|   |
22 | . | . | . | . | . | . | . | 30 | . | |
. | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | |
|
. | . | . | . | . | . | 70 | . | . | . | . | . | |
. | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | |
|
|
|
|
|
Predicted Secondary structure |   |
|
|
|
|
|
|  |  |  |  | . |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|
| . | . |  |  |  |  |  |  |  |  |
|
|
|
| . |
|  |  |
|
|
|
|
|
|
|  |  |  |  |
|
| . | . | . | . | . | . |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
Query Sequence |   |
S | V | F | A | E | A | S | L | T | G | . |
A | G | A | T | F | P | A | P | V | Y | A | K | W | A | D | T | Y | Q | K | E | T | G | N | K | V | N | Y | Q | G | I | G | S | . |
. |
S | G | G | V | K | Q | I | I | A | N | T | V | . |
D | F | G | A | S | D | A | P | L | S | D | E | K | L | A | Q | . |
. |
. |
. |
. |
. |
Query Conservation |   |
  |   |   |
|   |   |   |
|   |   | . |   |
|
|
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |
|
| . | . |
|   |
|
|   |   |   |   |   |
|   |   | . |
|
|
|   |
|
|
|   |
|   |   |   |
|   |   |   | . | . | . | . | . | . |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
Template Conservation |   |
|
|   |
|   |   |
|
|
|
|
|   |   |   |
|   |   |   |   |
|
|   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |
|
|   |   |
|
|   |   |
|
|
|   |
|
|
|
|
|
|   |
|
|
|
|
|   |
|   |   |   |   |
|   |   |
|
|   |   |
|   |
|   |
|
|
Template Sequence |   |
S | K | I | E | E | G | K | L | V | I | W | I | N | G | D | K | G | Y | N | G | L | A | E | V | G | K | K | F | E | K | D | T | G | I | K | V | T | V | E | H | P | D | K | L | E | E | K | F | P | Q | V | A | A | T | G | D | G | P | D | I | I | F | W | A | H | D | R | F | G | G | Y | A | Q | S | G | L | L | A | E | I |
Template Known Secondary structure |   |
|
| S |
| T | T |  |  |  |  |  |
|
| T | T | S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | S |
|  |  |  |  |  |
|
| T | T |  |  |  |  |  |  |  |  |  |  | T | T |
| S |
| S |  |  |  |  |  | G | G | G |  |  |  |  |  |  | T | T |
| B |
|
|
|
Template Predicted Secondary structure |   |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |
|
|
|  |  |  |  |  |  |  |
|
|
|  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
0 | . | . | . | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . |
  |
  |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
92 | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | |
. | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
| . |
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query SS confidence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
E | G | L | F | Q | F | P | T | V | I | G | G | V | V | L | A | V | N | I | P | G | L | K | S | G | E | L | V | L | . |
D | G | K | T | L | G | D | I | Y | L | G | K | I | K | K | W | D | D | E | A | I | A | K | L | N | P | G | L | K |
Query Conservation |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |
|
|   |   |   |
|   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |
| . |
|   |   |
|
|   |   |
|
|   |
|   |
|
|   |
|   |
|   |   |   |   |   |   |
|   |   |   |   |
Alig confidence |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Conservation |   |
|
|   |   |   |   |
|
|   |
|   |
|   |   |
|
|
|   |
|   |
|
|
|
|
|
|
|
|   |   |   |   |   |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |
|   |
|
|
|
|
|   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Sequence |   |
T | P | D | K | A | F | Q | D | K | L | Y | P | F | T | W | D | A | V | R | Y | N | G | K | L | I | A | Y | P | I | A | V | E | A | L | S | L | I | Y | N | K | D | L | L | P | N | P | P | K | T | W | E | E | I | P | A | L | D | K | E | L | K | A | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Template Known Secondary structure |   |
|
|
|  |  |  |  | T | T | B |
|  |  |  |  |  |  | T |  |  | T | T |  |  |
| S |  |  |  |  |  |  |
|
|  |  |  |  |  | T | T | T |
| S | S |
|
| S | B | S | T | T |  |  |  |  |  |  |  |  |  | T | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Predicted Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  |  |  |
|
|  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |
  |   |
150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | |
|
. | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |
|
| . | . |
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
L | P | S | Q | N | I | A | V | V | R | R | A | D | G | S | G | T | S | F | V | F | T | S | Y | L | A | K | V | N | E | E | W | K | N | N | V | G | T | G | S | T | V | K | W | P | I | G | L | G | G | K | G | N | D | G | I | A | A | F | V | Q | R | L | . |
. |
P | G | A | I | G | Y | V | E | Y | A | Y | A | K | Q | N |
Query Conservation |   |
  |
|   |   |   |
|   |
|   |   |
|   |   |   |
|
|
|   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   | . | . |   |
|
|
|
|
|   |   |   |   |   |   |   |   |   |
Alig confidence |   |
. | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
. | . |
|
|   |   |
|   |   |   |
|   |   |
|   |   |   |   |   |   |   |
|   |
|   |
|
|   |   |   |   |   |
|   |
|   |   |
|   |   |   |   |
|
|
|
|
|
|   |
|
|
|
|
|   |
|   |
|
|   |
|   |
|   |
|   |   |   |   |   |   |
|
|
|   |   |   |
|   |
|
Template Sequence |   |
. |
. |
K | G | K | S | A | L | M | F | N | L | Q | E | P | Y | F | T | W | P | L | I | A | A | D | G | G | Y | A | F | K | Y | E | N | G | K | Y | D | I | K | D | V | G | V | D | N | A | G | A | K | A | G | L | T | F | L | V | D | L | I | K | N | K | H | M | N | A | D | T | D | Y | S | I | A | E | A | A | F | N | K |
Template Known Secondary structure |   |
. | . | T | T |
|  |  |  |
|
|
|
| S | S |  |  |  |  |  |  |  |  |  |  | T | T |
|  |  |  |  |  |  | T | T |  |  |  |  |  |  |  |  | S | S | S |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | S | S |
| T | T |
|
|  |  |  |  |  |  |  |  |  | T |
Template Predicted Secondary structure |   |
. | . |
|
|
|
|  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
|
142 | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . |
  |
  |   |
228 | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | |
. | . | . | . |
Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  | . |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
Query Sequence |   |
N | L | A | Y | T | K | L | I | S | A | D | G | K | P | V | S | P | T | E | E | N | F | A | N | A | A | K | G | A | D | W | S | K | T | F | A | Q | D | L | T | N | Q | K | G | E | D | A | W | P | I | T | S | T | T | F | I | L | I | H | K | D | Q | K | K | P | E | Q | G | T | E | V | L | K | F | F | . |
D | W | A | Y |
Query Conservation |   |
  |   |   |   |   |   |
|   |   |   |   |
|   |   |
|   |
|
|   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
| . |   |   |   |
|
Alig confidence |   |
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
| . |
|
|
|
|
Template Conservation |   |
|
|
|
|
|   |
| . | . | . |   |
|
|
|
|   |
|   |
|   |
|
|   |   |
|   |
|
|
|   |
|
|
|   |
|
|   | . | . | . | . | . | . | . | . |   |
|   |   |   |
|
|
|   |
|
|
|
|
|
|   |
|
|
|
|
|
|
| . | . | . |   |
|
|
|
|   |
|
|
|
Template Sequence |   |
G | E | T | A | M | T | I | . |
. |
. |
N | G | P | W | A | W | S | N | I | D | T | S | K | V | N | Y | G | V | T | V | L | P | T | F | K | G | Q | . |
. |
. |
. |
. |
. |
. |
. |
P | S | K | P | F | V | G | V | L | S | A | G | I | N | A | A | S | P | N | K | E | L | A | . |
. |
. |
K | E | F | L | E | N | Y | L | L |
Template Known Secondary structure |   |
T | S |  |  |  |  |  | . | . | . |  |
| G | G | G |  |  |  |  |  |  |  | T |
|
|  |  |  |  |
|
|
| B | B | T | T | B | . | . | . | . | . | . | . | . |
|
|
|
|  |  |  |  |  |  |  |  |  | B | T | T |
| S |
|  |  |  |  | . | . | . |  |  |  |  |  |  | T | T | S |
Template Predicted Secondary structure |   |
|
|
|
|  |  |  | . | . | . |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
| . | . | . | . | . | . | . | . |
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  | . | . | . |  |  |  |  |  |  |  |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
220 | . | . | . | . | . | . | |
|
|
. | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | |
|
|
|
|
|
|
|
. | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | |
|
|
. | . | . | 280 | . | . | . | . | . |
  |
  |   |
307 | |
. | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . |
Predicted Secondary structure |   |
 | . |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
K | . |
T | G | A | K | Q | A | N | D | L | D | Y | A | S | L | P | D | S | V | V | E | Q | V | R | A | A | W |
Query Conservation |   |
| . |
|
|
|   |   |   |   |   |   |
|
|
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
| . |
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|
|
|
|
|
|
|
|   |
|
|   | . | . |
|   |   |   |   |
|   |
|   |   |   |   |   |   |
Template Sequence |   |
T | D | E | G | L | E | A | V | N | K | D | K | . |
. |
P | L | G | A | V | A | L | K | S | Y | E | E | E | L |
Template Known Secondary structure |   |
S |  |  |  |  |  |  |  |  |  |  | S | . | . |
|
|
|  |  | S | B |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|  |  |  |  |  |  |  |  |  |
|
| . | . |
|
|
|  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
286 | . | . | . | 290 | . | . | . | . | . | . | . | |
|
. | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . |
  |