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Job DescriptionP23909
Confidence100.00%DateThu Jan 5 11:40:34 GMT 2012
Rank5Aligned Residues746
% Identity42%Templatec1ewqA_
PDB info PDB header:replication/dnaChain: A: PDB Molecule:dna mismatch repair protein muts; PDBTitle: crystal structure taq muts complexed with a heteroduplex2 dna at 2.2 a resolution
Resolution2.20 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   5....10.........20.........30.........40.........50.........60.........70.........80....
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Query Sequence  ENFDAHTPMMQQYLRLKAQHPEILLFYRMGDFYELFYDDAKRASQLLDISLTKRGASAGEPIPMAGIPYHAVENYLAKLV
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Template Sequence  EGPGPLPPLLQQYVELRDQYPDYLLLFQVGDFYECFGEDAERLARALGLVLTHKTSK. DFTTPXAGIPLRAFEAYAERLL
Template Known Secondary structure  S

S



TTSTTT



S.S
GGG
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   8.10.........20.........30.........40.........50.........60.... .....70.........80......
 
   85....90.........100.........110.........120.........130.........140.........150.........160....
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Query Sequence  NQGESVAICEQIGDPATSKGPVERKVVRIVTPGTISDEALLQERQDNLLAAIWQDSKGFGYATLDISSGRFRLSEPADRE
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Template Sequence  KXGFRLAVADQVEPAEEAEGLVRREVTQLLTPGTLLQESLL. PREANYLAAIAT. GDGWGLAFLDVSTGEFKGTVLKSKS
Template Known Secondary structure  TT


S
GGG
SSS


GGG


GGGS.
SS


.SSSTTTTSS
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   87..90.........100.........110.........120....... ..130......... 140.........150.........160....
 
   165....170.........180.........190.........200.........210.........220...... ...230.........240.
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Query Sequence  TMAAELQRTNPAELLYAEDFAEMSLIEGRRGLRRRPLWEFEIDTARQQLNLQFGTRDLVGFG. . . VENAPRGLCAAGCLL
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Template Sequence  ALYDELFRHRPAEVLLAPELLEN. . . . . . . . . . . . . . . . . . . GAFLDEFRKRFPVXLSEAPFEPEGEGPLALRRARGALL
Template Known Secondary structure 

S

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S






SSS
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   165....170.........180....... ..190.........200.........210.........220.....
 
   242.......250.........260.........270.........280.........290.........300.........310.........320.
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Query Sequence  QYAKDTQRTTLPHIRSITMEREQDSIIMDAATRRNLEITQNLAGGAENTLASVLDCTVTPMGSRMLKRWLHMPVRDTRVL
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Template Sequence  AYAQRTQGGAL. SLQPFRFYDPGAFXRLPEATLRALEVFEPLRG. . QDTLFSVLDETRTAPGRRLLQSWLRHPLLDRGPL
Template Known Secondary structure  TS

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GGGS
B

TTSSS
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   226...230...... ...240.........250.........260........ .270.........280.........290.........300..
 
   322.......330.... .....340.........350.........360.........370.........380.........390........
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Query Sequence  LERQQTIGALQDF. . . TAGLQPVLRQVGDLERILARLALRTARPRDLARMRHAFQQLPELRAQLETVDSAPVQALREKMG
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Template Sequence  EARLDRVEGFVREGALREGVRRLLYRLADLERLATRLELGRASPKDLGALRRSLQILPELRALLGEEVG. . . . . . . . . LP
Template Known Secondary structure 
TT


TT



TTS
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   303......310.........320.........330.........340.........350.........360.........370. ..
 
   399400.........410.........420.........430.........440.........450.........460.........470........
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Query Sequence  EFAELRDLLERAIIDTPPVLVRDGGVIASGYNEELDEWRALADGATDYLERLEVRERERTGLDTLKVGFNAVHGYYIQIS
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Template Sequence  DLSPLKEELEAALVEDPPLKVSEGGLIREGYDPDLDALRAAHREGVAYFLELEERERERTGIPTLKVGYNAVFGYYLEVT
Template Known Secondary structure 

B
SS

S
TTSS

B
TTS


TT
TTT
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   374.....380.........390.........400.........410.........420.........430.........440.........450...
 
   479480.........490.........500.........510.........520.........530.........540.........550........
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Query Sequence  RGQSHLAPINYMRRQTLKNAERYIIPELKEYEDKVLTSKGKALALEKQLYEELFDLLLPHLEALQQSASALAELDVLVNL
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Template Sequence  RPYYERVPKEYRPVQTLKDRQRYTLPEXKEKEREVYRLEALIRRREEEVFLEVRERAKRQAEALREAARILAELDVYAAL
Template Known Secondary structure  GGGGGGS
TT

SS
TT
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   454.....460.........470.........480.........490.........500.........510.........520.........530...
 
   559560.........570.........580.........590.........600.........610.........620.........630........
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Query Sequence  AERAYTLNYTCPTFIDKPGIRITEGRHPVVEQVLNEPFIANPLNLSPQRRMLIITGPNMGGKSTYMRQTALIALMAYIGS
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Template Sequence  AEVAVRYGYVRPRFGDR. . LQIRAGRHPVVER. . RTEFVPNDLEX. . AHELVLITGPNXAGKSTFLRQTALIALLAQVGS
Template Known Secondary structure  T
B

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TTGGG..TS



..SS
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   534.....540.........550 .........560... ......570.... .....580.........590.........600.......
 
   639640.........650.........660.........670.........680.........690.........700.........710........
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Query Sequence  YVPAQKVEIGPIDRIFTRVGAADDLASGRSTFMVEMTETANILHNATEYSLVLMDEIGRGTSTYDGLSLAWACAENLANK
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Template Sequence  FVPAEEAHLPLFDGIYTRIGA. . . . . . GKSTFXVEXEEVALILKEATENSLVLLDEVGRGTSSLDGVAIATAVAEALHER
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BSSS


S


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   608.610.........620........ .630.........640.........650.........660.........670.........680.
 
   719720.........730.........740.........750.........760.........770.........780.........790........
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Query Sequence  IKALTLFATHYFELTQLPEKMEGVANVHLDALEHGDTIAFMHSVQDGAASKSYGLAVAALAGVPKEVIKRARQKLRELES
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Template Sequence  . RAYTLFATHYFELTALG. . LPRLKNLHVAAREEAGGLVFYHQVLPGPASKSYGVEVAAXAGLPKEVVARARALLQAXAA
Template Known Secondary structure  .T



T

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TT

TT
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   688.690.........700.... .....710.........720.........730.........740.........750.........760....
 
   799
Predicted Secondary structure 
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Query Sequence  I
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Template Conservation 
Template Sequence  R
Template Known Secondary structure 
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   765
 
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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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