|   |
18 | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |
|  |  |  |
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
R | H | Y | S | Q | S | L | K | C | E | M | N | V | G | V | Y | L | P | P | K | A | A | N | E | K | L | P | V | L | Y | W | L | S | G | L | T | C | N | E | Q | N | F | I | T | K | S | G | M | Q | R | Y | A | A | E | H | N | I | I | V | V | A | P | D | T | S | P | R | G | S | H | V | A | D | A | D | R | Y | D | L | G |
Query Conservation |   |
  |   |   |
|   |   |   |
|   |   |   |   |   |   |
|
|
|
|   |   |   |   |   |   |   |   |
|
|
|   |   |
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . |
Template Conservation |   |
  |   |   |
|   |   |   |   |
|   |   |   |   |   |   |   |
|   |   |   |
| . | . | . | . | . |
|   |
|
|
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
| . | . | . | . |   |   |   |   |   |
|
|   |   |
|
|   |
|   |
|   |
|   | . | . | . | . | . | . | . | . | . |
Template Sequence |   |
S | F | Y | I | S | T | R | F | G | Q | T | H | V | I | A | S | G | P | E | D | A | . |
. |
. |
. |
. |
P | P | L | V | L | L | H | G | A | L | F | S | S | T | X | W | Y | P | N | I | A | D | W | . |
. |
. |
. |
S | S | K | Y | R | T | Y | A | V | D | I | I | G | D | K | N | K | S | . |
. |
. |
. |
. |
. |
. |
. |
. |
Template Known Secondary structure |   |
 |  |  |  |  |  | T | T |  |  |  |  |  |  |  |  | S |
| T | T | S | . | . | . | . | . |
|  |  |  |  |  |
|
| T | T | T |
| G | G | G | G | T | T | T |  |  |  |  | . | . | . | . | T | T | T | S |  |  |  |  |  |
|
| T | T | S | S | S | S |
| . | . | . | . | . | . | . | . | . |
Template Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
| . | . | . | . | . |
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  | . | . | . | . |  |
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
35 | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | |
|
|
|
|
. | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | |
|
|
|
. | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
  |
  |   |
98 | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
Q | G | A | G | F | Y | L | N | A | T | Q | A | P | W | N | E | H | Y | K | M | Y | D | Y | I | R | N | E | L | P | D | L | V | M | H | H | F | P | A | T | A | K | K | S | I | S | G | H | S | M | G | G | L | G | A | L | V | L | A | L | R | N | P | D | E | Y | V | S | V | S | A | F | S | P | I | V | S | P | S | Q | V |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |
|   |
|
|   |   |
|
|   |   |   |   |   |   |
|   |   |
|   |   |
|   |
|   |
|
|   |   |   |   |   |   |   |
Alig confidence |   |
. | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
. | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . |   |   |   |   |   |   |   |   |
|   |
|   |
|
|   |
|
|   |   |   |
|   |   |   |   |   |   |   |   |   |
|
|
|   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
I | P | E | N | V | S | G | T | R | T | D | Y | A | N | W | L | L | D | V | F | D | N | L | . |
. |
G | I | E | K | S | H | X | I | G | L | S | L | G | G | L | H | T | X | N | F | L | L | R | X | P | E | R | V | K | S | A | A | I | L | S | P | A | E | T | F | L | P | F |
Template Known Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . |  |  |
| S |
|
|
| B |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | T |
| S | S |  |  |  |  |  |  | T |  |  |  |  |  |  |  |  |  |  |  |  |
| G | G | G |  |  |  |  |  |  |  | S |
| S | S | B | T | S |
|
|
Template Predicted Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
| . | . |
|
|  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
|
|
|
|
|
|
|
|
|
|
|
97 | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | |
|
120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . |
  |
  |   |
178 | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
P | W | G | Q | Q | A | F | A | A | Y | L | A | E | N | K | D | A | W | L | D | Y | D | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
P | V | S | L | I | S | Q | G | Q | R | V | A | E | I | M | V | D | Q | G |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |
|   |
|   |
|   |
|
Template Sequence |   |
H | H | D | F | Y | K | Y | A | L | G | L | T | A | S | N | G | V | E | T | F | L | N | W | X | X | N | D | Q | N | V | L | H | P | I | F | V | K | Q | F | K | A | G | V | X | W | Q | D | G | S | R | N | P | N | P | N | A | D | G | F | P | Y | V | F | T | D | E | E | L | R | S | A | R | V | P | I | L | L | L | L | G |
Template Known Secondary structure |   |
|  |  |  |  |  |  |  |  | T | T | T | S | T | T |  |  |  |  |  |  |  |  |  | T | T | T |
|
|
| S |
|  |  |  |  |  |  |  |  |  |  |  |  |
|
| S | S | S |
|
|
|
|
|
| T | T | B | S | S |
| B |
|
|  |  |  |  |  | T |
|
| S |
|  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
163 | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . |
  |
  |   |
219 | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
L | S | D | D | F | Y | A | E | Q | L | R | T | P | N | L | E | K | I | C | Q | E | M | N | I | K | T | L | I | R | Y | H | E | G | Y | D | H | S | Y | Y | F | V | S | S | F | I | G | E | H | I | A | Y | H | A | N | K | L | N |
Query Conservation |   |
  |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |
|   |   |   |   |   |   | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|
| . | . |   |   |   |   |
|   |
|   |   |
|   |   |   |
|   |   |
|
|   |
Template Sequence |   |
E | H | E | V | I | Y | D | P | H | . |
. |
. |
. |
S | A | L | H | R | A | S | S | F | V | P | D | I | E | A | E | V | I | K | N | A | G | H | . |
. |
V | L | S | X | E | Q | P | T | Y | V | N | E | R | V | X | R | F | F | N |
Template Known Secondary structure |   |
T | T |
|
| S | S |
|  |  | . | . | . | . |  |  |  |  |  |  |  |  |  | S | T | T |
|  |  |  |  |  | T | T |
|
| T | . | . | T |  |  |  |  | S |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|  |  | . | . | . | . |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
| . | . |
|
|  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
243 | . | . | . | . | . | . | 250 | . | |
|
|
|
. | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | |
|
. | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . |
  |