L | P | A | D | T | L | F | T | P | K | H | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
L | E | H | C | D | A | V | L | A | X | Y | H | D | Q | G | L | P | V | L | K | Y | K | G | F | G | A | A | V | N | . |
. |
. |
. |
V | T | L | G | L |
Template Known Secondary structure |   |
T |  |  |  |  |  |  |  |  |  |  | T | . | . | T |
|  |  |  |  |  |  |
|  |  |  |  | S | S |  |  |  | . | . | . | . | . | . | . | . | . | . |  | T | T |
| S |  |  |  |  | S | S |  |  |  |  |  |  |  |  |  |  |  | T | T | T |
|
|  |  | . | . | . | . |  |  |  | T | S |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |
| . | . |
|
|  |  |  |  |
|
|
|
|  |  |  |
|
|
|
|
| . | . | . | . | . | . | . | . | . | . |  |  |  |
|
|  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  | . | . | . | . |  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
1224 | . | . | . | . | . | 1230 | . | . | . | . | . | |
|
. | . | . | . | 1240 | . | . | . | . | . | . | . | . | . | 1250 | . | . | . | |
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | 1260 | . | . | . | . | . | . | . | . | . | 1270 | . | . | . | . | . | . | . | . | . | 1280 | . | . | |
|
|
|
. | . | . | . | . |
  |
  |   |
297 | . | . | 300 | . | |
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|  |  | . | . | . | . | . | . | . | . | . | . |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | A | P | M | H | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
D | L | S | R | G | C | S | V | Q | E | I | I | E | L | A | L | V | A | A | V | P | R | Q | T |
Query Conservation |   |
  |   |
|
|   | . | . | . | . | . | . | . | . | . | . |   |   |
|
|   |   |
|   |   |   |
|   |   |   |   |
|   |
|   |   |   |
|   |   |
Alig confidence |   |
|
|
|
|
| . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |
|
|
|
|   |
|
|
|
|
|   |
|
|
|
|   |
|   |
|   |   |   |
|   |   |   |
|
|   |   |
|   |   |   |   |   |   |
Template Sequence |   |
P | I | I | R | T | S | V | D | H | G | T | A | L | D | L | A | G | S | G | R | I | D | S | G | S | L | Q | V | A | L | E | T | A | Y | Q | X | A | A | S |
Template Known Secondary structure |   |
S | S |
|  |  |  |  | S | S |
|
|
| G | G | G | T | T | S |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
1288 | . | 1290 | . | . | . | . | . | . | . | . | . | 1300 | . | . | . | . | . | . | . | . | . | 1310 | . | . | . | . | . | . | . | . | . | 1320 | . | . | . | . | . | . |
  |