|   |
24 | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | |
|
|
|
|
|
. | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | |
|
. | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . |
|
|
|  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |
|
| . | . |
|
|
|  |  |
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
F | A | E | A | S | L | T | G | A | G | A | T | F | P | A | P | V | Y | A | K | W | A | D | T | Y | Q | K | E | . |
. |
. |
. |
. |
. |
T | G | N | K | V | N | Y | Q | G | I | G | S | S | G | G | V | K | Q | I | I | A | N | . |
. |
T | V | D | F | G | A | S | D | A | P | L | S | D | E | K | L | A | Q | E | G | L | F |
Query Conservation |   |
  |
|   |   |   |
|   |   |   |
|
|
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . |   |   |   |   |
|   |   |   |   |   |
|
|
|   |
|
|   |   |   |   |   |
| . | . |   |   |
|
|
|   |
|
|
|   |
|   |   |   |
|   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |   |   |   |
|
|
|   |   |   |
|
|   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
Template Sequence |   |
S | R | E | A | R | L | I | I | F | H | A | G | S | L | S | I | P | L | S | Q | V | E | E | K | F | T | K | Y | A | Q | E | K | L | G | V | K | V | T | F | Q | D | E | A | S | G | S | V | K | A | V | R | K | V | T | D | L | K | K | R | A | D | I | V | A | V | A | D | Y | T | L | I | P | Q | L | M | I | P | N | Y | T |
Template Known Secondary structure |   |
|
|  |  |  |  |  |  |  |  |  | G | G | G |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |
|  |  |  |  |  |  |  |  |  | T | S |
|
|
|
| S |  |  |  |  | S | S | T | T |  |  |  |  |  | T | T | T | T | T |
|
Template Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
25 | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . |
  |
  |   |
96 | |
|
. | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . |
Predicted Secondary structure |   |
 | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |
Query SS confidence |   |
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
Q | . |
. |
F | P | T | V | I | G | G | V | V | L | A | V | N | I | P | G | L | K | S | G | E | L | V | L | D | G | K | T | L | G | D | I | Y | L | G | K | I | K | K | W | D | D | E | A | I | A | K | L | N | P | G | L | K | L | P | S | Q | N | I | A | V | V | R | R | A | D | G | S | G | T | S | F | V | F | T | S | Y |
Query Conservation |   |
  | . | . |   |   |
|
|   |   |   |
|   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |
|
|   |   |
|
|   |
|   |
|
|   |
|   |
|   |   |   |   |   |   |
|   |   |   |   |   |
|   |   |   |
|   |
|   |   |
|   |   |   |
|
|
|   |   |   |
|   |   |   |
Alig confidence |   |
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
D | F | Y | V | L | F | A | T | N | E | I | V | I | A | F | T | N | K | S | K | Y | A | D | E | M | L | K | N | P | D | K | W | Y | E | I | L | S | R | P | D | V | S | F | G | F | S | D | P | N | Q | D | P | C | G | Y | R | S | V | M | V | M | K | L | A | E | L | Y | Y | G | R | P | I | F | K | E | L | V | E | K | T |
Template Known Secondary structure |   |
S |  |  |  |  |  |  |  |
|
|  |  |  |  |  |
| T | T | S | T | T |  |  |  |  |  |  |
| G | G | G |  |  |  |  | T | T |
| T | T |
|
|  |  |  |  |
| T | T | T |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| S |
|  |  |  |  |  | T | T | T | T |
Template Predicted Secondary structure |   |
|
|
|  |  |  |
|
|
|
|
|
|  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
105 | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . |
  |
  |   |
174 | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . |
Predicted Secondary structure |   |
 |  |
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
L | A | K | V | N | E | E | W | K | N | N | V | G | T | G | S | T | V | K | W | P | I | G | L | G | G | K | G | N | D | G | I | A | A | F | V | Q | R | L | P | G | A | I | G | Y | V | E | Y | A | Y | A | K | Q | N | N | L | A | Y | T | K | L | I | S | A | D | G | K | P | V | S | P | T | E | E | N | F | A | N | A | A |
Query Conservation |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |
|
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|   |   |
|   |
|
|   |   |   |
|   |   |
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
T | N | I | Y | S | N | G | T | R | I | Y | A | P | K | E | I | I | I | K | D | K | R | V | I | M | R | P | K | E | T | D | L | V | G | L | V | E | S | G | S | L | D | Y | I | F | I | Y | K | S | V | A | K | Q | H | H | L | S | Y | I | T | L | . |
. |
. |
. |
. |
. |
. |
. |
. |
P | D | D | I | N | L | G | D | F | N |
Template Known Secondary structure |   |
B | S |
|  |  |  | T | T |  |  |  |  |
| S | S |
|
| B | S | S | T | T |  |  |  |  | S | S | T |  |  |  |  |  |  |  |  | T | T | S | S |
|  |  |  |  |  |  |  |  |  |  |  | T | T |
|  |  |  |  |
| . | . | . | . | . | . | . | . | . |
| T | T | T | S | S |
|
| G | G |
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|  |  |  |  |  |
|
|
|
|  |  |  |  | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
185 | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | |
|
|
|
|
|
|
|
|
. | . | . | . | 250 | . | . | . | . | . |
  |
  |   |
254 | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | |
. | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
K | G | A | D | W | S | K | T | F | A | Q | D | L | T | N | Q | K | G | E | D | A | W | P | I | T | S | T | T | F | I | L | I | H | K | D | Q | K | K | P | E | Q | G | T | E | V | L | K | F | F | D | W | A | Y | K | . |
T | G | A | K | Q | A | N | D | L | D | Y | A | S | L |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|   |   |   |
|
| . |
|
|
|   |   |   |   |   |   |
|
|
|
|
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
| . | . | . | . | . |   |   |   |
|   |
|   |
|
|
|   |   |
|
|   |
|
|   |
|   |
|   |
|   |   |   |   |   |   |
|   |   |
|   |
Template Sequence |   |
K | A | D | F | Y | G | R | V | S | I | T | L | G | S | T | G | K | T | I | K | A | K | P | I | V | Y | G | I | T | V | . |
. |
. |
. |
. |
L | K | N | A | P | N | R | E | L | A | I | E | F | L | R | F | L | L | G | N | E | G | R | K | I | F | E | D | N | Y | Q | E | F | L |
Template Known Secondary structure |   |
G |  |  |  |  | T | T |
|  |  |  |  | T | T | T |
|
|  |  |  |
|
|
|
|  |  |  |  |  |  | . | . | . | . | . |
| T | T |
| T | T |  |  |  |  |  |  |  |  |  |  |  |  | S |  |  |  |  |  |  |  |  |  | T | T |
|
|  |  |
Template Predicted Secondary structure |   |
 |
|
|
|
|
|
|
|
|
|  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  | . | . | . | . | . |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
256 | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | |
|
|
|
|
. | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . |
  |