Job Description P23909 Confidence 100.00% Date Thu Jan 5 11:40:34 GMT 2012 Rank 3 Aligned Residues 778 % Identity 27% Template c2o8bA_ PDB info PDB header:dna binding protein/dna Chain: A: PDB Molecule:dna mismatch repair protein msh2; PDBTitle: human mutsalpha (msh2/msh6) bound to adp and a g t mispair Resolution 2.75 Å

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		6	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.				.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.
Predicted Secondary structure																																																					.	.	.
Query SS confidence																																																					.	.	.
Query Sequence		N	F	D	A	H	T	P	M	M	Q	Q	Y	L	R	L	K	A	Q	H	P	E	I	L	L	F	Y	R	M	G	D	F	Y	E	L	F	Y	D	D	A	K	R	A	S	Q	L	L	D	I	S	L	T	.	.	.	K	R	G	A	S	A	G	E	P	I	P	M	A	G	I	P	Y	H	A	V	E	N	Y	L	A	K
Query Conservation																																																					.	.	.
Alig confidence																																																					.	.	.
Template Conservation
Template Sequence		E	S	A	A	E	V	G	F	V	R	F	F	Q	G	M	P	E	K	P	T	T	T	V	R	L	F	D	R	G	D	F	Y	T	A	H	G	E	D	A	L	L	A	A	R	E	V	F	K	T	Q	G	V	I	K	Y	M	G	P	A	G	A	K	N	L	Q	S	V	V	L	S	K	M	N	F	E	S	F	V	K	D
Template Known Secondary structure															T	S					T	T								S	S	S															T	S	S		S	T	T					S		T	T
Template Predicted Secondary structure
Template SS confidence
		12	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.
			83	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.					140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.
Predicted Secondary structure		.																																																										.	.	.	.
Query SS confidence		.																																																										.	.	.	.
Query Sequence		.	L	V	N	Q	G	E	S	V	A	I	C	E	Q	I	G	D	P	A	T	S	K	G	P	V	E	R	K	V	V	R	I	V	T	P	G	T	I	S	D	E	A	L	L	Q	E	R	Q	D	N	L	L	A	A	I	W	Q	D	.	.	.	.	S	K	G	F	G	Y	A	T	L	D	I	S	S	G	R	F	R	L
Query Conservation		.																																																										.	.	.	.
Alig confidence		.																		.	.	.	.																																					.	.	.	.
Template Conservation																				.	.	.	.
Template Sequence		L	L	L	V	R	Q	Y	R	V	E	V	Y	K	N	R	A	G	S	.	.	.	.	K	E	N	D	W	Y	L	A	Y	K	A	S	P	G	N	L	S	Q	F	E	D	I	L	F	G	N	N	I	G	V	V	G	V	K	M	S	A	V	D	G	Q	R	Q	V	G	V	G	Y	V	D	S	I	Q	R	K	L	G	L
Template Known Secondary structure					T	S														.	.	.	.												B	T	T	B		G	G	G	T	T	T	S	T	T												S	S	S	S	S										T	T	T	T
Template Predicted Secondary structure																				.	.	.	.
Template SS confidence
		92	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.					110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.
		158	.	160	.	.	.				.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.								.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.
Predicted Secondary structure								.	.	.																																.	.	.	.	.	.	.																																	.
Query SS confidence								.	.	.																																.	.	.	.	.	.	.																																	.
Query Sequence		S	E	P	A	D	R	.	.	.	E	T	M	A	A	E	L	Q	R	T	N	P	A	E	L	L	Y	A	E	D	F	A	E	M	S	L	I	E	G	R	R	.	.	.	.	.	.	.	G	L	R	R	R	P	L	W	E	F	E	I	D	T	A	R	Q	Q	L	N	L	Q	F	G	T	R	D	L	V	G	F	G	.
Query Conservation								.	.	.																																.	.	.	.	.	.	.																																	.
Alig confidence								.	.	.																																.	.	.	.	.	.	.																																	.
Template Conservation
Template Sequence		C	E	F	P	D	N	D	Q	F	S	N	L	E	A	L	L	I	Q	I	G	P	K	E	C	V	L	P	G	G	E	T	A	G	D	M	G	K	L	R	Q	I	I	Q	R	G	G	I	L	I	T	E	R	K	K	A	D	F	S	T	K	D	I	Y	Q	D	L	N	R	G	K	K	G	E	Q	M	N	S	A	V	L
Template Known Secondary structure								S	S														S									S	S	S											T	T	T							S	S	T	T					S					T						S		T	T	T	T	T	S
Template Predicted Secondary structure
Template SS confidence
		176	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.
			227	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.
Predicted Secondary structure		.
Query SS confidence		.
Query Sequence		.	V	E	N	A	P	R	G	L	C	A	A	G	C	L	L	Q	Y	A	K	D	T	Q	R	T	T	L	P	H	I	R	S	I	T	M	E	R	E	Q	D	S	I	I	M	D	A	A	T	R	R	N	L	E	I	T	Q	N	L	A	G	G	A	E	N	T	L	A	S	V	L	D	C	T	V	T	P	M	G	S	R
Query Conservation		.
Alig confidence		.																																																												.	.
Template Conservation																																																														.	.
Template Sequence		P	E	M	E	N	Q	V	A	V	S	S	L	S	A	V	I	K	F	L	E	L	L	S	D	D	S	N	F	G	Q	F	E	L	T	T	F	D	F	S	Q	Y	M	K	L	D	I	A	A	V	R	A	L	N	L	F	Q	G	S	T	G	.	.	S	Q	S	L	A	A	L	L	N	K	C	K	T	P	Q	G	Q	R
Template Known Secondary structure		G	G	G	G															S		T	T	S	S	T	T	S		S									T	T	S	B											T	T		S						.	.												S	S
Template Predicted Secondary structure																																																														.	.
Template SS confidence
		259	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.			.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.
		306	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.					.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.
Predicted Secondary structure																																						.	.	.	.
Query SS confidence																																						.	.	.	.
Query Sequence		M	L	K	R	W	L	H	M	P	V	R	D	T	R	V	L	L	E	R	Q	Q	T	I	G	A	L	Q	D	F	T	A	G	L	Q	P	V	.	.	.	.	L	R	Q	V	G	D	L	E	R	I	L	A	R	L	A	L	R	T	A	R	P	R	D	L	A	R	M	R	H	A	F	Q	Q	L	P	E	L	R	A	Q
Query Conservation																																						.	.	.	.
Alig confidence																																						.	.	.	.
Template Conservation
Template Sequence		L	V	N	Q	W	I	K	Q	P	L	M	D	K	N	R	I	E	E	R	L	N	L	V	E	A	F	V	E	D	A	E	L	R	Q	T	L	Q	E	D	L	L	R	R	F	P	D	L	N	R	L	A	K	K	F	Q	R	Q	A	A	N	L	Q	D	C	Y	R	L	Y	Q	G	I	N	Q	L	P	N	V	I	Q	A
Template Known Secondary structure									S		B																				S								T	T	T	G	G	G													T	T																T	S
Template Predicted Secondary structure
Template SS confidence
		341	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420
		382	.	.	.	.	.	.									.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.
Predicted Secondary structure									.	.	.	.	.	.	.	.
Query SS confidence									.	.	.	.	.	.	.	.
Query Sequence		L	E	T	V	D	S	A	.	.	.	.	.	.	.	.	P	V	Q	A	L	R	E	K	M	G	E	F	A	E	L	R	D	L	L	E	R	A	I	I	D	T	P	P	V	L	V	R	D	G	G	V	I	A	S	G	Y	N	E	E	L	D	E	W	R	A	L	A	D	G	A	T	D	Y	L	E	R	L	E	V	R
Query Conservation									.	.	.	.	.	.	.	.
Alig confidence									.	.	.	.	.	.	.	.																								.	.
Template Conservation																																								.	.
Template Sequence		L	E	K	H	E	G	K	H	Q	K	L	L	L	A	V	F	V	T	P	L	T	D	L	R	S	D	F	S	K	F	Q	E	M	I	E	T	T	L	.	.	D	M	D	Q	V	E	N	H	E	F	L	V	K	P	S	F	D	P	N	L	S	E	L	R	E	I	M	N	D	L	E	K	K	M	Q	S	T	L	I	S
Template Known Secondary structure			T	T	S	S	S	S	T	T		S	S	T	T	S	S											T											B	.	.						S	S	S				B		T	T	T
Template Predicted Secondary structure																																								.	.
Template SS confidence
		421	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.			.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.
		454	.	.	.	.	.	460				.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.			.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.
Predicted Secondary structure									.	.	.																										.	.
Query SS confidence									.	.	.																										.	.
Query Sequence		E	R	E	R	T	G	L	.	.	.	D	T	L	K	V	G	F	N	A	V	H	G	Y	Y	I	Q	I	S	R	G	Q	S	H	L	A	.	.	P	I	N	Y	M	R	R	Q	T	L	K	N	A	E	R	Y	I	I	P	E	L	K	E	Y	E	D	K	V	L	T	S	K	G	K	A	L	A	L	E	K	Q	L	Y
Query Conservation									.	.	.																										.	.
Alig confidence									.	.	.																										.	.
Template Conservation
Template Sequence		A	A	R	D	L	G	L	D	P	G	K	Q	I	K	L	D	S	S	A	Q	F	G	Y	Y	F	R	V	T	C	K	E	E	K	V	L	R	N	N	K	N	F	S	T	V	D	I	Q	K	N	G	V	K	F	T	N	S	K	L	T	S	L	N	E	E	Y	T	K	N	K	T	E	Y	E	E	A	Q	D	A	I	V
Template Known Secondary structure							T			B	T	T	T	B	B					T	T	T								S				T	T	T	T	S		S	S								T	T
Template Predicted Secondary structure
Template SS confidence
		499	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540	.	.	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.	.	560	.	.	.	.	.	.	.	.	.	570	.	.	.	.	.	.	.	.
		529	530	.	.	.	.	.	.	.	.	.	540	.	.	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.	.	560	.	.	.	.			.	.	.	.	.	570	.	.	.	.	.	.	.			.	.	580	.	.	.	.	.	.	.	.	.	590	.	.	.	.	.	.	.	.	.	600	.	.	.	.
Predicted Secondary structure																																						.	.														.	.
Query SS confidence																																						.	.														.	.
Query Sequence		E	E	L	F	D	L	L	L	P	H	L	E	A	L	Q	Q	S	A	S	A	L	A	E	L	D	V	L	V	N	L	A	E	R	A	Y	T	.	.	L	N	Y	T	C	P	T	F	I	D	K	P	G	.	.	I	R	I	T	E	G	R	H	P	V	V	E	Q	V	L	N	E	P	F	I	A	N	P	L	N	L	S
Query Conservation																																						.	.														.	.
Alig confidence																																						.	.														.	.
Template Conservation
Template Sequence		K	E	I	V	N	I	S	S	G	Y	V	E	P	M	Q	T	L	N	D	V	L	A	Q	L	D	A	V	V	S	F	A	H	V	S	N	G	A	P	V	P	Y	V	R	P	A	I	L	E	K	G	Q	G	R	I	I	L	K	A	S	R	H	A	C	V	E	V	Q	D	E	I	A	F	I	P	N	D	V	Y	F	E
Template Known Secondary structure									G	G	G																											S	S	S			B							T	T		S										T	T	T	T	T	S	T	T
Template Predicted Secondary structure
Template SS confidence
		579	580	.	.	.	.	.	.	.	.	.	590	.	.	.	.	.	.	.	.	.	600	.	.	.	.	.	.	.	.	.	610	.	.	.	.	.	.	.	.	.	620	.	.	.	.	.	.	.	.	.	630	.	.	.	.	.	.	.	.	.	640	.	.	.	.	.	.	.	.	.	650	.	.	.	.	.	.	.	.
		605	.	.	.		.	610	.	.	.	.	.	.	.	.	.	620	.	.	.	.	.	.	.	.	.	630	.	.	.	.	.	.	.	.	.	640	.	.	.	.	.	.	.	.	.	650	.	.	.	.	.	.	.	.	.	660	.	.	.	.	.	.	.	.	.	670	.	.	.	.	.	.	.	.	.	680	.	.	.
Predicted Secondary structure						.
Query SS confidence						.
Query Sequence		P	Q	R	R	.	M	L	I	I	T	G	P	N	M	G	G	K	S	T	Y	M	R	Q	T	A	L	I	A	L	M	A	Y	I	G	S	Y	V	P	A	Q	K	V	E	I	G	P	I	D	R	I	F	T	R	V	G	A	A	D	D	L	A	S	G	R	S	T	F	M	V	E	M	T	E	T	A	N	I	L	H	N
Query Conservation						.
Alig confidence						.																																																			.	.	.	.	.	.	.	.	.
Template Conservation																																																									.	.	.	.	.	.	.	.	.
Template Sequence		K	D	K	Q	M	F	H	I	I	T	G	P	N	M	G	G	K	S	T	Y	I	R	Q	T	G	V	I	V	L	M	A	Q	I	G	C	F	V	P	C	E	S	A	E	V	S	I	V	D	C	I	L	A	R	V	G	.	.	.	.	.	.	.	.	.	S	T	F	M	A	E	M	L	E	T	A	S	I	L	R	S
Template Known Secondary structure		T	T	S	S								S	T	T	S	S																	T	T			B	S	S	S								S								.	.	.	.	.	.	.	.	.															T	T
Template Predicted Secondary structure																																																									.	.	.	.	.	.	.	.	.
Template SS confidence
		659	660	.	.	.	.	.	.	.	.	.	670	.	.	.	.	.	.	.	.	.	680	.	.	.	.	.	.	.	.	.	690	.	.	.	.	.	.	.	.	.	700	.	.	.	.	.	.	.	.	.	710	.	.	.										.	.	.	.	.	.	720	.	.	.	.	.	.	.	.	.
		684	.	.	.	.	.	690	.	.	.	.	.	.	.	.	.	700	.	.	.	.	.	.	.	.	.	710	.	.	.	.	.	.	.	.	.	720	.	.	.	.	.	.	.	.	.	730	.	.	.	.	.	.	.	.	.	740	.	.	.	.	.	.	.	.	.	750	.	.	.	.	.	.	.	.	.	760	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		A	T	E	Y	S	L	V	L	M	D	E	I	G	R	G	T	S	T	Y	D	G	L	S	L	A	W	A	C	A	E	N	L	A	N	K	I	K	A	L	T	L	F	A	T	H	Y	F	E	L	T	Q	L	P	E	K	M	E	G	V	A	N	V	H	L	D	A	L	E	H	G	D	T	I	A	F	M	H	S	V	Q
Query Conservation
Alig confidence
Template Conservation
Template Sequence		A	T	K	D	S	L	I	I	I	D	E	L	G	R	G	T	S	T	Y	D	G	F	G	L	A	W	A	I	S	E	Y	I	A	T	K	I	G	A	F	C	M	F	A	T	H	F	H	E	L	T	A	L	A	N	Q	I	P	T	V	N	N	L	H	V	T	A	L	T	T	E	E	T	L	T	M	L	Y	Q	V	K
Template Known Secondary structure				T	T	S						S				S	S																			T	T											T	T	S	T	T					S	S	S												S	S
Template Predicted Secondary structure
Template SS confidence
		739	740	.	.	.	.	.	.	.	.	.	750	.	.	.	.	.	.	.	.	.	760	.	.	.	.	.	.	.	.	.	770	.	.	.	.	.	.	.	.	.	780	.	.	.	.	.	.	.	.	.	790	.	.	.	.	.	.	.	.	.	800	.	.	.	.	.	.	.	.	.	810	.	.	.	.	.	.	.	.
		764	.	.	.	.	.	770	.	.	.	.	.	.	.	.	.	780	.	.	.	.	.	.	.	.	.	790	.	.	.	.	.	.	.	.	.	800
Predicted Secondary structure
Query SS confidence
Query Sequence		D	G	A	A	S	K	S	Y	G	L	A	V	A	A	L	A	G	V	P	K	E	V	I	K	R	A	R	Q	K	L	R	E	L	E	S	I	S
Query Conservation
Alig confidence
Template Conservation
Template Sequence		K	G	V	C	D	Q	S	F	G	I	H	V	A	E	L	A	N	F	P	K	H	V	I	E	C	A	K	Q	K	A	L	E	L	E	E	F	Q
Template Known Secondary structure			S			S											T	T																		T		.
Template Predicted Secondary structure
Template SS confidence
		819	820	.	.	.	.	.	.	.	.	.	830	.	.	.	.	.	.	.	.	.	840	.	.	.	.	.	.	.	.	.	850	.	.	.	.	.