|   |
325 | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | |
|
|
|
|
. | . | . | . | 390 | . | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|  |  |  |
|
|
|
|
|  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  | . | . | . | . | . |  |  |  |  |  |
|
|
|
|
|
|  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
P | R | Q | Q | Y | G | N | D | D | R | P | L | Q | S | G | T | I | E | V | D | N | V | S | F | A | Y | R | D | D | N | L | V | L | K | N | I | N | L | S | V | P | S | R | N | F | V | A | L | V | G | H | T | G | S | G | K | S | T | L | A | S | . |
. |
. |
. |
. |
L | L | M | G | Y | Y | P | L | T | E | G | E | I | R |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|
|
|   |
|   |   |   |   |   |   |
|   |   |
|   |
|   |
|   |   |
|
|   |   |   |
|   |
|   |
|
|   |
|
|
|
|
|   |   | . | . | . | . | . |
|
|   |
|   |   |   |   |   |   |
|   |
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   | . | . | . | . | . | . |   |   |
|
|   |
|   |   |   |
|   |   |
|   |   |   |
|
|   |
|   |
|
|
|
|
|
|
|
|   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
A | D | R | H | T | E | P | H | T | P | R | E | P | A | G | W | L | E | L | N | G | V | T | R | . |
. |
. |
. |
. |
. |
N | N | L | D | N | L | D | V | R | F | P | L | G | V | M | T | S | V | T | G | V | S | G | S | G | K | S | T | L | V | S | Q | A | L | V | D | A | L | A | A | H | F | G | Q | G | S | A | R | L | G |
Template Known Secondary structure |   |
T |
|
|
|
|
|
|
|
|
|
|
|
| S |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . | T | T |  |  |  |  |  |  |  |  |  |  | S | S |  |  |  |  |  |  | S | T | T | S | S |  |  |  |  |  | T | T |  |  |  |  |  |  |  |  |  | S |
|
|
|  |  |  |  |
|
Template Predicted Secondary structure |   |
 |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
487 | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . | . | . | . | . | 510 | |
|
|
|
|
|
. | . | . | . | . | . | . | . | . | 520 | . | . | . | . | . | . | . | . | . | 530 | . | . | . | . | . | . | . | . | . | 540 | . | . | . | . | . | . | . | . | . | 550 | . | . | . | . | . | . | . | . | . | 560 |
  |
  |   |
400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Predicted Secondary structure |   |
 |
|
|
|
|  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Query Sequence |   |
L | D | G | R | P | L | S | S | L | S | H | S | A | L | R | Q | G | V | A | M | V | Q | Q | D | P | V | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Query Conservation |   |
|   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |
|   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Alig confidence |   |
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Conservation |   |
  |   |   |   |   |
|   | . | . | . | . | . | . | . | . | . |   |
|   |   |
|   |
|   |
|
|   |   |   |   |
|
|   |   |   |
|   |   |   |   |   |
|   |
|
|   |
|
|   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |
|   |
|   |   |   |
|   |   |   |   |   |   |
|   |
|
Template Sequence |   |
G | D | L | A | Q | I | T | . |
. |
. |
. |
. |
. |
. |
. |
. |
R | L | V | R | V | D | Q | K | P | I | G | R | T | P | R | S | N | M | A | T | Y | T | G | L | F | D | Q | V | R | K | L | F | A | A | T | P | L | A | K | K | R | G | Y | N | A | G | R | F | S | F | N | V | K | G | G | R | C | E | H | C | Q | G | E | G |
Template Known Secondary structure |   |
S | S | G | G | G |
|
| . | . | . | . | . | . | . | . | . |  |  |  |  |  |
| S | S |
| S |
| S | S | T | T |
|
|  |  |  |  |  | T | T |  |  |  |  |  |  |  | T | T | S | S | T |  |  |  |  | S |
|
|
| T | T | S | S |
| S | S | S | S | S | S | B |
| S | S | S | T | T |
|
|
Template Predicted Secondary structure |   |
|
|
|  |  |
|
| . | . | . | . | . | . | . | . | . |
|  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
578 | . | 580 | . | . | . | . | |
|
|
|
|
|
|
|
|
. | . | . | . | . | 590 | . | . | . | . | . | . | . | . | . | 600 | . | . | . | . | . | . | . | . | . | 610 | . | . | . | . | . | . | . | . | . | 620 | . | . | . | . | . | . | . | . | . | 630 | . | . | . | . | . | . | . | . | . | 640 | . | . | . | . | . | . | . | . |
  |
  |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
426 | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | |
. | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
| . |
|  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
Query SS confidence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
V | L | A | D | T | F | L | A | N | V | T | L | G | R | D | I | . |
S | E | E | R | V | W | Q | A | L | E | T | V | Q | L | A | E | L | A | R | S | M | S | D | G | I | Y | T | P |
Query Conservation |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|   |   |
|
|   |
|
|
|   |   |   |   |   |   | . |   |   |   |   |   |   |   |   |
|   |   |   |   |
|   |   |   |
|   |   |
|   |   |
|   |   |
|   |
Alig confidence |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . |
|
|
|
|
Template Conservation |   |
  |   |   |
|   |   |
|   |   |   |   |   |   |   |   |
|   |
|   |   |   |   |   |
|   |   |   |   |   |   |   |   |
|   |
|   |
|   |   |
|
|   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |
|
|
| . | . | . | . | . | . | . | . | . | . |   |   |   |   |
Template Sequence |   |
W | V | M | V | P | S | V | Y | A | P | C | P | V | C | H | G | T | R | Y | N | A | E | T | L | E | V | E | Y | R | G | K | N | I | A | D | V | L | A | L | T | V | D | E | A | H | D | F | F | A | D | E | S | A | I | F | R | A | L | D | T | L | R | E | V | G | L | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
G | Y | L | R |
Template Known Secondary structure |   |
 |  |  |
|
|
|
|  |  |  |
| T | T | T | S | S | S |
| B |
| T | T | G | G | G |
|
| S | S | S |
|
|  |  |  |  |  | T |
| B |  |  |  |  |  |  |  | T | T | T |
|  |  |  |  |  |  |  |  |  |  |  |  |  | T |
| . | . | . | . | . | . | . | . | . | . | T | T | S | B |
Template Predicted Secondary structure |   |
 |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
| . | . | . | . | . | . | . | . | . | . |
|  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
649 | 650 | . | . | . | . | . | . | . | . | . | 660 | . | . | . | . | . | . | . | . | . | 670 | . | . | . | . | . | . | . | . | . | 680 | . | . | . | . | . | . | . | . | . | 690 | . | . | . | . | . | . | . | . | . | 700 | . | . | . | . | . | . | . | . | . | 710 | . | . | . | . | |
|
|
|
|
|
|
|
|
|
. | . | . | . |
  |
  |   |
470 | . | . | . | . | . | . | . | . | . | 480 | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | |
|
|
. | . | . | 500 | . | . | . | . | . | . | . | . | . | 510 | . | . | . | . | . | . | . | . | . | 520 | . | . | . | |
. | . | . | . | . | . | 530 | . | . | . | . | . | . | . | . | . | 540 | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
| . | . | . |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . |
|
|
|  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
L | G | E | Q | G | N | N | L | S | V | G | Q | K | Q | L | L | A | L | A | R | V | L | V | E | T | P | Q | . |
. |
. |
I | L | I | L | D | E | A | T | A | S | I | D | S | G | T | E | Q | A | I | Q | H | A | L | A | A | V | R | . |
E | H | T | T | L | V | V | I | A | H | R | L | S | T | I | V | D | A | D | T | I | L |
Query Conservation |   |
|   |   |   |
|   |   |
|
|
|
|
|   |
|
|
|   |
|
|
|
|
|   |   |   |   |   | . | . | . |
|
|
|
|
|
|
|
|
|   |
|
|   |   |   |   |   |   |
|   |   |   |
|   |   |   |   | . |   |   |   |
|
|
|   |
|
|
|   |   |   |   |
|   |   |   |
|   |
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|
|
|   |   |   |
|
|
|
|
|
|
|
|
|
|   |
|
|
|
|
|   |   |   |   |   |   |
|   |
|
|
|
|
|
|
|
|
|
|
|
|   |   |   |   |   |   |
|   |   |   |
|   |   |
|   |   |   |
|   |
|
|
|
|
|
|
|
|
|   |   |
|   |   |
|
|   |
|
|
Template Sequence |   |
L | G | Q | P | A | T | E | L | S | G | G | E | A | Q | R | I | K | L | A | T | E | L | R | R | S | G | R | G | G | T | V | Y | V | L | D | E | P | T | T | G | L | H | P | A | D | V | E | R | L | Q | R | Q | L | V | K | L | V | D | A | G | N | T | V | I | A | V | E | H | K | M | Q | V | V | A | A | S | D | W | V | L |
Template Known Secondary structure |   |
T | T |
|
| G | G | G |
|
| S |  |  |  |  |  |  |  |  |  |  |  |  |  |  | S | S | S | S |
|  |  |  |  |  |  |
| S |
| S | S |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|  |  |  |  |  |
|
|
|  |  |  |  | T | T |
| S |  |  |  |
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|  |  |  |  |  |  |
|
|  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
724 | . | . | . | . | . | 730 | . | . | . | . | . | . | . | . | . | 740 | . | . | . | . | . | . | . | . | . | 750 | . | . | . | . | . | . | . | . | . | 760 | . | . | . | . | . | . | . | . | . | 770 | . | . | . | . | . | . | . | . | . | 780 | . | . | . | . | . | . | . | . | . | 790 | . | . | . | . | . | . | . | . | . | 800 | . | . | . |
  |
  |   |
546 | . | |
|
|
|
|
|
. | . | 550 | . | . | . | . | . | . | . | . | . | 560 | . | . | . | . | |
. | . | . | . | . | 570 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  | . | . | . | . | . | . |  |
|
|  |  |  |  |  |
|
|  |  |  |  |  |  |
| . |
|
|  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
| . |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
V | L | . |
. |
. |
. |
. |
. |
H | R | G | Q | A | V | E | Q | G | T | H | Q | Q | L | L | A | A | . |
Q | G | R | Y | W | Q | M | Y | Q | L | Q | L | A |
Query Conservation |   |
  |
| . | . | . | . | . | . |   |   |
|   |
|   |   |   |
|   |   |   |
|
|   |   |   | . |   |   |   |   |   |   |
|   |   |   |   |   |   |
Alig confidence |   |
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|
|
|   |   |
|   |   |   |
|   |
|
|   |   |
|
|
|   |
|
|   |   |   |   |   |
|   |
|   |   |   |
|   |   |   |
|   |
Template Sequence |   |
D | I | G | P | G | A | G | E | D | G | G | R | L | V | A | Q | G | T | P | A | E | V | A | Q | A | A | G | S | V | T | A | P | Y | L | R | A | A | L | R |
Template Known Secondary structure |   |
 |  |
| S | S | S | G | G | G |
|
| S |  |  |  |  |  | S |  |  |  |  |  | T |
| S | S |
| S | S |  |  |  |  |  |  |  | T |
|
Template Predicted Secondary structure |   |
 |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
804 | . | . | . | . | . | 810 | . | . | . | . | . | . | . | . | . | 820 | . | . | . | . | . | . | . | . | . | 830 | . | . | . | . | . | . | . | . | . | 840 | . | . |
  |