Job Description P23909 Confidence 100.00% Date Thu Jan 5 11:40:34 GMT 2012 Rank 4 Aligned Residues 778 % Identity 29% Template c2o8dB_ PDB info PDB header:dna binding protein/dna Chain: B: PDB Molecule:dna mismatch repair protein msh6; PDBTitle: human mutsalpha (msh2/msh6) bound to adp and a g du mispair Resolution 3.00 Å

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		5	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		E	N	F	D	A	H	T	P	M	M	Q	Q	Y	L	R	L	K	A	Q	H	P	E	I	L	L	F	Y	R	M	G	D	F	Y	E	L	F	Y	D	D	A	K	R	A	S	Q	L	L	D	I	S	L	T	K	R	G	A	S	A	G	E	P	I	P	M	A	G	I	P	Y	H	A	V	E	N	Y	L	A	K	L	V
Query Conservation
Alig confidence																																																									.	.	.	.	.	.
Template Conservation																																																									.	.	.	.	.	.
Template Sequence		D	F	L	N	S	C	T	P	G	M	R	K	W	W	Q	I	K	S	Q	N	F	D	L	V	I	C	Y	K	V	G	K	F	Y	E	L	Y	H	M	D	A	L	I	G	V	S	E	L	G	L	V	F	M	K	G	N	.	.	.	.	.	.	W	A	H	S	G	F	P	E	I	A	F	G	R	Y	S	D	S	L	V
Template Known Secondary structure					T	T	S															T	T	S							T	T																						S	S	S	.	.	.	.	.	.	S							G	G	G
Template Predicted Secondary structure																																																									.	.	.	.	.	.
Template SS confidence
		401	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.							.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.
		85	.	.	.	.	90	.	.	.	.	.	.	.	.	.														100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.				.	.	.	.	.	.	.							.	140	.	.
Predicted Secondary structure																	.	.	.	.	.	.	.	.	.	.	.	.	.																																	.	.	.								.	.	.	.	.	.
Query SS confidence																	.	.	.	.	.	.	.	.	.	.	.	.	.																																	.	.	.								.	.	.	.	.	.
Query Sequence		N	Q	G	E	S	V	A	I	C	E	Q	I	G	D	P	.	.	.	.	.	.	.	.	.	.	.	.	.	A	T	S	K	G	P	V	E	R	K	V	V	R	I	V	T	P	G	T	I	S	D	E	A	L	L	Q	E	R	Q	D	N	.	.	.	L	L	A	A	I	W	Q	.	.	.	.	.	.	D	S	K	G
Query Conservation																	.	.	.	.	.	.	.	.	.	.	.	.	.																																	.	.	.								.	.	.	.	.	.
Alig confidence																	.	.	.	.	.	.	.	.	.	.	.	.	.																																	.	.	.								.	.	.	.	.	.
Template Conservation
Template Sequence		Q	K	G	Y	K	V	A	R	V	E	Q	T	E	T	P	E	M	M	E	A	R	C	R	K	M	A	H	I	S	K	Y	D	R	V	V	R	R	E	I	C	R	I	I	T	K	G	T	Q	T	Y	S	V	L	E	G	D	P	S	E	N	Y	S	K	Y	L	L	S	L	K	E	K	E	E	D	S	S	H	T	R	A
Template Known Secondary structure			T	T										S											T		S	S			S	G	G	G	S											T	T	S					S	S	S				S		S	S													S
Template Predicted Secondary structure
Template SS confidence
		475	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540	.	.	.	.	.	.	.	.	.	550	.	.	.	.
		143	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.				.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.									.	.	200	.	.	.	.	.	.	.	.	.	210	.
Predicted Secondary structure																							.	.	.																																			.	.	.	.	.	.	.	.
Query SS confidence																							.	.	.																																			.	.	.	.	.	.	.	.
Query Sequence		F	G	Y	A	T	L	D	I	S	S	G	R	F	R	L	S	E	P	A	D	R	.	.	.	E	T	M	A	A	E	L	Q	R	T	N	P	A	E	L	L	Y	A	E	D	F	A	E	M	S	L	I	E	G	R	R	G	L	R	.	.	.	.	.	.	.	.	R	R	P	L	W	E	F	E	I	D	T	A	R	Q
Query Conservation																							.	.	.																																			.	.	.	.	.	.	.	.
Alig confidence																							.	.	.																																			.	.	.	.	.	.	.	.
Template Conservation
Template Sequence		Y	G	V	C	F	V	D	T	S	L	G	K	F	F	I	G	Q	F	S	D	D	R	H	C	S	R	F	R	T	L	V	A	H	Y	P	P	V	Q	V	L	F	E	K	G	N	L	S	K	E	T	K	T	I	L	K	S	S	L	S	C	S	L	Q	E	G	L	I	P	G	S	Q	F	W	D	A	S	K	T	L	R
Template Known Secondary structure									T	T	T												S	S											S									T	T	T										T	T	T	T	T	T	S							B	T	T	T	B
Template Predicted Secondary structure
Template SS confidence
		556	.	.	.	560	.	.	.	.	.	.	.	.	.	570	.	.	.	.	.	.	.	.	.	580	.	.	.	.	.	.	.	.	.	590	.	.	.	.	.	.	.	.	.	600	.	.	.	.	.	.	.	.	.	610	.	.	.	.	.	.	.	.	.	620	.	.	.	.	.	.	.	.	.	630	.	.	.	.	.
		212	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.																							.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250											.	.	.	.	.	.	.	.	.
Predicted Secondary structure																		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																								.	.	.	.	.	.	.	.	.	.
Query SS confidence																		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																								.	.	.	.	.	.	.	.	.	.
Query Sequence		Q	L	N	L	Q	F	G	T	R	D	L	V	G	F	G	V	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	E	N	A	P	R	G	L	C	A	A	G	C	L	L	Q	Y	A	K	D	T	Q	R	T	.	.	.	.	.	.	.	.	.	.	T	L	P	H	I	R	S	I	T
Query Conservation																		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																								.	.	.	.	.	.	.	.	.	.
Alig confidence																		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																								.	.	.	.	.	.	.	.	.	.
Template Conservation
Template Sequence		T	L	L	E	E	E	Y	F	R	E	K	L	S	D	G	I	V	M	L	P	Q	V	L	K	G	M	T	S	E	S	D	S	I	G	L	T	P	G	E	K	S	E	L	A	L	S	A	L	G	G	C	V	F	Y	L	K	K	C	L	I	D	Q	E	L	L	S	M	A	N	F	E	E	Y	I	P	L	D	S	D	T
Template Known Secondary structure						T	T	T	T	S	S	S	S														T						T	T						G	G	G																	T	T							T	T									G	G	G	G	T
Template Predicted Secondary structure
Template SS confidence
		636	.	.	.	640	.	.	.	.	.	.	.	.	.	650	.	.	.	.	.	.	.	.	.	660	.	.	.	.	.	.	.	.	.	670	.	.	.	.	.	.	.	.	.	680	.	.	.	.	.	.	.	.	.	690	.	.	.	.	.	.	.	.	.	700	.	.	.	.	.	.	.	.	.	710	.	.	.	.	.
		260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.		.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.				.	.	.
Predicted Secondary structure																									.																																																			.	.	.
Query SS confidence																									.																																																			.	.	.
Query Sequence		M	E	R	E	Q	D	S	I	I	M	D	A	A	T	R	R	N	L	E	I	T	Q	N	.	L	A	G	G	A	E	N	T	L	A	S	V	L	D	C	T	V	T	P	M	G	S	R	M	L	K	R	W	L	H	M	P	V	R	D	T	R	V	L	L	E	R	Q	Q	T	I	G	A	L	Q	.	.	.	D	F	T
Query Conservation																									.																																																			.	.	.
Alig confidence																									.																																																			.	.	.
Template Conservation
Template Sequence		V	S	K	A	Y	Q	R	M	V	L	D	A	V	T	L	N	N	L	E	I	F	L	N	G	T	N	G	S	T	E	G	T	L	L	E	R	V	D	T	C	H	T	P	F	G	K	R	L	L	K	Q	W	L	C	A	P	L	C	N	H	Y	A	I	N	D	R	L	D	A	I	E	D	L	M	V	V	P	D	K	I
Template Known Secondary structure								B		B									T	T		S	S			S	S	S	S													S	S													S		B																		T
Template Predicted Secondary structure
Template SS confidence
		717	.	.	720	.	.	.	.	.	.	.	.	.	730	.	.	.	.	.	.	.	.	.	740	.	.	.	.	.	.	.	.	.	750	.	.	.	.	.	.	.	.	.	760	.	.	.	.	.	.	.	.	.	770	.	.	.	.	.	.	.	.	.	780	.	.	.	.	.	.	.	.	.	790	.	.	.	.	.	.
		336	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.																								.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.
Predicted Secondary structure																						.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query SS confidence																						.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Sequence		A	G	L	Q	P	V	L	R	Q	V	G	D	L	E	R	I	L	A	R	L	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	A	L	R	T	A	R	P	R	D	L	A	R	M	R	H	A	F	Q	Q	L	P	E	L	R	A	Q	L	E	T	V	D	S	A	P	V	Q	A
Query Conservation																						.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Alig confidence																						.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation
Template Sequence		S	E	V	V	E	L	L	K	K	L	P	D	L	E	R	L	L	S	K	I	H	N	V	G	S	P	L	K	S	Q	N	H	P	D	S	R	A	I	M	Y	E	E	T	T	Y	S	K	K	K	I	I	D	F	L	S	A	L	E	G	F	K	V	M	C	K	I	I	G	I	M	E	E	V	A	D	G	F	K	S	K
Template Known Secondary structure									T	T																								G	G	G	S				S																																			T	T
Template Predicted Secondary structure
Template SS confidence
		806	.	.	.	810	.	.	.	.	.	.	.	.	.	820	.	.	.	.	.	.	.	.	.	830	.	.	.	.	.	.	.	.	.	840	.	.	.	.	.	.	.	.	.	850	.	.	.	.	.	.	.	.	.	860	.	.	.	.	.	.	.	.	.	870	.	.	.	.	.	.	.	.	.	880	.	.	.	.	.
		393	.	.	.	.										.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.		.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.
Predicted Secondary structure							.	.	.	.	.	.	.	.	.																															.
Query SS confidence							.	.	.	.	.	.	.	.	.																															.
Query Sequence		L	R	E	K	M	.	.	.	.	.	.	.	.	.	G	E	F	A	E	L	R	D	L	L	E	R	A	I	I	D	T	P	P	V	L	V	R	D	G	G	V	I	A	S	.	G	Y	N	E	E	L	D	E	W	R	A	L	A	D	G	A	T	D	Y	L	E	R	L	E	V	R	E	R	E	R	T	G	L	D	T
Query Conservation							.	.	.	.	.	.	.	.	.																															.
Alig confidence							.	.	.	.	.	.	.	.	.																															.
Template Conservation
Template Sequence		I	L	K	Q	V	I	S	L	Q	T	K	N	P	E	G	R	F	P	D	L	T	V	E	L	N	R	W	D	T	A	F	D	H	E	K	A	R	K	T	G	L	I	T	P	K	A	G	F	S	D	Y	D	Q	A	L	A	D	I	R	E	N	E	Q	S	L	L	E	Y	L	E	K	Q	R	N	R	I	G	C	R	T
Template Known Secondary structure								S	B	T	T	T	S	S	S	S		B												T	T	S								S						T	T																								T	S	S	T	T		S	S		S
Template Predicted Secondary structure
Template SS confidence
		886	.	.	.	890	.	.	.	.	.	.	.	.	.	900	.	.	.	.	.	.	.	.	.	910	.	.	.	.	.	.	.	.	.	920	.	.	.	.	.	.	.	.	.	930	.	.	.	.	.	.	.	.	.	940	.	.	.	.	.	.	.	.	.	950	.	.	.	.	.	.	.	.	.	960	.	.	.	.	.
		463	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		L	K	V	G	F	N	A	V	H	G	Y	Y	I	Q	I	S	R	G	Q	S	H	L	A	P	I	N	Y	M	R	R	Q	T	L	K	N	A	E	R	Y	I	I	P	E	L	K	E	Y	E	D	K	V	L	T	S	K	G	K	A	L	A	L	E	K	Q	L	Y	E	E	L	F	D	L	L	L	P	H	L	E	A	L
Query Conservation
Alig confidence
Template Conservation
Template Sequence		I	V	Y	W	G	I	G	R	N	R	Y	Q	L	E	I	P	E	N	F	T	T	R	N	L	P	E	Y	E	L	K	S	T	K	K	G	C	K	R	Y	W	T	K	T	I	E	K	K	L	A	N	L	I	N	A	E	E	R	R	D	V	S	L	K	D	C	M	R	R	L	F	Y	N	F	D	K	N	Y	K	D	W
Template Known Secondary structure								G	G	G								T	T	S		S	S											S	S							T	T	T																																T	T
Template Predicted Secondary structure
Template SS confidence
		967	.	.	970	.	.	.	.	.	.	.	.	.	980	.	.	.	.	.	.	.	.	.	990	.	.	.	.	.	.	.	.	.	1000	.	.	.	.	.	.	.	.	.	1010	.	.	.	.	.	.	.	.	.	1020	.	.	.	.	.	.	.	.	.	1030	.	.	.	.	.	.	.	.	.	1040	.	.	.	.	.	.
		543	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.	.	560	.	.	.	.	.	.			.	.	.	570	.	.	.					.	.	.	.	.	.	580	.	.	.	.	.	.	.	.	.	590	.	.	.	.	.	.	.	.	.	600	.	.	.	.								.	.	.	.	.
Predicted Secondary structure																										.	.								.	.	.	.																																.	.	.	.	.	.	.
Query SS confidence																										.	.								.	.	.	.																																.	.	.	.	.	.	.
Query Sequence		Q	Q	S	A	S	A	L	A	E	L	D	V	L	V	N	L	A	E	R	A	Y	T	L	N	.	.	Y	T	C	P	T	F	I	.	.	.	.	D	K	P	G	I	R	I	T	E	G	R	H	P	V	V	E	Q	V	L	N	E	P	F	I	A	N	P	L	N	L	S	.	.	.	.	.	.	.	P	Q	R	R	M
Query Conservation																										.	.								.	.	.	.																																.	.	.	.	.	.	.
Alig confidence																										.	.								.	.	.	.																.	.	.	.	.												.	.	.	.	.	.	.
Template Conservation																																																						.	.	.	.	.
Template Sequence		Q	S	A	V	E	C	I	A	V	L	D	V	L	L	C	L	A	N	Y	S	R	G	G	D	G	P	M	C	R	P	V	I	L	L	P	E	D	T	P	P	F	L	E	L	K	G	S	R	H	P	C	G	.	.	.	.	.	D	D	F	I	P	N	D	I	L	I	G	C	E	E	E	E	Q	E	N	K	A	Y	C
Template Known Secondary structure																					T	T		S	S	S			B							T	T	T	S		S													.	.	.	.	.															S	T	T
Template Predicted Secondary structure																																																						.	.	.	.	.
Template SS confidence
		1048	.	1050	.	.	.	.	.	.	.	.	.	1060	.	.	.	.	.	.	.	.	.	1070	.	.	.	.	.	.	.	.	.	1080	.	.	.	.	.	.	.	.	.	1090	.	.	.	.	.	.	.	.	.						1100	.	.	.	.	.	.	.	.	.	1110	.	.	.	.	.	.	.	.	.	1120	.	.
		610	.	.	.	.	.	.	.	.	.	620	.	.	.	.	.	.	.	.	.	630	.	.	.	.	.	.	.	.	.	640	.	.	.	.	.	.	.	.	.	650	.	.	.	.	.	.	.	.	.	660	.	.	.	.	.	.	.	.	.	670	.	.	.	.	.	.	.	.	.	680	.	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		L	I	I	T	G	P	N	M	G	G	K	S	T	Y	M	R	Q	T	A	L	I	A	L	M	A	Y	I	G	S	Y	V	P	A	Q	K	V	E	I	G	P	I	D	R	I	F	T	R	V	G	A	A	D	D	L	A	S	G	R	S	T	F	M	V	E	M	T	E	T	A	N	I	L	H	N	A	T	E	Y	S	L
Query Conservation
Alig confidence																																																			.	.	.	.	.	.	.	.	.
Template Conservation																																																			.	.	.	.	.	.	.	.	.
Template Sequence		V	L	V	T	G	P	N	M	G	G	K	S	T	L	M	R	Q	A	G	L	L	A	V	M	A	Q	M	G	C	Y	V	P	A	E	V	C	R	L	T	P	I	D	R	V	F	T	R	L	G	.	.	.	.	.	.	.	.	.	S	T	F	F	V	E	L	S	E	T	A	S	I	L	M	H	A	T	A	H	S	L
Template Known Secondary structure					B			T	T	S	S																T	T	T			B	S	S	S								S	B							.	.	.	.	.	.	.	.	.																			T	T
Template Predicted Secondary structure																																																			.	.	.	.	.	.	.	.	.
Template SS confidence
		1130	.	.	.	.	.	.	.	.	.	1140	.	.	.	.	.	.	.	.	.	1150	.	.	.	.	.	.	.	.	.	1160	.	.	.	.	.	.	.	.	.	1170	.	.	.	.	.	.	.	.										.	1180	.	.	.	.	.	.	.	.	.	1190	.	.	.	.	.	.	.	.	.	1200
		690	.	.	.	.	.	.	.	.	.	700	.	.	.	.	.	.	.	.	.	710	.	.	.	.	.	.	.	.	.	720	.	.	.	.	.	.	.	.	.	730	.	.	.	.	.	.	.	.	.	740	.	.	.	.	.	.	.	.	.	750	.	.	.	.	.	.	.	.	.	760	.	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		V	L	M	D	E	I	G	R	G	T	S	T	Y	D	G	L	S	L	A	W	A	C	A	E	N	L	A	N	K	I	K	A	L	T	L	F	A	T	H	Y	F	E	L	T	Q	L	P	E	K	M	E	G	V	A	N	V	H	L	D	A	L	E	H	G	D	T	I	A	F	M	H	S	V	Q	D	G	A	A	S	K
Query Conservation
Alig confidence																																																														.	.	.	.	.	.
Template Conservation																																																														.	.	.	.	.	.
Template Sequence		V	L	V	D	E	L	G	R	G	T	A	T	F	D	G	T	A	I	A	N	A	V	V	K	E	L	A	E	T	I	K	C	R	T	L	F	S	T	H	Y	H	S	L	V	E	D	Y	S	Q	N	V	A	V	R	L	G	H	M	A	C	.	.	.	.	.	.	M	T	F	L	Y	K	F	I	K	G	A	C	P	K
Template Known Secondary structure							S		T	T	S																			T	S																	T	S	S		S	S									.	.	.	.	.	.									S	S
Template Predicted Secondary structure																																																														.	.	.	.	.	.
Template SS confidence
		1210	.	.	.	.	.	.	.	.	.	1220	.	.	.	.	.	.	.	.	.	1230	.	.	.	.	.	.	.	.	.	1240	.	.	.	.	.	.	.	.	.	1250	.	.	.	.	.	.	.	.	.	1260	.	.	.	.	.	.	.	.	.							1270	.	.	.	.	.	.	.	.	.	1280	.	.	.
		770	.	.	.	.	.	.	.	.	.	780	.	.	.	.	.	.	.	.	.	790	.	.	.	.	.	.	.	.	.	800	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		S	Y	G	L	A	V	A	A	L	A	G	V	P	K	E	V	I	K	R	A	R	Q	K	L	R	E	L	E	S	I	S	P	N	A	A	A	T	Q	V
Query Conservation
Alig confidence
Template Conservation
Template Sequence		S	Y	G	F	N	A	A	R	L	A	N	L	P	E	E	V	I	Q	K	G	H	R	K	A	R	E	F	E	K	M	N	Q	S	L	R	L	F	R	E
Template Known Secondary structure											T	T																T	T	S	S	T	T		S	S	S	S
Template Predicted Secondary structure
Template SS confidence
		1297	.	.	1300	.	.	.	.	.	.	.	.	.	1310	.	.	.	.	.	.	.	.	.	1320	.	.	.	.	.	.	.	.	.	1330	.	.	.	.	.