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Job DescriptionP75895
Confidence99.70%DateThu Jan 5 12:15:46 GMT 2012
Rank152Aligned Residues216
% Identity15%Templatec2g5tA_
PDB info PDB header:hydrolaseChain: A: PDB Molecule:dipeptidyl peptidase 4; PDBTitle: crystal structure of human dipeptidyl peptidase iv (dppiv)2 complexed with cyanopyrrolidine (c5-pro-pro) inhibitor 21ag
Resolution2.30 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


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Query Sequence  MKLSLSPPP. . . . YADAPVVVLISGLGG. . . . . SGSYWLPQLAVLEQ. EYQVVCYDQRGTGNNP. . . . . . . DTLAEDYSI
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Template Sequence  FWYQMILPPHFDKSKKYPLLLDVYAGPCSQKADTVFRLNWATYLASTENIIVASFDGRGSGYQGDKIMHAINRRLGTFEV
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   524.....530.........540.........550.........560.........570.........580.........590.........600...
 
   64.....70...... ...80.........90.........100.........110.........120.........130.........140.
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Query Sequence  AQMAAELHQALVA. . AGIEHYAVVGHALGALVGMQLALDYPASVTVLISVNGWLRINAHTRRCFQVRERLLYSGGAQAWV
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Template Sequence  EDQIEAARQFSKMGFVDNKRIAIWGWSYGGYVTSMVLGSGSGVFKCGIAVAPVS. . . . . . . . . . . . . . . . . . . . . . . . . .
Template Known Secondary structure  TTSSSTTS




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   604.....610.........620.........630.........640.........650.......
 
   142.......150.........160.........170.........180.........190........ .200.........210.........220
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Query Sequence  EAQPLFLYPADWMAARAPRLEAEDALALAHFQGKNNLLRRLNALKRADFSHHADRIR. CPVQIICASDDLLVPTACSSEL
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Template Sequence  . . . . . . . . . . . . . . . . . . RWEYYDSVYTERYMGLPTPEDNLDHYRNSTVMSRAENFKQVEYLLIHGTADDNVHFQQSAQI
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   658.660.........670.........680.........690.........700.........710.........
 
   221... .....230......... 240.........250.........260
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Query Sequence  HAAL. . . . PDSQKMVMPYGGHAC. NVTDPETFNALLLNGLASLLH
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Template Sequence  SKALVDVGVDFQAMWYTDEDHGIASSTAHQHIYTHMSHFIKQCFS
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   720.........730.........740.........750.........760....
 
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No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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