|   |
182 | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | |
|
|
. | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | I | T | T | H | G | D | E | L | A | A | V | L | F | T | S | G | T | E | G | L | P | K | G | V | M | L | T | H | N | N | I | L | A | S | E | R | A | Y | C | A | R | L | N | . |
. |
. |
L | T | W | Q | D | V | F | M | M | P | A | P | L | G | H | A | T | G | F | L | H | G | V | T | A | P | F | L | I | G | A | R | S |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|
|
|
|
|   |
|
|   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
Template Sequence |   |
X | F | A | V | P | Q | D | R | I | S | R | I | H | A | S | S | G | T | T | G | K | P | T | V | V | G | Y | T | A | A | D | I | D | T | W | A | N | L | V | A | R | S | I | R | A | A | G | A | R | R | G | D | K | V | H | V | S | Y | G | Y | G | L | F | T | G | G | L | G | A | H | Y | G | A | E | R | A | G | L | T | V |
Template Known Secondary structure |   |
T |
|
| S |
| G | G | G |
|
|  |  |  |  |
|
|
| S | S | S | S |
|
|  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
| T | T |
|  |  |  |  |
| S |
|
| S | S | S |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|  |  |
Template Predicted Secondary structure |   |
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
79 | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . |
  |
  |   |
259 | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | |
|
. | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | |
. | . | . | . | 330 | . | . | . | . | . |
Predicted Secondary structure |   |
 |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
| . | . |
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  | . |
|
|
|  |  |  |  |  |  |
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
V | L | L | D | I | F | T | P | D | A | C | L | A | L | L | E | Q | Q | R | C | T | C | M | L | G | A | T | P | F | V | Y | D | L | L | N | V | L | E | K | Q | P | A | D | L | . |
. |
S | A | L | R | F | F | L | C | G | G | T | T | I | P | K | K | V | A | R | E | C | Q | Q | . |
R | G | I | K | L | L | S | V | Y | G |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . |   |   |   |   |   |   |   |   |
|
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|
|
Template Sequence |   |
I | P | F | G | G | G | Q | T | E | K | Q | V | Q | L | I | Q | D | F | R | P | D | I | I | X | V | T | P | S | Y | X | L | S | I | A | D | E | I | E | R | Q | G | L | D | P | V | Q | S | S | L | R | I | G | I | F | G | A | E | P | W | T | N | D | X | R | V | A | I | E | Q | R | X | G | I | D | A | V | D | I | Y | G |
Template Known Secondary structure |   |
 |  |
|
| S |
|
|  |  |  |  |  |  |  |  |  |  |  |
|
| S |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
| G | G | G | S | S |
|
|  |  |  |  |  | S | S |
|
|
|  |  |  |  |  |  |  |  |  |  |  | T | S |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
159 | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . |
  |
  |   |
336 | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | |
. | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . |
Predicted Secondary structure |   |
|
|  |  |  |
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
S | T | E | S | S | P | H | A | V | V | N | L | D | D | P | L | S | R | F | M | H | T | D | G | Y | A | A | A | G | V | E | I | K | V | V | D | D | A | . |
R | K | T | L | P | P | G | C | E | G | E | E | A | S | R | G | P | N | V | F | M | G | Y | F | D | E | P | E | L | T | A | R | A | L | D | E | E | G | W | Y | Y |
Query Conservation |   |
  |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   | . |   |   |   |   |   |   |
|   |   |
|   |
|   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|
|   |   |   |   |   |   |   |   | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |
|   |   |
|
|
|
|
|
|   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . |
|   |   |   |   |
|   |   |   |
Template Sequence |   |
L | S | E | V | X | G | P | G | V | A | S | . |
. |
. |
E | C | V | E | T | K | D | G | P | T | I | W | E | D | H | F | Y | P | E | I | I | D | P | E | T | G | E | V | L | P | D | G | E | L | G | E | L | V | F | T | S | L | T | K | E | A | L | P | I | I | . |
. |
. |
. |
. |
. |
. |
R | Y | R | T | R | D | L | T | R |
Template Known Secondary structure |   |
 | T | T | T | T |  |  |  |  |  |  | . | . | . |
|
| T | T | T |
| S | S |
|  |  |
| T | T | T |  |  |  |  |  |  |
| T | T | T |
|
| B |
|
| T | T | S |
|  |  |  |  |  |  |  | S | S |
| S | S | S |
|
|
| . | . | . | . | . | . | . | S |  |  |  |  |  |  |  |
|
Template Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |  |
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
|
|
|
|
|
|
|  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
239 | 240 | . | . | . | . | . | . | . | . | . | |
|
|
250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
300 | . | . | . | . | . | . | . | . |
  |
  |   |
415 | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480 | . | . | . | . | . | . | . | . | . | 490 | . | . | |
. |
Predicted Secondary structure |   |
|
|
|  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
|
|  |  |  |  |
|
|  |  |  |
|  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  | . |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
Query Sequence |   |
S | G | D | L | C | R | M | D | E | A | G | Y | I | K | I | T | G | R | K | K | D | I | I | V | R | G | G | E | N | I | S | S | R | E | V | E | D | I | L | L | Q | H | P | K | I | H | D | A | C | V | V | A | M | S | D | E | R | L | G | E | R | S | C | A | Y | V | V | L | K | A | P | H | H | S | L | S | L | E | . |
E |
Query Conservation |   |
|
|
|   |   |   |   |   |   |   |
|   |
|   |
|   |
|
|   |   |
|   |
|   |   |   |
|   |   |
|   |
|   |
|
|
|   |   |
|   |   |   |
|   |
|   |   |   |   |
|   |
|   |   |   |   |   |   |
|   |   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   | . |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|   |   |
|   |   |   |
|   |   |
|   |
|   |   |
|
|   |   |
|   |   |   |   |   |
|   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
L | L | P | G | T | A | R | T | X | R | R | X | E | K | I | T | G | R | S | D | D | X | X | I | V | R | G | V | N | V | F | P | T | Q | I | E | E | Q | L | L | K | Q | R | A | L | A | P | H | Y | Q | I | V | L | T | K | E | G | P | L | D | V | L | T | L | N | V | E | P | C | P | E | T | A | P | D | T | A | A | I | Q |
Template Known Secondary structure |   |
 |  |
|
| S | S | S | S | S |
|  |  |
|
|
|
|  |  | G | G | G |
|  |  |  | T | T |  |  |  |
|  |  |  |  |  |  |  |  | T | T |
| T | T | B |
| S |
|
|  |  |  |  |  |  |  | T | T |  |  |  |  |  |  |  |  |
| B |
| G | G | G | T | T |
|  |  |  |  |  |
Template Predicted Secondary structure |   |
 |
|
|
|
|
|  |  |
|
|
|
|  |  |
|
|
|
|
|
|
|
|  |  |  |
|
|  |  |  |
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
309 | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . |
  |
  |   |
494 | . | . | . | . | . | 500 | . | . | . | . | . | . | . | . | . | 510 | |
|
|
. | . | . | . | . | . | . | . | . | 520 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |
|
|
|
|  |  |
|
|
| . | . | . |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
V | V | A | F | F | S | R | K | R | V | A | K | Y | K | Y | P | E | . |
. |
. |
H | I | V | V | I | E | K | L | P | R | T | T | S | G | K | I | Q | K |
Query Conservation |   |
  |
|   |   |   |   |   |   |   |
|   |   |   |   |   |
|   | . | . | . |   |
|   |   |
|   |   |
|
|   |
|   |   |
|
|
|   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
Template Conservation |   |
  |
|   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |
|
|
|
| . |
|
|
|   |   |
|
Template Sequence |   |
V | A | K | Q | A | L | A | Y | D | I | K | S | L | I | G | V | T | A | V | I | N | V | L | P | V | N | G | I | E | R | S | . |
V | G | K | A | R | R |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
| T | T |
| S |
|
|
| . | S | S | S |
|
|
|
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
| . |
|
|
|  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
389 | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | |
420 | . | . | . | . | . |
  |