Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	N	I	S	Y	V	N	S	N	K	T	T	S	L	P	V	E	L	D	A	L	N	N	K	D	I	S	Y	A	K	D	F	F	L	Y	I	E	T	Q	L	K	I	A	K	D	F	L	D	L	E	K	K	Y	Q	V	L	L	Q	V	K
Secondary structure
SS confidence
Disorder		?	?	?	?			?				?													?
Disorder confidence
		.	.	.	.	.	.	.
Sequence		F	F	T	H	L	L	I
Secondary structure
SS confidence
Disorder				?	?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 3fcn chain A Region: 27 - 50 Aligned: 24 Modelled: 24 Confidence: 11.2% Identity: 38% PDB header:unknown function Chain: A: PDB Molecule:an alpha-helical protein of unknown function (pfam01724); PDBTitle: crystal structure of an alpha-helical protein of unknown function2 (rru_a3208) from rhodospirillum rubrum atcc 11170 at 1.45 a3 resolution Phyre2 PDB 3owt chain C Region: 49 - 57 Aligned: 9 Modelled: 9 Confidence: 8.9% Identity: 67% PDB header:protein binding Chain: C: PDB Molecule:regulatory protein sir3; PDBTitle: crystal structure of s. cerevisiae rap1-sir3 complex Phyre2 PDB 1hs7 chain A Region: 41 - 56 Aligned: 16 Modelled: 16 Confidence: 6.9% Identity: 50% Fold: STAT-like Superfamily: t-snare proteins Family: t-snare proteins Phyre2 PDB 2ae8 chain C Region: 37 - 66 Aligned: 28 Modelled: 28 Confidence: 5.8% Identity: 32% PDB header:lyase Chain: C: PDB Molecule:imidazoleglycerol-phosphate dehydratase; PDBTitle: crystal structure of imidazoleglycerol-phosphate dehydratase from2 staphylococcus aureus subsp. aureus n315 Phyre2 1 c3fcnA_ 2 c3owtC_ 3 d1hs7a_ 4 c2ae8C_

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c3fcnA_ 11.2 38 PDB header:unknown function Chain: A: PDB Molecule:an alpha-helical protein of unknown function (pfam01724); PDBTitle: crystal structure of an alpha-helical protein of unknown function2 (rru_a3208) from rhodospirillum rubrum atcc 11170 at 1.45 a3 resolution 2 c3owtC_ 8.9 67 PDB header:protein binding Chain: C: PDB Molecule:regulatory protein sir3; PDBTitle: crystal structure of s. cerevisiae rap1-sir3 complex 3 d1hs7a_ 6.9 50 Fold:STAT-like Superfamily:t-snare proteins Family:t-snare proteins 4 c2ae8C_ 5.8 32 PDB header:lyase Chain: C: PDB Molecule:imidazoleglycerol-phosphate dehydratase; PDBTitle: crystal structure of imidazoleglycerol-phosphate dehydratase from2 staphylococcus aureus subsp. aureus n315

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0