|   |
383 | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | Q | V | L | I | E | A | V | K | H | H | P | R | S | K | Y | V | S | L | L | T | N | W | C | G | E | H | S | S | Q | E | A | R | R | L | F | S | E | A | G | L | P | T | Y | R | T | P | E | G | T | I | T | A | F | M | H | M | V | E | Y | R | R | N | Q | K | Q | L | R | E | T | P | A | L | P | S | N | L | T | S | N |
Query Conservation |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|   |   |   |   |
|   |   |   |   |   |   |   |
|   |   |
|   |   |
|
|
|
|   |
|   |
|
|
|   |
|
|   |
|   |   |   |
|   |   |
|   |   |   |   |   |   |
|   |   |
|
|   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Conservation |   |
  |   |   |
|   |   |   |   |   |   |   |   | . | . | . | . |   |
|   |
|
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|
|   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Sequence |   |
I | P | A | L | L | D | F | A | Q | N | E | K | . |
. |
. |
. |
I | D | L | T | I | V | G | P | E | A | P | L | V | K | G | V | V | D | T | F | R | A | A | G | L | K | I | F | G | P | T | A | G | A | A | Q | L | E | G | S | K | A | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  | T | T | . | . | . | . |
| S |  |  |  |  |
| S |  |  |  |  |  | T | T |  |  |  |  |  |  |  | T | T |
|
|  |  | S |
|
| T | T | T | T |  |  |  |  |
|  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |
| . | . | . | . |
|
|  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
53 | . | . | . | . | . | . | 60 | . | . | . | . | |
|
|
|
. | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |
  |   |
463 | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480 | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . | . | . | . | . | 510 | . | . | . | . | . | . | . | . | . | 520 | . | . | . | . | . | . | . | . | . | 530 | . | . | . | . | . | . | . | . | . | 540 | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
T | A | E | A | H | L | L | L | Q | Q | A | I | A | E | G | A | T | S | L | D | T | H | E | V | Q | P | I | L | Q | A | Y | G | M | N | T | L | P | T | W | I | A | S | D | S | T | E | A | V | H | I | A | E | Q | I | G | Y | P | V | A | L | K | L | R | S | P | D | I | P | H | K | S | E | V | Q | G | V | M | L | Y | L |
Query Conservation |   |
  |   |   |
|   |   |   |
|   |   |
|
|   |   |   |   |   |   |
|   |
|   |
|
|
|   |
|
|   |
|
|
|
|
|
|   |   |   |   |   |
|   |
|   |
|
|
|   |   |
|
|   |   |
|
|   |
|
|
|
|
|   |   |
|   |   |
|   |
|
|
|
|   |
|
|
|   |
|   |
|
Alig confidence |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
| . |
|
Template Conservation |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |
|   |   |   |
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |
| . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   | . |   |
Template Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
F | T | K | D | F | L | A | R | H | K | I | P | T | A | E | Y | Q | N | F | T | E | V | E | P | A | L | A | Y | L | R | E | K | G | A | P | I | V | I | K | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
A | K | G | V | I | V | . |
A |
Template Known Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  | T | T |
|
| B |
|
|  |  |  |  | S | S | S | S |  |  |  |  |  |  |  |  |  |
| S | S |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . |
|
|
|  |  |  | . |  |
Template Predicted Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . |
|
|
|  |  |  | . |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
107 | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
. | . | . | . | 150 | . | |
. |
  |
  |   |
543 | . | . | . | . | . | . | 550 | . | . | . | . | . | . | . | . | . | 560 | . | . | . | . | . | . | . | . | . | 570 | . | . | . | . | . | . | . | . | . | 580 | . | . | . | . | . | . | . | . | . | 590 | . | . | . | . | . | . | . | . | . | 600 | |
|
|
|
|
|
|
. | . | . | . | . | . | . | . | . | 610 | . | . | . | . | . |
Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  | . | . | . | . | . | . | . |  |  |
|
|
|
|
|  |  |  |
|
|
|
|  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
R | T | A | N | E | V | Q | Q | A | A | N | A | I | F | D | R | V | K | M | A | W | P | Q | A | R | V | H | G | L | L | V | Q | S | M | A | N | R | A | G | A | Q | E | L | R | V | V | V | E | H | D | P | V | F | G | P | L | I | M | . |
. |
. |
. |
. |
. |
. |
L | G | E | G | G | V | E | W | R | P | E | D | Q | A | V |
Query Conservation |   |
  |
|   |
|   |
|   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |
|   |   |   |
|   |
|
|
|
|
|   |
|   |   |   |   |   |   |   |
|
|   |
|
|
|   |   |
|
|   |
|
|
|
|
|   | . | . | . | . | . | . | . |   |
|   |
|
|   |   |
|
|   |   |   |
|   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . |   |
|
|
|
|   |
| . | . | . |   |
|   |
|   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
M | T | L | E | E | A | E | A | A | V | H | D | M | L | A | G | N | A | F | G | D | A | G | H | R | . |
. |
. |
I | V | I | E | E | F | L | . |
. |
. |
D | G | E | E | A | S | F | I | V | M | V | D | G | E | H | V | L | P | M | A | T | S | Q | D | H | K | R | V | G | D | K | D | T | G | P | N | T | G | G | M | G | A |
Template Known Secondary structure |   |
S | S |  |  |  |  |  |  |  |  | T | T | T | T |
| S |
|
| T | T |
| T | T |
|
| . | . | . |  |  |  |  |  |
|
| . | . | . |
|  |  |  |  |  |  |  |  |  |  |  | S | S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | T |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  | . | . | . |  |  |  |  |  |  |  | . | . | . |
|
|  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
159 | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | |
|
|
. | . | . | . | . | . | 190 | |
|
|
. | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . |
  |
  |   |
616 | . | . | . | 620 | . | . | . | . | . | . | . | . | . | 630 | . | . | . | . | . | . | . | . | . | 640 |
Predicted Secondary structure |   |
 |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
V | A | L | P | P | L | N | M | N | L | A | R | Y | L | V | I | Q | G | I | K | S | K | K | I | R |
Query Conservation |   |
  |   |
|
|
|
|   |   |   |
|
|   |   |
|
|   |   |   |   |   |   |   |
|
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
Template Sequence |   |
Y | S | P | A | P | V | V | T | D | D | V | H | Q | R | T | M | E | R | I | I | W | P | T | V | K |
Template Known Secondary structure |   |
 |  | S |
| T | T |
|
|  |  |  |  |  |  |  |  |  |  | T |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
233 | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . |
  |