|   |
53 | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | |
100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . |
Predicted Secondary structure |   |
|
|  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
P | R | L | L | V | V | C | G | P | C | S | I | H | D | P | E | T | A | L | E | Y | A | R | R | F | K | A | L | A | A | E | V | S | D | S | L | Y | L | V | M | R | V | Y | F | E | K | P | . |
R | T | T | V | G | W | K | G | L | I | N | D | P | H | M | D | G | S | F | D | V | E | A | G | L | Q | I | A | R | K | L | L |
Query Conservation |   |
  |
|
|
|
|
|   |
|
|
|
|
|   |
|   |   |   |   |
|
|
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|   |   |   |   |
|
| . |
|
|
|   |
|
|
|
|
|
|   |
|
|   |   |   |   |   |   |   |
|
|   |
|
|   |   |   |
|   |
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
| . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
Template Conservation |   |
|   |   |   |
|
|
|
|
|
|
|
|
|
|   |   |   |   |
|   |   |
|   |   |
|
|   |   |   |   |   |   | . |   |   |   |   |   |
|   |
|   |   |   |   |
|
|   |
|
|
| . | . | . | . | . | . | . | . | . |   |   |   |   |   |
|   |
|   |
|   |
|
|   |   |
|   |   |   | . |
Template Sequence |   |
E | K | F | L | V | I | A | G | P | C | A | I | E | S | E | E | L | L | L | K | V | G | E | E | I | K | R | L | S | E | K | F | . |
K | E | V | E | F | V | F | K | S | S | F | D | K | A | N | R | S | S | . |
. |
. |
. |
. |
. |
. |
. |
. |
I | H | S | F | R | G | H | G | L | E | Y | G | V | K | A | L | R | K | V | . |
Template Known Secondary structure |   |
|
|  |  |  |  |  |  |
| S | B |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| . | T | T |  |  |  |  |  |  |
| B | S |
|
| T | T |
| S | S | . | . | . | . | . | . | . | . | . | T | T | S |
|
|
| S |
|  |  |  |  |  |  |  |  |  |  |  | . |
Template Predicted Secondary structure |   |
|
|  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . |
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  | . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
1002 | . | . | . | . | . | . | . | 1010 | . | . | . | . | . | . | . | . | . | 1020 | . | . | . | . | . | . | . | . | . | 1030 | . | . | . | |
. | . | . | . | . | . | 1040 | . | . | . | . | . | . | . | . | . | 1050 | . | |
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | . | 1060 | . | . | . | . | . | . | . | . | . | 1070 | |
  |
  |   |
132 | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . |
Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
L | E | L | V | N | M | G | L | P | L | A | T | E | A | L | D | P | N | S | P | Q | Y | L | G | D | L | F | S | W | S | A | I | G | A | R | T | T | E | S | Q | T | H | R | E | M | A | S | G | L | S | M | P | V | G | F | K | N | G | T | D | G | S | L | A | T | A | I | N | A | M | R | A | A | A | Q | P | H | R | F | V |
Query Conservation |   |
  |   |   |   |
|   |
|
|
|
|
|
|
|   |
|
|   |   |   |   |   |
|   |   |
|
|
|   |   |   |   |
|
|
|
|
|   |
|
|
|   |
|
|
|   |
|
|
|
|   |   |
|
|
|
|
|
|   |
|   |
|   |
|   |   |
|
|   |
|
|   |
|
|   |   |   |
|   |
|
|
Alig confidence |   |
. | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . |
Template Conservation |   |
. | . |   |   |   |   |
|
|   |   |   |
|
|
|   |
|   |   |   |   |   |   |
|   |   |   |
|
|   |   |
|
|
|
|   |   |   |   |
|   |   |
|
|   |   |   |
|   |   |
|
|
|
|   |
|
|   |
|   |   |   |   |   |   |
|   |   |   |
| . | . | . | . | . | . | . | . | . | . | . |
Template Sequence |   |
. |
. |
K | E | E | F | G | L | K | I | T | T | D | I | H | E | S | W | Q | A | E | P | V | A | E | V | A | D | I | I | Q | I | P | A | F | L | C | R | Q | T | D | L | L | L | A | A | A | K | T | G | R | A | V | N | V | K | K | G | Q | F | L | A | P | W | D | T | K | N | V | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Template Known Secondary structure |   |
. | . |  |  |  |  |
|
|  |  |  |  |  |
| S | S | G | G | G |  |  |  |  |  | T | T |
| S |  |  |  |  |
| G | G | G | T | T |
|  |  |  |  |  |  |  |  | T | T | T | S |  |  |  |  |  |
|
| T | T |
|
| G | G | G | G |  |  |  | . | . | . | . | . | . | . | . | . | . | . |
Template Predicted Secondary structure |   |
. | . |  |  |  |  |
|
|
|  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
|
1071 | . | . | . | . | . | . | . | . | 1080 | . | . | . | . | . | . | . | . | . | 1090 | . | . | . | . | . | . | . | . | . | 1100 | . | . | . | . | . | . | . | . | . | 1110 | . | . | . | . | . | . | . | . | . | 1120 | . | . | . | . | . | . | . | . | . | 1130 | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
  |
  |   |
212 | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | |
|
|
|
|
|
270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
G | I | N | Q | A | G | Q | V | A | L | L | Q | T | Q | G | N | P | D | G | H | V | I | L | R | G | G | K | A | P | N | Y | S | P | A | D | V | A | Q | C | E | K | E | M | E | Q | A | G | L | R | P | S | L | M | V | D | C | S | H | . |
. |
. |
. |
. |
. |
G | N | S | N | K | D | Y | R | R | Q | P | A | V | A | E | S |
Query Conservation |   |
  |
|   |   |   |
|   |   |   |   |
|   |
|   |
|
|   |   |   |
|
|
|
|
|
|
|   |   |
|
|
|   |   |   |   |
|   |   |   |   |   |   |
|   |
|   |   |   |   |   |   |
|
|
|
|   |
|
| . | . | . | . | . | . |
|
|
|   |
|   |   |   |   |
|
|   |
|   |   |   |
Alig confidence |   |
. | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
. | . | . | . | . | . | . |
|
|   |
|   |   |   |
|
|   |   |
|   |
|   |   |
|
|   | . |   |
|   |   |   |   |   |   |   |   |
|   |   |
|   |   |
|   |   |   |   | . | . |
|
|
|   |
|   |
|
|   |   |   |   |
|   |
|   |
|
|
|
|   |
|   |   |   |   |
|   |   |
|
Template Sequence |   |
. |
. |
. |
. |
. |
. |
. |
V | E | K | L | K | F | G | G | A | K | E | I | Y | L | T | E | R | G | T | . |
T | F | G | Y | N | N | L | V | V | D | F | R | S | L | P | I | M | K | Q | W | A | . |
. |
K | V | I | Y | D | A | T | H | S | V | Q | L | P | G | G | L | G | D | K | S | G | G | M | R | E | F | I | F | P | L |
Template Known Secondary structure |   |
. | . | . | . | . | . | . |  |  |  |  |  |  | T | T |
| S | S |  |  |  |  |  |
|
|  | . |  |
| S | T | T |
|  |  |
|
| T | T |  |  |  |  |  | T | T | T | S | . | . |  |  |  |  |  | T | T | G | G | G |  |  | T | T |
| S | S | S | S |
|  |  |
| G | G | G |  |  |  |  |
Template Predicted Secondary structure |   |
. | . | . | . | . | . | . |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
| . |
|
|
|
|
|  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |
| . | . |
|
|  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
|
|
|
|
|
|
1138 | . | 1140 | . | . | . | . | . | . | . | . | . | 1150 | . | . | . | . | . | . | |
. | . | . | 1160 | . | . | . | . | . | . | . | . | . | 1170 | . | . | . | . | . | . | . | |
|
. | . | 1180 | . | . | . | . | . | . | . | . | . | 1190 | . | . | . | . | . | . | . | . | . | 1200 | . | . | . | . | . | . | . |
  |
  |   |
286 | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
V | V | A | Q | I | K | D | G | N | R | S | I | I | G | L | M | I | E | S | N | I | H | E | G | N | Q | S | S | E | Q | P | R | S | E | M | K | Y | G | V | S | V | T | D | A | C | I | S | W | E | M | T | D | A | L | L | R | E | I | H | Q | D |
Query Conservation |   |
|   |   |
|   |   |   |   |   |   |   |
|   |
|
|
|
|
|
|
|
|   |   |
|   |
|   |   |   |   |   |   |   |   |
|   |   |
|   |
|
|
|
|   |
|
|   |
|   |   |
|
|   |
|
|   |   |
|
|
|   |
Alig confidence |   |
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |
|
|
|
|   | . | . | . |
|
|   |
|   |
|
|
|   |
|   |   |
|
|   |
|   |
|
|   |   |   | . | . | . | . | . | . | . | . | . | . | . | . |
|
|   |
|   |
|
|   |   |
|   |   |   |
|   |   |   |
Template Sequence |   |
I | R | A | A | V | A | V | . |
. |
. |
G | C | D | G | V | F | M | E | T | H | P | E | P | E | K | A | L | S | D | A | S | T | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Q | L | P | L | S | Q | L | E | G | I | I | E | A | I | L | E | I |
Template Known Secondary structure |   |
 |  |  |  |  |  |  | . | . | . |
|
| S |  |  |  |  |  |  |  | S | S | G | G | G |
| S | S |
| T | T | T | . | . | . | . | . | . | . | . | . | . | . | . |
|  |  | G | G | G |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  | . | . | . |
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
1208 | . | 1210 | . | . | . | . | |
|
|
. | . | . | . | . | 1220 | . | . | . | . | . | . | . | . | . | 1230 | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
. | . | . | 1240 | . | . | . | . | . | . | . | . | . | 1250 | . | . | . |
  |