|   |
22 | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | |
|
|
|
|
|
. | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | |
|
|
|
|
|
|
|
|
|
. | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | |
|
Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
| . | . | . | . | . | . |
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
| . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|  |  |  |
|
|
|
|
|
|  |  |  |  |  | . | . |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
Query Sequence |   |
L | Y | E | R | S | H | A | I | R | L | C | L | L | A | A | L | S | . |
. |
. |
. |
. |
. |
G | E | S | V | F | L | L | G | P | P | G | I | A | K | S | L | I | A | R | R | L | K | F | A | F | Q | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
N | A | R | A | F | E | Y | L | M | T | R | F | S | T | P | E | E | V | F | . |
. |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   | . | . | . | . | . | . |
|   |   |
|
|
|   |
|
|
|
|
|
|
|
|   |
|
|   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   | . | . |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
Template Conservation |   |
|   |
|
|
|   |
|
|   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|
|
|   |
|   |   |
|
|
|
|
|   |
|
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
I | P | F | R | E | D | I | L | R | D | A | A | I | A | I | R | Y | F | V | K | N | E | V | K | F | S | N | L | F | L | G | L | T | G | T | G | K | T | F | V | S | K | Y | I | F | N | E | I | E | E | V | K | K | E | D | E | E | Y | K | D | V | K | Q | A | Y | V | N | C | R | E | V | G | G | T | P | Q | A | V | L | S |
Template Known Secondary structure |   |
| T | T |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
|
|
|  |  |  |  |  |  |
| T | T | S | S |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | S | S | S | S | T | T |
|  |  |  |  |  |  |  |  |  |  |
| S |
|  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|  |  |
|
|
|  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
32 | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . |
  |
  |   |
|
|
|
|
|
|
|
|
84 | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | |
. | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . |
Predicted Secondary structure |   |
. | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
| . |
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |
|
|  |  |  |  |
|
|
|
|  |  |  |  |  |
|
Query SS confidence |   |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
G | P | L | S | I | Q | A | L | K | D | E | G | R | Y | E | R | L | T | S | G | Y | L | P | E | A | E | I | V | F | L | D | E | I | W | K | . |
A | G | P | A | I | L | N | T | L | L | T | A | I | N | E | R | Q | F | R | N | G | A | H | V | E | K | I | P | M | R | L | L | V | A | A | S |
Query Conservation |   |
. | . | . | . | . | . | . | . |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|
|
|
|   |   | . |   |   |   |   |   |   |   |   |
|
|   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|
|
Alig confidence |   |
. | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |
|   |   |
|
Template Sequence |   |
S | L | A | G | K | L | T | G | F | S | V | P | K | H | G | I | N | L | G | E | Y | I | D | K | I | K | N | G | T | R | N | I | R | A | I | I | Y | L | D | E | V | D | T | L | V | K | R | R | G | G | D | I | V | L | Y | Q | L | L | R | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
S | D | A | N | I | S | V | I | M | I | S |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |
| S |
|
|
| S | S | S | S |
| T |  |  |  |  |  |  |  |  |  |  |  | S | S | S |
|  |  |  |  |  |  | T | T |  |  |  |  |  | S | T | T | S |  |  |  |  |  |  |  |  | T | . | . | . | . | . | . | . | . | . | . | S | S | S |
|  |  |  |  |  |  |
|
Template Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |
| . | . | . | . | . | . | . | . | . | . |
|
|
|
|  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
112 | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | |
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | . | . | 180 | . |
  |
  |   |
155 | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
N | E | L | P | E | A | D | S | S | L | E | A | L | Y | D | R | M | L | I | R | L | W | L | D | K | V | Q | D | K | A | N | F | R | S | M | L | T | S | Q | Q | D | E | N | D | N | P | V | P | D | A | L | Q | V | T | D | E | E | Y | E | R | W | Q | K | E | I | G | E | I | T | L | P | D | H | V | F | E | L | I | F | M |
Query Conservation |   |
  |   |   |
|   |   |   |   |   |   |   |   |
|   |
|
|
|   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |
|   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
Template Sequence |   |
N | D | I | N | V | R | D | Y | M | E | P | R | V | L | S | S | L | G | P | S | V | I | F | K | P | Y | D | A | E | Q | L | K | F | I | L | S | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
K | Y | A | E | Y | G | L | I | K | G | T | Y | D | D | E | I | L | S | Y | I | A | A |
Template Known Secondary structure |   |
S | S | T | T | T | T | T | T | S |
|  |  |  |  |  | T |
|
|
|  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  | T | S |
| T | T | S |
|
| S |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|  |  |  |  |  |  |
|
|  |  |  |  |
|
|
|
|
|  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
182 | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . |
  |
  |   |
235 | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |
|
|
|
|  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
L | R | Q | Q | L | D | K | L | P | D | A | P | Y | V | S | D | R | R | W | K | K | A | I | R | L | L | Q | A | S | A | F | F | S | G | R | S | A | V | A | P | V | D | L | I | L | L | K | D | C | L | W | Y | D |
Query Conservation |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |   |   |   |   |
|   |   |   |   |
|   |   |   |
|
|   |   |
|   |   |   |
|   |   |   |
|   |
|   |
|   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
Template Sequence |   |
I | S | A | K | E | H | G | D | A | . |
. |
. |
. |
. |
. |
. |
. |
. |
R | K | A | V | N | L | L | F | R | A | A | Q | L | A | S | G | G | G | I | I | R | K | E | H | V | D | K | A | I | V | D | Y | E | Q | E |
Template Known Secondary structure |   |
 |  |  | T | T |
|
|
|  | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | S | S | S |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |
|
|
|
|
|  | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
240 | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
. | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . |
  |