|   |
129 | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | |
|
|
|
. | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
| . | . | . | . |
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
D | E | R | W | R | E | A | I | V | T | R | S | P | L | M | L | R | L | L | E | Q | A | R | L | V | A | Q | S | D | V | S | V | L | I | N | G | Q | S | G | T | G | K | E | I | F | A | Q | A | I | H | N | A | S | P | . |
. |
. |
. |
R | N | S | K | P | F | I | A | I | N | C | G | A | L | P | E | Q | L | L | E | S | E |
Query Conservation |   |
  |   |   |   |   |   |   |
|
|
|   |
|   |
|
|   |   |
|   |   |   |
|   |   |   |
|   |   |   |   |
|
|
|
|   |
|
|   |
|
|
|
|   |   |   |
|   |   |
|
|   |   |
|   | . | . | . | . |   |   |   |   |   |
|   |   |
|   |
|   |   |
|   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|   |   |   |   |
|
|
|
|   |
|   |   |   |   |   |
|   |   |   |
|   |   | . | . |   |   |   |   |   |
|
|
|   |
|
|   |
|   |
|
|
|   |
|
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
R | P | K | N | L | D | E | V | T | A | Q | D | H | A | V | T | V | L | K | K | T | L | K | S | . |
. |
A | N | L | P | H | M | L | F | Y | G | P | P | G | T | G | K | T | S | T | I | L | A | L | T | K | E | L | Y | G | P | D | L | M | K | S | R | I | L | E | L | N | A | S | D | E | R | G | I | S | I | V | R | E | K |
Template Known Secondary structure |   |
|
| S | S | T | T | T |
|
| S |
|
| T | T |  |  |  |  |  |  |  | T | T |
| . | . | T | T |
|
|
|  |  |  |  |
| S | T | T | S | S |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | S |  |  |  |  |
| S | S | S |
|
|
|  |  |  |  | T | T |  |
Template Predicted Secondary structure |   |
|
|
|
|  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
| . | . |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
32 | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | |
|
. | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . |
  |
  |   |
205 | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . |
Predicted Secondary structure |   |
 |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|  |  |  |  |  |
|  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |
|
|
|
|
|  |  |
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
L | F | G | H | A | R | G | A | F | T | G | A | V | S | N | R | E | G | L | F | Q | A | A | E | G | G | T | L | F | L | D | E | I | G | D | M | P | A | P | L | Q | V | K | L | L | R | V | L | Q | E | R | K | V | R | P | L | G | S | N | R | D | I | D | I | N | V | R | I | I | S | A | T | H | R | D | L | P | K | A | M |
Query Conservation |   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|   |   |
|
|
|   |
|   |   |
|   |   |
|   |   |   |   |
|   |   |
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|   |   |
|   |   |   |
|   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |
|   |   |   |   |   | . | . | . | . | . | . |
Template Sequence |   |
V | K | N | F | A | R | L | T | V | S | K | P | S | K | H | D | L | E | N | Y | P | C | P | P | Y | K | I | I | I | L | D | E | A | D | S | M | T | A | D | A | Q | S | A | L | R | R | T | M | E | T | Y | S | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
G | V | T | R | F | C | L | I | C | N | Y | . |
. |
. |
. |
. |
. |
Template Known Secondary structure |   |
 |  |  |  |  |  | S |
|
|
|
|
|
| T | T |  |  |  |  | S |
|
|
| S |
|  |  |  |  |  | T | T | G | G | G | S |
|  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | . | . | . | . | . | . | . | . | . | . | . | T | T |  |  |  |  |  |  |  | S |
| . | . | . | . | . | . |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
| . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|  |  |  |  |  |  |  | . | . | . | . | . | . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | |
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | . | 170 | . | . | |
|
|
|
|
|
  |
  |   |
285 | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . |
Predicted Secondary structure |   |
 |
|
|
|
|
|  |  |  |  |  |  |
|
|  |  |  |  |  |  |
|
|  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | R | G | E | F | R | E | D | L | Y | Y | R | L | N | V | V | S | L | K | I | P | A | L | A | E | R | T | E | D | I | P | L | L | A | N | H | L | L | R | Q | A | A | E | R | H | K | P | F | V | R | A | F | S | T | D | A | M | K | R | L | M | T | A | S | W | P | G | N | V | R | Q | L | V | N | V | I | E | Q | C | V |
Query Conservation |   |
  |   |   |   |
|   |   |   |
|   |   |   |
|   |   |   |   |
|   |
|
|   |
|
|
|
|   |
|
|
|   |   |
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |
|   |   |   |   |
|
|
|
|   |   |
|
|   |   |   |
|   |   |   |   |
Alig confidence |   |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
. |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . |   |   |   |   |
|   |   |   |   |   |   |   |   |   | . | . | . |   |   |   |   |   |   |
|   |   |
|   |   |   | . |   |   |
|
|   |
|   |   |
|   |   |
|   |   |
|   |
Template Sequence |   |
. |
V | T | R | I | I | D | P | L | A | S | Q | C | S | K | F | R | F | K | A | L | D | A | S | N | . |
. |
. |
. |
. |
. |
. |
. |
A | I | D | R | L | R | F | I | S | E | Q | E | N | V | . |
. |
. |
K | C | D | D | G | V | L | E | R | I | L | D | I | . |
S | A | G | D | L | R | R | G | I | T | L | L | Q | S | A | S |
Template Known Secondary structure |   |
. | G | G | G | S |
|  |  |  |  |  |  | S |  |  |  |  |
|
|
|
|
|  |  |  | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  | T | T | T |
| . | . | . |
|
|
|  |  |  |  |  |  |  |  |  |  | . | T | S | S |
|  |  |  |  |  |  |  |  |  |  | T |  |
Template Predicted Secondary structure |   |
. |  |  |
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |
|
|
|
| . | . | . |
|
|
|  |  |  |  |  |  |  |  |  |  | . |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
173 | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | |
|
|
|
|
|
|
|
. | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | |
|
|
. | . | . | . | . | . | . | . | . | 220 | . | . | . | |
. | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . |
  |
  |   |
365 | . | . | |
|
|
|
. | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . |
Predicted Secondary structure |   |
 |  |
| . | . | . | . |
|
|
|
|
|
|  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | L | T | . |
. |
. |
. |
S | S | P | V | I | S | D | A | L | V | E | Q | A | L |
Query Conservation |   |
  |   |   | . | . | . | . |   |   |   |   |
|   |   |   |   |
|   |   |   |   |
Alig confidence |   |
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |
|   |   |   |   |   |   |   |   |
|
|   |   |   |
|   |
|   |   |
Template Sequence |   |
K | G | A | Q | Y | L | G | D | G | K | N | I | T | S | T | Q | V | E | E | L | A |
Template Known Secondary structure |   |
 |  |  |  |  |  |
| S |
|
|
|
|
|  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 |
  |