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Job DescriptionP75895
Confidence99.65%DateThu Jan 5 12:15:46 GMT 2012
Rank157Aligned Residues216
% Identity15%Templatec2qtbB_
PDB info PDB header:hydrolaseChain: B: PDB Molecule:dipeptidyl peptidase 4; PDBTitle: human dipeptidyl peptidase iv/cd26 in complex with a 4-aryl2 cyclohexylalanine inhibitor
Resolution2.25 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


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Query Sequence  MKLSLSPP. . . . PYADAPVVVLISGLGG. . . . . SGSYWLPQLAVLEQ. EYQVVCYDQRGTGNN. . . . . . . PDTLAEDYSI
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Template Sequence  FWYQMILPPHFDKSKKYPLLLDVYAGPCSQKADTVFRLNWATYLASTENIIVASFDGRGSGYQGDKIMHAINRRLGTFEV
Template Known Secondary structure 
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TT
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GGGTT
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   524.....530.........540.........550.........560.........570.........580.........590.........600...
 
   64.....70...... ...80.........90.........100.........110.........120.........130.........140.
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Query Sequence  AQMAAELHQALVA. . AGIEHYAVVGHALGALVGMQLALDYPASVTVLISVNGWLRINAHTRRCFQVRERLLYSGGAQAWV
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Template Sequence  EDQIEAARQFSKMGFVDNKRIAIWGWSYGGYVTSMVLGSGSGVFKCGIAVAPVS. . . . . . . . . . . . . . . . . . . . . . . . . .
Template Known Secondary structure  TTSSTTTT
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   604.....610.........620.........630.........640.........650.......
 
   142.......150.........160.........170.........180.........190........ .200.........210.........220
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Query Sequence  EAQPLFLYPADWMAARAPRLEAEDALALAHFQGKNNLLRRLNALKRADFSHHADRIR. CPVQIICASDDLLVPTACSSEL
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Template Sequence  . . . . . . . . . . . . . . . . . . RWEYYDSVYTERYMGLPTPEDNLDHYRNSTVMSRAENFKQVEYLLIHGTADDNVHFQQSAQI
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GGGSB

SSTTTTS
SGGGGGGGGGSTT
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T
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   658.660.........670.........680.........690.........700.........710.........
 
   221... .....230.........240. ........250.........260
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Query Sequence  HAAL. . . . PDSQKMVMPYGGHACNV. TDPETFNALLLNGLASLLH
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Template Conservation     
   
            
                 
    
 
Template Sequence  SKALVDVGVDFQAMWYTDEDHGIASSTAHQHIYTHMSHFIKQCFS
Template Known Secondary structure  TT


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   720.........730.........740.........750.........760....
 
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No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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