|   |
340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | |
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |
|
|
|
|
|
|  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . |  |  |
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
S | N | L | G | I | G | D | I | I | Y | Q | S | Q | A | M | E | D | L | L | Q | Q | V | D | I | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
V | A | K | S | D | S | T | V | L | I | C | G | E | T | G | T | G | K | E | V | I | A | R | A | I | H | Q | L | S | P | R | R | D | K | P | L | V | K | I | N | C | A | A | I | P |
Query Conservation |   |
  |   |   |   |   |   |   |
|
|
|   |
|   |   |   |   |   |   |   |   |   |
|   |   | . | . | . | . | . | . | . | . | . | . | . |   |
|   |   |   |   |
|
|
|
|   |
|
|   |
|
|
|
|   |   |   |
|   |   |
|
|   |   |
|   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
| . | . | . | . |
Template Conservation |   |
  |   |
|   |   |   |
|
|
|
|
|   |   |
|
|   |   |
|   |
|   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |
|
|
|
|   |
|
|
|
|
|
|
|
|   |
|
|   |
|
|
|   |   |   | . | . | . |   |   |   |   |   |   |
|   |   | . | . | . | . |
Template Sequence |   |
P | Q | V | T | W | E | D | I | G | G | L | E | D | V | K | R | E | L | Q | E | L | V | Q | Y | P | V | E | H | P | D | K | F | L | K | F | G | M | T | P | S | K | G | V | L | F | Y | G | P | P | G | C | G | K | T | L | L | A | K | A | I | A | N | E | C | . |
. |
. |
Q | A | N | F | I | S | I | K | G | . |
. |
. |
. |
Template Known Secondary structure |   |
|
|
|
| T | T | T | T |
| S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  |  |  |  |  | T | S |
|
|
|
|
| S |
|  |  |  |  |
|
| T | T | S |
|  |  |  |  |  |  |  |  |  |  |  | T | . | . | . | T |
|  |  |  |  |
|
|  | . | . | . | . |
Template Predicted Secondary structure |   |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  | . | . | . |
|
|
|  |  |  |  |  |  | . | . | . | . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
472 | . | . | . | . | . | . | . | 480 | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . | . | . | . | . | 510 | . | . | . | . | . | . | . | . | . | 520 | . | . | . | . | . | . | . | . | . | 530 | . | . | . | . | . | |
|
|
. | . | . | . | 540 | . | . | . | . | |
|
|
|
  |
  |   |
409 | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|  |  |  |  |  |
|  |  |  |
|
|  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | S | L | L | E | S | E | L | F | G | H | D | K | G | A | F | T | G | A | I | N | T | H | R | G | R | F | E | I | A | D | G | G | T | L | F | L | D | E | I | G | D | L | P | L | E | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
L | Q | P | K | L | L | R | V | L | Q | E | R | E | I | E | R | L | G | G | S |
Query Conservation |   |
  |   |   |   |   |   |   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|   |   |
|
|
|   |
|   |   |
|   |   |
|   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |
|   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
. | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . |
Template Conservation |   |
. | . | . | . | . |   |   |
|   |   |   |   |
|
|   |
|
|   |   |
|   |   |   |
|   |   |
|   |   |   |   |
|   |
|
|
|   |
|
|
|
|   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |
|
|
| . | . | . | . | . | . | . | . | . |
Template Sequence |   |
. |
. |
. |
. |
. |
P | E | L | L | T | M | W | F | G | E | S | E | A | N | V | R | E | I | F | D | K | A | R | Q | A | A | P | C | V | L | F | F | D | E | L | D | S | I | A | K | A | R | G | G | N | I | G | D | G | G | G | A | A | D | R | V | I | N | Q | I | L | T | E | M | D | G | . |
. |
. |
. |
. |
. |
. |
. |
. |
Template Known Secondary structure |   |
. | . | . | . | . |  |  |  |  |  |  |  | T | T | T |
| T |  |  |  |  |  |  | T | T | T | T | T | T | T |
| S |  |  |  |  |
| S | S | G | G | G | G |  |  |  |  | T | T | T | T |
| S | S |
|
| S |
|
|  |  |  |  |  |  |  |  |  |  |  | S | . | . | . | . | . | . | . | . | . |
Template Predicted Secondary structure |   |
. | . | . | . | . |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
| . | . | . | . | . | . | . | . | . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
|
|
|
|
545 | . | . | . | . | 550 | . | . | . | . | . | . | . | . | . | 560 | . | . | . | . | . | . | . | . | . | 570 | . | . | . | . | . | . | . | . | . | 580 | . | . | . | . | . | . | . | . | . | 590 | . | . | . | . | . | . | . | . | . | 600 | . | . | . | . | . | . | . | . | . | 610 | |
|
|
|
|
|
|
|
|
  |
  |   |
475 | . | . | . | . | 480 | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . | . | |
|
. | . | . | |
510 | . | . | . | . | . | . | . | . | . | 520 | . | . | . | . | . | . | . | . | . | 530 | . | . | . | . | . | . | . | . | . | 540 | . | . | . | . | . | . | . | . | . | 550 | . |
Predicted Secondary structure |   |
|  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  | . | . |  |
|
| . |  |  |  |  |  |
|
|
|  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
R | T | I | P | V | N | V | R | V | I | A | A | T | N | R | D | L | W | Q | M | V | E | D | R | Q | F | R | S | D | L | F | Y | . |
. |
R | L | N | . |
V | F | P | L | E | L | P | P | L | R | D | R | P | E | D | I | P | L | L | A | K | H | F | T | Q | K | M | A | R | H | M | N | R | A | I | D | A | I | P | T | E | A |
Query Conservation |   |
  |   |   |   |   |   |   |
|   |
|   |   |
|   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |
|   |   | . | . |   |
|   | . |   |   |   |
|   |
|
|
|
|
|
|
|   |
|
|
|   |   |
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
| . | . |
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |
|   |
|
|   |
|
|
|   | . | . | . | . | . | . | . |   |   |   |
|
|   |
|
|   |
|
|
|
|
|
|   |   |
|   |   |   |   |
|   |   |   |   |
|   |   | . | . | . | . |
|   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |
Template Sequence |   |
M | S | T | K | K | N | V | F | I | I | G | A | T | N | R | . |
. |
. |
. |
. |
. |
. |
P | D | I | I | D | P | A | I | L | R | P | G | R | L | D | Q | L | I | Y | I | P | L | P | D | E | K | S | R | V | A | . |
. |
. |
. |
I | L | K | A | N | L | R | K | S | . |
. |
. |
. |
. |
. |
. |
. |
. |
P | V | A | K | D | V |
Template Known Secondary structure |   |
S |
| T | T | S | S |
|  |  |  |  |  |  | S |
| . | . | . | . | . | . | . | G | G | G |
|
| G | G | G | T | S | T | T | T | S |
|  |  |  |  |
|
|
|
|
| T | T |  |  |  |  | . | . | . | . |  |  |  |  |  | T | T | T | S | . | . | . | . | . | . | . | . | . |
| B |
| S | S |
|
Template Predicted Secondary structure |   |
|
|
|
|
|
|  |  |  |  |  |  |
|
|
| . | . | . | . | . | . | . |  |  |  |
|
|  |  |  |
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  | . | . | . | . |  |  |  |  |  |  |
|
|
| . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
611 | . | . | . | . | . | . | . | . | 620 | . | . | . | . | . | |
|
|
|
|
|
|
. | . | . | . | 630 | . | . | . | . | . | . | . | . | . | 640 | . | . | . | . | . | . | . | . | . | 650 | . | . | . | . | . | |
|
|
|
. | . | . | . | 660 | . | . | . | . | |
|
|
|
|
|
|
|
|
. | . | . | . | . | 670 |
  |
  |   |
|
552 | . | . | . | . | . | . | . | 560 | . | . | . | . | . | . | . | . | . | 570 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
. |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
Query SS confidence |   |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
. |
L | R | Q | L | M | S | W | D | W | P | G | N | V | R | E | L | E | N | V | I | E | R | A | V | L | L | T |
Query Conservation |   |
. |   |   |   |
|   |   |
|   |
|
|
|
|
|   |
|
|   |   |
|
|   |   |   |   |   |   |   |
Alig confidence |   |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |
|
|   |   |   |   |
|   |
|
|
|
|
|   |   |   |   |   |   |
|   |   |   |
|
Template Sequence |   |
D | L | E | F | L | A | K | M | T | N | G | F | S | G | A | D | L | T | E | I | C | Q | R | A | C | K | L | A |
Template Known Secondary structure |   |
|  |  |  |  | T | T | T |
| S | S |
|
|  |  |  |  |  |  |  |  |  |  |  |  | T | T |  |
Template Predicted Secondary structure |   |
|  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
671 | . | . | . | . | . | . | . | . | 680 | . | . | . | . | . | . | . | . | . | 690 | . | . | . | . | . | . | . | . |
  |