|   |
25 | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
. | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . |
Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |
|
|  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
K | C | E | M | N | V | G | V | Y | L | P | P | K | A | A | N | E | K | L | P | V | L | Y | W | L | S | G | L | T | C | N | E | Q | N | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
F | I | T | K | S | G | M | Q | R | Y | A | A | E | H | N | I | I | V | V | A | P | D | T | S | P | R | G | S | H | V | A | D | A |
Query Conservation |   |
|   |   |   |   |   |   |
|
|
|
|   |   |   |   |   |   |   |   |
|
|
|   |   |
|
|
|   |
|   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |
|   |
|   |   |   |
|   |   |   | . | . |   |   |   |   |
|   |
|
|
|   |
|
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|   |   |
|   |   |
|   |
|   |
|   |   |   |   |
Template Sequence |   |
P | V | V | I | A | Y | E | T | Y | G | T | L | S | . |
. |
S | S | K | N | N | A | I | L | I | C | H | A | L | S | G | D | A | H | A | A | G | Y | H | S | G | S | D | K | K | P | G | W | W | D | D | Y | I | G | P | G | K | S | F | D | T | N | Q | Y | F | I | I | C | S | N | V | I | G | G | C | K | G | S | S | G | P |
Template Known Secondary structure |   |
S |  |  |  |  |  |  |  |  |  |
|
|
| . | . | T | T | S |
|
|  |  |  |  |  |
|
| S | S |
|
| S |
|
| S | S | B | S | S | T | T |
| S | S |
|
| T | T | T | T | T |  |  | T | T | S | S |  |  | T | T | T |
|  |  |  |  |  |
|
| T | T |
| S | S | S | S | S | S | T |
Template Predicted Secondary structure |   |
|  |  |  |  |  |  |  |
|
|
|
|
| . | . |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
30 | . | . | . | . | . | . | . | . | . | 40 | . | . | |
|
. | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . |
  |
  |   |
92 | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
D | R | Y | D | L | G | Q | G | A | G | F | Y | L | N | A | T | Q | A | P | W | N | E | H | Y | K | M | Y | D | Y | I | R | N | E | L | P | D | L | V | M | H | H | F | P | A | T | A | K | K | S | I | S | G | H | S | M | G | G | L | G | A | L | V | L | A | L | R | N | P | D | E | Y | V | S | V | S | A | F | S | P | I |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |
|   |
|
|   |   |
|
|   |   |   |   |   |   |
|   |   |
|   |   |
|   |
|   |
|
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |
|   |
|   |   |   |   |   |
|
|   |   |
| . | . | . | . | . | . | . | . |
|   |   |   |   |   |   |
|   |
|
|
|   |
|
|   |
|
|   |   |   |
|   |   |   |
|   |   |
|   |   |
|
|
|   |   |   |   |
Template Sequence |   |
L | S | I | H | P | E | T | S | T | P | Y | G | S | R | F | P | F | V | S | I | Q | D | M | V | K | A | Q | K | L | L | V | E | S | L | . |
. |
. |
. |
. |
. |
. |
. |
G | I | E | K | L | F | C | V | A | G | G | S | M | G | G | M | Q | A | L | E | W | S | I | A | Y | P | N | S | L | S | N | C | I | V | M | A | S | T |
Template Known Secondary structure |   |
T | S | B |
| T | T | T | S | S | B |
| G | G | G | S |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | . | . | . | . | . | . | . | . | T |
| S | S |  |  |  |  |  |  |  | T |  |  |  |  |  |  |  |  |  |  |  |  | S | T | T | S |  |  |  |  |  |  |  | S |
|
|
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| . | . | . | . | . | . | . | . |
|
|
|
|  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
108 | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | |
|
|
|
|
|
|
|
. | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . |
  |
  |   |
172 | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
V | S | P | S | Q | V | P | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
W | G | Q | Q | A | F | A | A | Y | L | A | E | N | K | D | A | W | L | D | Y | D | P | V | S | L | I | S |
Query Conservation |   |
  |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
A | E | H | S | A | M | Q | I | A | F | N | E | V | G | R | Q | A | I | L | S | D | P | N | W | K | N | G | L | Y | D | E | N | S | P | R | K | G | L | A | L | A | R | M | V | G | H | I | T | Y | L | S | D | D | K | M | R | E | K | F | G | R | N | P | P | R | G | N | I | L | S | T | D | F | A | V | G | S | Y | L | I |
Template Known Secondary structure |   |
S | B |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | S | T | T |
| G | G | G | T |
| S | S | S |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | B |
|  |  |  |  |  |  |  |  | T | T | S |
|
| S | S |
| T | T | T | T | T | T | T | S |
| G | G | G | G |
Template Predicted Secondary structure |   |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . |
  |
  |   |
206 | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
Query SS confidence |   |
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
Q | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
G | Q | R | V | A | E | I | M | V | D | Q | G | L | S | D | D | F | Y | A | E | Q | L | R | T | P | N | L | E | K | I | C | Q | E | M | N | I | K | T | L | I | R | Y | H |
Query Conservation |   |
  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |
|   |   |
|   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |
Alig confidence |   |
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |
|
|
|
|
|   |
|   |   |
|   |   |   |
|   |   | . |   |   |   |   |
|   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |
|
Template Sequence |   |
Y | Q | G | E | S | F | V | D | R | F | D | A | N | S | Y | I | Y | V | T | K | A | L | D | H | Y | S | L | G | K | G | K | E | L | T | A | A | L | S | N | A | T | C | R | F | L | V | V | S | Y | S | S | D | W | L | Y | P | P | A | . |
Q | S | R | E | I | V | K | S | L | E | A | A | D | K | R | V | F | Y | V | E | L |
Template Known Secondary structure |   |
S | T | T |
|
| S | S | S |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
| B |
|
| S |  |  |  |  |  |  |  |  | T | T |
|
| S |  |  |  |  |  |  |  | T | T |
|
| S | S |
|  |  | . |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
|  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|  |  | . |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | |
. | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . |
  |
  |   |
|
250 | . | . | . | . | . | . | . | . | . | 260 | . | |
. | . | . | . | . | . | . | . | 270 | . | . | . | . | . |
Predicted Secondary structure |   |
. |
|
|
|
|
|
|  |  |  |  |  |  | . |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
Query SS confidence |   |
. |
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
. |
E | G | Y | D | H | S | Y | Y | F | V | S | S | . |
F | I | G | E | H | I | A | Y | H | A | N | K | L | N |
Query Conservation |   |
. |   |
|   |   |
|   |   |   |   |   |   |   | . |   |   |   |   |   |
|   |   |   |   |   |   |
|   |
Alig confidence |   |
. |
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |
|
|   |   |   |
|
|   |
|
|   |
|   |   |   |
|   |   |
|
|   |   |
|   |
Template Sequence |   |
Q | S | G | E | G | H | D | S | F | L | L | K | N | P | K | Q | I | E | I | L | K | G | F | L | E | N | P | N |
Template Known Secondary structure |   |
|
|
| B | S | S | G | G | G | G | S |
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
339 | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . |
  |