|   |
44 | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | |
|
. | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . |
Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
| . | . |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
I | S | D | I | I | A | G | R | D | P | R | L | L | V | V | C | G | P | C | S | I | H | . |
. |
D | P | E | T | A | L | E | Y | A | R | R | F | K | A | L | A | A | E | V | S | D | S | L | Y | L | V | M | R | V | Y | F | E | K | P | R | T | T | V | G | W | K | G | L | I | N | D | P | H | M | D | G | S | F | D | V | E |
Query Conservation |   |
|   |   |
|
|   |
|   |
|   |
|
|
|
|
|   |
|
|
|
|
|   | . | . |
|   |   |   |   |
|
|
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|   |   |   |   |
|
|
|
|
|   |
|
|
|
|
|
|   |
|
|   |   |   |   |   |   |   |
|
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |   |   |   |
|
|   |   |   |   |   |   |
|
|
|
|
|
|   |
|
|   |
|
|
|   |   |
|   |   |
|
|   |   |
|   |   |
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|   |   |   |   |   |   |   |   |   |   |   | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |
|
Template Sequence |   |
I | A | N | K | T | V | G | K | D | A | P | V | F | I | I | A | E | A | G | I | N | H | D | G | K | L | D | Q | A | F | A | L | I | D | A | A | A | E | A | G | A | D | . |
. |
. |
. |
. |
A | V | K | F | Q | X | F | Q | A | D | R | X | Y | Q | K | D | P | . |
. |
. |
. |
D | V | S | I | F | S | L | V | Q | S | X | E |
Template Known Secondary structure |   |
 | T | T |  |  |  |  | T | T | S |
|
|  |  |  |  |  |  |  | T | T | T | T | T |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
| S | . | . | . | . | . |  |  |  |  |
|
| B |
| G | G | G | G | T | S |
|
|
| . | . | . | . |
|
|
|  |  |  |  | G | G | G | B | S |
Template Predicted Secondary structure |   |
 |
|
|  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
| . | . | . | . | . |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|  |  |  |  |  |  |  |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
6 | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | |
|
|
|
|
. | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | |
|
|
|
. | . | . | . | . | 70 | . | . | . | . | . | . |
  |
  |   |
122 | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | |
. | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  | . |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | G | L | Q | I | A | R | K | L | L | L | E | L | V | N | M | G | L | P | L | A | T | E | A | L | D | P | N | S | P | Q | Y | L | G | D | L | . |
F | S | W | S | A | I | G | A | R | T | T | E | S | Q | T | H | R | E | M | A | S | G | L | S | M | P | V | G | F | K | N | G | T | D | G | S | L | A | T | A | I | N | A |
Query Conservation |   |
  |
|
|   |   |   |
|   |
|   |   |   |   |   |
|   |
|
|
|
|
|
|
|   |
|
|   |   |   |   |   |
|   |   |
|
| . |
|   |   |   |   |
|
|
|
|
|   |
|
|
|   |
|
|
|   |
|
|
|
|   |   |
|
|
|
|
|
|   |
|   |
|   |
|   |   |
|
|   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |   |
|   |   |   |   |
|   |   |   |   |   |   |   |
|
|   |
|   |
|
|
|
|
|   |   |
|
|
|   |
|   |   |   |   |
|   |   |   |
|
|
|
|   |
|
|   |
|   |
|
|
|   |   |   |
|   |   |
|
|
|
|
|
|
|
|
|
| . |
|
|
|   |
|
|   |   |
|
Template Sequence |   |
X | P | A | E | W | I | L | P | L | L | D | Y | C | R | E | K | Q | V | I | F | L | S | T | V | C | D | E | G | S | A | D | L | L | Q | S | T | S | P | S | A | F | K | I | A | S | Y | E | I | N | H | L | P | L | L | K | Y | V | A | R | L | N | R | P | X | I | F | S | T | A | G | . |
A | E | I | S | D | V | H | E | A |
Template Known Secondary structure |   |
S |
| G | G | G |  |  |  |  |  |  |  |  |  |  | T | T |
|  |  |  |
| B |
|
| S |  |  |  |  |  |  |  |  | T | T |
|
| S |
|  |  |  |
| G | G | G | T | T |
|  |  |  |  |  |  |  |  | T | T |
| S |
|  |  |  |  |
| T | T | . |
|
|  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
| . |
|
|  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
86 | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | |
. | . | . | . | 160 | . | . | . | . |
  |
  |   |
201 | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | |
|
. | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  | . | . |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
M | R | A | A | A | Q | P | H | R | F | V | G | I | N | Q | A | G | Q | V | A | L | L | Q | T | Q | G | N | P | D | G | H | V | . |
. |
I | L | R | G | G | K | A | P | N | Y | S | P | A | D | V | A | Q | C | E | K | E | M | E | Q | A | G | L | R | P | S | L | M | V | D | C | S | H | G | N | S | N | K | D | Y | R | R |
Query Conservation |   |
|   |
|
|   |   |   |
|   |
|
|   |
|   |   |   |
|   |   |   |   |
|   |
|   |
|
|   |   |   |
|
| . | . |
|
|
|
|
|   |   |
|
|
|   |   |   |   |
|   |   |   |   |   |   |
|   |
|   |   |   |   |   |   |
|
|
|
|   |
|
|
|
|
|   |
|   |   |   |   |
Alig confidence |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
Template Conservation |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|   |   |
|   |   |   |
|   |   |   |
|   |
|
|
|
|   |
|   |
|
|   |
|   | . | . | . |   |   |   |
|
|   |   |
|   |   |
|   |   |   |
|   |   |   |   |
|
|   |
|
|
|
|   |
|   | . | . | . | . | . |
Template Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
W | R | T | I | R | A | E | G | N | N | Q | I | A | I | X | H | C | V | A | K | Y | P | A | P | P | . |
. |
. |
E | Y | S | N | L | S | V | I | P | X | L | A | A | A | F | P | E | A | V | I | G | F | S | D | H | S | E | H | P | . |
. |
. |
. |
. |
Template Known Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  | T | T | T |
|
|
|  |  |  |  |  |  |
| S | S | S | S |
|
| G | . | . | . | G | G |
|
| T | T |  |  |  |  |  |  |  |  | S | T | T | S |  |  |  |  |  |  |
|
| S | S | S | . | . | . | . | . |
Template Predicted Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|  | . | . | . |  |  |
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |
|
|
|
|
|
|
|
|
| . | . | . | . | . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
165 | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | |
|
|
190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | |
|
|
|
|
  |
  |   |
279 | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | |
|
. | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
| . | . |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
Q | P | A | V | A | E | S | V | V | A | Q | I | K | D | G | N | R | S | I | I | G | L | M | I | E | S | N | I | H | E | G | N | Q | S | S | E | Q | P | R | S | E | M | K | Y | G | V | S | V | T | D | . |
. |
A | C | I | S | W | E | M | T | D | A | L | L | R | E | I | H | Q | D | L | N | G | Q |
Query Conservation |   |
|
|   |
|   |   |   |
|   |   |
|   |   |   |   |   |   |   |
|   |
|
|
|
|
|
|
|
|   |   |
|   |
|   |   |   |   |   |   |   |   |
|   |   |
|   |
|
|
|
| . | . |   |
|
|   |
|   |   |
|
|   |
|
|   |   |
|
|
|   |
|   |   |   |
Alig confidence |   |
. | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
| . | . | . | . | . | . | . | . | . | . | . |
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
. | . | . | . |   |   |   |   |   |
|
|
|
|
|
|
|   | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|   |   |   | . |
|   | . | . | . | . | . | . | . | . | . | . | . |
|
|   |   |
|
|   |
|   |
|
|   |   |
|
|   |   |
|
|   |   |   |   |
|
|
Template Sequence |   |
. |
. |
. |
. |
T | E | A | P | C | A | A | V | R | L | G | A | K | . |
. |
. |
. |
. |
L | I | E | K | H | F | T | I | D | K | N | L | P | . |
G | A | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
D | H | S | F | A | L | N | P | D | E | L | K | E | X | V | D | G | I | R | K | T | E | A | E | L |
Template Known Secondary structure |   |
. | . | . | . | S |  |  |  |  |  |  |  |  | T | T |
| S | . | . | . | . | . |  |  |  |  |  | B |
| S |
| T | T | S | S | . |
| S | . | . | . | . | . | . | . | . | . | . | . | S |
| T | T | S | B |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
. | . | . | . |
|  |  |  |  |  |  |  |  |
|
|
|  | . | . | . | . | . |  |  |  |  |  |  |
|
|
|
|
|
|
| . |
|
| . | . | . | . | . | . | . | . | . | . | . |
|  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
|
|
|
219 | 220 | . | . | . | . | . | . | . | . | . | 230 | . | |
|
|
|
|
. | . | . | . | . | . | . | . | 240 | . | . | . | . | |
. | . | |
|
|
|
|
|
|
|
|
|
|
. | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . |
  |