|   |
21 | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | |
. | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . |
|
|  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
V | L | T | V | Y | T | Y | D | S | F | A | A | D | W | G | P | G | P | V | V | K | K | A | F | E | A | D | C | . |
N | C | E | L | K | L | V | A | L | E | D | G | V | S | L | L | N | R | L | R | M | E | G | K | N | S | K | A | D | V | V | L | G | L | D | N | N | L | L | D | A | A | S | K | T | G | L | F | A | K | S |
Query Conservation |   |
|
|
|
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|
|   |   |   | . |
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|
|   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |
|   |   |   |
|
|   |   |   |
|   |
|   |
|   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . |   |   |   |   |   |
|   |   |
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |
|
|
Template Sequence |   |
T | L | K | V | A | I | Y | P | Y | V | P | D | P | A | R | F | Q | A | A | V | L | D | Q | W | Q | R | Q | E | P | G | V | K | L | E | F | T | D | W | D | S | . |
. |
. |
. |
. |
. |
. |
. |
. |
Y | S | A | D | P | P | D | D | L | D | V | F | V | L | D | S | I | F | L | S | H | F | V | D | A | G | Y | L | L | P | F |
Template Known Secondary structure |   |
 |  |  |  |  |
|
| S |
| S | S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| T | T | S |  |  |  |  |
|
|
|
| T | . | . | . | . | . | . | . | . | . | T | T |
|
|
|
| T | T |
|
|  |  |  |  |  | G | G | G |  |  |  |  |  |  | T | T |
|  |  |
| B |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
| . | . | . | . | . | . | . | . | . |  |  |  |
|
|
|
|
|
|
|  |  |  |  |
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 |
  |
  |   |
100 | . | |
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . |
Predicted Secondary structure |   |
|
| . | . | . | . | . | . | . | . | . |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|  | . | . | . | . | . | . | . | . | . | . | . | . |  |  |
|
|
|
Query SS confidence |   |
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
Query Sequence |   |
G | V | . |
. |
. |
. |
. |
. |
. |
. |
. |
A | A | D | A | V | N | V | P | G | G | W | N | N | D | T | F | V | P | F | D | Y | G | Y | F | A | F | V | Y | D | K | N | K | L | K | N | P | P | Q | S | L | K | E | L | V | E | S | D | Q | N | W | R | V | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
I | Y | Q | D | P |
Query Conservation |   |
  |   | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|   |   |   |   |   |   |   |
|   |
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |
Alig confidence |   |
|
| . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |
|
|   |   |   |   |   |   |   |
|   |
|
|
|
|   |   |   |   |
|
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
G | S | Q | D | I | D | Q | A | E | D | V | L | P | F | A | L | Q | G | A | K | R | N | G | E | V | Y | G | L | P | Q | I | L | C | T | N | L | L | F | Y | R | K | G | D | L | K | I | G | Q | V | D | N | I | Y | E | L | Y | K | K | I | G | T | S | H | S | E | Q | I | P | P | P | Q | N | K | G | L | L | I | N | M | A |
Template Known Secondary structure |   |
| G | G | G |
| T | T | G | G | G | B |
|  |  |  |  |  |  | T |  |  | T | T |  |  |
|
|  |  |  |  |  |  |
|  |  |  |  |  |  | T | T |
|  |  |  |  | T |
|
| B |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
| S | S |
|
|  |  |  |  |  |  |  |
|
|
|
Template Predicted Secondary structure |   |
|  |  |  |  |
|
|  |  |  |
|
|  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
81 | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 |
  |
  |   |
159 | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
R | T | S | T | P | G | L | G | L | L | L | W | M | Q | K | V | Y | G | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
D | D | A | P | Q | A | W | Q | K | L | A | K | K | T | V | T | V | T | K | G | W | S | E | A | Y | G | L | F | L | K | G | E | S | D | L | V | L | S | Y | T |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |
Template Sequence |   |
G | G | T | T | K | A | S | M | Y | L | E | A | L | I | D | V | T | G | Q | Y | T | E | Y | D | L | L | P | P | L | D | P | L | N | D | K | V | I | R | G | L | R | L | L | I | N | M | A | G | E | K | P | S | Q | Y | V | P | E | D | G | D | A | Y | V | R | A | S | W | F | A | Q | G | S | G | R | A | F | I | G | Y | S |
Template Known Secondary structure |   |
S |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
|
|
|
|
| S | S |
|
|
| S | S | S |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  |  |  |  |  |
|
|
| T | T |
|
| T | T |  |  |  |  |  |  |  |  | T | B |  |  |  |  |  |  |  | T |
Template Predicted Secondary structure |   |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
161 | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 |
  |
  |   |
217 | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | |
|
|
240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . |
Predicted Secondary structure |   |
|  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
| . | . | . |
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
T | S | P | A | Y | H | I | L | E | E | K | K | D | N | Y | A | A | A | N | F | S | E | G | . |
. |
. |
H | Y | L | Q | V | E | V | A | A | R | T | A | A | S | K | Q | P | E | L | A | Q | K | F | L | Q | F | M | V | S | P | A | F | Q | N | A | I | P | T | G | N | W | M | Y | P | V | A | N | V | T | L | P | A | G | F |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
| . | . | . |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |
|   |   |
|
|   |
|
|   |
|   |
|   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |
|   |
|   |   |
|
|   |
|
|   |
|   |
|   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |
|   |   |   |
Template Sequence |   |
E | S | M | M | R | M | G | D | Y | A | E | Q | V | R | F | K | P | I | S | S | S | A | G | Q | D | I | P | L | F | Y | S | D | V | V | S | V | N | S | K | T | A | H | P | E | L | A | K | K | L | A | N | V | M | A | S | A | D | T | V | E | Q | A | L | R | P | Q | A | D | G | Q | Y | P | Q | Y | L | L | P | A | R | H |
Template Known Secondary structure |   |
T |  |  |  |  |  | G | G | G | G | G | T |  |  |  |  |
|
| B | S |
| S | S |
|
|
|
|  |  |  |  |  |  |  |  |  |  | T | T |
| S |
|  |  |  |  |  |  |  |  |  |  |  |  | S |  |  |  |  |  |  |  |  | S |
|
| S | T | T |
|
|
|
|
|
|  |  | S | B |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
241 | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 |
  |
  |   |
294 | . | . |
Predicted Secondary structure |   |
 |  |  |
Query SS confidence |   |
|
|
|
Query Sequence |   |
E | K | L |
Query Conservation |   |
  |   |   |
Alig confidence |   |
|
|
|
Template Conservation |   |
  |   |   |
Template Sequence |   |
Q | V | Y |
Template Known Secondary structure |   |
 |  |  |
Template Predicted Secondary structure |   |
 |  |  |
Template SS confidence |   |
|
|
|
  |   |
321 | . | . |
  |