|   |
43 | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |
|
|
|
|  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
L | N | Q | E | V | L | A | P | G | A | A | F | Q | P | R | T | Y | P | K | V | D | I | L | N | V | I | L | D | G | E | A | E | Y | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
R | D | S | E | G | N | H | V | Q | A | S | A | G | E | A | L | L | L | S | T | Q | P | G | V | S | Y | S | E | H |
Query Conservation |   |
  |
|
|
|   |
|   |
|
|   |
|
|   |   |
|
|
|
|
|   |
|
|
|
|
|
|
|   |
|   |
|   |
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |
|
|   |
|
|   |   |   |
|   |   |
|
|
|
|   |
|
|
|
|   |
|
|   |
|
|
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
Template Conservation |   |
  |   |
|   |   |
|   |
|   |   |
|   |
|
|   |   |   | . |   |
|   |   |
|   |
|
|   |
|
|   |
|   |   |
|   |
|   |
|
|
|   |
|
|
|   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |
|   |   |
|
|
|   |   |
|
|
|
|   | . | . |   |   |   |   |   |
Template Sequence |   |
M | I | R | H | T | I | R | P | K | G | L | L | L | P | G | F | S | . |
N | A | P | K | L | I | F | V | A | Q | G | F | G | I | R | G | I | A | I | P | G | C | A | E | T | Y | Q | T | D | L | R | A | F | K | D | Q | H | Q | K | I | R | P | F | R | E | G | D | L | L | V | V | P | A | G | V | . |
. |
S | H | W | M | Y |
Template Known Secondary structure |   |
 |  |  |  |  |  |
| T | T |  |  |  |  |  |  |  |  | . | S | S |
|  |  |  |  |  |  |  |
|  |  |  |  |  |  |
|
| T | T |
|
|
|
|  |  |  |
|
|
|
|
|
|  |  |  |
|
|
|  |  |  |  | T | T |  |  |  |  |  |
| T | T |
| . | . |
|  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |
| . |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
| . | . |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
65 | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | |
. | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | |
|
. | . | . | 140 | . |
  |
  |   |
105 | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | |
. | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Predicted Secondary structure |   |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|  |  |  |
|
| . |
|
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Query Sequence |   |
N | L | S | K | D | K | P | L | T | R | M | Q | L | W | L | D | A | C | P | Q | R | E | . |
N | P | L | I | Q | K | L | A | L | N | M | G | K | Q | Q | L | I | A | S | P | E | G | A | M | G | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Query Conservation |   |
|   |   |   |   |   |   |   |   |   |
|
|
|
|
|   |
|   |   |   |   |   | . |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Alig confidence |   |
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Conservation |   |
| . |   |
|   |   |   |   |
|   |
|   |   |   |
|   |   |
|   |   |
|
|
|
|   |   |   |   |   |
|   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|   |   |   |
|   |   |
|
|   |
|   |   |   |   |   |   |
|
|   |   |   |   |   |   |   |
Template Sequence |   |
N | . |
R | G | Q | S | D | L | V | L | I | V | F | A | D | T | R | N | V | A | N | Q | I | D | P | Y | L | R | K | F | Y | L | A | G | R | P | E | Q | V | E | R | G | V | E | E | K | S | G | N | I | F | S | G | F | A | D | E | F | L | E | E | A | F | Q | I | D | G | G | L | V | R | K | L | K | G | E | D | D | E | R |
Template Known Secondary structure |   |
 | . |
| S | S | S |
|  |  |  |  |  |  |  |  | S | S | S | T | T |
|
| S |
| S | S |
|
|  |  |  | S | S | S |
|
|
|
|
| S | S | T | T |
|
|
|
|
|
| T | T | T | T | S |
|  |  |  |  |  |  |  |  | T |
|
|  |  |  |  |  |  |  |  | T | T | T |
|
| S |
Template Predicted Secondary structure |   |
 | . |
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
149 | |
150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . |
  |
  |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
152 | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | |
. | . | . |
Predicted Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
| . |
|
|
|
Query SS confidence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
Query Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
S | L | Q | L | R | Q | Q | V | W | L | H | H | I | V | L | D | K | G | E | S | A | N | F | Q | L | . |
H | G | P |
Query Conservation |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   | . |   |   |   |
Alig confidence |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
Template Conservation |   |
|   |
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |
|   |
|
|   |   |   |
|   |
|   |   |
|
|
|   |   |
|
|   |
|   |   |
|
Template Sequence |   |
D | R | I | V | Q | V | D | E | D | F | E | V | L | L | P | E | T | I | C | T | L | R | L | K | Q | N | I | G | R | S | E | R | A | D | V | F | N | P | R | G | G | R | I | S | T | A | N | Y | H | T | L | P | I | L | R | Q | V | R | L | S | A | E | R | G | V | L | Y | S | N | A | M | V | A | P | H | Y | T | V | N | S |
Template Known Secondary structure |   |
T | T |  |  |  |
|
| S | S |
|
| T | T | T | T |
|
| G | G | G | S |
|
|  |  |  |
| S | T | T | S |
|
| S |  |  |  | T | T | T |  |  |  |  |  |  |
| T | T | T | S | T | T |  |  |  |  | T |
|  |  |  |  |  |  |  |
| T | T |
|  |  |  |  |  |  |  | S | S |
|
Template Predicted Secondary structure |   |
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|  |  |  |
|
|
|  |  |  |
|
|  |  |  |  |  |  |  |  |  |
|
|
|  |  |
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . |
  |
  |   |
180 | . | . | . | . | . | . | . | . | . | 190 | . | . | |
|
|
|
|
. | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | |
. | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . |
|
|
|
|
|
|
|  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|  |  |  |  |  |  |
| . |
|
|  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
Query Sequence |   |
R | A | Y | L | Q | S | I | H | G | K | F | H | A | . |
. |
. |
. |
. |
L | T | H | H | E | E | K | A | A | L | T | C | G | D | G | A | F | I | R | D | E | A | N | I | T | L | V | A | D | . |
S | P | L | R | A | L | L | I |
Query Conservation |   |
  |   |   |
|   |
|   |   |
|   |   |   |
| . | . | . | . | . |   |   |   |   |   |   |   |   |   |
|   |   |
|
|   |   |   |
|   |   |   |   |   |
|   |
|   |
|   | . |   |   |
|   |   |
|
|
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|
|   |   |
|   |   |
|   |
|   |
|   |
|
|   |   |   |
|   |   |   |   |   |   |   |
|   |   |
|
|
|   |
|
|
|   |
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |
|   |
|
Template Sequence |   |
H | S | V | M | Y | A | T | R | G | N | A | R | V | Q | V | V | D | N | F | G | Q | S | V | F | D | G | E | V | R | E | G | Q | V | L | M | I | P | Q | N | F | V | V | I | K | R | A | S | D | R | G | F | E | W | I | A | F |
Template Known Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| T | T | S |
|  |  |  |  |  |  |  |  | T | T |
|  |  |  |  |
| T | T |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
344 | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . |
  |