|   |
9 | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|  |  |  |  |  |  |  |
|
|
|  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | G | Q | I | L | N | S | L | I | N | S | I | L | L | I | D | D | N | L | A | I | H | Y | A | N | P | A | A | Q | Q | L | L | A | Q | S | S | R | K | L | F | G | T | P | L | P | E | L | L | S | Y | F | S | L | N | I | E | L | M | Q | E | S | L | E | A | G | Q | G | F | T | D | N | E | V | T | L | V | I | D | G | R |
Query Conservation |   |
  |   |   |
|
|
|   |   |
|   |
|
|   |
|   |
|   |   |
|   |
|   |   |   |
|   |
|   |   |   |
|   |
|   |   |   |   |
|
|
|
|   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |   |
|   |
|   |   |   |   |
|
|   |
|   |
|   |   |
|   |
|   |   |   |
|   |
|   |   |   |
|   |
|   |   |   |
|
|
|
|
|   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
S | E | S | I | L | E | S | L | E | T | A | I | I | T | L | S | K | D | G | R | I | T | E | W | N | K | K | A | E | Q | L | F | G | L | K | K | E | N | V | L | G | R | R | L | K | D | L | P | D | F | E | E | I | G | S | V | A | E | S | V | F | E | N | K | E | P | V | F | L | N | F | Y | K | F | G | E | R | Y | F | N |
Template Known Secondary structure |   |
|
| S | S | G | G | G | S | S | S |  |  |  |  |  |  | S | S | S | B |
| S |
| B |
|  |  |  |  |  |  |  | S |
|
| S | T | T | T | T | T |
| B | S | T | T | S | T | T | T | T |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
| B | T | T | B |
|
|  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|  |  |  |  |  |  |  |
|
|
|  |  |  |  |
|
|
|
|  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
416 | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480 | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . |
  |
  |   |
89 | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | |
|
|
|
|
. | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
S | H | I | L | S | V | T | A | Q | R | M | P | D | G | M | I | L | L | E | M | A | P | M | D | N | Q | R | R | L | S | Q | E | Q | L | Q | H | A | Q | Q | V | A | A | R | D | L | V | R | G | L | A | H | E | I | K | N | P | . |
. |
. |
. |
. |
L | G | G | L | R | G | A | A | Q | L | L | S | K | A | L | P | D | P | S |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
I | R | F | S | P | F | R | N | A | K | T | Q | L | L | E | G | V | I | I | T | I | D | D | V | T | E | L | Y | K | Y | E | E | E | R | K | R | R | E | R | L | S | I | L | G | E | M | T | A | R | V | A | H | E | I | R | N | P | I | T | I | I | G | G | F | I | M | R | M | K | K | H | L | D | D | P | E | T | L | K | K |
Template Known Secondary structure |   |
 |  |  |  |  |  |
|
| T | T | T | T | S | S |
|  |  |  |  |  |  |  |
|
| S | T | T | T | T | T | T | T | T | T | T |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | S |
| S |
| S | S |
| T | T |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
496 | . | . | . | 500 | . | . | . | . | . | . | . | . | . | 510 | . | . | . | . | . | . | . | . | . | 520 | . | . | . | . | . | . | . | . | . | 530 | . | . | . | . | . | . | . | . | . | 540 | . | . | . | . | . | . | . | . | . | 550 | . | . | . | . | . | . | . | . | . | 560 | . | . | . | . | . | . | . | . | . | 570 | . | . | . | . | . |
  |
  |   |
164 | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
L | L | E | Y | T | K | V | I | I | E | Q | A | D | R | L | R | N | L | V | D | R | L | L | G | P | Q | L | P | G | T | R | V | T | E | S | I | H | K | V | A | E | R | V | V | T | L | V | S | M | E | L | P | D | N | V | R | L | I | R | D | Y | D | P | S | L | P | E | L | A | H | D | P | D | Q | I | E | Q | V | L | L |
Query Conservation |   |
  |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
Y | I | N | I | I | T | N | E | L | S | R | L | E | T | I | V | K | E | I | L | E | Y | S | K | E | R | V | L | E | F | T | E | F | N | L | N | E | L | I | R | E | V | Y | V | L | F | E | E | K | I | R | K | M | N | I | D | F | C | F | E | T | D | N | E | D | L | R | V | E | A | D | R | T | R | I | K | Q | V | L | I |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | T | T |
|
|
|  |  |  |  | S |
| S |
|
|  |  |  |  |
|  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
576 | . | . | . | 580 | . | . | . | . | . | . | . | . | . | 590 | . | . | . | . | . | . | . | . | . | 600 | . | . | . | . | . | . | . | . | . | 610 | . | . | . | . | . | . | . | . | . | 620 | . | . | . | . | . | . | . | . | . | 630 | . | . | . | . | . | . | . | . | . | 640 | . | . | . | . | . | . | . | . | . | 650 | . | . | . | . | . |
  |
  |   |
244 | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
N | I | V | R | N | A | L | Q | A | L | G | P | E | G | G | E | I | I | L | R | T | R | T | A | F | Q | L | T | L | H | G | E | R | Y | R | L | A | A | R | I | D | V | E | D | N | G | P | G | I | P | P | H | L | Q | D | T | L | F | Y | P | M | V | S | G | R | E | G | G | T | G | L | G | L | S | I | A | R | N | L | I |
Query Conservation |   |
  |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |
|   |
|   |
|   |
|
|   |   |
|   |   |   |   |
|
|   |
|
|   |
|
|
|   |   |
|
|
|
|
|
|   |
|   |
|   |
|
|
Alig confidence |   |
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|
|   |   |
|
|   |   |   | . |   |   |   |   |   |   |
|   |   |   |   |   | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |
|   |
|   |
|   |
|   |
|   |
|
|   |   |   |   |   |   |   |
|
|
|
|
|   | . | . | . | . | . | . |
|
|
|
|
|   |
|
|   |   |
|
|
Template Sequence |   |
N | L | V | Q | N | A | I | E | A | . |
T | G | E | N | G | K | I | K | I | T | S | E | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
D | M | Y | T | K | V | R | V | S | V | W | N | S | G | P | P | I | P | E | E | L | K | E | K | I | F | S | P | F | F | . |
. |
. |
. |
. |
. |
T | T | L | G | L | S | I | C | R | K | I | I |
Template Known Secondary structure |   |
 |  |  | T |  |  |  |  | T | . | T |
| T | T |
|
|  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . |  |  | T | T |  |  |  |  |  |  |  |  |  | S |
|
|
|
| G | G | G | G | T | T | T | S | S | S |
|
| . | . | . | . | . | . |
|
|
|
|
| T |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|
|  |  |  |  |
| . |
|
|
|
|
|  |  |  |  |  |  |
| . | . | . | . | . | . | . | . | . | . |
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
| . | . | . | . | . | . |
|
|  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
657 | . | . | 660 | . | . | . | . | . | |
. | . | . | . | 670 | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
. | . | 680 | . | . | . | . | . | . | . | . | . | 690 | . | . | . | . | . | . | . | . | . | 700 | . | . | . | . | . | . | . | |
|
|
|
|
|
. | . | 710 | . | . | . | . | . | . | . | . | . |
  |
  |   |
324 | |
. | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 | . |  |
|
|
|  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |
|
Query SS confidence |   |
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
D | . |
Q | H | S | G | K | I | E | F | T | S | W | P | G | H | T | E | F | S | V | Y | L | P | I | R | K |
Query Conservation |   |
  | . |   |
|
|
|   |
|   |
|   |
|   |   |
|
|
|   |
|   |
|   |
|
|   |   |   |
Alig confidence |   |
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |
|
|
|   |
|   |
|   |
|   |   |   |
|
|   |
|   |
|   |
|
|   |   |   |
Template Sequence |   |
E | D | E | H | G | G | K | I | W | T | E | N | R | E | N | G | V | V | F | I | F | E | I | P | K | T | P |
Template Known Secondary structure |   |
 |  | T | T |
| S | B |
|
|  |  |  |
| S | S |  |  |  |  |  |  |  |  |  | S |
| T |
Template Predicted Secondary structure |   |
 |  |  |
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
726 | . | . | . | 730 | . | . | . | . | . | . | . | . | . | 740 | . | . | . | . | . | . | . | . | . | 750 | . | . |
  |